Cyclic Gmp
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Cyclic Gmp Synthesis Metabolism And Function
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Author :
language : en
Publisher: Academic Press
Release Date : 1994-05-18
Cyclic Gmp Synthesis Metabolism And Function written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-05-18 with Medical categories.
This volume is dedicated to the topic of cyclic GMP. Chapters include discussions on the guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis, cyclic GMP-dependent protein kinases, and various hormones and ligands that regulate cyclic GMP formation and/or metabolism. Several chapters also deal with some of the effects of cyclic GMP on other second messengers such as calcium ion transport and smooth muscle relaxation. Some clinical studies with cyclic GMP and atrial natriuretic peptide are also discussed. The last chapter raises many important questions in the field that remain to be addressed. Isoforms of guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis Cyclic GMP-dependent protein kinase Hormones and ligands that regulate GMP formation and/or metabolism Effects of cyclic GMP on other second messengers and some functions such as smooth muscle relaxation and ion transport Clinical studies with cyclic GMP and atrial natriuretic peptide Important questions and experiments for the future
Cyclic Gmp
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Author : Thomas M. Lincoln
language : en
Publisher: Landes Bioscience
Release Date : 1994
Cyclic Gmp written by Thomas M. Lincoln and has been published by Landes Bioscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Science categories.
Guanylate Cyclase And Cyclic Gmp
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Author : Thomas Krieg
language : en
Publisher: Humana
Release Date : 2016-08-23
Guanylate Cyclase And Cyclic Gmp written by Thomas Krieg and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Science categories.
Recently, many ground-breaking steps have been made towards better understanding NO/cGMP/PKG pathways, its components, substrates, and their localization within a given cell. These advances were only possible due to the development of sophisticated new techniques in the field. In Guanylate Cyclase and Cyclic GMP: Methods and Protocols expert researchers in the field seek to provide an overview of novel techniques to identify various elements of the NO/cGMP/PKG pathway and further characterize their function, signaling, localization, and importance on a cellular level and in whole animal models providing a higher patho-/physiological integration and relevance. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Guanylate Cyclase and Cyclic GMP: Methods and Protocols seeks to provide scientist current methods and a useful guide towards the possibility to apply these techniques to their own research.
Cgmp Generators Effectors And Therapeutic Implications
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Author : Harald H. H. W. Schmidt
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-17
Cgmp Generators Effectors And Therapeutic Implications written by Harald H. H. W. Schmidt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-17 with Science categories.
After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.
Reviews Of Physiology Biochemistry And Pharmacology
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Author : G. Schultz
language : en
Publisher: Springer
Release Date : 2014-08-23
Reviews Of Physiology Biochemistry And Pharmacology written by G. Schultz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-23 with Science categories.
This special volume provides up-to-date information on research dealing with the regulation of the biosynthesis and degradation of cyclic GMP and with the regulation of physiological systems by cyclic GMP. The publication of this volume could not have come at a more appropriate time, with significant work in this area having led to our current understanding of the role of nitric oxide in signal transduction, and the 1998 Nobel Prize in Medicine and Physiology for Furchgott, Murad and Ignarro. Moreover, the introduction in early 1998 of sildenafil (Viagra), a selective inhibitor of a cyclic GMP phosphodiesterase, for the treatment of erectile dysfunction in men represents the first successful therapeutic application of an agent designed to alter the activity of a molecular target in a cyclic GMP pathway.
Guanine Nucleotides In The Regulation Of Synthesis And Function Of Cyclic Gmp In The Cardiovascular System And Blood Cells
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Author : Pauli Vuorinen
language : en
Publisher:
Release Date : 1992
Guanine Nucleotides In The Regulation Of Synthesis And Function Of Cyclic Gmp In The Cardiovascular System And Blood Cells written by Pauli Vuorinen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Cyclic guanylic acid categories.
Effects Of Cyclic Gmp On The Behavior Of Paramecium Tetraurelia
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Author : Danzhu Lu
language : en
Publisher:
Release Date : 1989
Effects Of Cyclic Gmp On The Behavior Of Paramecium Tetraurelia written by Danzhu Lu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with categories.
The Second Messenger Cyclic Di Gmp
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Author : Alan J. Wolfe
language : en
Publisher: American Society for Microbiology Press
Release Date : 2010-01-05
The Second Messenger Cyclic Di Gmp written by Alan J. Wolfe and has been published by American Society for Microbiology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-05 with Science categories.
A comprehensive reference on the state of the science for both experienced researchers and for those who are interested in discovering its many promising applications. • Examines c-di-GMP signaling from a variety of angles, beginning with an introductory chapter that compares c-di-GMP to the better-known second messenger cAMP. • Recounts the discovery of c-di-GMP, explains the important role of bioinformatics in the development and continued evolution of the field, and describes the fundamental structure, function, regulation, and integration of c-di-GMP pathways. • Explores the role of c-di-GMP in such diverse processes as flagellar biogenesis and motility, extracellular polysaccharide biosynthesis, biofilm development, virulence, and innate host immunity.
On The Role Of Cyclic Gmp As A Modulator Of The Cell Metabolism Of Hypoxic And Ischaemic Rat Heart
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Author : Kai Laustiola
language : en
Publisher:
Release Date : 1984
On The Role Of Cyclic Gmp As A Modulator Of The Cell Metabolism Of Hypoxic And Ischaemic Rat Heart written by Kai Laustiola and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Cell metabolism categories.
Purification And Characterization Of Cyclic Gmp Dependent Protein Kinase From Paramecium
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Author : Leslie Allison Piper Miglietta
language : en
Publisher:
Release Date : 1987
Purification And Characterization Of Cyclic Gmp Dependent Protein Kinase From Paramecium written by Leslie Allison Piper Miglietta and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with categories.