Community Series Reducing The Burden Of Age Related Disease In Relation To Osteoporosis Sarcopenia And Osteosarcopenia Volume Ii

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Community Series Reducing The Burden Of Age Related Disease In Relation To Osteoporosis Sarcopenia And Osteosarcopenia Volume Ii

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Author : Bagher Larijani
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-10

Community Series Reducing The Burden Of Age Related Disease In Relation To Osteoporosis Sarcopenia And Osteosarcopenia Volume Ii written by Bagher Larijani and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-10 with Medical categories.

This Research Topic is the second volume of the Community Series, Reducing the Burden of Age-related Disease in relation to Osteoporosis, Sarcopenia and Osteosarcopenia. Please find the first Edition here. Osteoporosis is a common disease worldwide, resulting in nearly 9 million bone fractures globally per year. The number of people living with osteoporosis is set to dramatically increase in the coming decades, because of aging populations and lifestyle changes. Developing countries suffer more from osteoporosis due to limited availability of resources. Osteoporotic fractures are one of the most prevalent causes of disability and 1/3 women and 1/5 men >50 years will experience an osteoporotic fracture. Worldwide, 40% of osteoporotic fractures occur in people of working age. In women over 45 years of age, osteoporosis accounts for more days of hospitalization than diabetes, heart attacks or breast cancer. Fractures are also directly responsible for a 30% increase in mortality in the first year after the incidence. While the underlying cause of fragility fracture is osteoporosis, and a previous fracture increases the risk of the following fracture by nearly twofold in men and women, only 9%–50% of patients with fragility fractures have formal bone health assessment and treatments. According to a systematic review, bone density scans were ordered only for 1 to 32% of adults who experience a fragility fracture. Furthermore, post-hip fracture mortality rates vary between 25-30% in western countries, and 2-3 folds higher in populations from the Middle East and Africa region. Sarcopenia is a syndrome defined by loss of skeletal muscle mass and strength that gradually progresses by age and it is severely correlated with poor quality of life, dependency, and mortality. Documents showed that loss of muscle mass is associated with a higher duration of hospitalization and costs. The direct health care cost attributed to sarcopenia in U.S.A was estimated at $18.5 billion for the year 2000 (~ 1.5% of the total healthcare expenditure). The progressive loss in bone mineral density, muscle mass and strength are significant features of the aging process and the economic burden seems to significantly increase by the worldwide population aging. Osteosarcopenia, defined by the presence of sarcopenia and bone loss, can lead to higher clinical outcomes such as falls and fractures, while the information regarding this progressively increased geriatric syndrome is scarce. Despite the preventable nature of osteoporosis, sarcopenia and osteosarcopenia, and related complications, loss of accurate information on the distribution of related risk factors leftovers a major concern for policymakers in some countries and expanding appropriate interventions should be prioritized. To do this, a precise depiction of the situation, determination of the related risk factors in detail, providing acceptable strategies for prevention and treatment are required. The number of people living with dependency is set to dramatically increase in the coming decades due to aging populations and lifestyle changes. Musculoskeletal disorders are amongst the most impactful ailments that result in the inability to live independently. The forthcoming growth in the number of people living with dependency will place significantly greater demands on our systems of care. Despite much research for slowing the decline and prevention of related complications, lack of accurate information on the risk factors pose a major roadblock for policymakers in some countries as implementation of appropriate interventions needs to be prioritized. For these reasons, precise diagnosis of these disabilities, their underlying risk factors and proven strategies for prevention and treatment need definition.

Reducing The Burden Of Age Related Disease In Relation To Osteoporosis Sarcopenia And Osteosarcopenia

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Author : Bagher Larijani
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-09

Reducing The Burden Of Age Related Disease In Relation To Osteoporosis Sarcopenia And Osteosarcopenia written by Bagher Larijani and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-09 with Medical categories.

