Drug Resistance In Bacteria
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Drug Discovery Targeting Drug Resistant Bacteria
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Author : Prashant Kesharwani
language : en
Publisher: Academic Press
Release Date : 2020-05-15
Drug Discovery Targeting Drug Resistant Bacteria written by Prashant Kesharwani and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-15 with Medical categories.
Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war
Antibiotic Drug Resistance
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Author : José-Luis Capelo-Martínez
language : en
Publisher: John Wiley & Sons
Release Date : 2019-09-24
Antibiotic Drug Resistance written by José-Luis Capelo-Martínez and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-24 with Medical categories.
This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Antibiotic Resistant Bacteria A Challenge To Modern Medicine
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Author : Sadhana Sagar
language : en
Publisher: Springer Nature
Release Date : 2019-11-14
Antibiotic Resistant Bacteria A Challenge To Modern Medicine written by Sadhana Sagar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-14 with Medical categories.
This book summarizes the emerging trends in the field of antibiotic resistance of various gram-negative and gram-positive bacterial species. The ability of different species of bacteria to resist the antimicrobial agent has become a global problem. As such, the book provides a comprehensive overview of the advances in our understanding of the origin and mechanism of resistance, discusses the modern concept of the biochemical and genetic basis of antibacterial resistance and highlights the clinical and economic implications of the increased prevalence of antimicrobial resistant pathogens and their ecotoxic effects. It also reviews various strategies to curtail the emergence and examines a number of innovative therapeutic approaches, such as CRISPR, phage therapy, nanoparticles and natural antimicrobials, to combat the spread of resistance.
Impacts Of Antibiotic Resistant Bacteria
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Author :
language : en
Publisher: DIANE Publishing
Release Date : 1995
Impacts Of Antibiotic Resistant Bacteria written by and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Antibacterial agents categories.
Antibiotic Resistance
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Author : Derek J. Chadwick
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Antibiotic Resistance written by Derek J. Chadwick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Medical categories.
Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use of antibiotics, not only in people, but also in animal husbandry and agriculture, has delivered a selection unprecedented in the history of evolution. Consequently, society is facing one of its gravest public health problems-the emergence of infectious bacteria with resistance to many, and in some cases all, available antibiotics. This book brings together a multidisciplinary group of experts to discuss this problem. It begins by examining the origins of resistance and goes on to look at how the use of antibiotics in human medicine and farming/agriculture has selected for resistant bacteria. Separate chapters describe the evolution of resistance determinants and how these are spread both within and between bacterial species. Finally, the book contains discussions on strategies for countering the threat of antibiotic resistance. A major re-thinking of our approach to the treatment of infectious diseases is proposed-that antibiotic resistance should be seen as a problem created by the disruption of normal microbial ecology. To restore efficacy to earlier antibiotics, and to maintain the success of new antibiotics that are introduced, we need to use these drugs in a way that ensures an ecological balance that favours the predominance of susceptible bacteria.
Bacterial Resistance To Antibiotics
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Author : Boyan B. Bonev
language : en
Publisher: John Wiley & Sons
Release Date : 2019-03-14
Bacterial Resistance To Antibiotics written by Boyan B. Bonev and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-14 with Science categories.
AN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant "Superbugs." The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths. Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic era—when diseases caused by parasites or infections were virtually untreatable and frequently resulted in death—new and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics. Bacterial Resistance to Antibiotics – From Molecules to Man examines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more. Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradability Highlights critical aspects that may relieve the problematic medical situation of antibiotic resistance Includes an overview of the genetic and molecular mechanisms of antibiotic resistance Addresses contemporary issues of global public health and longevity Includes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics – From Molecules to Man is a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.
Antibiotic Resistant Bacteria
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Author : Marina Pana
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-04-04
Antibiotic Resistant Bacteria written by Marina Pana and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-04 with Medical categories.
Antibiotic-resistant bacterial strains remain a major global threat, despite the prevention, diagnosis and antibiotherapy, which have improved considerably. In this thematic issue, the scientists present their results of accomplished studies, in order to provide an updated overview of scientific information and also, to exchange views on new strategies for interventions in antibiotic-resistant bacterial strains cases and outbreaks. As a consequence, the recently developed techniques in this field will contribute to a considerable progress in medical research.
Superbugs
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Author : William Hall
language : en
Publisher: Harvard University Press
Release Date : 2018-04-09
Superbugs written by William Hall and has been published by Harvard University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-09 with Medical categories.
Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading. Unnecessary use of antibiotics in both humans and animals accelerates the evolution of drug-resistant bacteria, with potentially catastrophic personal and global consequences. Our best defenses against infectious disease could cease to work, surgical procedures would become deadly, and we might return to a world where even small cuts are life-threatening. The problem of drug resistance already kills over one million people across the world every year and has huge economic costs. Without action, this problem will become significantly worse. Following from their work on the Review on Antimicrobial Resistance, William Hall, Anthony McDonnell, and Jim O’Neill outline the major systematic failures that have led to this growing crisis. They also provide a set of solutions to tackle these global issues that governments, industry, and public health specialists can adopt. In addition to personal behavioral modifications, such as better handwashing regimens, Superbugs argues for mounting an offense against this threat through agricultural policy changes, an industrial research stimulus, and other broad-scale economic and social incentives.
Drug Resistance In Bacteria Fungi Malaria And Cancer
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Author : Gunjan Arora
language : en
Publisher: Springer
Release Date : 2017-03-21
Drug Resistance In Bacteria Fungi Malaria And Cancer written by Gunjan Arora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-21 with Medical categories.
This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.Human survival on earth is constantly threatened by disease and syndrome. From the early days, the aim of research in medicine was to find therapeutic agents that can improve the quality of human life. Although humans are dependent on natural compounds from early days their dependence of drugs increased excessively in last century. The advances in chemistry and biology have helped researchers to identify the drugs that have improved treatment of many diseases. The primary factor for treatment of these diseases is dependent on the efficacy of drugs available. The development of resistance to these drugs is one of the major hindrances. Although there are number of books available on this topic, “drug resistance” biology across kingdoms has never been discussed in a coherent way.
The Microbes Fight Back
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Author : Laura Bowater
language : en
Publisher: Royal Society of Chemistry
Release Date : 2017-10-25
The Microbes Fight Back written by Laura Bowater and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-25 with Medical categories.
Antibiotics are familiar drugs to us all, so familiar that we may take them for granted. They allow us to survive life-threatening infections, and allow us to protect the animals we farm for food. Many antibiotics have now become ineffective against common diseases, and there are few alternative treatments to replace them. In this topical popular science book, Laura Bowater, Professor of Microbiology Education and Engagement at Norwich Medical School, considers the past, present and uncertain future of antibiotics. This book begins by looking back at how infectious diseases, such as smallpox and the plague, were able to wreak havoc on populations before the discovery of the first antibiotics. These then revolutionised the medical world. In an engaging and accessible style, Professor Bowater takes the reader through how antibiotics are made, how bacteria are able to mutate and develop resistance and she explains why there is now a lack of new antibiotic drugs coming to market. What will a future of continued antibiotic resistance look like? How can human activities prevent the rise of ‘superbugs'? Professor Bowater highlights the need for universal cooperation in order to tackle this global health challenge, which, if not addressed, could transport us back to the medical dark ages.