Chiral Chromatography
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Chiral Chromatography
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Author : Thomas E. Beesley
language : en
Publisher: John Wiley & Sons
Release Date : 1999-01-26
Chiral Chromatography written by Thomas E. Beesley and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-01-26 with Science categories.
Eine Ergänzung anderer, in der Reihe Separation Sciences bereits erschienener Titel. Viel Theorie und zahlreiche Anwendungsbeispiele für die Praxis der chiralen HPLC- und GC-Trennung machen dieses top-aktuelle Buch zu einer unverzichtbaren Informationsquelle für jeden Neueinsteiger auf diesem Gebiet. (11/98)
Chiral Separation Methods For Pharmaceutical And Biotechnological Products
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Author : Satinder Ahuja
language : en
Publisher: John Wiley & Sons
Release Date : 2011-03-31
Chiral Separation Methods For Pharmaceutical And Biotechnological Products written by Satinder Ahuja and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-31 with Science categories.
Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.
Chiral Separations
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Author : D. Stevenson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chiral Separations written by D. Stevenson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This volume represents the proceedings of a two-day international meeting on chiral chromatography held at the University of Surrey between 3-4 September 1987. The meeting was jointly organized by the Chromatographic SOCiety and the Robens Institute of the University of Surrey in response to the burgeoning interest in this rapid maturing field of chromatography. Nowhere is this interest more evident than in the agrochemical and pharmaceutical industries where the implications of different pharmacological and toxicological activity for the individual enantiomers present in a racemic drug ol" insecticide is an increasing area of concern. Developments in the area of chiral separations are at last beginning to provide SCientists with the necessary tools to study how animals and man handle racemates and relate their obseIVations to the obseIVed biological effects of these substances. The development of robust and Simple methods for the separation of enantiomers will therefore have a profound Impact on safety evaluation and drug design. The meeting proved to be very successful. with over 160 delegates from thirteen countries in Europe and America present to learn from the experiences of experts in the field of chiral chromatography and to hear about the latest developments. Hopefully. in future symposia on chiral separations at the University of Surrey.
Recent Advances In Chiral Separations
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Author : D. Stevenson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Recent Advances In Chiral Separations written by D. Stevenson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This volume represents the proceedings of the second international meeting on chiral separations held at the University of Surrey between the 12th and 15th of September 1989. Like the preceding meeting, it was jointly organised by the Chromatographic Society and the Robens Institute of the University of Surrey in response to the continued interest in this area of separation science. Of particular interest to the organisers was the very clear change in the nature of the delegates attending this second symposium as compared with the first. At the previous meeting the majority of the delegates were composed of chromatographers with problems in the area of chiral separations who were keen to learn as much as possible about these techniques from the handful of recognised experts in this area. In this second symposium the divide between expert and novice was much less apparent, with the latter providing many interesting and useful contributions to the scientific programme in termt; of both oral and poster presentations.
Chiral Liquid Chromatography
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Author : w Lough
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chiral Liquid Chromatography written by w Lough and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
While working as a chromatographer in the pharmaceutical industry, it became apparent to the editor that there was a pressing need for a comprehensive reference text for analysts working on the resolution of enantiomers by liquid chromatography (LC). This need arises from the fact that, whereas previously it was very difficult to determine enantiomers by direct means, there is now a wide choice of direct LC methods. At the same time, regulatory authorities have been changing their attitudes towards the administration of pharmaceuticals as racemates, partly because it is now possible to study the individual enantiomers. Clearly this abundance of new information needs to be rationalized. More importantly, the chiral LC systems which are commercially available or readily accessible to the practising chromatographer needed to be reviewed and, to a much greater extent than in existing reviews or books, discussed in terms of their practical application. Accordingly this book is very much orientated towards the practical aspects of these commercially available and readily accessible chiral LC systems. To this end, it is written for practising chromatographers by a team of practising, experienced chromatographers who have spent many years tackling the problems presented by resolving enantiomers by LC. The practical aspects of common chiral LC systems cannot be fully understood if discussed in isolation.
