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Early Life Environmental Exposure And Disease


Early Life Environmental Exposure And Disease
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Early Life Environmental Exposure And Disease


Early Life Environmental Exposure And Disease
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Author : Yankai Xia
language : en
Publisher: Springer Nature
Release Date : 2020-07-09

Early Life Environmental Exposure And Disease written by Yankai Xia and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-09 with Medical categories.


This book offers valuable insights into the latest concepts and findings from epidemiologic, clinical and basic studies in the burgeoning area of early-life environmental exposure and diseases. The book is divided into five parts, starting with an overview of environmental exposure measurement and evaluation, followed by a review of the effects of exposure to various substances like tobacco smoke, pesticides and metals as well as stress on offspring’s health. It then discusses the developmental origins of a range of childhood diseases that affect growth, neural development and the immune system, and highlights the importance of longitudinal studies that measure exposure at potentially sensitive time points during childhood. It also provides up-to-date evidence of the intergenerational/transgenerational effects of early-life environmental exposure, especially via genetic and epigenetic pathways. Allowing readers to gain a thorough understanding of the predominating aspects of early-life environmental exposure and diseases, the book also provides a basis for developing environmental and health policies that could have wide and long-term impacts on human health.



Textbook Of Children S Environmental Health


Textbook Of Children S Environmental Health
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Author : Philip J. Landrigan
language : en
Publisher:
Release Date : 2024

Textbook Of Children S Environmental Health written by Philip J. Landrigan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024 with categories.


"Children's Environmental Health is an academic discipline, a branch of pediatrics, that studies how environmental exposures in early life - chemical, physical, nutritional and social exposures - influence health, development and risk of disease in infancy, childhood and across the entire human lifespan. The focus of children's environmental health is on the discovery, diagnosis, treatment and prevention of diseases in children that are associated with harmful exposures in the environment. Children's environmental health also studies how positive environments protect children's health and nurture healthy growth and development. Children's environmental health is sometimes termed "environmental pediatrics""--



Child Health And The Environment


Child Health And The Environment
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Author : Donald T. Wigle
language : en
Publisher: Oxford University Press
Release Date : 2003-03-20

Child Health And The Environment written by Donald T. Wigle and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-20 with Medical categories.


This is the first textbook to focus on environmental threats to child health. It will interest professionals and graduate students in public health, pediatrics, environmental health, epidemiology, and toxicology. The first three chapters provide overviews of key children's environmental health issues as well as the role of environmental epidemiology and risk assessment in child health protection. Overarching themes are the susceptibility of the rapidly developing fetus and infant to environmental toxicants, the importance of modifying factors(e.g. poverty, genetic traits, nutrition), the role of health outcome and exposure monitoring, uncertainties surrounding environmental exposure limits, and the importance of timely intervention. Later chapters address the health effects of metals, PCBs, dioxins, pesticides, hormonally active agents, radiation, indoor and outdoor air pollution, and water contaminants. In analyzing potential environmental hazards, the author addresses both biologic and epidemiologic evidence, including the likelihood of causal relationships. Among the health outcomes he discusses are developmental, reproductive, and neurobehavioral effects, respiratory disease, cancer, and waterborne infectious diseases. These discussions cover environmental exposure sources/indicators, interventions, and standards, and conclude with a summary of calls for an improved science base to guide public health decisions and protect child health.



Environmental Epidemiology


Environmental Epidemiology
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Author : Rodolfo Saracci
language : en
Publisher: CRC Press
Release Date : 2019-06-04

Environmental Epidemiology written by Rodolfo Saracci and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-04 with Medical categories.


Published in 1996: Environmental Epidemiology: Exposure and Disease is a unique resource identifying priorities for public health research in selected areas of environmental epidemiology. Drawn from the proceedings of an international workshop on this topic, the book is a compilation of the specialized knowledge and opinions of environmental epidemiology experts. Organized by the Rome division of the World Health Organization (WHO) European Centre for Environment and Health, the goal of the 1993 workshop, Setting Priorities in Environmental Epidemiology, was to establish a consensus among the experts in the selected areas. The chapters in Environmental Epidemiology: Exposure and Disease cover environmental epidemiology from three different viewpoints: environmental exposures, major disease groups related to the environment, and epidemiological methodology. The environmental exposure categories examined for prioritizing are air contaminants, water contaminants, and ionizing and non-ionizing radiation exposure from human-caused disasters. .



Early Exposures To Hazardous Chemicals Pollution And Associations With Chronic Disease


Early Exposures To Hazardous Chemicals Pollution And Associations With Chronic Disease
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Author : Kathleen Cooper
language : en
Publisher:
Release Date : 2011

Early Exposures To Hazardous Chemicals Pollution And Associations With Chronic Disease written by Kathleen Cooper and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Chronic diseases categories.


This report is a product of a network to network collaboration among groups involved with the Canadian Partnership for Children's Health and Environment and the Ontario Chronic Disease Prevention Alliance (CPCHE and OCDPA) to provide a baseline for further collaboration. The central focus is a scoping review of evidence for associations between early life environmental exposures and the later development of several of the most common chronic diseases.



Environmental Neuroscience


Environmental Neuroscience
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2021-01-22

Environmental Neuroscience written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-22 with Medical categories.


