Epigenetic Variants Of The Human Skull
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Epigenetic Variants Of The Human Skull
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Author : Gertrud Hauser
language : en
Publisher: E. Schweizerbartsche Verlagsbuchhandlung
Release Date : 1989
Epigenetic Variants Of The Human Skull written by Gertrud Hauser and has been published by E. Schweizerbartsche Verlagsbuchhandlung this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Anthropology categories.
With this atlas on ``Epigenetic Variants of the Human Skull'' Hauser and De Stefano produced a much required reference work on minor cranial variants. These traits were named epigenetic since they may be seen as products of genetically determined growth processes of other tissues (e.g. nerves, vessels and muscles) affecting bone information. Consequently they may undergo modification during ontogeny in the presence of modifying genes or relevant environmental conditions and generally show variable degrees of expression. Many of these variants had already been described mainly as mere skeletal anomalies. Renewed interest resulted when crosses between inbred strains of mice established the potential value of minor skeletal variants in genetic studies. But in the light of the new experiences one may ask if the characters selected were the most useful for their purpose? Are they easy to identify, and are their definitions rigorous and unambigous ? What is known about their embryology and development, their genetic control? Was their categorisation adequate? Are they of any general medical, forensic or surgical relevance? What is the extent of intrapopulation variation in incidence ? How do they vary between populations ? This atlas endeavores to answer such questions and to serve as a reference text. The entry of each of the 84 characters summarises its nomenclature, gross anatomy, function, embryology and growth, genetics, medical relevance, sex differences, symmetry (if the character is bilateral), laterality or side preference, age variation, association with other traits, and methods of scoring (the traditional as well as that now proposed). For some traits new results are given applying the proposed methods to male adult skulls of recorded age and origin as well as the frequencies of the variants investigated by traditional methods in a selection of the populations of the world from the literature. The high quality photographs and the overlays (in colour) on the five main views of the skull illustrate each character clearly, better than any verbal definition. The collaboration of 13 international scientists specialised in different fields emphasizes the high quality of this book, and its usefulness for many disciplines as Human Biology and related sciences, Human Genetics, Forensic Medicine, Radiology, Surgery etc. A most extensive bibliography and a synoptical index conclude this reference work which confronts specialists of Human Biology, Anthropology, Medicine, Biology and Genetics with a fascinating problem but is also most useful and comprehensible for students.
Epigenetics Brain And Behavior
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Author : Paolo Sassone Corsi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-08-28
Epigenetics Brain And Behavior written by Paolo Sassone Corsi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-28 with Medical categories.
What lies at the heart of neuronal plasticity? Accumulating evidence points to epigenetics. This word originally indicated potentially heritable modifications in gene expression that do not involve changes in DNA sequence. Today this definition is much less strict, and epigenetic control is thought to include DNA methylation, histone modifications, histone variants, microRNA metabolic pathways and non-histone proteins modifications. Thus, while neuronal plasticity is rightly thought to be intimately associated to genomic control, it is critical to appreciate that there is much more to the genome than DNA sequence. Recent years have seen spectacular advances in the field of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigenetic regulation to brain functions has been accumulating. Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. A variety of studies have centered on the molecular mechanisms implicated in epigenetic control and how these may operate in concert. It will be critical to unravel how specificity is achieved. Importantly, specific modifications seem to mediate both developmental processes and adult brain functions, such as synaptic plasticity and memory. Many aspects of the research in neurosciences and endocrinology during the upcoming decade will be dominated by the deciphering of epigenetic control. This book constitutes a compendium of the most updated views in the field.
Human Epigenetics How Science Works
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Author : Carsten Carlberg
language : en
Publisher: Springer Nature
Release Date : 2019-09-24
Human Epigenetics How Science Works written by Carsten Carlberg and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-24 with Medical categories.
