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Challenging The Limits Of The Human Life Span


Challenging The Limits Of The Human Life Span
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Challenging The Limits Of The Human Life Span


Challenging The Limits Of The Human Life Span
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Author : Wulf Droge
language : en
Publisher:
Release Date : 2010-07

Challenging The Limits Of The Human Life Span written by Wulf Droge and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07 with Health & Fitness categories.


Interventions that delay aging are expected to improve health. In the current US National Institute on Aging's Interventions Testing Program (ITP) the immunosuppressive drug rapamycin was found to increase the maximum life span in mice. These mice started receiving this treatment at an age corresponding to 60 years in humans. Rapamycin targets the same mechanism which was critically involved in the life span extension previously seen in certain mutants of worms flies and mice. The maximum life span was increased in some of these mutants by more than 250 percent, suggesting 1) that the maximum life span is limited by a common mechanism of death, and 2) that humans may possibly gain a few more decades beyond 120 years by interfering in this mechanism. As rapamycin has important adverse effects, this books looks into the underlying mechanisms and describes several natural interventions likely to decrease the rate of aging without using pharmacological drugs



Challenging The Limits Of The Human Life Span


Challenging The Limits Of The Human Life Span
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Author : Wulf Dröge
language : en
Publisher: iUniverse
Release Date : 2010-07-21

Challenging The Limits Of The Human Life Span written by Wulf Dröge and has been published by iUniverse this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-21 with Health & Fitness categories.


Interventions that delay aging are expected to improve health. In the current US National Institute on Agings Interventions Testing Program (ITP) the immunosuppressive drug rapamycin was found to increase the maximum life span in mice. These mice started receiving this treatment at an age corresponding to 60 years in humans. Rapamycin targets the same mechanism which was critically involved in the life span extension previously seen in certain mutants of worms flies and mice. The maximum life span was increased in some of these mutants by more than 250 percent, suggesting 1) that the maximum life span is limited by a common mechanism of death, and 2) that humans may possibly gain a few more decades beyond 120 years by interfering in this mechanism. As rapamycin has important adverse effects, this books looks into the underlying mechanisms and describes several natural interventions likely to decrease the rate of aging without using pharmacological drugs



The 100 Year Life


The 100 Year Life
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Author : Lynda Gratton
language : en
Publisher: Bloomsbury Publishing
Release Date : 2020-05-28

The 100 Year Life written by Lynda Gratton and has been published by Bloomsbury Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-28 with Self-Help categories.


What will your 100-year life look like? A new edition of the international bestseller, featuring a new preface 'Brilliant, timely, original, well written and utterly terrifying' Niall Ferguson Does the thought of working for 60 or 70 years fill you with dread? Or can you see the potential for a more stimulating future as a result of having so much extra time? Many of us have been raised on the traditional notion of a three-stage approach to our working lives: education, followed by work and then retirement. But this well-established pathway is already beginning to collapse – life expectancy is rising, final-salary pensions are vanishing, and increasing numbers of people are juggling multiple careers. Whether you are 18, 45 or 60, you will need to do things very differently from previous generations and learn to structure your life in completely new ways. The 100-Year Life is here to help. Drawing on the unique pairing of their experience in psychology and economics, Lynda Gratton and Andrew J. Scott offer a broad-ranging analysis as well as a raft of solutions, showing how to rethink your finances, your education, your career and your relationships and create a fulfilling 100-year life. · How can you fashion a career and life path that defines you and your values and creates a shifting balance between work and leisure? · What are the most effective ways of boosting your physical and mental health over a longer and more dynamic lifespan? · How can you make the most of your intangible assets – such as family and friends – as you build a productive, longer life? · In a multiple-stage life how can you learn to make the transitions that will be so crucial and experiment with new ways of living, working and learning? Shortlisted for the FT/McKinsey Business Book of the Year Award and featuring a new preface, The 100-Year Life is a wake-up call that describes what to expect and considers the choices and options that you will face. It is also fundamentally a call to action for individuals, politicians, firms and governments and offers the clearest demonstration that a 100-year life can be a wonderful and inspiring one.



Coping With Methuselah


Coping With Methuselah
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Author : Henry J. Aaron
language : en
Publisher:
Release Date : 2004

Coping With Methuselah written by Henry J. Aaron and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Science categories.


