Coronary Circulation
DOWNLOAD
Download Coronary Circulation PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Coronary Circulation book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Coronary Circulation
DOWNLOAD
Author : J.A. Spaan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Coronary Circulation written by J.A. Spaan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Few diagnostic methods in Cardiology have heralded such revolutionary developments as the introduction of coronary arteriography. When, in the early 1960's, Dr. F. Mason Sones demonstrated that visualization of the coronary anatomy in living humans was not only feasible but sufficiently safe and reliable to be used as a clinical tool in the evaluation of patients with known or suspected ischemic heart disease, the thus far somewhat neglected area of coronary circulation became the focus of interest. Naturally, for a considerable period of time a great deal of emphasis was placed upon coronary anatomy. Simple relations between narrowing lesions, impediment to flow, and prognosis were assumed to exist. Spectacular results of surgical coronary revascularization seemed to confirm this concept. Gradually it has become evident that the pathophysiology of coronary artery disease is considerably more complex. Diagnostic methods were introduced to assess and quantify exercise-induced myocardial ischemia. At first, these tests were used mainly to achieve a more discriminative selection of candidates for coronary arteriography and the coronary arteriogram remained the gold standard. Currently, these techniques have evolved to the point where they provide valuable functional and metabolic information. They have become powerful independent tools in clinical investigations and evaluation of individual patients.
Coronary Circulation
DOWNLOAD
Author : Johnathan D. Tune
language : en
Publisher: Biota Publishing
Release Date : 2014-07-01
Coronary Circulation written by Johnathan D. Tune and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-01 with Medical categories.
The coronary circulation is unique in that it is responsible for maintaining adequate oxygen and substrate delivery to the organ that generates the pressure needed to drive blood throughout the entire circulatory system. In the simplest terms, coronary blood flow is directly proportional to the arterial pressure gradient across the coronary vasculature and inversely proportional to coronary vascular resistance. However, myocardial perfusion is collectively regulated by a complex variety of mechanisms which include: (1) extravascular compressive forces; (2) diastolic time fraction; (3) coronary perfusion pressure; (4) myocardial metabolism (local metabolic factors); (5) endothelial-derived substances; (6) neuro-humoral influences; and (7) arterial oxygen tension and content. This book considers each of these determinants with particular emphasis on the functional interaction between the physical and biological determinants of myocardial perfusion. Pathophysiologic aspects of coronary atherosclerosis and cardiovascular disease states are also considered. Table of Contents: Abbreviations / Acknowledgments / Introduction / Basic Coronary Anatomy / Myocardial-Coronary Interaction / Arterial Pressure and Autoregulation / Local Metabolic Control / Endothelial-Dependent Control / Neural Activation and Circulating Hormones / Coronary Stenosis, Myocardial Ischemia, and Effects of Disease / Summary / Reference List / Author Biography
Coronary Circulation
DOWNLOAD
Author : Ghassan S. Kassab
language : en
Publisher: Springer
Release Date : 2019-05-15
Coronary Circulation written by Ghassan S. Kassab and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-15 with Science categories.
This comprehensive text examines both global and local coronary blood flow based on morphometry and mechanical properties of the coronary vasculature. Using a biomechanical approach, this book addresses coronary circulation in a quantitative manner based on models rooted in experimental data that account for the various physical determinants of coronary blood flow including myocardial-vessel interactions and various mechanisms of autoregulation. This is the first text dedicated to a distributive analysis (as opposed to lumped) and provides digital files for detailed anatomical data (e.g., diameters, lengths, node-to-node connections) of the coronary vessels. This book also provides appendices with specific mathematical formulations for the biomechanical analyses and models in the text. Written by Dr. Ghassan S. Kassab, a leader in the field of coronary biomechanics, Coronary Circulation: Anatomy, Mechanical Properties, and Biomechanics is a synthesis of seminal topics in the field and is intended for clinicians, bioengineers, and researchers as a compendium on the topic. The detailed anatomical and mechanical data provided are intended to be used as a platform to address new questions in this exciting and clinically very important research area.
