Blood Biochemistry
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Blood Biochemistry
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Author : N. J. Russell
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Blood Biochemistry written by N. J. Russell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
The idea for this book arose from an integrated Iecture course on the biochemistry of blood given to medical students in the second year of their pre-clinical studies. However, the material in that course has been expanded and it is intended that the book provide both the medical and non-medical reader with a concise and up-to-date account of the status of knowiedge of the biochemistry of blood. A glance at the chapter titles shows how wide a field this covers, including many of the growth areas in biochemistry. It is assumed that readers of the book will have a basic knowiedge of biochemistry. A functional approach is, adopted, and whenever possible the material is organised in terms of biochemical functions, although there are separate chapters on the white cell and the red cello Because of the clinical importance of analysing blood components and assaying enzymes in the diagnosis of disease, chapters are included on the separation, preparation and measurement of blood components.
Blood Biochemistry
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Author : N.J. Russell
language : en
Publisher:
Release Date : 1985
Blood Biochemistry written by N.J. Russell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with categories.
Blood Cell Biochemistry
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Author : Anthony D. Whetton
language : en
Publisher: Springer Science & Business Media
Release Date : 1996-08-31
Blood Cell Biochemistry written by Anthony D. Whetton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-08-31 with Medical categories.
Historically, the field of hematopoietic growth factor research began with the work of Carnot and Deflandre-in 1906 they suggested that the rate of erythropoiesis is regulated by a humoral factor found in the blood, namely, erythropoietin. From this comparatively early start, accelerating progress has been made in erythropoietin research, which demon strates the general trends in this field of study. Erythropoietin was purified to homogeneity by 1977 (from enormous quantities of urine from aplastic anemia patients). Subsequently, the gene for erythropoietin has been cloned (1985), and massive quantities of this growth factor have been produced for clinical trials (late 1980s onward). Erythropoietin has become established as a pharmaceutical product of great value in the treatment of a number of diseases, most notably chronic renal failure. Once the ligand had been cloned, interest turned to the erythropoietin receptor, which was cloned in 1989. Since then, structure/ function studies have been performed on receptor mutants, cellular signaling events down stream from the occupied receptor have been identified, and the specific producer cell types and molecular stimuli for erythropoietin production have been thoroughly investigated, as has the regulation of erythropoietin gene transcription. This schedule of events since the 1970s typifies that seen for a number of hematopoietic growth factors. Along the way, the hematopoietic growth factors have been recognized as members of the cytokine family of signaling molecules that are important in a number of different physiological and patholog ical situations (see below).
Chemistry And Biochemistry Of Oxygen Therapeutics
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Author : Andrea Mozzarelli
language : en
Publisher: John Wiley & Sons
Release Date : 2011-07-07
Chemistry And Biochemistry Of Oxygen Therapeutics written by Andrea Mozzarelli and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-07 with Science categories.
Human blood performs many important functions including defence against disease and transport of biomolecules, but perhaps the most important is to carry oxygen – the fundamental biochemical fuel - and other blood gases around the cardiovascular system. Traditional therapies for the impairment of this function, or the rapid replacement of lost blood, have centred around blood transfusions. However scientists are developing chemicals (oxygen therapeutics, or “blood substitutes”) which have the same oxygen-carrying capability as blood and can be used as replacements for blood transfusion or to treat diseases where oxygen transport is impaired. Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood links the underlying biochemical principles of the field with chemical and biotechnological innovations and pre-clinical development. The first part of the book deals with the chemistry, biochemistry, physiology and toxicity of oxygen, including chapters on hemoglobin reactivity and regulation; the major cellular and physiological control mechanisms of blood flow and oxygen delivery; hemoglobin and myoglobin; nitric oxide and oxygen; and the role of reactive oxygen and nitrogen species in ischemia/reperfusion Injury. The book then discusses medical needs for oxygen supply, including acute traumatic hemorrhage and anemia; diagnosis and treatment of haemorrhages in "non-surgical" patients; management of perioperative bleeding; oxygenation in the preterm neonate; ischemia normobaric and hyperbaric oxygen therapy for ischemic stroke and other neurological conditions; and transfusion therapy in β thalassemia and sickle cell disease Finally “old”and new strategies for oxygen supply are described. These include the political, administrative and logistic issues surrounding transfusion; conscientious objection in patient blood management; causes and consequences of red cell incompatibility; biochemistry of red blood cell storage; proteomic investigations on stored red blood cells; red blood cells from stem cells; the universal red blood cell; allosteric effectors of hemoglobin; hemoglobin-based oxygen carriers; oxygen delivery by natural and artificial oxygen carriers; cross-linked and polymerized hemoglobins as potential blood substitutes; design of novel pegylated hemoglobins as oxygen carrying plasma expanders; hb octamers by introduction of surface cysteines; hemoglobin-vesicles as a cellular type hemoglobin-based oxygen carrier; animal models and oxidative biomarkers to evaluate pre-clinical safety of extracellular hemoglobins; and academia – industry collaboration in blood substitute development. Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood is an essential reference for clinicians, haematologists, medicinal chemists, biochemists, molecular biologists, biotechnologists and blood substitute researchers.
