Chagas Disease Diagnosis And Treatment

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Chagas Disease Diagnosis And Treatment

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Author : Malcolm Clark
language : en
Publisher: Murphy & Moore Publishing
Release Date : 2021-11-16

Chagas Disease Diagnosis And Treatment written by Malcolm Clark and has been published by Murphy & Moore Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-16 with Health & Fitness categories.

Chagas disease is a tropical disease which is caused by a parasite known as Trypanosoma cruzi. The symptoms do not manifest themselves in the early stages of the disease. Severe cases of this disease can result in heart diseases and digestive complications. Infection can be caused by a kissing bug's bite. It can spread from one person to another through organ transplantation, blood transfusion, vertical transmission and consumption of contaminated food. The diagnosis of Chagas disease is conducted by examining fresh anticoagulated blood under a microscope. The parasites can also be viewed directly by staining thin and thick blood smears with Giemsa. The treatment of this disease involves antiparasitic drugs and symptomatic treatment. This book is a compilation of chapters that discuss the most vital concepts and emerging trends related to the diagnosis and treatment of Chagas disease. It aims to shed light on some of the unexplored aspects of this disease and the recent researches in this field. This book will serve as a reference to a broad spectrum of readers.

Chagas Disease

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Author : Sandra R. Wall
language : en
Publisher:
Release Date : 2017

Chagas Disease written by Sandra R. Wall and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with HEALTH & FITNESS categories.

Chagas Disease

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Author : Sandra R. Wall
language : en
Publisher: Nova Biomedical Books
Release Date : 2017

Chagas Disease written by Sandra R. Wall and has been published by Nova Biomedical Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Chagas' disease categories.

The authors begin reviewing the characterization of American trypanosomiasis, or Chagas Disease, noting that although the disease has become less prevalent in recent decades, it is estimated that 8-10 million people are currently infected. Next, authors present a study wherein the dynamics of Trypanosoma cruzi infection (which causes Chagas disease) were mathematically modelled. This model assumed three clinical stages of the disease; acute, chronic indeterminate, and chronic with determinate pathology. Following this, cysteine proteases, ergosterol metabolic pathways, thiol-dependent mechanisms (trypanothione reductase), glycolytic pathways, trans-sialidase enzymes, the transport and metabolism of polyamines, and examples from literature are described in the context of therapeutic targets. The book goes on to discuss the history of nifurtimox and benznidazole, two drugs used in an effort combat Chagas disease. Additionally, the chapter addresses new therapies in clinical research to develop new treatments for Chagas' disease. In closing, the authors discuss the idea of targeting the cell cycle of T. cruzi in chemotherapy because the parasite undergoes several morphological changes to adapt to its vertebrate and invertebrate hosts.

Chagas Disease

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Author : Jaime Marcelo Altcheh
language : en
Publisher: Springer Nature
Release Date : 2019-09-09

Chagas Disease written by Jaime Marcelo Altcheh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-09 with Science categories.

Chagas disease is a potentially life threatening condition that was historically mainly endemic to Latin America. Over the last decade, however, the disease has spread to and is increasingly prevalent in other continents such as North America and Europe, with an estimated 7 million people infected worldwide. It is primarily transmitted by insect vectors that carry the parasite Trypanosoma cruzi, the disease agent. In areas where there is vector control and in non-endemic countries, it is mainly transmitted via congenital infection. Cardiac and gastrointestinal complications are common in untreated individuals. This book offers a comprehensive overview of Chagas disease, including its vectorial and congenital transmission, and molecular diagnosis, which is essential for screening, and developing and providing timely, effective anti-trypanosomal treatment. Written by experts working with infected patients on a daily basis, it discusses the pathogenesis of congenital, cardiac, gastrointestinal and oral Chagas disease, as well as its treatment and the pharmacological aspects of drug development in this area. Chapter "Chagas Disease Treatment Efficacy Biomarkers: Myths and Realities" is available open access under a via link.springer.com.

The New Improved Chagas Disease Cookbook

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Author : Dr Lillian Mildred
language : en
Publisher: Independently Published
Release Date : 2022-09-10

The New Improved Chagas Disease Cookbook written by Dr Lillian Mildred and has been published by Independently Published this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-10 with categories.

