Eicosanoids And The Gastrointestinal Tract
DOWNLOAD
Download Eicosanoids And The Gastrointestinal Tract PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Eicosanoids And The Gastrointestinal Tract book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Eicosanoids And The Gastrointestinal Tract
DOWNLOAD
Author : K. Hillier
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Eicosanoids And The Gastrointestinal Tract written by K. Hillier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The original series, Advances in Prostaglandin Research, edited by Sultan M. M. Karim, was published by MTP Press in three volumes in 1975 and 1976. A glance at those books illustrates the progress that has been made since then. The thromboxanes were mentioned twice (first publication 1975) and prostacyclin not once (first publication 1976); leukotrienes were only on the horizon. The amazing generation of research data in the last 10-15 years has given new, broad insights into many areas, including asthma, inflammation, renaL cardiovascular and gastrointestinal diseases and in reproduction, and has led in some instances to real clinical benefit. This series,AdvancesinEicosanoidResearch, reflects the current understanding of prostaglandins, thromboxanes and leukotrienes. The aim is to provide an introductory background to each topic and the most up-to-date information available. Although each book stands alone, the eicosanoids cut across many boundaries in their basic actions; selected chapters from each book in the Series will provide illuminating and productive information for all readers which will advance their education and research. In the production of this series, I must acknowledge with pleasure my collaboration with editors and authors and the patient endeavours of Dr. Michael Brewis and the staff at MTP Press.
Prostaglandins And Leukotrienes In Gastrointestinal Diseases
DOWNLOAD
Author : W. Domschke
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Prostaglandins And Leukotrienes In Gastrointestinal Diseases written by W. Domschke and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In OCtober 1986, recognized authorities from a variety of disciplines met in Lisbon, Portugal, to review recent knowledge on eicosanoids - i. e., prostaglandins, throm boxane A , and leukotrienes - and their role in gastrointestinal diseases. 2 Briefly, in the stomach endogenous as well as exogenous prostaglandins may mediate cytoprotective actions in that they stimulate gastric mucus production, bicar bonate secretion and cellular regeneration while providing adequate mucosal blood flow. In contrast, thromboxane A2 by vasoconstriction may act as an ulcerogenic substance. Diarrheal states may be associated with prostaglandins of types E and F as they are capable to enhance intestinal water and electrolyte secretions. In chronic in flammatory bowel disease, mucosal synthesis of leukotrienes was found to be increased more markedly than that of prostaglandins suggesting that leukotrienes may have a major part in the pathogenesis of that disease. In this volume, which is an elaborated collection of the papers given on occasion of the above-mentioned symposium, the facts and problems associated with prostanoid substances are dealt with in four sections on 1. biochemistry, biology and pharmacology of eicosanoids, 2. physiologic and pathophysiologic aspects, 3. established therapeutic implications, and 4. treatment perspectives. We believe that the publication of these contributions by leading workers in the given fields provides a comprehensive and up-to-date appraisal of the role of eicosanoids in gastrointestinal diseases, and it is hoped that this volume will be of value to both basic scientists and practicing clinicians.
Prostaglandins And Leukotrienes In Gastrointestinal Diseases
DOWNLOAD
Author : Wolfram Domschke
language : en
Publisher: Springer Verlag
Release Date : 1988
Prostaglandins And Leukotrienes In Gastrointestinal Diseases written by Wolfram Domschke and has been published by Springer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.
Immunopharmacology Of The Gastrointestinal System
DOWNLOAD
Author : John L. Wallace
language : en
Publisher: London ; Toronto : Academic Press
Release Date : 1993
Immunopharmacology Of The Gastrointestinal System written by John L. Wallace and has been published by London ; Toronto : Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
Diseases of the digestive system have a higher morbidity rate than any other group of disorder. There is a growing body of evidence that the immune system participates in the pathogenesis of a wide range of these diseases, including peptic ulcer disease and the gastropathy induced by nonsteroidal anti-inflammatory drugs (NSAIDS). For these reasons, efforts to develop novel therapies for digestive diseases are increasingly focused on the immune system. This volume reviews the immunopharmacology of the gastrointestinal tract at four distinct levels: Immunomodulation at a cellular level Cellular targers for immunomodulating drugs Specific classes of inflammatory mediators Utility and mechanisms of action of glucocorticoids in the treatment of diseases of the gastrointestinal tract.
