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Chloride Channels


Chloride Channels
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Chloride Channels


Chloride Channels
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Author :
language : en
Publisher: Academic Press
Release Date : 1994-09-15

Chloride Channels written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-09-15 with Science categories.


The amount of new information on the molecular biology of chloride channels has grown tremendously in recent years. This large amount of information gives some unique and, in some instances, surprising insights into the function and structure of chloride channels which are present in every cell. This volume contains a series of in-depth reviews of chloride channel physiology, biophysics, and molecular biology. The reviews cover chloride channels found in the plasma membrane as well as in organelles of both plant and animal cells. Key Features * Discusses CFTR, the cystic fibrosis transmembrane regulator, which is responsible for CF and the CIC-family of chloride channels responsible for myotonia congenita * In-depth reviews of chloride channel physiology, biophysics, and molecular biology * Reviews chloride channels found in the plasma membrane and in organelles of both plant and animal cells



Calcium Activated Chloride Channels


Calcium Activated Chloride Channels
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Author : Catherine Mary Fuller
language : en
Publisher: Gulf Professional Publishing
Release Date : 2002-09-19

Calcium Activated Chloride Channels written by Catherine Mary Fuller and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-19 with Science categories.


This volume draws together studies on the diverse group of calcium-activated chloride channels (CaCCS) in one comprehensive format. The characteristics of CaCCs identified in a number of different systems are described by experts in the field. Channels discussed include those described in cardiac, neuronal, endothelial and epithelial systems, in addition to sections on the CaCC of Xenopus Oocytes and the newly identified family of CLCA proteins. Key Features * Includes description of CaCCs in excitable and non-excitable tissues * Reviews identification and cloning of the CLCA protein family * Contains section on CaCCs in Xenopus Oocytes



Chloride Channels And Carriers In Nerve Muscle And Glial Cells


Chloride Channels And Carriers In Nerve Muscle And Glial Cells
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Author : F.J. Alvarez-Leefmans
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Chloride Channels And Carriers In Nerve Muscle And Glial Cells written by F.J. Alvarez-Leefmans and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.


This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability(? CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener alized and virtually all cells were thought to have a very high P Cl and a ther modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks.



Chloride Channels Advances In Research And Application 2011 Edition


Chloride Channels Advances In Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09

Chloride Channels Advances In Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Science categories.


Chloride Channels: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Chloride Channels in a concise format. The editors have built Chloride Channels: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chloride Channels in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Chloride Channels: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.



Physiology And Pathology Of Chloride Transporters And Channels In The Nervous System


Physiology And Pathology Of Chloride Transporters And Channels In The Nervous System
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Author : F. Javier Alvarez-Leefmans
language : en
Publisher: Academic Press
Release Date : 2009-08-22

Physiology And Pathology Of Chloride Transporters And Channels In The Nervous System written by F. Javier Alvarez-Leefmans and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-22 with Medical categories.


The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium across the plasma membrane of most cells. Research carried out during the last couple of decades has led to a dramatic change in this simplistic view. We now know that most animal cells, neurons included, exhibit a non-equilibrium distribution of Cl- across their plasma membranes. Over the last 10 to 15 years, with the growth of molecular biology and the advent of new optical methods, an enormous amount of exciting new information has become available on the molecular structure and function of Cl- channels and carriers. In nerve cells, Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control. Disruption of Cl- homeostasis in neurons underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation. This book is about how chloride ions are regulated and how they cross the plasma membrane of neurons. It spans from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases. The first comprehensive book on the structure, molecular biology, cell physiology, and role in diseases of chloride transporters / channels in the nervous system in almost 20 years Chloride is the most abundant free anion in animal cells. THis book summarizes and integrates for the first time the important research of the past two decades that has shown that Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control The first book that systematically discusses the result of disruption of Cl- homeostasis in neurons which underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation Spanning topics from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases Involves all of the leading researchers in the field Includes an extensive introductory section that covers basic thermodynamic and kinetics aspects of Cl- transport, as well as current methods for studying Cl- regulation, spanning from fluorescent dyes in single cells to knock-out models to make the book available for a growing population of graduate students and postdocs entering the field



Chloride Movements Across Cellular Membranes


Chloride Movements Across Cellular Membranes
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Author :
language : en
Publisher: Elsevier
Release Date : 2011-09-22

Chloride Movements Across Cellular Membranes written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-22 with Science categories.


All living cells are surrounded by a lipidic membrane that isolates them from the often harsh environment. However, to take up nutrients, to excrete waste, and to communicate among each other, Nature has invented an incredibly diverse set of transmembrane transport proteins. Specialized transporters exist to shuttle electrically charged ions, positive cations like sodium or negative anions like chloride, across the membrane. In the recent years, tremendous progress has been made in the field of chloride transport. The present book presents the state of the art of this rapidly expanding and interest-gaining field of membrane transport. It is addressed at a broad medically, physiologically, biologically, and biophysically interested readership. Describes the state-of-the-art in anion transport research Written by leaders in the field Presents a timely discussion of this rapidly emerging and expanding field



Chloride Channels And Their Modulation By Neurotransmitters And Drugs


Chloride Channels And Their Modulation By Neurotransmitters And Drugs
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Author : Giovanni Biggio
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1988

Chloride Channels And Their Modulation By Neurotransmitters And Drugs written by Giovanni Biggio and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.




Chloride Channels Advances In Research And Application 2012 Edition


Chloride Channels Advances In Research And Application 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26

Chloride Channels Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Science categories.


Chloride Channels—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Chloride Channels in a concise format. The editors have built Chloride Channels—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chloride Channels in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Chloride Channels—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.



Progress In Chloride Channels


Progress In Chloride Channels
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Author :
language : en
Publisher:
Release Date :

Progress In Chloride Channels written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Molecular Mechanism Of Common Gating In Clc 0 Chloride Channel


Molecular Mechanism Of Common Gating In Clc 0 Chloride Channel
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Author : Ekaterina Alekseevna Bykova
language : en
Publisher:
Release Date : 2008

Molecular Mechanism Of Common Gating In Clc 0 Chloride Channel written by Ekaterina Alekseevna Bykova and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.