Chemistry And Biological Activities Of Ivermectin
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Chemistry And Biological Activities Of Ivermectin
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Author : Rashid Ali
language : en
Publisher: John Wiley & Sons
Release Date : 2023-10-17
Chemistry And Biological Activities Of Ivermectin written by Rashid Ali and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-17 with Science categories.
CHEMISTRY AND BIOLOGICAL ACTIVITIES OF IVERMECTIN The book focuses on the biological activities of ivermectin as well as the significant global utility of IVM since it was first used about 35 years ago. Ivermectin (IVM) is a “wonder drug” containing a 16-membered macrocyclic lactone ring system in its structure and derived from the family of avermectins. It was isolated by the fermentation of the soil microorganism Streptomyces avermitilis by Satoshi Omura in 1960 and studied by William C. Campbell in 1981, which allowed for its treatment of onchocerciasis (River Blindness) in Africa. Both scientists subsequently received the 2015 Nobel Prize in Physiology or Medicine. It was approved by the FDA in 1997 for the treatment of Strongyloidiasis and crusted scabies in AIDS patients. After that, IVM has attracted the tremendous attention of the scientific community and has been used for diverse purposes, including as an inhibitor of the causative virus (SARS-CoV-2). The chief purpose of this volume is to focus on the chemistry and biological activities of ivermectin. The chapters have been arranged in a systematic manner, starting from the historical background and synthesis of IVM to the pharmacological and environmental aspects, followed by diverse applications. Although the usage of ivermectin for the treatment of COVID-19 remains under investigation and controversial, one of the chapters is dedicated to its use. The anti-parasitic, anti-malarial, anti-cancer, and anti-inflammatory activities of IVM are discussed in detail. The anthelminthic and insecticidal roles of IVM are briefly described and there are several cases of IVM in dermatology. Audience Researchers, scientists, and postgraduate students working in the fields of organic synthesis, medicinal chemistry, medical science, pharmacy, biotechnology and biomedical sciences.
Ivermectin And Abamectin
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Author : William C. Campbell
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Ivermectin And Abamectin written by William C. Campbell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Ivermectin and abamectin, members of the avermectin family of compounds, were introduced to the market in the 1980's as a veterinary antiparasitic drug and agricultural pesticide, respectively. Their acceptance and commercial success have been remarkable; both are highly effective and in worldwide use. The efficacy of ivermectin in river blindness has expanded the interest in its use in human medicine. In response to the intense scientific and industrial interest in ivermectin and abamectin and the likelihood that they will be forerunners of an expanding family of drugs, this comprehensive monograph satisfies the need for a review and synthesis of current knowledge about the use of these substances in crop protection as well as in cattle, sheep, swine, horses, dogs, cats, birds, fish, reptiles, and in man. This overview presents chemical, biochemical, and microbiological data, as well as pharmacological, safety, and environmental aspects and covers practical use of the compounds as antiparasitic and pesticide agents, as well as the available safety data that have emerged from the clinical experience with human applications.
Macrolide Antibiotics
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Author : Satoshi Omura
language : en
Publisher: Academic Press
Release Date : 2002-06-10
Macrolide Antibiotics written by Satoshi Omura and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-06-10 with Medical categories.
Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifungal research and treament.
The Alkaloids
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Author :
language : en
Publisher: Elsevier
Release Date : 2003-10-13
The Alkaloids written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-10-13 with Science categories.
This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Up-to-date reviews on a large and very important group of natural products from both a chemical and biological perspective Comprehensive dynamic reviews written by the leading authors in the respective fields Broader coverage than before on the biological aspects
Chemistry Of Biologically Potent Natural Products And Synthetic Compounds
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Author : Shahid Ul-Islam
language : en
Publisher: John Wiley & Sons
Release Date : 2021-06-29
Chemistry Of Biologically Potent Natural Products And Synthetic Compounds written by Shahid Ul-Islam and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-29 with Science categories.
In view of their promising biological and pharmaceutical activities, natural product inspired and heterocyclic compounds have recently gained a reputation in the field of medicinal chemistry. Over the past decades, intensive research efforts have been ongoing to understand the synthesis, biochemistry and engineering involved in their preparation and action mechanisms. Several novel natural product derivatives, heterocyclic and other synthetic compounds, have been reported to have shown interesting biological activities including anticancer, antimicrobial, anti-inflammatory, anti-glycemic, anti-allergy and antiviral etc. Chemistry of Biologically Potent Natural Products and Synthetic Compounds provides up-to-date information on new developments and most recent medicinal applications of the natural products and derivatives, as well as the chemistry and synthesis of heterocyclic and other related compounds.
Polysaccharides In Medicinal Applications
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Author : Severian Dumitriu
language : en
Publisher: Routledge
Release Date : 2017-10-19
Polysaccharides In Medicinal Applications written by Severian Dumitriu and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-19 with Science categories.
Integrates the latest advances in polysaccharide chemistry and structure analysis, with the practical applications of polysaccharides in medicine and pharmacy, highlighting the role of glycoconjugates in basic biological processes and immunology. It also presents recent developments in glycobiology and glycopathology. The work covers bacterial, fungal and cell-wall polysaccharides, microbial and bacterial exopolysaccharides, industrial gums, the biosynthesis of bacterial polysaccharides, and the production of microbial polysaccharides.
The Biology Chemistry Interface
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Author : Raymond Cooper
language : en
Publisher: CRC Press
Release Date : 1999-07-22
The Biology Chemistry Interface written by Raymond Cooper and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-07-22 with Science categories.
A tribute to the pioneering scientific work of Professor Koji Nakanishi, whose studies of natural products have effaced some of the conventional boundaries between biology and chemistry. It discusses an array of chromatographic separation methods and determination of structures on a microscale, analyzes bioassay-directed fractionation and other means of isolating biologically active compounds from plants and other sources, covers vital enzymes isolated from marine organisms such as algae, and more.
Advances In Metallodrugs
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Author : Shahid Ul-Islam
language : en
Publisher: John Wiley & Sons
Release Date : 2020-07-08
Advances In Metallodrugs written by Shahid Ul-Islam and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-08 with Science categories.
This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering.
Molecular Diversity Of Environmental Prokaryotes
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Author : Thiago Bruce Rodrigues
language : en
Publisher: CRC Press
Release Date : 2016-08-19
Molecular Diversity Of Environmental Prokaryotes written by Thiago Bruce Rodrigues and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-19 with Medical categories.
This book correlates the vast genetic diversity associated with environmental samples and still underexploited potential for the development of biotechnology products. The book points out the potential of different types of environmental samples. It presents the main characteristics of microbial diversity, the main approaches used for molecular characterization of the diversity, and practical examples of application of the exploration of the microbial diversity. It presents a not-yet-explored structure for discussing the main topics related to molecular biology of environmental prokaryotes and their biotechnological applications.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1997
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medicine categories.