Immunopharmacology Of The Gastrointestinal System
DOWNLOAD
Author : John L. Wallace
language : en
Publisher: Academic Press
Release Date : 1993-03-01
Immunopharmacology Of The Gastrointestinal System written by John L. Wallace and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-03-01 with Medical categories.
Diseases of the digestive system have a higher morbidity rate than any other group of disorder. There is a growing body of evidence that the immune system participates in the pathogenesis of a wide range of these diseases, including peptic ulcer disease and the gastropathy induced by nonsteroidal anti-inflammatory drugs (NSAIDS). For these reasons, efforts to develop novel therapies for digestive diseases are increasingly focused on the immune system. This volume reviews the immunopharmacology of the gastrointestinal tract at four distinct levels: Immunomodulation at a cellular level Cellular targers for immunomodulating drugs Specific classes of inflammatory mediators Utility and mechanisms of action of glucocorticoids in the treatment of diseases of the gastrointestinal tract.
The Eicosanoids
DOWNLOAD
Author : Peter Curtis-Prior
language : en
Publisher: John Wiley & Sons
Release Date : 2004-07-16
The Eicosanoids written by Peter Curtis-Prior and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-07-16 with Medical categories.
This comprehensive reference work, updated from the first edition, brings together the knowledge and expertise of contributors from around the world. It includes new topics such as prostaglandin synthetase enzyme, new synthetic eicosanoids, innovative analytical methods, the influence of cytokines in the regulation of synthesis and actions, newer eicosanoids that influence the cardiovascular system, and newly discovered roles in reproduction and interactions with nitric oxide. This book satisfies a surge of interest in prostaglandins—NSAIDS (e.g. aspirin) are the biggest selling drugs of all time, and the field has been refreshed by the advent of new types (selective COX-2 inhibitors, anti-leukotiene drugs).
Aspirin And Related Drugs
DOWNLOAD
Author : Kim D. Rainsford
language : en
Publisher: CRC Press
Release Date : 2004-10-28
Aspirin And Related Drugs written by Kim D. Rainsford and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-28 with Health & Fitness categories.
Reviewing over a century of aspirin research and use, Aspirin and Related Drugs provides a comprehensive source of information on the history, chemistry, absorption in the body, therapeutic effects, toxicology, elimination, and future uses of aspirin. Highlighting the historical evolution of the salicylates and the commercial development of
Drug Development
DOWNLOAD
Author : Timothy S. Gaginella
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-09-01
Drug Development written by Timothy S. Gaginella and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-09-01 with Medical categories.
The application of molecular techniques to gastroenterology continues to yield important advances in the development of drugs to treat gastrointestinal disorders. Important new drugs have emerged through the collaborative and complementary efforts of basic scientists, clinicians, and clinical researchers in academia and the pharmaceutical industry. The challenge has been exciting, with a few surprises along the way. Consider peptic ulcer disease as an example. The discovery of H receptors and the availability of potent and 2 selective H-receptor antagonists signaled the beginning of a new era 2 in the treatment of gastric hypersecretory states and peptic ulcers. Introduction of proton pump inhibitors offered another therapeutic option. Though H-receptor antagonists and proton pump inhibitors 2 are important and useful drugs, the discovery of the link between H. pylori infection and peptic ulcer disease has led to even more effective pharmacotherapeutic regimens. Our intent in Drug Development: Molecular Targets for GI Diseases is to bring together hands-on experts to review promising areas of gastrointestinal pharmacology. The contemporary topics covered, from a mechanistic viewpoint, are relevant to gastrointestinal inflammation and motility disorders. Authoritative opinions are offered on both future research directions and potential applications for new therapies.
Encyclopedia Of Cancer
DOWNLOAD
Author : Manfred Schwab
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-09-23
Encyclopedia Of Cancer written by Manfred Schwab and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-23 with Medical categories.
This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.
Drugs Affecting Leukotrienes And Other Eicosanoid Pathways
DOWNLOAD
Author : G. Velo
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Drugs Affecting Leukotrienes And Other Eicosanoid Pathways written by G. Velo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.