Human Blood Groups
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Author : Helmut Schenkel-Brunner
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Human Blood Groups written by Helmut Schenkel-Brunner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
Although a few books covering primarily serological aspects of human blood groups are available, it became clear to me in the course of my research that no compendium of the non-serological aspects of human blood group systems exists. This book has been written to facilitate access to the vast number of publications scattered throughout the literature in both chemical and medical journals on the chemistry, biochemistry, and molecular biology of blood groups. It is designed as a concise survey for use by blood bankers and researchers in biochemistry, blood group serology, immunohaemotology, forensic medicine, population genetics, and anthropology; the text is supplemented by numerous illustrations and tables. This volume encompasses the entire field of blood group serology and provides a comprehensive survey of present knowledge in the field. The serological aspects have been kept to a minimum. I have emphasised the chemical, biochemical and molecular genetic basis of blood group specificity and given full consideration to molecular biology investigations, in particular to those on the structure of blood group genes and the structural basis of alleles and rare blood group variants. The book covers the latest developments in research and discusses literature up to the beginning of 1995.
Routine Blood Results Explained 3 E
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Author : Dr Andrew Blann
language : en
Publisher: M&K Update Ltd
Release Date : 2013
Routine Blood Results Explained 3 E written by Dr Andrew Blann and has been published by M&K Update Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
Now in its third edition, this essential handbook for nurses and allied health professionals gives clear, simple explanations of blood results, focusing on routinely requested investigations. There have been many changes since the second edition - from alterations in units (such as g/L for haemoglobin, rather than g/dL) to the merging of haematology with biochemistry, blood transfusion and immunology to form blood science. Accordingly, in this new edition there are more details of immunology, immunological diseases, and the blood tests involved.These changes reflect the new roles which nurses,
Blood Chemistry And Cbc Analysis
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Author : Dicken Weatherby
language : en
Publisher: Weatherby & Associates, LLC
Release Date : 2002
Blood Chemistry And Cbc Analysis written by Dicken Weatherby and has been published by Weatherby & Associates, LLC this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Blood categories.
Blood Science
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Author : Andrew Blann
language : en
Publisher: John Wiley & Sons
Release Date : 2022-12-27
Blood Science written by Andrew Blann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-27 with Science categories.
The second edition of the leading introduction to blood science, updated new illustrations and case studies Blood Science: Principles and Pathology integrates hematology and blood transfusion, clinical biochemistry, and immunology to provide a thorough introduction to this rapidly expanding discipline. Reflecting recent changes in education and training for healthcare scientists, this comprehensive textbook covers the analytical techniques used in blood science, the diagnosis and management of various blood disorders, and more. Fully revised, the second edition presents new case studies and high-quality images throughout, illustrating the practical skills and knowledge required by today's undergraduate students and practitioners. Detailed yet accessible chapters contain learning objectives and summaries, links to further readings and resources, and real-world case studies with easy-to-follow interpretations. Throughout the text, the authors highlight how laboratory data and clinical details are used to investigate patients with actual or suspected diseases in real-world scenarios Multi-disciplinary view merging biochemical, hematological, immunological, and genetical knowledge into a single discipline: Blood science Discusses advances in molecular genetics identifying mutations resulting in the occurrence of certain pathological conditions such as leukaemia Presents an expanded concluding chapter with detailed case reports that integrate biochemistry, immunology, and haematology which all contribute to the investigation of respective conditions. Explains the potentials for developing tests such as non-coding RNAs Offers further reading suggestions to dive even deeper in discussed subjects and concepts Designed to meet the needs of undergraduate students taking blood science modules in biomedical, biological, and healthcare science programs, Blood Science: Principles and Pathology, Second Edition is also an invaluable guide for new graduates entering the field as well as those training for professional qualifications or working with blood samples in laboratory-based environments.
Blood Coagulation
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Author : R.F.A. Zwaal
language : en
Publisher: Elsevier
Release Date : 1986-01-01
Blood Coagulation written by R.F.A. Zwaal and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-01-01 with Science categories.
This is the first book to give complete insight into the biochemistry of blood coagulation, and demonstrates how this field provides important contributions to fundamental biochemistry, such as enzyme kinetics, lipid-protein interactions, oxidative carboxylation, and cell receptors. The book will be of interest both to biochemists and molecular biologists who want to gain insight into the process of blood coagulation, as well as to those already working in the field of blood coagulation who desire to broaden their insight into its molecular aspects.
Biochemistry Of Blood In Health And Disease
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Author : Isaac Newton Kugelmass
language : en
Publisher:
Release Date : 1959
Biochemistry Of Blood In Health And Disease written by Isaac Newton Kugelmass and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1959 with Medical categories.