Osteosarcopenia Bone Muscle And Fat Interactions

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Author : Gustavo Duque
language : en
Publisher: Springer Nature
Release Date : 2019-11-06

Osteosarcopenia Bone Muscle And Fat Interactions written by Gustavo Duque and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-06 with Science categories.

This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies. With our aging population, chronic diseases such as osteoporosis and sarcopenia are becoming highly prevalent. Fortunately, our understanding of the bone and muscle interactions has increased in recent years. This has allowed to the coining of the term osteosarcopenia to describe a syndrome in which these two diseases overlap. This overlap between osteoporosis and sarcopenia has major negative effects not only on our older adults but also on health systems worldwide. Readers will find a highly translational approach that starts with a summary of recent discoveries on stem cells biology, muscle and bone interactions – including the role of local bone and muscle fat – followed by comprehensive reviews on myokines (i.e. myostatin), osteokines (i.e. osteocalcin) and adipokines (i.e. interleukins) as major players and determinants of bone and muscle loss with aging. In addition, the role of sex steroids (i.e. estrogens, androgens), and calciotropic hormones (i.e. parathyroid hormone, vitamin D) in the pathogenesis of this syndrome is also reviewed. Moreover, using practical diagnostic and therapeutic tips, this book summarizes the clinical characteristics of osteosarcopenic patients thus facilitating the diagnosis and treatment of this syndrome in clinical practice. Finally, the book presents the case for the Falls and Fractures Clinic as the optimal model of care for this syndrome, aimed to avoid fragmentation and optimize osteosarcopenia care, and simultaneously prevent falls and fractures in older persons. This book offers relevant information on the mechanisms of osteosarcopenia, and a practical guide on how to identify and treat this geriatric syndrome and its adverse outcomes, which are dramatically affecting our aging population. The work is written by leaders in the field and is especially suited not only to any researcher in the musculoskeletal arena but also to medical specialists and allied health professionals involved in the care of older persons.

Osteosarcopenia

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Author : Gustavo Duque
language : en
Publisher: Elsevier
Release Date : 2022-03-04

Osteosarcopenia written by Gustavo Duque and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-04 with Medical categories.

Falls, fractures, frailty, osteoporosis and sarcopenia are highly prevalent in older persons. While the concept of osteosarcopenia is new, it is a rapidly evolving and cross-disciplinary problem. Prevention and treatment are challenging and a combined therapeutic approach is needed. Osteosarcopenia provides evidence-based information on how to prevent and treat these conditions at multiple settings, including multiple illustrations, care pathways and tips to easily understand the pathophysiology, diagnostic methods and therapeutic approach to these conditions. This work evaluates the potential for a link between osteoporosis, sarcopenia and obesity. Presents diagnostic and therapeutic tips that facilitate the design and implementation of new care pathways, impacting the wellbeing of our older population Provides cross-disciplinary understanding by experts from the bone/osteoporosis field and the muscle/sarcopenia field Covers muscle and bone biology, mesenchymal stem cells, age-related changes and cross-talk between muscle, fat and bone, falls and fracture risk, glucose metabolism, diagnosis, imaging, and genetics of osteosarcopenia

Exercise To Prevent And Manage Chronic Disease Across The Lifespan

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Author : Jack Feehan
language : en
Publisher: Academic Press
Release Date : 2022-04-30

Exercise To Prevent And Manage Chronic Disease Across The Lifespan written by Jack Feehan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-30 with Science categories.

Exercise to Prevent and Manage Chronic Disease Across the Lifespan provides evidence-based insights into the clinical utility of exercise in the management of disease across a broad range of specialties and diseases. The book offers research informed strategies for the integration of exercise into standard practice in fields such as neurology, endocrinology, psychiatry and oncology, as well as decision-making pathways and clinical scenarios to advance patient care. The book is divided by specialty and includes clinical scenarios to allow for the integration of information within practice. The book's synthesized research evidence allows practitioners to safely and effectively begin to capitalize on the benefits of exercise in their patients. Provides broad insights into the evidence-based underpinnings of the use of exercise in a range of common diseases Coverage includes the immune system, musculoskeletal disease, oncology, endocrinology, cardiology, respiratory diseases, and more Includes a glossary, bibliography and summary figures for quick reference of information

Nutritional Aspects Of Kidney Disease

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Author : Alice Sabatino
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-10

Nutritional Aspects Of Kidney Disease written by Alice Sabatino and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-10 with Medical categories.

