Catalyzing Inquiry At The Interface Of Computing And Biology
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Catalyzing Inquiry At The Interface Of Computing And Biology
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2006-01-01
Catalyzing Inquiry At The Interface Of Computing And Biology written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-01 with Science categories.
Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.
Catalyzing Inquiry At The Interface Of Computing And Biology
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Author : John C. Wooley and Herbert S. Lin
language : en
Publisher:
Release Date : 2005
Catalyzing Inquiry At The Interface Of Computing And Biology written by John C. Wooley and Herbert S. Lin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Bioinformatics categories.
Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.
Catalyzing Inquiry At The Interface Of Computing And Biology
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Author :
language : en
Publisher:
Release Date : 2005
Catalyzing Inquiry At The Interface Of Computing And Biology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
This study is the first comprehensive NRC study that suggests a high-level intellectual structure for Federal agencies for supporting work at the biology/computing interface. The report seeks to establish the intellectual legitimacy of a fundamentally cross-disciplinary collaboration between biologists and computer scientists. That is, while some universities are increasingly favorable to research at the intersection, life science researchers at other universities are strongly impeded in their efforts to collaborate. This report addresses these impediments and describes proven strategies for overcoming them. An important feature of the report is the use of well-documented examples that describe clearly to individuals not trained in computer science the value and usage of computing across the biological sciences, from genes and proteins to networks and pathways, from organelles to cells, and from individual organisms to populations and ecosystems. It is hoped that these examples will be useful to students in the life sciences to motivate (continued) study in computer science that will enable them to be more facile users of computing in their future biological studies.
Bioinformational Philosophy And Postdigital Knowledge Ecologies
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Author : Michael A. Peters
language : en
Publisher: Springer Nature
Release Date : 2022-04-22
Bioinformational Philosophy And Postdigital Knowledge Ecologies written by Michael A. Peters and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-22 with Education categories.
The book presents a cross-disciplinary overview of critical issues at the intersections of biology, information, and society. Based on theories of bioinformationalism, viral modernity, the postdigital condition, and others, this book explores two inter-related questions: Which new knowledge ecologies are emerging? Which philosophies and research approaches do they require? The book argues that the 20th century focus on machinery needs to be replaced, at least partially, by a focus on a better understanding of living systems and their interactions with technology at all scales – from viruses, through to human beings, to the Earth’s ecosystem. This change of direction cannot be made by a simple relocation of focus and/or funding from one discipline to another. In our age of the Anthropocene, (human and planetary) biology cannot be thought of without (digital) technology and society. Today’s curious bioinformational mix of blurred and messy relationships between physics and biology, old and new media, humanism and posthumanism, knowledge capitalism and bio-informational capitalism defines the postdigital condition and creates new knowledge ecologies. The book presents scholarly research defining new knowledge ecologies built upon emerging forms of scientific communication, big data deluge, and opacity of algorithmic operations. Many of these developments can be approached using the concept of viral modernity, which applies to viral technologies, codes and ecosystems in information, publishing, education, and emerging knowledge (journal) systems. It is within these overlapping theories and contexts, that this book explores new bioinformational philosophies and postdigital knowledge ecologies.
Globalization Biosecurity And The Future Of The Life Sciences
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2006-07-07
Globalization Biosecurity And The Future Of The Life Sciences written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-07 with Science categories.
Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways-leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise also means that many scientists and other individuals around the world are generating breakthroughs in the life sciences and related technologies. The risks posed by bioterrorism and the proliferation of biological weapons capabilities have increased concern about how the rapid advances in genetic engineering and biotechnology could enable the production of biological weapons with unique and unpredictable characteristics. Globalization, Biosecurity, and the Future of Life Sciences examines current trends and future objectives of research in public health, life sciences, and biomedical science that contain applications relevant to developments in biological weapons 5 to 10 years into the future and ways to anticipate, identify, and mitigate these dangers.