Chagas disease is a tropical disease which is caused by a parasite known as Trypanosoma cruzi. The symptoms do not manifest themselves in the early stages of the disease. Severe cases of this disease can result in heart diseases and digestive complications. Infection can be caused by a kissing bug's bite. It can spread from one person to another through organ transplantation, blood transfusion, vertical transmission and consumption of contaminated food. The diagnosis of Chagas disease is conducted by examining fresh anticoagulated blood under a microscope. The parasites can also be viewed directly by staining thin and thick blood smears with Giemsa. The treatment of this disease involves antiparasitic drugs and symptomatic treatment. This book is a compilation of chapters that discuss the most vital concepts and emerging trends related to the diagnosis and treatment of Chagas disease. It aims to shed light on some of the unexplored aspects of this disease and the recent researches in this field. This book will serve as a reference to a broad spectrum of readers.

Chagas Disease And Tuberculosis Diagnostic And Treatment Approaches

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Author : M. J. Munoz-Davila
language : en
Publisher: LAP Lambert Academic Publishing
Release Date : 2014-07-21

Chagas Disease And Tuberculosis Diagnostic And Treatment Approaches written by M. J. Munoz-Davila and has been published by LAP Lambert Academic Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-21 with categories.

In this book, new approaches to improve clinical diagnosis and treatment follow up of Chagas disease and tuberculosis are detailed. It summarizes investigation discoveries performed at references laboratories of both infectious diseases. Some of the main scientific publications published during those periods have been joined in this book, which is of the utmost interest for those experts working in these fields.

Chagas Disease

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Author : Alberto Novaes Ramos, Jr
language : en
Publisher: Mdpi AG
Release Date : 2021-08-19

Chagas Disease written by Alberto Novaes Ramos, Jr and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-19 with Medical categories.

Despite being described for the first time more than 110 years ago, Chagas disease (caused by the parasite Trypanosoma cruzi) persists as one of the most neglected tropical diseases. This persistent neglect of those affected by this disease is evidenced by the ongoing scientific evidence gaps, the difficulty of incorporating new diagnostic and treatment technologies into the market, and public health failures to ensure timely access to diagnosis and treatment associated with the development of consistent surveillance and control actions. As a result, there is a high burden of morbidity and mortality, and poor quality of life, poverty, stigma, and a fear of death persist for affected people, both in endemic areas in Latin America, and in non-endemic areas. This book spans a variety of disciplines and contributes significantly to reducing the gap in scientific knowledge on Chagas disease, towards achieving the Sustainable Development Goals by 2030.

Chagas Disease

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Author : María-Jesús Pinazo Delgado
language : en
Publisher: Springer Nature
Release Date : 2020-07-20

Chagas Disease written by María-Jesús Pinazo Delgado and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-20 with Medical categories.

This book provides a comprehensive resource on various aspects of the parasite Trypanosoma cruzi and the neglected tropical disease Chagas disease (American trypanosomiasis), the disorder resulting from infection with the parasite. Topics include the biological description and taxonomy of the parasite, epidemiology and transmission routes, laboratory techniques in use when working with the parasite, as well as diagnostic measures and treatment of Chagas disease. Furthermore, a chapter with life stories of people in contact with the disease in endemic as well as non-endemic countries is included. The book is therefore a valuable source for individuals engaged in basic research as well as patient care and health management related to American trypanosomiasis.

Chagas Disease

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Author :
language : en
Publisher: Academic Press
Release Date : 2011-08-03

Chagas Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-03 with Medical categories.

This thematic volume provides authoritative, up-to-date reviews addressing recent advances as well as an overview for the research and clinical communities on the endemic infection of Chagas disease. Lead researchers discuss epidemiology and control measures as well as various diagnosis techniques, treatments, and therapies currently being used. The text includes a history of Chagas disease and an outlook for the next century. Informs and updates on all the latest developments in the field Contributions from leading authorities and industry experts

American Trypanosomiasis

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Author : Jenny Telleria
language : en
Publisher: Elsevier
Release Date : 2010-09-03

American Trypanosomiasis written by Jenny Telleria and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-03 with Medical categories.

Chagas disease causes severe socioeconomic impact and a high medical cost in Latin America. WHO and the World Bank consider Chagas disease as the fourth most transmittable disease to have a major impact on public health in Latin America: 120 million persons are potentially exposed, 16 to 18 million of whom are presently infected, causing 45,000 to 50,000 deaths per year. It has been calculated that approximately 2.4 million potential working years are lost because of incapacity and mortality due to the disease, for an annual cost estimated at 20 billion Euros. American Trypanosomiasis provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease: The host: human and mammalian reservoirs The insect vectors: domestic and sylvatic vectors The causative parasite: Trypanosoma cruzi Informs and updates on all the latest developments in the field Contributions from leading authorities and industry experts