[PDF] Cellular Behaviors Regulating Tangential Migration Of Facial Branchiomotor Neurons In The Zebrafish Embryo - eBooks Review

Cellular Behaviors Regulating Tangential Migration Of Facial Branchiomotor Neurons In The Zebrafish Embryo


Cellular Behaviors Regulating Tangential Migration Of Facial Branchiomotor Neurons In The Zebrafish Embryo
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Cellular Behaviors Regulating Tangential Migration Of Facial Branchiomotor Neurons In The Zebrafish Embryo


Cellular Behaviors Regulating Tangential Migration Of Facial Branchiomotor Neurons In The Zebrafish Embryo
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Author : Anagha Sawant
language : en
Publisher:
Release Date : 2009

Cellular Behaviors Regulating Tangential Migration Of Facial Branchiomotor Neurons In The Zebrafish Embryo written by Anagha Sawant and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Electronic dissertations categories.


Development of the nervous system is characterized by intricate processes like neuronal migration, axon outgrowth and guidance and synaptic connections to their targets. These processes involve navigation of the migrating neuronsoraxonal growth cones through a complex extracellular environment in the neuron tube. Signals generated through cell-cell interactions between the migrating neurons, surrounding cells and the extracellular matrix likely play a major role in neuronal migration. We show here that transient axonal glycoprotein1 (TAG1) is necessary for the migration of the facial branchiomotor neurons (FBMNs) in the zebrafish hindbrain. We also show that TAG1 exhibits genetic interactions with the extracellular matrix protein laminin1 (LAMA1) and the transmembrane protein strabismus (STBM) to regulate FBMN migration. To gain insight into the underlying cellular mechanisms, we examined the dynamic cellular behaviors of GFP-expressing FBMNs in wild type and morphant embryos using time lapse microscopy. FBMNs in control and morphant embryos move at comparable speeds, but differ in directionality. Knockdown of any of the three genes leads to similar deficits in caudally directed migratory behavior without affecting mediolateral migratory behavior. Together, the genetic and behavioral analysis suggests strongly that TAG1, LAMA1 and STBM regulate the same cellular processes necessary for motor neuron migration.



Cellular Migration And Formation Of Neuronal Connections


Cellular Migration And Formation Of Neuronal Connections
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Author :
language : en
Publisher: Academic Press
Release Date : 2013-05-06

Cellular Migration And Formation Of Neuronal Connections written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-06 with Science categories.


The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity



Cells Advances In Research And Application 2011 Edition


Cells Advances In Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09

Cells Advances In Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Science categories.


Cells: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cells. The editors have built Cells: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cells in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cells: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.



Clinical Neuroembryology


Clinical Neuroembryology
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Author : Hans J. ten Donkelaar
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-09-07

Clinical Neuroembryology written by Hans J. ten Donkelaar and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-07 with Medical categories.


Progress in developmental neurobiology and advances in (neuro) genetics have been spectacular. The high resolution of modern imaging techniques applicable to developmental disorders of the human brain and spinal cord have created a novel insight into the developmental history of the central nervous system (CNS). This book provides a comprehensive overview of the development of the human CNS in the context of its many developmental disorders. It provides a unique combination of data from human embryology, animal research and developmental neuropathology, and there are more than 400 figures in over a hundred separate illustrations.



Prominin 1 Cd133 New Insights On Stem Cancer Stem Cell Biology


Prominin 1 Cd133 New Insights On Stem Cancer Stem Cell Biology
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Author : Denis Corbeil
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-19

Prominin 1 Cd133 New Insights On Stem Cancer Stem Cell Biology written by Denis Corbeil and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-19 with Medical categories.


​​​​​​​Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different models, as well as its use as a prognostic marker have emerged. Yet, beyond its use as a stem cell and cancer stem cell marker, prominin-1/CD133 displays unique biological features and appears of importance in other processes like for example in retinal biogenesis. Indeed, this five-transmembrane plasma membrane glycoprotein, which marks membrane protrusions is associated with several essential processes like cell polarity, asymmetric cell division and membrane remodeling. We propose to review current knowledge about this intriguing molecule and present pertinent information to determine the biological role of prominins and assess their importance in medicine and cancer research. The primary audience for this book is geared towards scientists and researchers with interest in cancer stem cells, stem cells, cell biology, neurobiology, and regenerative medicine.



