Combination Therapies 2
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Combination Therapies
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Author : E. Garaci
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Combination Therapies written by E. Garaci and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Over the past decade many of the key lymphokines, hormones and growth factors that help regulate the immune system have been defined. These molecules, termed biological response modifiers (BRMs) , have been sequenced, synthesized and produced in large enough quantities to test in animals and humans resulting in the development of new approaches to the treatment of human disease, in particular, cancers and infectious diseases. Advances in this area have also led to rethinking therapies against a range of autoimmune disorders and other diseases associated with immune and endocrine imbalances. BRMs currently are being applied clinically as both primary and adjunctive therapy to enhance the effectiveness of traditional treatments by maximizing their activities and to protect critical tissues against intolerable chemotherapeutic and radiation damage. Present constraints against the use of BRMs revolve around the nature of these substances in vivo, where many of their actions and the majority of their interactions and synergies remain to be elucidated. For example, as these molecules are thought to exert their effects locally, the systemic administration of lymphokines, cytokines and growth factors at doses adequate to produce a wanted anti-tumor effect in many instances is intolerably toxic. Efforts to overcome this formidable problem have led scientists to begin to explore the transfer of genes known to encode for these molecules into cells which otherwise inadequately elicit or produce anti-tumor or anti-infective responses.
Combination Therapies 2
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Author : E. Garaci
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Combination Therapies 2 written by E. Garaci and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The 2nd International Symposium on Combination Therapies brought together several hundred of the leading researchers, scientists and clinicians in this area to discuss new and emerging uses for biological response modifiers (BRM's) in the treatment of cancer and infectious diseases. The meeting was held during May 1-3, 1992 in Acireale, Sicily (Italy). It was hosted by Professor G. Nicoletti CU. of Catania) and organized by the Institute for Advanced Studies in Immunology and Aging (Washington, D. C. ) in collaboration with the University of Rome "Tor Vergata," the University of Catania and The George Washington University Medical Center. The synergy exhibited between BRM's and conventional therapies including bone marrow and other lymphoid cell transplants is a rapidly expanding area with significant promise for the treatment of human diseases. Advances in this area of biomedicine are leading to the rapid development of new therapeutic approaches that are being applied clinically as both primary and adjuvant therapy to enhance the effectiveness of conventional treatments. The 2nd International Symposium on Combination Therapy provided a setting for the exchange of new scientific information regarding the emerging uses for BRM's alone or in combination with conventional therapies. The 1st International Symposium on Combination Therapies was held in 1991 in Washington, D. C.
Combination Therapies 2
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Author : E. Garaci
language : en
Publisher:
Release Date : 1993-10-01
Combination Therapies 2 written by E. Garaci and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-10-01 with categories.
Combination Therapy Against Multidrug Resistance
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Author : Mohmmad Younus Wani
language : en
Publisher: Academic Press
Release Date : 2020-04-30
Combination Therapy Against Multidrug Resistance written by Mohmmad Younus Wani and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-30 with Business & Economics categories.
Combination Therapy against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. Multidrug resistance (MDR) occurs when microorganisms such as bacteria, fungi, viruses, and parasites are excessively exposed to antimicrobial drugs such as antibiotics, antifungals, or antivirals, and in response the microorganism undergoes mutations or develops different resistance mechanisms to combat the drug for its survival. MDR is becoming an increasingly serious problem in both developed and developing nations. Bacterial resistance to antibiotics has developed faster than the production of new antibiotics, making bacterial infections increasingly difficult to treat, and the same is true for a variety of other diseases. Combination therapy proves to be a promising strategy as it offers potential benefits such as a broad spectrum of efficacy, greater potency than the drugs used in monotherapy, improved safety and tolerability, and reduction in the number of resistant organisms. This book considers how combination therapy can be applied in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Combination Therapy Against Multidrug Resistance gathers the most relevant information on the prospects of combination therapy as a strategy to combat multridrug resistance and helping to motivate the industrial sector and government agencies to invest more in research and development of this strategy as a weapon to tackle the multidrug resistance problem. It will be useful to academics and researchers involved in the development of new antimicrobial or antiinfective agents and treatment strtategies to combat multidrug resistance. Clinicians and medical nurses working in the field of infection prevention and control (IPC) will also find the book relevant Explores strategic methods with investigation of both short- and long-term goals to combat multidrug resistance Presents a broad scope to understand fully the ways to apply combined therapy to multidrug resistance Provides an overview of combination therapy, but also includes specific cases such as cancer, tuberculosis, HIV and malaria
Combination Cancer Therapy
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Author : Gary K. Schwartz
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-27
Combination Cancer Therapy written by Gary K. Schwartz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-27 with Medical categories.
Expert physician-scientists and clinicians review those combinations of novel target agents classic chemotherapies that hold the most promise for the future of medical oncology, and detail their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted therapies against cell surface receptors (EGF-R and HER2), the cell cycle (the CDKs), signal transduction events (PKC and NF-kB), apoptosis (bcl-2), as well as focused therapies in ovarian cancer, hematologic diseases, and breast cancer. The authors emphasize novel translational approaches that are rapidly moving from the laboratory bench top to the patient's bedside for the future treatments in cancer therapy.
Oral Combination Therapy With Thiazolidinediones And Sulfonylureas In Type 2 Diabetes
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Author :
language : en
Publisher:
Release Date : 2007
Oral Combination Therapy With Thiazolidinediones And Sulfonylureas In Type 2 Diabetes written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Combination Therapies New And Emerging Uses For Cyclooxygenase Inhibitors And Biological Response Modifiers On Immunity
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Author :
language : en
Publisher:
Release Date : 1989
Combination Therapies New And Emerging Uses For Cyclooxygenase Inhibitors And Biological Response Modifiers On Immunity written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with categories.
Combination Therapies And Their Effectiveness In Breast Cancer Treatment
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Author : Manzoor Ahmad Mir
language : en
Publisher:
Release Date : 2021-11
Combination Therapies And Their Effectiveness In Breast Cancer Treatment written by Manzoor Ahmad Mir and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11 with categories.
This book highlights up-to-date and novel information with clinical aspects regarding breast cancer. It covers aspects ranging from epidemiology, biology, and molecular classification to currently available and potentially new therapeutic options for breast cancer. It highlights insights into breast cancer at the molecular level with a holistic approach to use combinational strategies involving various therapies for targeting different pathways involved in this particular malignancy. This book contains a range of latest resources, including schematic illustrations, recent reviews, and information for patients with breast cancer. Various novel biomarkers that are under clinical investigation will also be discussed in this book. Furthermore, the relapse and recurrence after treatment with various therapies presents a great problem, as it develops resistance to which combinational strategy may prove to be a promising approach, and in this book, we have discussed all the aspects of combination therapy in breast cancer. People including students, research scholars, educators, pharmaceutical professionals, clinicians, researchers, practitioners and patients as well as their family members will find this book very much useful.
Novel Combination Therapies For The Treatment Of Solid Cancers
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Author : Khalid A. El Sayed
language : en
Publisher: Frontiers Media SA
Release Date : 2021-12-22
Novel Combination Therapies For The Treatment Of Solid Cancers written by Khalid A. El Sayed and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-22 with Science categories.
Combination Therapy For Hypothyroidism
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Author : Jacqueline Jonklaas
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-06
Combination Therapy For Hypothyroidism written by Jacqueline Jonklaas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-06 with categories.