The view “It’s all in our genes and we cannot change it” developed in the past 150 years since Gregor Mendel’s experiments with flowering pea plants. However, there is a special form of genetics, referred to as epigenetics, which does not involve any change of our genes but regulates how and when they are used. In the cell nucleus our genes are packed into chromatin, which is a complex of histone proteins and genomic DNA, representing the molecular basis of epigenetics. Our environment and lifestyle decisions influence the epigenetics of our cells and organs, i.e. epigenetics changes dynamically throughout our whole life. Thus, we have the chance to change our epigenetics in a positive as well as negative way and present the onset of diseases, such a type 2 diabetes or cancer. This textbook provides a molecular explanation how our genome is connected with environmental signals. It outlines that epigenetic programming is a learning process that results in epigenetic memory in each of the cells of our body. The central importance of epigenetics during embryogenesis and cellular differentiation as well as in the process of aging and the risk for the development of cancer are discussed. Moreover, the role of the epigenome as a molecular storage of cellular events not only in the brain but also in metabolic organs and in the immune system is described. The book represents an updated but simplified version of our textbook “Human Epigenomics” (ISBN 978-981-10-7614-8). The first five chapters explain the molecular basis of epigenetics, while the following seven chapters provide examples for the impact of epigenetics in human health and disease.
Atlas Of Developmental Field Anomalies Of The Human Skeleton
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Author : Ethne Barnes
language : en
Publisher: John Wiley & Sons
Release Date : 2012-09-25
Atlas Of Developmental Field Anomalies Of The Human Skeleton written by Ethne Barnes and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-25 with Science categories.
Written by one of the most consulted authorities on the subject, Atlas of Developmental Field Anomalies of the Human Skeleton is the pre-eminent resource for developmental defects of the skeleton. This guide focuses on localized bone structures utilizing the morphogenetic approach that addresses the origins of variability within specific developmental fields during embryonic development. Drawings and photographs make up most of the text, forming a picture atlas with descriptive text for each group of illustrations. Each section and subdivision is accompanied by brief discussions and drawings of morphogenetic development.
Asymptomatic Osseous Variations Of The Postcranial Human Skeleton
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Author : Emeline Verna
language : en
Publisher: John Wiley & Sons
Release Date : 2023-08-29
Asymptomatic Osseous Variations Of The Postcranial Human Skeleton written by Emeline Verna and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-29 with Science categories.
Since ancient times, asymptomatic bone variations have been studied in many different disciplines. In radiology, for example, they enable the differentiation of the typical from the anomalous, but in biological anthropology they are especially useful in answering questions about humans and their diachronic and synchronic variability. This book provides an easily accessible presentation of the osseous variations of the postcranial skeleton (from the spine to the feet), which are sometimes poorly understood by the scientific community. These variations are examined one by one, with definitions, population frequencies and complete illustrations given for each. Asymptomatic Osseous Variations of the Postcranial Human Skeleton is intended as a comprehensive reference manual for further research on these types of skeletal variations.
Atlas Of Human Cranial Macromorphoscopic Traits
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Author : Joseph T. Hefner
language : en
Publisher: Academic Press
Release Date : 2018-08-02
Atlas Of Human Cranial Macromorphoscopic Traits written by Joseph T. Hefner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-02 with Law categories.
Atlas of Human Cranial Macromorphoscopic Traits synthesizes macromorphoscopic traits and their analysis in an accessible manner, providing detailed descriptions and examples of the various character state manifestations intended for use in classrooms, laboratories, and in the field. The volume begins with an outline of the macromorphoscopic dataset, its history, recent modifications to the historical approach, and recent technological and analytical advances. Additional sections cover Nomenclature, Gross Anatomy, Function, Methodology, Line Drawings, Detailed Definitions, Multiple High-resolution Photographs, and Population Variation Data from the Macromorphoscopic Databank (MaMD). The volume concludes with a chapter outlining the statistical analysis of macromorphoscopic data and a summary of the computer programs and reference databases available to forensic anthropologists for the analysis of these data. Provides detailed descriptions, illustrations and high-resolution images of various character state manifestations of seventeen macromorphoscopic traits Applies to both forensic and bioarcheological research Written by the foremost expert on macromorphoscopic trait analysis and estimation of ancestry in forensic anthropology
Bergman S Comprehensive Encyclopedia Of Human Anatomic Variation
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Author : R. Shane Tubbs
language : en
Publisher: John Wiley & Sons
Release Date : 2016-04-25
Bergman S Comprehensive Encyclopedia Of Human Anatomic Variation written by R. Shane Tubbs and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-25 with Science categories.