Orthogeriatrics

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Author : Paolo Falaschi
language : en
Publisher: Springer Nature
Release Date : 2021

Orthogeriatrics written by Paolo Falaschi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Anesthesiology categories.

This new open access edition supported by the Fragility Fracture Network aims at giving the widest possible dissemination on fragility fracture (especially hip fracture) management and notably in countries where this expertise is sorely needed. It has been extensively revised and updated by the experts of this network to provide a unique and reliable content in one single volume. Throughout the book, attention is given to the difficult question of how to provide best practice in countries where the discipline of geriatric medicine is not well established and resources for secondary prevention are scarce. The revised and updated chapters on the epidemiology of hip fractures, osteoporosis, sarcopenia, surgery, anaesthesia, medical management of frailty, peri-operative complications, rehabilitation and nursing are supplemented by six new chapters. These include an overview of the multidisciplinary approach to fragility fractures and new contributions on pre-hospital care, treatment in the emergency room, falls prevention, nutrition and systems for audit. The reader will have an exhaustive overview and will gain essential, practical knowledge on how best to manage fractures in elderly patients and how to develop clinical systems that do so reliably.

Postmenopausal Diseases And Disorders

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Author : Faustino R. Pérez-López
language : en
Publisher: Springer
Release Date : 2019-07-10

Postmenopausal Diseases And Disorders written by Faustino R. Pérez-López and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-10 with Medical categories.

Supported by the latest scientific data, this book serves as a guide to the clinical assessment of women’s health during the second half of life (post-reproductive years), including approaches to the management of the most frequent age-related diseases and disorders and the most recent advances in treatment. In addition, it discusses preventive aspects of healthcare in post-reproductive women, identifying lifestyle measures to enhance healthy aging. By highlighting research gaps, it promotes the development of quick and easy-to-use assessment tools and predictive markers of age-related co-morbidities. As such, the book is a valuable resource for researchers and clinicians alike.

Nutritional Influences On Bone Health

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Author : Connie M. Weaver
language : en
Publisher: Springer
Release Date : 2018-10-24

Nutritional Influences On Bone Health written by Connie M. Weaver and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-24 with Medical categories.

This book comprehensively covers the topics and discussions covered at the 10th International Symposium on Nutritional Aspects of Osteoporosis. It is the only international meeting that exclusively covers the role of nutrition on musculoskeletal health and function. Current thinking on the role of nutrition on bone and muscle development and health, and as a means of preventing osteoporosis, falls and fractures is covered. The latest evidence on the potential roles that protein, potassium, B vitamins, vitamin D, omega-3 fatty acids, and flavonoids in the context of bone and muscle health are also discussed. Nutritional Influences on Bone Health reviews the role of nutrition in bone health and its potential role in preventing osteoporosis and sarcopenia in ageing populations, providing a valuable and practically applicable resource for practising and trainee health and medical professionals.

Male Osteoporosis

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Author : Alberto Ferlin
language : en
Publisher: Springer Nature
Release Date : 2020-09-07

Male Osteoporosis written by Alberto Ferlin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-07 with Medical categories.

This book represents a comprehensive, clinically oriented text covering all aspects of male osteoporosis, from the basic concepts of bone physiology and regulation of bone remodeling in men, the causes and pathophysiological mechanisms responsible for the most frequent causes of osteoporosis, to diagnostic and screening protocols, as well as prevention and treatment approaches. It offers a broad overview of male osteoporosis by specialists involved in research and clinical practice and discusses the practical issues encountered. Filling a gap in the literature, this volume is a valuable resource for general practitioners, clinical endocrinologists, geriatricians and experts in osteoporosis.