Humans are potentially exposed to more than 80,000 toxic chemicals in the environment, yet their impacts on brain health and disease are not well understood. The sheer number of these chemicals has overwhelmed the ability to determine their individual toxicity, much less potential interactive effects. Early life exposures to chemicals can have permanent consequences for neurodevelopment and for neurodegeneration in later life. Toxic effects resulting from chemical exposure can interact with other risk factors such as prenatal stress, and persistence of some chemicals in the brain over time may result in cumulative toxicity. Because neurodevelopmental and neurodegenerative disorders - such as attention-deficit hyperactivity disorder and Parkinson's disease - cannot be fully explained by genetic risk factors alone, understanding the role of individual environmental chemical exposures is critical. On June 25, 2020, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders hosted a workshop to lay the foundation for future advances in environmental neuroscience. The workshop was designed to explore new opportunities to bridge the gap between what is known about the genetic contribution to brain disorders and what is known, and not known, about the contribution of environmental influences, as well as to discuss what is known about how genetic and environmental factors interact. This publication summarizes the presentation and discussion of the workshop.



The Promise Of Adolescence


The Promise Of Adolescence
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2019-07-26

The Promise Of Adolescence written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-26 with Social Science categories.


Adolescenceâ€"beginning with the onset of puberty and ending in the mid-20sâ€"is a critical period of development during which key areas of the brain mature and develop. These changes in brain structure, function, and connectivity mark adolescence as a period of opportunity to discover new vistas, to form relationships with peers and adults, and to explore one's developing identity. It is also a period of resilience that can ameliorate childhood setbacks and set the stage for a thriving trajectory over the life course. Because adolescents comprise nearly one-fourth of the entire U.S. population, the nation needs policies and practices that will better leverage these developmental opportunities to harness the promise of adolescenceâ€"rather than focusing myopically on containing its risks. This report examines the neurobiological and socio-behavioral science of adolescent development and outlines how this knowledge can be applied, both to promote adolescent well-being, resilience, and development, and to rectify structural barriers and inequalities in opportunity, enabling all adolescents to flourish.



Children S Health And Environment


Children S Health And Environment
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Author : European Environment Agency
language : en
Publisher:
Release Date : 2002

Children S Health And Environment written by European Environment Agency and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Child health services categories.


The protection of children's health from environmental hazards is crucial to achievement of sustainable development, as failure to focus on this problem will amplify not only the health burden of today's children but also that of future generations. This report examines available evidence of health problems and associated environmental factors, including asthma and other respiratory diseases, neurodevelopmental disorders, cancer and birth defects. It also considers the concept of environmental justice, as well providing an overview of related research and policy issues. The report is based on background documents prepared for the Third Ministerial Conference on Environment and Health, held in London in 1999.



Prenatal Exposure To Environmental Contaminants And Newborn Immune System Biomarkers


Prenatal Exposure To Environmental Contaminants And Newborn Immune System Biomarkers
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Author : Jillian Ashley-Martin
language : en
Publisher:
Release Date : 2014

Prenatal Exposure To Environmental Contaminants And Newborn Immune System Biomarkers written by Jillian Ashley-Martin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.


Allergic disease are among the most common chronic childhood disease and a leading cause of hospitalization. Exposure to certain environmental contaminants has been hypothesized to be a risk factor for childhood allergies and asthma. Scientific understanding regarding the effect of prenatal contaminant exposure on fetal immune system development and subsequent susceptibility to allergic diseases is limited. Elevated levels of immunoglobulin E (IgE) are a hallmark sign of an allergic response. Elevated levels of interleukin-33 (IL-33) and thymic stromal lymphopoietin (TSLP) are implicated in inflammatory responses and early life manifestations of allergic disease but have not been measured in neonates. The objectives of this research were to 1) assess the levels of, correlation among and predictors of IgE, IL-33 and TSLP in umbilical cord blood and 2) determine the association between prenatal exposure to environmental contaminants and elevated levels of IgE, TSLP and IL-33. Concentrations of metals, phthalates, bisphenol A, pesticides, and polychlorinated biphenyls were measured in maternal urine, blood or plasma. IgE, IL-33 and TSLP were measured in umbilical cord blood samples. Data were obtained from the Maternal-Infant Research on Environmental Chemicals (MIREC) study, a Canadian cohort study of 2,001 women recruited from 10 sites between 2008 and 2011. TSLP and IL-33 were highly correlated with each other but neither was strongly correlated with IgE. Elevated levels of TSLP and IL-33 were significantly associated with maternal characteristics indicative of inflammatory responses. None of the environmental contaminants were associated with elevated immune system biomarker levels. These findings support the mechanistic hypothesis that IL-33 and TSLP are both operational in early life inflammatory pathways. Determination of whether the observed absence of environmental exposure-induced immunotoxicity persists into childhood requires follow-up in a cohort of children.



Children S Environmental Health Proceedings Of A Workshop


Children S Environmental Health Proceedings Of A Workshop
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Author : National Academies Of Sciences Engineeri
language : en
Publisher: National Academies Press
Release Date : 2023-10-19

Children S Environmental Health Proceedings Of A Workshop written by National Academies Of Sciences Engineeri and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-19 with Medical categories.