Building on the strength of the previous two editions, Bergman's Comprehensive Encyclopedia of Human Anatomic Variation is the third installment of the classic human anatomical reference launched by Dr. Ronald Bergman. With both new and updated entries, and now illustrated in full color, the encyclopedia provides an even more comprehensive reference on human variation for anatomists, anthropologists, physicians, surgeons, medical personnel, and all students of anatomy. Developed by a team of editors with extensive records publishing on both human variation and normal human anatomy, Bergman's Comprehensive Encyclopedia of Human Anatomic Variation is the long awaited update to this classic reference.
The Evolution Of The Human Head
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Author : Daniel Lieberman
language : en
Publisher: Harvard University Press
Release Date : 2011-01-03
The Evolution Of The Human Head written by Daniel Lieberman and has been published by Harvard University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-03 with MEDICAL categories.
Exhaustively researched and years in the making, this innovative book documents how the many components of the head function, how they evolved since we diverged from the apes, and how they interact in diverse ways both functionally and developmentally, causing them to be highly integrated. This integration not only permits the head's many units to accommodate each other as they grow and work, but also facilitates evolutionary change. Lieberman shows how, when, and why the major transformations evident in the evolution of the human head occurred. The special way the head is integrated, Lieberman argues, made it possible for a few developmental shifts to have had widespread effects on craniofacial growth, yet still permit the head to function exquisitely. --
Biological Anthropology Of The Human Skeleton
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Author : M. Anne Katzenberg
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-23
Biological Anthropology Of The Human Skeleton written by M. Anne Katzenberg and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-23 with Social Science categories.
"This book is virtually required reading for biological anthropologists and will be a useful, up-to-date primer on osteological analyses for a wider audience." —The Quarterly Review of Biology, March 2009 "... a comprehensive guide to the ever-changing discipline of physical anthropology... provides an in depth introduction to human skeletal biology. The structure of the book makes it easy for the reader to follow the progression of the field of human skeletal biology." —PaleoAnthropology, 2009 Issue The First Edition of Biological Anthropology of the Human Skeleton is the market-leading reference and textbook on the scientific analysis of human skeletal remains recovered from archaeological sites. Now, featuring scores of new or thoroughly revised content, this Second Edition provides the most comprehensive and up-to-date coverage of the topic available. Like the previous edition, this Second Edition is organized into five parts with contributing chapters written by experts in the field of human skeletal biology: Part One covers theory and application; Part Two discusses morphological analyses of bone, teeth, and age changes; Part Three reviews prehistoric health and disease; Part Four examines chemical and genetic analysis of hard tissues; and Part Five closes with coverage of quantitative methods and population studies. Each chapter includes a review of recent studies, descriptions of analytical techniques and underlying assumptions, theory, methodological advances, and speculation about future research. New or thoroughly revised content includes: Techniques in the analysis of human skeletal and dental remains Extensive coverage of new technologies, including modern morphometric techniques Advances in the field of forensic anthropology Enhanced discussion of ethical terms regarding the study of aboriginal peoples' remains where those people are no longer the dominant culture This book serves as an indispensable research guide to biological anthropologists, osteologists, paleoanthropologists, and archaeologists. Now with a stronger focus on teaching complex material to students, this revised edition provides enhanced case studies and discussions for future directions, making it an invaluable textbook for advanced undergraduates and graduate students in biological anthropology and forensic anthropology programs.
The Neurobiological Basis Of Suicide
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Author : Yogesh Dwivedi
language : en
Publisher: CRC Press
Release Date : 2012-06-25
The Neurobiological Basis Of Suicide written by Yogesh Dwivedi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-25 with Medical categories.
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.