Estrat Gias De Sa De Da Fam Lia
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Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
The Philosophy Of Palliative Care
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Author : Fiona Randall
language : en
Publisher: Oxford University Press
Release Date : 2006-02-23
The Philosophy Of Palliative Care written by Fiona Randall and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-02-23 with Medical categories.
The philosophy of palliative care has long remained undisputed by health care professionals and philosophers. This unique book reviews the ethical problems inherent within care of the terminally ill. It suggests a new philosophy statement that could improve clinical care and take the specialty forward.
Business Ethics
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Author : Alejo José G. Sison
language : en
Publisher: Routledge
Release Date : 2018-03-09
Business Ethics written by Alejo José G. Sison and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-09 with Business & Economics categories.
Can business activities and decisions be virtuous? This is the first business ethics textbook to take a virtue ethics approach. It explains how virtue ethics compares with alternative approaches to business ethics, such as utilitarianism and deontology, and argues that virtue ethics best serves the common good of society. Looking across the whole spectrum of business—including finance, governance, leadership, marketing and production—each chapter presents the theory of virtue ethics and supports students’ learning with chapter objectives, in-depth interviews with professionals and real-life case studies from a wide range of countries. Business Ethics: A Virtue Ethics and Common Good Approach is a valuable text for advanced undergraduates and masters-level students on business ethics courses.
Female Sexual Pain Disorders
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Author : Andrew T. Goldstein
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-23
Female Sexual Pain Disorders written by Andrew T. Goldstein and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-23 with Medical categories.
First book devoted to the diagnosis and treatment of sexual pain in women Female Sexual Pain Disorders is a remarkable fusion of clinical and scientific knowledge that will empower women’s healthcare professionals to help their patients in overcoming this common debilitating disorder. Based on the highest level research, it provides state-of-the-art practical guidance that will help you to: Evaluate and distinguish the causes of sexual pain in women Differentiate the many forms of sexual pain Implement multidisciplinary treatments Distilling the experience of world leaders across many clinical, therapeutic and scientific disciplines, with an array of algorithms and diagnostic tools, Female Sexual Pain Disorders is your ideal companion for treating the many millions of women who suffer from this disorder worldwide. All proceeds from this book are being donated to the International Society for the Study of Women’s Sexual Health (ISSWSH).
Toward A Methodology Of Naturalistic Inquiry In Educational Evaluation
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Author : Egon G. Guba
language : en
Publisher:
Release Date : 1978
Toward A Methodology Of Naturalistic Inquiry In Educational Evaluation written by Egon G. Guba and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Curriculum evaluation categories.
Welfare Regimes And The Experience Of Unemployment In Europe
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Author : Duncan Gallie
language : en
Publisher: OUP Oxford
Release Date : 2000-05-25
Welfare Regimes And The Experience Of Unemployment In Europe written by Duncan Gallie and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-05-25 with Political Science categories.
The book is the first major study to examine the implications of differences in welfare regimes for the experience of unemployment in Europe. It is concerned with three central questions about the way such regimes affect the experience of unemployment. The first is how far they protect the quality of life of unemployed people with respect to living standards and the experience of financial hardship. The second is their role in mediating the impact of unemployment on the individual's longer-term position in the labour market, addressing the issue of how far they help to prevent progressive marginalization from the employment structure as a result of motivational change, skill loss or the growth of discriminatory barriers. The third is how far such regimes mediate the impact of unemployment on social integration in the community, for instance with respect to the maintenance (or rupture) of social networks and the degree of psychological distress experienced by the unemployed. The book is the product of a major cross-cultural research programme, funded by the European Union (TSER), bringing together teams from eight countries. The emphasis has been on rigorous comparison rather than the all-too-frequent separate country analyses, which usually provide data which differs in format from one country to another. In addition to a systematic comparison of national data sources, it has been able to make use of a new important data source (the European Community Household Panel) produced by Eurostat which provides directly comparable information for all EU countries. The study shows that institutional and cultural differences have vital implications for the experience of unemployment. While welfare policies affect in an important way the pervasiveness of poverty, it is above all the patterns of family structure and the culture of sociability in a society that affect vulnerability to social isolation. The book concludes by developing a new perspective for understanding the risk of social exclusion.
Towards A Lexicogrammar Of Mekeo
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Author : Alan A. Jones
language : en
Publisher: Pacific Linguistics Research School of Pacific and Asian Stu
Release Date : 1998
Towards A Lexicogrammar Of Mekeo written by Alan A. Jones and has been published by Pacific Linguistics Research School of Pacific and Asian Stu this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Foreign Language Study categories.
The Family Business
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Author : Fred Neubauer
language : en
Publisher: Springer
Release Date : 2016-07-27
The Family Business written by Fred Neubauer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-27 with Business & Economics categories.
The family business has a far reaching influence on economies throughout the world. No other type of business has driven economic development in the same way and today, in almost all countries, family businesses including such giants as Ford, Levi Strauss, L'Oréal and Ferrero are the source of more than half of the Gross National Product (GNP) and employment. As a result of their prominence the question of how they are governed, controlled and accounted for is crucial not only for the owning families, but also for the societies in which these companies operate. The Family Business considers: · How to define a family-controlled business and the significance of this form of privately-held enterprise. · Governance systems in the context of the family business. · How a board of outsiders can add value to the typical family business. · How to handle the classical tensions between family and board and between family and management on the other. · How to gain effective and efficient control at the highest level. The answer to these questions and others is given by providing a large number of examples of internationally active family businesses and from the authors teaching and research into this area. Sustainability is the key concern to the family business and this book breaks new ground in showing how they can successfully live on to the next generation.
Unbending Gender
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Author : Joan Williams
language : en
Publisher: Oxford University Press
Release Date : 2001-09-13
Unbending Gender written by Joan Williams and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-09-13 with Law categories.
In Unbending Gender, Joan Williams takes a hard look at the state of feminism in America. Concerned by what she finds--young women who flatly refuse to identify themselves as feminists and working-class and minority women who feel the movement hasn't addressed the issues that dominate their daily lives--she outlines a new vision of feminism that calls for workplaces focused on the needs of families and, in divorce cases, recognition of the value of family work and its impact on women's earning power.Williams shows that workplaces are designed around men's bodies and life patterns in ways that discriminate against women, and that the work/family system that results is terrible for men, worse for women, and worst of all for children. She proposes a set of practical policies and legal initiatives to reorganize the two realms of work in employment and households--so that men and women can lead healthier and more productive personal and work lives. Williams introduces a new 'reconstructive' feminism that places class, race, and gender conflicts among women at center stage. Her solution is an inclusive, family-friendly feminism that supports both mothers and fathers as caregivers and as workers.
Sources Of Medical Technology
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 1995-01-01
Sources Of Medical Technology written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-01-01 with Medical categories.
Evidence suggests that medical innovation is becoming increasingly dependent on interdisciplinary research and on the crossing of institutional boundaries. This volume focuses on the conditions governing the supply of new medical technologies and suggest that the boundaries between disciplines, institutions, and the private and public sectors have been redrawn and reshaped. Individual essays explore the nature, organization, and management of interdisciplinary R&D in medicine; the introduction into clinical practice of the laser, endoscopic innovations, cochlear implantation, cardiovascular imaging technologies, and synthetic insulin; the division of innovating labor in biotechnology; the government- industry-university interface; perspectives on industrial R&D management; and the growing intertwining of the public and proprietary in medical technology.