Many medical authorities predict that average life expectancy could well exceed 100 years by 2025, and could even rise to 120 by 2050.



Extra Life


Extra Life
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Author : Steven Johnson
language : en
Publisher: Penguin
Release Date : 2021-05-11

Extra Life written by Steven Johnson and has been published by Penguin this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-11 with Science categories.


“Offers a useful reminder of the role of modern science in fundamentally transforming all of our lives.” —President Barack Obama (on Twitter) “An important book.” —Steven Pinker, The New York Times Book Review The surprising and important story of how humans gained what amounts to an extra life, from the bestselling author of How We Got to Now and Where Good Ideas Come From In 1920, at the end of the last major pandemic, global life expectancy was just over forty years. Today, in many parts of the world, human beings can expect to live more than eighty years. As a species we have doubled our life expectancy in just one century. There are few measures of human progress more astonishing than this increased longevity. Extra Life is Steven Johnson’s attempt to understand where that progress came from, telling the epic story of one of humanity’s greatest achievements. How many of those extra years came from vaccines, or the decrease in famines, or seatbelts? What are the forces that now keep us alive longer? Behind each breakthrough lies an inspiring story of cooperative innovation, of brilliant thinkers bolstered by strong systems of public support and collaborative networks, and of dedicated activists fighting for meaningful reform. But for all its focus on positive change, this book is also a reminder that meaningful gaps in life expectancy still exist, and that new threats loom on the horizon, as the COVID-19 pandemic has made clear. How do we avoid decreases in life expectancy as our public health systems face unprecedented challenges? What current technologies or interventions that could reduce the impact of future crises are we somehow ignoring? A study in how meaningful change happens in society, Extra Life celebrates the enduring power of common goals and public resources, and the heroes of public health and medicine too often ignored in popular accounts of our history. This is the sweeping story of a revolution with immense public and personal consequences: the doubling of the human life span.



Images Of Aging


Images Of Aging
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Author : Mike Featherstone
language : en
Publisher: Routledge
Release Date : 2003-09-02

Images Of Aging written by Mike Featherstone and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Education categories.


The contributors in this book discuss images of aging which have come to circulate in the advanced industrial societies today. They address such themes as gender images of aging, images of health, illness and death.



Handbook Of Life Span Development


Handbook Of Life Span Development
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Author : Karen L. Fingerman
language : en
Publisher: Springer Publishing Company
Release Date : 2011

Handbook Of Life Span Development written by Karen L. Fingerman and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.


Print+CourseSmart



Advances In Geroscience


Advances In Geroscience
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Author : Felipe Sierra
language : en
Publisher: Springer
Release Date : 2015-11-10

Advances In Geroscience written by Felipe Sierra and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-10 with Medical categories.


This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’ The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer’s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.



Aging


Aging
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Author : Stuart Jay Olshansky
language : en
Publisher:
Release Date : 2016

Aging written by Stuart Jay Olshansky and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with MEDICAL categories.


"Aging affects us all and is characterized not only by increasing frailty but by increased susceptibility to conditions such as Alzheimer's, cardiovascular disease, and cancer. We are gaining an increasing understanding of the molecular mechanisms underlying aging, however, and uncovering clues to how life may be prolonged. This book examines the biological basis of aging and research into strategies that may extend lifespan"--



Supercentenarians


Supercentenarians
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Author : Heiner Maier
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-05-17

Supercentenarians written by Heiner Maier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-17 with Social Science categories.


Does human mortality after age 110 continue to rise, level off, or start to decline? This book describes a concerted, international research effort undertaken with the goal of establishing a database that allows the best possible description of the mortality trajectory beyond the age of 110. The International Database on Longevity (IDL) is the result of this ongoing effort. The IDL contains exhaustive information on validated cases of supercentenarians (people 110 years and older) and allows unbiased estimates of mortality after age 110. The main finding is remarkable: human mortality after age 110 is flat at a probability of death of 50% per year. The sixteen chapters of this book discuss age validation of exceptional longevity, data on supercentenarians in a series of countries, structure and contents of the IDL, and statistical analysis of human mortality after age 110. Several chapters include short accounts of specific supercentenarians that add life to demographic research.