Biomechanical Characterization And Simulation Of The Tricuspid Valve
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Biomechanical Characterization And Simulation Of The Tricuspid Valve
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Author : Keyvan Amini Khoiy
language : en
Publisher:
Release Date : 2018
Biomechanical Characterization And Simulation Of The Tricuspid Valve written by Keyvan Amini Khoiy and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Heart categories.
The tricuspid valve, which is located on the right side of the heart, prevents blood backflow from the right ventricle to the right atrium. Regurgitation in this valve occurs when its leaflets do not close normally. Tricuspid valve regurgitation is one of the most common tricuspid valve dysfunctions, often requiring valve repair or replacement. The long-term success rate of the repair surgeries has not been promising; in many cases, reoperations are required within a few years after the first surgery. A limiting factor in understanding the etiology of tricuspid valve repair failure is our lack of knowledge regarding tricuspid valve biomechanics. In particular, tricuspid valve mechanical behavior has not been accurately studied. In addition, there is no precise analytical and/or computerized model to predict the mechanical responses of the valve under normal and pathological conditions. In the current study, we have used biaxial tensile testing, small angle light scattering, ex-vivo passive heart beating simulation, and sonomicrometry techniques to quantify the mechanical characteristics, microstructure, dynamic deformations, and geometric parameters of the tricuspid valve. We aimed to develop a more accurate computerized model of the tricuspid valve for simulation purposes. Our studies are important both for understanding the normal valvular function as well as for development/improvement of surgical procedures and medical devices.
Advances In Heart Valve Biomechanics
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Author : Michael S. Sacks
language : en
Publisher: Springer
Release Date : 2019-04-08
Advances In Heart Valve Biomechanics written by Michael S. Sacks and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-08 with Science categories.
This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.
The Tricuspid Valve
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Author : Devin William Laurence
language : en
Publisher:
Release Date : 2022
The Tricuspid Valve written by Devin William Laurence and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Biomechanics categories.
Experimental Testing Image Based Analysis And Finite Element Simulation Of The Tricuspid Valve
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Author : Colton Jay Ross
language : en
Publisher:
Release Date : 2023
Experimental Testing Image Based Analysis And Finite Element Simulation Of The Tricuspid Valve written by Colton Jay Ross and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with Biomechanics categories.
Frontiers In Computational Fluid Structure Interaction And Flow Simulation
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Author : Tayfun E. Tezduyar
language : en
Publisher: Springer Nature
Release Date : 2023-11-01
Frontiers In Computational Fluid Structure Interaction And Flow Simulation written by Tayfun E. Tezduyar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-01 with Mathematics categories.
Computational fluid-structure interaction (FSI) and flow simulation are challenging research areas that bring solution and analysis to many classes of problems in science, engineering, and technology. Young investigators under the age of 40 are conducting much of the frontier research in these areas, some of which is highlighted in this volume. The first author of each chapter took the lead role in carrying out the research presented. Some of the topics explored include Direct flow simulation of objects represented by point clouds Computational investigation of leaflet flutter in thinner biological heart valve tissues High-fidelity simulation of hydrokinetic energy applications High-resolution isogeometric analysis of car and tire aerodynamics Computational analysis of air-blast-structure interaction Heart valve computational flow analysis with boundary layer and leaflet contact representation Computational thermal multi-phase flow for metal additive manufacturing This volume will be a valuable resource for early-career researchers and students — not only those interested in computational FSI and flow simulation, but also other fields of engineering and science, including fluid mechanics, solid mechanics, and computational mathematics – as it will provide them with inspiration and guidance for conducting their own successful research. It will also be of interest to senior researchers looking to learn more about successful research led by those under 40 and possibly offer collaboration to these researchers.
Tricuspid Valve Reconstruction Using Porcine Extracellular Matrix Functional And Biomechanical Aspects
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Author :
language : en
Publisher:
Release Date :
Tricuspid Valve Reconstruction Using Porcine Extracellular Matrix Functional And Biomechanical Aspects written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
A Multiscale Framework To Analyze Tricuspid Valve Biomechanics
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Author : Vineet Sunny Thomas
language : en
Publisher:
Release Date : 2018
A Multiscale Framework To Analyze Tricuspid Valve Biomechanics written by Vineet Sunny Thomas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Biomedical engineering categories.
The structure and composition of the extracellular matrix (ECM) fiber networks are closely tied to an overall biomechanical function of soft tissues such as heart valves. In particular, in the tricuspid valve (TV), due to various pathological conditions that require surgical interventions, the prevailing mechanical loading environment is modified. Such changes in the TV mechanical loading may induce alteration in the ECM structure and composition over time. Hence, there is a need to understand the long-term effects of such remodeling responses on the functioning capacity of the TV. This project framework clearly identifies the link among the ECM microstructural architecture, micro-scale biomechanics and the macro-scale mechanical responses of the TV leaflets. Such knowledge of multi-scale TV biomechanics is necessary to predict TV responses when subjected to modified mechanical loading environment as a result of a TV repair surgery or other prevailing valve pathologies. While previous studies have addressed the biomechanical behavior and complex geometry of the mitral valve and the aortic valve, the TV, which was once considered "the forgotten valve", has not been studied thoroughly. The TV, however, has received much attention in recent years due to efforts in increasing long-term survival of patients post TV surgeries. Computational models are effective tools to obtain insights regarding biomechanical changes in the valve following surgical procedures. However, currently the two available computational models of TV have been constructed based on a grossly simplified geometry and homogenous mechanical properties of the MV. Without a microstructurally and mechanically accurate model of the TV, conducting hypothesis-driven studies of valve pathologies, enhancing surgical procedures and improving treatment strategies are hindered. As such, we build a micro-structurally faithful model that includes contributions of cells, disorganized matrix, and organized fibers, which can predict the behavior of the TV leaflets.
Characterization Of Biomechanical Properties Of Mitral Valve Chordae Tendineae
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Author : Keping Zuo
language : en
Publisher:
Release Date : 2014
Characterization Of Biomechanical Properties Of Mitral Valve Chordae Tendineae written by Keping Zuo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Tricuspid Valve Reconstruction Using Porcine Extracellular Matrix
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Author : Diana M. Røpcke
language : en
Publisher:
Release Date : 2016
Tricuspid Valve Reconstruction Using Porcine Extracellular Matrix written by Diana M. Røpcke and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
Biomechanical Systems Technology A 4 Volume Set 1 Computational Methods
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Author : Cornelius T Leondes
language : en
Publisher: World Scientific
Release Date : 2007-12-05
Biomechanical Systems Technology A 4 Volume Set 1 Computational Methods written by Cornelius T Leondes and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-05 with Medical categories.
Because of rapid developments in computer technology and computational techniques, advances in a wide spectrum of technologies, coupled with cross-disciplinary pursuits between technology and its application to human body processes, the field of biomechanics continues to evolve. Many areas of significant progress include dynamics of musculoskeletal systems, mechanics of hard and soft tissues, mechanics of bone remodeling, mechanics of blood and air flow, flow-prosthesis interfaces, mechanics of impact, dynamics of man-machine interaction, and more. Thus, the great breadth and significance of the field in the international scene require a well integrated set of volumes to provide a complete coverage of the exciting subject of biomechanical systems technology. World-renowned contributors tackle the latest technologies in an in-depth and readable manner.