Cell Adhesion Molecules
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Adhesion Molecules
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Author : Victor R. Preedy
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Adhesion Molecules written by Victor R. Preedy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
This book covers the structure and classification of adhesion molecules in relation to signaling pathways and gene expression. It discusses immunohistochemical localization, neutrophil migration, and junctional, functional, and inflammatory adhesion molecules in pathologies such as leukocyte decompression sickness and ischemia reperfusion injury. H
Adhesion Molecules In Health And Disease
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Author : Paul
language : en
Publisher: CRC Press
Release Date : 1997-05-16
Adhesion Molecules In Health And Disease written by Paul and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-05-16 with Science categories.
Provides an overview of the structure, transcription regulation and binding characteristics of cellular adhesion molecules and their ligands in the maintenance of function, immunological reactions and inflammatory processes with organ systems. The text examines the role of adhesion molecules in biological processes such as morphogenesis, blood coagulation, tumour metastasis, bone tissue remodelling and transplant rejection.
Cell Adhesion Molecules
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Author : Martin E. Hemler
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cell Adhesion Molecules written by Martin E. Hemler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The Fourth Annual Pezcoller Symposium entitled Adhesion Molecules: Cellular Recognition Mechanisms was held in Rovereto, Italy, June 24-26, 1992 and was focussed on the detailed mechanisms whereby cells utilize certain integral membrane proteins to perceive their surrounding environment and interact with it. With timely presentations and stimulating discussions this Symposium addressed the genetics and biochemistry of adhesion molecules, the regulation of their functions and their role in cancer and the immune system. Emphasis was given to adhesion proteins in the integrin family because of the widespread distribution of this group of molecules and its important role in essentially all eukaryotic biological systems. The regulation of integrin genes and their expression are discussed in detail, as are specific aspects of the genetics of fibronectin. The molecular basis for the regulation of certain integrins, the function of these proteins in determining cell adhesion, and the consequences of this adhesion for the function of the cells involved are discussed. The role of certain integrins in stimulating signal transduction, the essential involvement of integrins in conditioning the function of T and NK cells function, the heterogeneity of integrins and its biological consequences, and the role of cell adhesion molecules in tumor cells invasion and metastases are all extensively analyzed. New information was presented on the role of CD44 and splice variants in normal differentiation and tumor progression.
Cell Adhesion
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Author : Mary C. Beckerle
language : en
Publisher: Oxford University Press, USA
Release Date : 2001
Cell Adhesion written by Mary C. Beckerle and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Cell adhesion categories.
Cell adhesion plays a central role in development and disease. Cell adhesion to particular ligands can affect cytoskeletal organization and cell polarity, cell proliferation, and gene expression. This book is divided into two parts. The first section provides a discussion of the structure and function of the seven major classes of cell adhesion molecules: integrins, cadherins, selectins, heparan sulfate proteoglycans, the immunoglobulin superfamily, the ADAMs proteins, and transmembrane protein tyrosine phosphatases. The roles of these cell adhesion proteins in important processes such as cell mediated immunity, development and disease are discussed. In the second section, the molecular organization and function of junctional complexes, regions of the cell surface that are highly specialized for cell adhesion, are examined. Junctional complexes are now known to mediate adhesive interactions and contribute to transmembrane signaling events that dramatically influence cell behaviour. The biochemical organization of the adhesive membranes and the molecular mechanisms by which they transmit information to the cell are addressed. Written by contributors among the most prominent in the field, Cell Adhesion covers a wide range of topics in a single volume. It will be a great resource for students, teachers and researchers.
Cellular Adhesion
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Author : Brian W. Metcalf
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Cellular Adhesion written by Brian W. Metcalf and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
The books in this acclaimed series provide integrated, critical surveys of topics of current interest to the pharmaceutical industry. Cellular Adhesion: Molecular Definition to Therapeutic Potential covers the molecular definition of adhesion molecule structure and function, the biological consequences of cellular adhesion, and the therapeutic potential of targeting adhesion molecules.
Adhesion Molecules Function And Inhibition
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Author : Klaus Ley
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-27
Adhesion Molecules Function And Inhibition written by Klaus Ley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-27 with Medical categories.
This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future approaches is also provided. The book is of interest to clinicians and scientists from immunology, physiology, cancer research, rheumatology, allergology, infectious diseases, gastroenterology, pulmonology and cardiology.
Cell Adhesion Molecules And Matrix Proteins
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Author : Shaker A. Mousa
language : en
Publisher:
Release Date : 1998
Cell Adhesion Molecules And Matrix Proteins written by Shaker A. Mousa and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Cell adhesion molecules categories.
