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Dttp

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Author :
language : en
Publisher:
Release Date : 1999

Dttp written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Documents librarians categories.

Documents To The People

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Author :
language : en
Publisher:
Release Date : 1992

Documents To The People written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Documents librarians categories.

Metabolic Pathways

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Author : David Greenberg
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Metabolic Pathways written by David Greenberg and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.

Metabolic Pathways, Third Edition: Volume IV: Nucleic Acids, Protein Synthesis, and Coenzymes focuses on the metabolic pathways of the major biological constituents of living organisms, namely, nucleic acids, proteins, and coenzymes. The biosynthesis and metabolism of purines and pyrimidines, nucleotides, riboflavin and related compounds, and vitamin B6 are discussed. The biogenesis and metabolism of thiamine and folic acid are also considered. This volume is comprised of seven chapters and begins with an analysis of metabolic control and enzymology of purines and pyrimidines such as inosinic acid and nucleotides. The next chapter is devoted to the biosynthesis and metabolism of nucleotides and nucleic acids, making reference to deoxyribonucleotides as well as RNA and DNA. Some of the reactions involving nucleotides are classified and briefly discussed. The reader is then introduced to protein synthesis, paying particular attention to the chemical features of the synthesis of the peptide bond and the characteristics of the genetic code implicated in this process. The remaining chapters focus on riboflavin and related compounds, thiamine, folic acid, and vitamin B6. This book will be a useful resource for biochemists and biologists.

Dna Replication

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Author : Arthur Kornberg
language : en
Publisher: University Science Books
Release Date : 2005-06-24

Dna Replication written by Arthur Kornberg and has been published by University Science Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-06-24 with Science categories.

DNA Replication, second edition, a classic of modernscience, is now back in print in a paperback edition. Kornberg and Baker'sinsightful coverage of DNA replication and related cellular processes have madethis the standard reference in the field.

Viral Polymerases And Related Proteins

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Author : Lawrence C. Kuo
language : en
Publisher: Elsevier
Release Date : 1996

Viral Polymerases And Related Proteins written by Lawrence C. Kuo and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with DNA Polymerases categories.

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 270 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features* Expression, purification, and characterization* Activity assays* Kinetic and screening* Design and analysis of substrates and inhibitors* Molecular and structural characterizations.

Dna Damage Dna Repair And Disease

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Author : Miral Dizdaroglu
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-11-11

Dna Damage Dna Repair And Disease written by Miral Dizdaroglu and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-11 with Science categories.

The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.

Antineoplastic And Immunosuppressive Agents

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Author : Alan C. Sartorelli
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-27

Antineoplastic And Immunosuppressive Agents written by Alan C. Sartorelli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-27 with Medical categories.

Over the past two decades a number of attempts have been made, with varying degrees of success, to collect in a single treatise available information on the basic and applied pharmacology and biochemical mechanism of action of antineoplastic and immunosuppressive agents. The logarithmic growth of knowledge in this field has made it progressively more difficult to do justice to all aspects of this topic, and it is possible that the present handbook, more than four years in preparation, may be the last attempt to survey in a single volume the entire field of drugs employed in cancer chemotherapy and immunosuppression. Even in the present instance, it has proved necessary for practical reasons to publish the material in two parts, although the plan of the work constitutes, at least in the editors' view, a single integrated treatment of this research area. A number of factors have contributed to the continuous expansion of research in the areas of cancer chemotherapy and immunosuppression. Active compounds have been emerging at ever-increasing rates from experimental tumor screening systems maintained by a variety of private and governmental laboratories through out the world. At the molecular level, knowledge of the modes of action of established agents has continued to expand, and has permitted rational drug design to play a significantly greater role in a process which, in its early years, depended almost completely upon empirical and fortuitous observations.

Progress In Nucleic Acid Research And Molecular Biology

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Author :
language : en
Publisher: Academic Press
Release Date : 1990-11-09

Progress In Nucleic Acid Research And Molecular Biology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-11-09 with Medical categories.

Progress in Nucleic Acid Research and Molecular Biology

Genetic Consequences Of Nucleotide Pool Imbalance

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Author : Frederick De Serres
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Genetic Consequences Of Nucleotide Pool Imbalance written by Frederick De Serres and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

This book is concerned with the genetic consequences of nu cleotide pool imbalance. There are a number of ways in which this state can be achieved and the majority of papers in this volume de scribe the effects of nucleotide pool imbalance on DNA replication and repair, and the induction of gene mutations in various organisms. This book grew out of a Conference on "Genetic Consequences of Nu cleotide Pool Imbalance" which was held at the National Institute of Environmental Health Sciences on May 9-11, 1983. The Organizing Com mittee consisted of Drs. Diana Anderson (BIBRA), Robert Haynes (York University), Bernard Kunz (NIEHS), Barry Glickman (NIEHS), and Frederick J. de Serres (NIEHS), Chairman. The meeting was org- ized by the staff of the Office of the Associate Director for Genetics and was financed solely by the National Institute of Environmental Health Sciences. Frederick J. de Serres, Ph.D. Associate Director for Genetics v CONTENTS SECTION I. INTRODUCTION Molecular Mechanisms in Genetic Stability and Change: 1 The Role of Deoxyribonucleotide Pool Balance •••••• Robert H. Haynes SECTION II. NUCLEOTIDE METABOLISM 25 Metabolic Effects of Poly(ADP-ribose) Inhibitors •••••••• Kathryn M. Milam and James E. Cleaver Ribonucleotide Reductase and Deoxyribonucleotide 33 POQ 1 s ............................................ . Peter Reichard 47 Enzymatic Channeling of DNA Precursors •••••••••••••••••• Christopher K. Mathews A Possible Secondary Role for Thymine-Containing DNA 67 Precursors ....................................... . Robert J. Melamede and Susan S. Wallace Multiple Mechanisms of Adenosine Toxicity in an Adenosine Sensitive Mutant of Baby Hamster 103 Kidney (BHK) Cells............................... .

Cancer Treatment Reports

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Author :
language : en
Publisher:
Release Date : 1981

Cancer Treatment Reports written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Cancer categories.