Coronary Circulation
DOWNLOAD
Author : Fumihiko Kajiya
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Coronary Circulation written by Fumihiko Kajiya and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Coronary heart disease is one of the major health problems in indus trialized nations because of its high incidence and severity. Recent innovations in medical and surgical treatment of coronary heart dis ease have increased the importance of accurate diagnostic methods for determining the severity of coronary disease, identifying potential treatment alternatives, and evaluating the results of treatment. Great advances have also been made in basic research on coronary circula tion and its interaction with myocardial contraction and relaxation and neural and humoral control. With respect to these developments, the papers included in the present monograph deal with important topics concerned with the basic mechanism of coronary circulation as well as ones of clinical relevance. It is directed toward physicians (cardiologists, cardiac surgeons, cardiac radiologists, anestheologists, and others) and basic scientists (e.g., physiologists, bioengineers). We would like to em phasize the importance of a multidisciplinary approach in which basic scientists and clinicians work closely together. This volume consists of nine chapters. Chapter 1 contains macro scopic and microscopic descriptions of coronary vascular anatomy, which is closely related to the functions of coronary circulation. In Chap. 2 two methods in current use to evaluate phasic coronary blood velocity waveforms are presented, i.e., the laser Doppler and ultrasound Doppler methods. Chapter 3 describes the mechanical properties of coronary circulation, a knowledge of which is indispens able for an understanding of coronary arterial and venous blood flow velocity waveforms in relation to cardiac contraction and relaxation.
Coronary Circulation In Physiological And Pathophysiological States
DOWNLOAD
Author : Motoomi Nakamura
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Coronary Circulation In Physiological And Pathophysiological States written by Motoomi Nakamura and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
MOTOOMI NAKAMURA As we approach the 21st century, ischemic heart disease is the major cause of death in most of the developed nations of the world. Since the 1970s, much effort and expense have led to designs of coronary thrombolytic therapy, percutaneous coronary angioplasty (PTCA), coronary artery bypass grafting, heart transplantation, automatic defibrillators, as well as to the formation of beta blockers and com pounds which block the calcium channel. Socio-educational programs directed at exercise, diet, instruction in the risk factors of smoking, hyperlipidemia and hypertension have contributed to the decrease in the rate of morbidity and mortality of patients with ischemic heart disease. However, the first clinical event of ischemic heart disease, the so-called "heart attack" and sudden cardiac death continues to present problems, as the mechanisms involved in these events are poorly understood. It has long been thought that ischemic heart disease is the sequence of an organic fixed atherosclerotic obstruction of the epicardial coronary arteries and the role of coronary vasomotion has been given much less attention. Recent clinical and laboratory animal studies revealed that increased tonus and spasm of the large epicardial coronary arteries are the cause of various stages of ischemic heart disease. The role of coronary vasospasm in the development of un stable angina, sudden cardiac death and acute myocardial infarction remains open to debate. Pharmacophysiological studies showed that the epicardial large coronary artery contributes only 5% to regulation of normal coronary flow.
The Coronary Circulation In Health And Disease
DOWNLOAD
Author : Melvin L. Marcus
language : en
Publisher: McGraw-Hill Companies
Release Date : 1983
The Coronary Circulation In Health And Disease written by Melvin L. Marcus and has been published by McGraw-Hill Companies this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Medical categories.
Pharmacology Of The Coronary Circulation
DOWNLOAD
Author : Natalii︠a︡ V Kaverina
language : en
Publisher:
Release Date : 1965
Pharmacology Of The Coronary Circulation written by Natalii︠a︡ V Kaverina and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1965 with Cardiovascular agents categories.
