Coa
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Regulation Of Hmg Coa Reductase
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Author : Benjamin Preiss
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Regulation Of Hmg Coa Reductase written by Benjamin Preiss and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Nature categories.
Regulation of HMG-CoA Reductase is a nine-chapter text that focuses on the research developments in the regulation of HMG-CoA reductase enzyme and cholesterol biosynthesis. This book deals first with the role of cholesterol in the regulation of its own biosynthesis and the work involving compactin and related competitive inhibitors of HMG-CoA reductase. The subsequent chapters examine the reversible phosphorylation of HMG-CoA reductase in hormonal and other short-term physiological changes and the structure and properties of the enzyme, including evidence for modulation of enzyme activity and structure unrelated to phosphorylation. These topics are followed by discussions on the regulation of reductase in the biosynthesis of ubiquinone, dolichols, and isopentenyl-tRNA and the regulation of reductase activity in extrahepatic tissues. This text further explores the contributions made through the use of cultured cells and their genetic manipulation, with emphasis on the great potential of this approach. The concluding chapters address the status of the low-density lipoprotein pathway and related mechanisms. These chapters also consider the regulation of human hepatic HMG-CoA reductase and the special problems inherent in work with human tissues. Enzyme scientists and researchers and graduate students will find this book invaluable.
Hmg Coa Reductase Inhibitors
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Author : Gerd Schmitz
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06
Hmg Coa Reductase Inhibitors written by Gerd Schmitz and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
HMG-CoA reductase inhibitors (statins) are established drugs for the treatment of hypercholesterolemia. Furthermore, they induce regression of vascular atherosclerosis as well as reduction of cardiovascular-related morbidity and death in patients with and without coronary artery disease. This book deals with statins which have substantially altered the approach to therapy of atherosclerosis and its sequelae. Emphasis is placed on the scientific background to the discoveries and the development of the therapy, including an overview of the current state of knowledge of the drugs. Clinical data are reviewed extensively. This book not only provides the reader with valuable information but also stimulates further research into the pathogenesis of atherosclerosis and the mechanisms behind the action of effective statins. It sets the stage for creative thinking among scientists of many disciplines for the accomplishment of our ultimate goals in treating atherosclerosis and its sequelae. This topical volume...
Stearoyl Coa Desaturase Genes In Lipid Metabolism
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Author : James M. Ntambi, Ph.D.
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-08-15
Stearoyl Coa Desaturase Genes In Lipid Metabolism written by James M. Ntambi, Ph.D. and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-15 with Medical categories.
Obesity and diabetes develop as a complex result of genetic, metabolic and environmental factors and are characterized by increased lipogenesis and lipid accumulation in many tissues. Stearoyl-CoA desaturase (SCD) genes are a critical regulator of lipogenesis and catalyzes the synthesis of monounsaturated fatty acids (MUFA), mainly oleoyl- (18:1n9) and palmitoleoyl-CoA (16:1n7). These MUFAs are the major fatty acid substrates for the synthesis of triglycerides, cholesterol esters, wax esters and membrane phospholipids. There are 4 SCD isoforms (SCD1-4) in mice and two (hSCD1 and hSCD5) expressed in humans. At first glance, stearoyl-CoA desaturase enzyme would be considered a housekeeping enzyme because it synthesizes oleate a well-known fatty acid that is abundant in many dietary sources. However numerous studies have shown that SCD is a very highly regulated enzyme that features in so many physiological processes ranging from fat differentiation, carbohydrate and fat metabolism, inflammation and cancer. The editor’s studies using stearoyl-CoA desaturase knockout (SCD1-/-) mice and studies of other investigators using pharmacological approaches to reduce SCD1 expression in mouse tissues have all established that the expression of SCD1 gene isoform represents a key step in partitioning of lipids between storage and oxidation. High SCD expression favors fat storage leading to obesity while reduced SCD expression favors fat burning and leanness. Although these studies clearly illustrated that SCD1 expression is involved in the development of obesity and insulin resistance, questions remain in the elucidation of the mechanisms involved and role of SCD1. This book includes chapters by leading researchers on SCD Genes in the brain, heart, muscle, liver metabolism, Colitis, and more.
Implementations Of The Coordinated Operations Agreement Coa
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Author : United States. Congress. House. Committee on Interior and Insular Affairs. Subcommittee on Water and Power Resources
language : en
Publisher:
Release Date : 1987
Implementations Of The Coordinated Operations Agreement Coa written by United States. Congress. House. Committee on Interior and Insular Affairs. Subcommittee on Water and Power Resources and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Water quality management categories.
Acyl Coa Dehydrogenases Advances In Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Acyl Coa Dehydrogenases Advances In Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Science categories.
Acyl-CoA Dehydrogenases: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Acyl-CoA Dehydrogenases in a compact format. The editors have built Acyl-CoA Dehydrogenases: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Acyl-CoA Dehydrogenases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Acyl-CoA Dehydrogenases: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Acyl Coa Dehydrogenases Advances In Research And Application 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26
Acyl Coa Dehydrogenases Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Science categories.
Acyl-CoA Dehydrogenases—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Acyl-CoA Dehydrogenases in a compact format. The editors have built Acyl-CoA Dehydrogenases—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Acyl-CoA Dehydrogenases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Acyl-CoA Dehydrogenases—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Biochemistry
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Author : Pamela C. Champe
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2005
Biochemistry written by Pamela C. Champe and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
Lippincott’s Illustrated Reviews: Biochemistry has been the best-selling medical-level biochemistry review book on the market for the past ten years. The book is beautifully designed and executed, and renders the study of biochemistry enormously appealing to medical students and various allied health students. It has over 125 USMLE-style questions with answers and explanations, as well as over 500 carefully-crafted illustrations. The Third Edition includes end-of-chapter summaries, illustrated case studies, and summaries of key diseases.
Between Life And Death From Despair To Hope
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Author : Kashyap Patel
language : en
Publisher: Penguin Random House India Private Limited
Release Date : 2020-08-17
Between Life And Death From Despair To Hope written by Kashyap Patel and has been published by Penguin Random House India Private Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-17 with Literary Collections categories.
Dr Kashyap Patel is a renowned oncologist in the US who works with terminally ill cancer patients. Through him, we meet Harry, who, after a life full of adventure, is diagnosed with terminal lung cancer. As he stares death in the face, Harry leans on Dr Patel, an expert in understanding the process of death and dying. His questions and fears are addressed through the stories of many other patients that Dr Patel has treated-from the young and vivacious to those who had already lived full lives, from patients who could barely afford their rent to those who had been wildly successful. What ties these stories together is the single thread of the lessons Harry learns along the way, lessons that ultimately enable him to plan his own exit from the world gracefully-dying without fear.
Cloning And Characterization Of A Bovine Mammary Gland Cdna Encoding Acetyl Coa Synthetase
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Author : Ahmed M. Raafat
language : en
Publisher:
Release Date : 1994
Cloning And Characterization Of A Bovine Mammary Gland Cdna Encoding Acetyl Coa Synthetase written by Ahmed M. Raafat and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Acetylcoenzyme A synthetase categories.
Coa General Report
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Author : Xing zheng yuan nong ye wei yuan hui
language : en
Publisher:
Release Date : 1993
Coa General Report written by Xing zheng yuan nong ye wei yuan hui and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Agriculture categories.