Cell Adhesion Molecules In Cancer And Inflammation
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Author : Agamemnon A. Epenetos
language : en
Publisher: CRC Press
Release Date : 1995-06-01
Cell Adhesion Molecules In Cancer And Inflammation written by Agamemnon A. Epenetos and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-06-01 with Science categories.
Begins a series for clinicians, graduate students, and researchers in academia, regulatory agencies, or industry, offering monographs both on classes of adhesion molecules and on the function of such molecules in particular systems. Here the emphasis is on the clinical evaluation of these molecules, particularly as novel biochemical and genetic markers to define tumor differentiation based on functional and morphological assessment, and also their potential use as targets for biological therapy. Includes ten pages of color plates. Annotation copyright by Book News, Inc., Portland, OR
The Adhesive Interaction Of Cells
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Author : David Garrod
language : en
Publisher: Elsevier
Release Date : 1999-03-31
The Adhesive Interaction Of Cells written by David Garrod and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-03-31 with Science categories.
The aim of "The Adhesive Interaction of Cells" has been to assemble a series of reviews by leading international experts embracing many of the most important recent developments in this rapidly expanding field. The purpose of all biological research is to understand the form and function of living organisms and, by comprehending the normal, to find explanations and remedies for the abnormal and for disease conditions. The molecules involved in cell adhesion are of fundamental importance to the structure and function of all multicellular organisms. In this book, the contributors focus on the systems of vertebrates, especially mammals, since these are most relevant to human disease. It would have been equally possible to concentrate on developmental processes and adhesion in lower organisms. A major function of adhesion molecules is to bind cells to each other or to the extracellular matrix, but they are much more than "glue". Adhesions in animal tissues must be dynamic-forming, persisting, or declining in regulated fashion- to facilitate the mobility and turnover of tissue cells. Moreover, the majority of adhesion molecules are transmembrane molecules and thus provide links between the cells and their surroundings. This gives rise to another major function of adhesion molecules, the capacity to transduce signals across the hydrophobic barrier imposed by the plasma membrane. Such signal transduction is crucially important to many aspects of cellular function including the regulation of cell motility, gene expression, and differentiation. The work in this book progresses through four sections. Part I discusses the four major families of adhesion molecules themselves, the integrins (Green and Humphries), the cadherins (Stappert and Kemler), the selectins (Tedder et al.) and the immunoglobulin superfamily (Simmons); part 2 considers junctional complexes involved in cell interactions: focal adhesions and adherens junctions (Ben Ze'ev), desmosomes (Garrod et al.), and tight junctions (Citi and Cordenonsi). The signaling role of adhesion molecules is the focus of part 3, through integrins and the extracellular matrix (Edwards and Streuli), through platelet adhesion (Du and Ginsberg), and in the nervous system (Hemperley). In part 4, the aim is to show how adhesive phenomena contribute to important aspects of cell behavior and human health. Leukocyte trafficking (Haskard et al.), cancer metastasis (Marshall and Hart), cell migration (Paleck et al.), and implantation and placentation (Damsky et al.) are the topics considered in depth. The different sections are, of course, not mutually exclusive: it is both undesirable and impossible to separate structure from function when considering cell adhesion. Each chapter has its unique features, but some overlap is both invevitable and valuable since it provides different perspectives on closely related topics. We hope that the whole contributes a valuable and stimulating consideration of this important topic.
Molecular Biology Of Cell Adhesion Molecules
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Author : Michael A. Horton
language : en
Publisher:
Release Date : 1996-12-16
Molecular Biology Of Cell Adhesion Molecules written by Michael A. Horton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-12-16 with Medical categories.
This series is designed to bridge the gap between pure research in the biomedical sciences and its practical application in clinical medicine. The objective is to promote the understanding of the molecular basis of human physiology and disease, and new techniques for diagnosis and treatment. Primarily intended for graduate students of medicine, the books will also be of use to molecular biologists, biochemists, physiologists, pharmacologists and biotechnologists, as well as medical practitioners and technicians who seek to update their knowledge. There has been an explosion of interest in adhesion molecules in recent years and this has led to a greater understanding of cell behaviour in physiological and pathological situations. What has become increasingly clear is that data from enquiry-based research are eminently suited to be translated into applied clinical research. This timely and informative book introduces the topic of cell adhesion to the non-specialist and signifies areas where continuing research may yield results of clinical benefit. It will appeal to a wide audience including clinicians and postgraduate researchers in immunology and molecular biology and those involved in rheumatology, dermatology, gastroenterology, cardiology and haematology.