Chiral Separations By Liquid Chromatography And Related Technologies
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Author : Hassan Y. Aboul-Enein
language : en
Publisher: CRC Press
Release Date : 2003-06-03
Chiral Separations By Liquid Chromatography And Related Technologies written by Hassan Y. Aboul-Enein and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-03 with Science categories.
Unique in its systematic and detailed description of the various types, structures, and properties of chiral stationary phases (CSPs) and their preparation, application, and future scope, this volume highlights an assortment of liquid chromatographic approaches, including sub- and super-critical fluid chromatography, capillary electrochromatography
Chromatographic Enantioseparation
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Author : Stig G. Allenmark
language : en
Publisher: Ellis Horwood
Release Date : 1988
Chromatographic Enantioseparation written by Stig G. Allenmark and has been published by Ellis Horwood this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Science categories.
Allenmark (microbiological chemistry, U. of Gothenburg) gives a thorough treatment of chiral chromatography, covering basic theory, methods (particularly stationary phase design), and applications. Treatment is self-contatined; early chapters explain principles, incorporating background material on organic stereochemistry; later ones cover instrumentation, preparation, synthesis, and analysis. Includes in-depth coverage of liquid chromatographic methods and discussion of industrial uses for large-scale preparative resolutions, including column sample capacity, chromatographic reproducability, and automatic operation. Acidic paper. Annotation copyrighted by Book News, Inc., Portland, OR
Chiral Analysis
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Author : P.L. Polavarapu
language : en
Publisher: Elsevier
Release Date : 2018-05-30
Chiral Analysis written by P.L. Polavarapu and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-30 with Science categories.
Chiral Analysis: Advances in Spectroscopy, Chromatography and Emerging Methods, Second Edition covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals, including chemistry graduate students, analytical chemists, organic chemists, professionals in the pharmaceutical industry, and others with an interest in chirality and chiral analysis. This thoroughly revised second edition covers several new, important areas of chiral analysis that have emerged since the first edition. Three of the new methods provide higher sensitivity than can be realized with the current methods and are expected to become mainstream applications: cavity based methods offer vastly higher sensitivity than conventional polarimetric methods, microwave chiral detection provides unsurpassed sensitivity for identifying diastereomers, and the rotating electric field method offers a competing new approach for the separation of enantiomers. Another topic, chirality in extraterrestrial life, has not been discussed in any other book and is important for understanding the origin of life. Offers the only book to cover both spectroscopic and separation methods in a single volume Provides an up-to-date and detailed review of the various techniques available, including new techniques that have emerged since the first edition Includes contributions from a range of leading experts in the field, now edited by award-winning chirality researcher Prasad Polavarapu
Preparative Enantioselective Chromatography
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Author : Geoffrey B. Cox
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
Preparative Enantioselective Chromatography written by Geoffrey B. Cox and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Science categories.
The development of chiral liquid chromatography, facilitating thestraightforward separation of enantiomers, was a significantadvance in chromatography, leading to widespread application inanalytical chemistry. Application in preparative chromatography hasbeen less rapid, but with the development of single enantiomerpharmaceuticals its use is increasingly common in chemicalsynthesis at laboratory, pilot plant and even full productionscale. Brings non-experts up to speed quickly and comprehensively,facilitating the rapid development of effective separations ofenantiomeric mixtures on a range of process scales Presents case studies drawn from within the pharmaceuticalindustry to clearly illustrate the utility and value of preparativescale enantioselective chromatography in chemical research,development and production Key reference source and entry to the literature so the readerdoes not have to engage in expensive and time consuming literaturesearching
Chiral Separations By Chromatography
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Author : Satinder Ahuja
language : en
Publisher:
Release Date : 2000
Chiral Separations By Chromatography written by Satinder Ahuja and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Language Arts & Disciplines categories.
A large number of examples are given that will assist in the selection of a method, including thin-layer chromatography, capillary electrophoresis and membrane separations." "This book will be a reliable guide for those just starting out in pharmaceutical and related industries, as well as those with experience in the field."--Jacket.