"Diseases associated with impairment of the coronary circulation are very common. Hence, the treatment of such diseases is a matter of considerable importance. It is now considered one of the main problems of clinical medicine. The basis for solving the problem is to enlarge our knowledge of the mechanisms of action of the drugs used to treat coronary insufficiency and to find new effective agents. Owing to the complexity of physiological regulation of the coronary circulation, there are many difficulties of a procedural order in studying it experimentally. This was one of the reasons why ideas on the action of many pharmacological agents were derived until recently from the results of experiments involving the isolated heart. When applied to the intact organism, these ideas proved to be inexact and, at times, wrong. Some ideas on the effects of certain drugs were based on experiments involving the intact organism, but the data proved to be inexact due to the inadequacy of the method selected by the authors to determine the mechanism of action of a given substance. Another reason for misconceptions of the effects of some drugs stemmed from insufficient knowledge and contradictory opinions expressed by various investigators on many aspects of the coronary circulation. Now, however, advances in experimental techniques have produced new facts bearing on the physiological regulation of the cardiac blood supply. This has given rise to the need to reexamine some matters concerned with the influence of pharmacological agents on the coronary circulation, relying on modern ideas concerning its physiological regulation and using adequate experimental techniques. Most drugs have complex mechanisms of action owing to the intimate relationship between the processes regulating the cardiac blood supply. Elucidation of these mechanisms requires the use of various techniques, each of which must be suited to the particular aspect under study. This approach will result in a reappraisal of the action of several pharmacological agents on the coronary circulation. Moreover, we believe that the data in this book will be helpful in making more efficient use of these agents in the treatment of various forms of coronary insufficiency."--Introduction
Coronary Circulation In The Normal And The Pathologic Heart
DOWNLOAD
Author : Giorgio Baroldi
language : en
Publisher:
Release Date : 1967
Coronary Circulation In The Normal And The Pathologic Heart written by Giorgio Baroldi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1967 with Blood categories.
Coronary Circulation And Myocardial Ischemia
DOWNLOAD
Author : Michael R. Pinsky
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Coronary Circulation And Myocardial Ischemia written by Michael R. Pinsky and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The coronary circulation is central to sustaining myocardial viability. Unlike the cir culations of most other organs, if the coronary circulation becomes insufficient to sustain myocardial contractile function, overall quality of life rapidly declines and life can abruptly end. In partnership with the cerebral circulation, the coronary circula tion plays a central role in sustaining life. However, unlike the cerebral circulation, whose function is self-sufficient to define life, the coronary circulation determines global blood flow and thus the initial state for the remainder of the body. This unique condition, together with the reality that coronary artery disease primarily affects peo ple in their productive years of life, has allowed physicians and scientists who study the heart to enjoy a privileged position in the field of medical research and clinical practice. Thus, it comes as little surprise that many new and exciting research developments involving the coronary circulation have recently come to the forefront of medical thinking. This reality, coupled with the large number of clinical trials of agents specif ically designed to sustain or improve coronary flow in many disease states, makes the timing of this monograph relevant. The book features papers presented at a recent international symposium, the fourth in a series of meetings on Applied Physiology of the Peripheral Circulation. The papers selected by the editors review the most impor tant advances in the fields of cardiology and the coronary circulation.
The Physics Of Coronary Blood Flow
DOWNLOAD
Author : M. Zamir
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-06-18
The Physics Of Coronary Blood Flow written by M. Zamir and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-18 with Science categories.
The fields of biological and medical physics and biomedical engineering are broad, multidisciplinary and dyanmic. They lie at the crossroads of frontier - search in physics, biology, chemistry, and medicine. The Biological & Me- cal Physics/Biomedical Engineering Series is intended to be comprehensive, covering a broad range of topics important to the study of the physical, che- cal and biological sciences. Its goal is to provide scientists and engineers with textbooks, monographs, and reference works to address the growing need for information. Books in the series emphasize established and emergent areas of science - cluding molecular, membrane, and mathematical biophysics; photosynthetic - ergy harvesting and conversion; information processing; physical principles of genetics; sensory communications; automata networks, neural networks, and cellular automata. Equally important will be coverage of applied aspects of b- logical and medical physics and biomedical engineering such as molecular el- tronic components and devices, biosensors, medicine, imaging, physical prin- ples of renewable energy production, advanced prostheses, and environmental control and engineering. Elias Greenbaum Oak Ridge, TN M. Zamir Department of Applied Mathematics University of Western Ontario London, Ontario, N6A 5B7 CANADA [email protected] Library of Congress Cataloging-in-Publication Data Zamir, M. (Mair) The physics of coronary blood flow / M. Zamir. p. cm. — (Biological and medical physics, biomedical engineering) Includes bibliographical references and index. 1. Coronary circulation. 2. Hemodynamics. 3. Blood flow. I. Title. II. Series. QP108.Z36 2005 612.1?7—dc22 2005042502 ISBN-10: 0-387-25297-5 e-ISBN: 0-387-26019-6 Printed on acid-free paper.