Textbook Of Pediatric Neurosurgery


Textbook Of Pediatric Neurosurgery
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Author : Concezio Di Rocco
language : en
Publisher: Springer
Release Date : 2020-07-14

Textbook Of Pediatric Neurosurgery written by Concezio Di Rocco and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-14 with Medical categories.


This book documents the state of the art in pediatric neurosurgery with the intention of providing a comprehensive guide to the management of the full range of pediatric neurosurgical disorders that will aid in the delivery of optimal care. Detailed practical instruction, taking into account recent advances, is provided on the neurosurgical treatment of congenital brain malformations, cerebrovascular diseases, head injuries and spinal trauma, infections, functional disorders, congenital and developmental spinal disorders, and brain and spinal tumors. Pearls and pitfalls are highlighted, and attention drawn to the most useful tips and tricks. Information is also included on relevant related topics, including the principles of neuroimaging, the physiological responses of newborns, infants, and children to neurosurgical trauma, preoperative evaluation, anesthesiology and intensive care, and other forms of therapy. The authors are renowned experts in the field, and the text is supported by a wealth of high-quality images. Handbook of Pediatric Neurosurgery will be of value for neurosurgeons of all levels of experience, as well as for pediatricians, neuroradiologists, neuropathologists, and neuro-oncologists.



The Developing Brain


The Developing Brain
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Author : Michael Brown
language : en
Publisher: Oxford University Press, USA
Release Date : 2001

The Developing Brain written by Michael Brown and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.


'This is an inexpensive yet important book on neural development. It should be in neurology, neurosurgery, and bioscience libraries'. Doody's Electronic Journal, March 2003.An up to date and comprehensive overview of the developing nervous system, with particular emphasis on the vertebrate brain. Recent advances in the molecular genetic basis of developmental mechanisms are integrated with a synthesis of the classical literature to provide coverage of key events, from the first appearance of the nervous system in the early embryo to postnatal and later stages. The extensive reference list will also make it a useful source for teachers and researchers in the field.



Neuroanatomy Of The Oculomotor System


Neuroanatomy Of The Oculomotor System
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Author : Jean A. Büttner-Ennever
language : en
Publisher: Elsevier
Release Date : 2005-11-09

Neuroanatomy Of The Oculomotor System written by Jean A. Büttner-Ennever and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-09 with Science categories.


This volume in the Progress in Brain Research series features reviews on the functional neuroanatomy and connectivity of the brain areas involved in controlling eye movements. Oculomotor control of the eyes is now the subject of many research projects and advances in this field are relevant to understanding motor control in general.



Epigenetic Principles Of Evolution


Epigenetic Principles Of Evolution
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Author : Nelson R Cabej
language : en
Publisher: Elsevier
Release Date : 2011-11-22

Epigenetic Principles Of Evolution written by Nelson R Cabej and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-22 with Science categories.


This is the first and only book, so far, to deal with the causal basis of evolution from an epigenetic view. By revealing the epigenetic "user" of the "genetic toolkit", this book demonstrates the primacy of epigenetic mechanisms and epigenetic information in generating evolutionary novelties. The author convincingly supports his theory with a host of examples from the most varied fields of biology, by emphasizing changes in developmental pathways as the basic source of evolutionary change in metazoans. Original and thought provoking--a radically new theory that overcomes the present difficulties of the theory of evolution Is the first and only theory that uses epigenetic mechanisms and principles for explaining evolution of metazoans Takes an integrative approach and shows a wide range of learning



Evolution Of Nervous Systems


Evolution Of Nervous Systems
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Author : Jon H. Kaas
language : en
Publisher: Academic Press
Release Date : 2007

Evolution Of Nervous Systems written by Jon H. Kaas and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Nervous system categories.