Computer Science
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Author :
language : en
Publisher: PediaPress
Release Date :
Computer Science written by and has been published by PediaPress this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Algebraic Biology
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Author : Hirokazu Anai
language : en
Publisher: Springer
Release Date : 2007-08-13
Algebraic Biology written by Hirokazu Anai and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-13 with Computers categories.
This volume constitutes the refereed proceedings of the Second International Conference on Algebraic Biology. The conference served as an interdisciplinary forum for the presentation of research on all aspects of the application of symbolic computation in biology, including computer algebra, computational logic, and related methods. Papers also examine solutions to problems in biology using symbolic methods.
Grid Computing In Life Sciences
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Author : Tin Wee Tan
language : en
Publisher: World Scientific
Release Date : 2006
Grid Computing In Life Sciences written by Tin Wee Tan and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Computers categories.
This is the second volume in the series of proceedings from the International Workshop on Life Science Grid. It represents the few, if not the only, dedicated proceedings volumes that gathers together the presentations of leaders in the emerging sub-discipline of grid computing for the life sciences. The volume covers the latest developments, trends and trajectories in life science grid computing from top names in bioinformatics and computational biology: A Konagaya; J C Wooley of the National Science Foundation (NSF) and DoE thought leader in supercomputing and life science computing, and one of the key people in the NSF CIBIO initiative; P Arzberger of PRAGMA fame; and R Sinnott of UK e-Science. Sample Chapter(s). Chapter 1: The Grid as a ba for Biomedical Knowledge Creation (155 KB). Contents: The Grid as a OC BaOCO for Biomedical Knowledge Creation (A Konagaya); Cyberinfrastructure for the Biological Sciences (CIBIO) (J C Wooley); Controlling the Chaos: Developing Post-Genomic Grid Infrastructures (R Sinnott & M Bayer); A Framework for Biological Analysis on the Grid (T Okumura et al.); An Architectural Design of Open Genome Services (R Umetsu et al.); Proteome Analysis Using iGAP in Gfarm (W W Li et al.); Large-Scale Simulation and Prediction of HLA-Epitope Complex Structures (A E H Png et al.); Process Integration for Bio-Manufacturing Grid (Z Q Shen et al.); and other papers. Readership: Practitioners of grid computing as applied to the life sciences, life scientists and biologists working on large computational solutions that require grid computing."
Grid Computing In The Life Science Proceedings Of The 2nd International Life Science Grid Workshop Lsgrid 2005
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Author : Tin Wee Tan
language : en
Publisher: World Scientific
Release Date : 2006-10-26
Grid Computing In The Life Science Proceedings Of The 2nd International Life Science Grid Workshop Lsgrid 2005 written by Tin Wee Tan and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-26 with Science categories.
This is the second volume in the series of proceedings from the International Workshop on Life Science Grid. It represents the few, if not the only, dedicated proceedings volumes that gathers together the presentations of leaders in the emerging sub-discipline of grid computing for the life sciences.The volume covers the latest developments, trends and trajectories in life science grid computing from top names in bioinformatics and computational biology: A Konagaya; J C Wooley of the National Science Foundation (NSF) and DoE thought leader in supercomputing and life science computing, and one of the key people in the NSF CIBIO initiative; P Arzberger of PRAGMA fame; and R Sinnott of UK e-Science.
Computer Aided Drug Design
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Author : Dev Bukhsh Singh
language : en
Publisher: Springer Nature
Release Date : 2020-10-09
Computer Aided Drug Design written by Dev Bukhsh Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-09 with Medical categories.
This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a range of computational applications, including three-dimensional modeling of protein structures, protein-ligand docking, and molecular dynamics simulation of protein-ligand complexes for identifying desirable drug candidates. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins, and summarizes the databases used to explore the essential properties of drugs, drug-like small molecules and their targets. In addition, the book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug candidates. Lastly, it reviews in silico tools that can facilitate vaccine design and discusses their limitations.