Exploring The Ethics Of Organ Farming Interspecies Chimera An Overview
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Exploring The Ethics Of Organ Farming Interspecies Chimera An Overview
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Author : Dr. Hakim Saboowala
language : en
Publisher: Dr.Hakim Saboowala
Release Date : 2020-04-28
Exploring The Ethics Of Organ Farming Interspecies Chimera An Overview written by Dr. Hakim Saboowala and has been published by Dr.Hakim Saboowala this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-28 with Medical categories.
Exploring the Ethics of Organ Farming & Interspecies Chimera. An Overview. An attempt has been made in this overview to examine the ethical issues surrounding human-animal chimeras and their use in the production of organs for transplantation. Currently, there is a prodigious backlog of transplants in the United States. · The median wait time for an organ transplant is almost 5 years, and about 20 people die waiting on the transplant list every day. o This crisis has necessitated the development of new strategies to acquire organs for transplantation. Among these advances is the prospect of growing a custom organ for a recipient using chimeras. Chimeras are organisms made up of two genetically distinct types of cells. Chimerization can occur within a single species or between two different species. · The latter type has garnered interest among scientists as a possible method for generating organs suitable for human transplantation. The proposed strategy is to create a chimera from a non-human animal embryo, usually a: · pig, and · human stem cells. Eventually, after the chimera reaches adulthood, the stem cell donor will receive a transplant with a new, humanoid organ from the chimera. Naturally, crossing species and sacrificing animal lives for organ farming comes with some ethical baggage, but chimera research has been prominent for several decades and foretells a bright future. An effort has been made in this E-Booklet to inculcate medicos in the subject of Chimera Research, particularly how it pertains to organ transplantation, and spark healthy debate surrounding the ethics of this medical advance. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London).
Current And Future Reproductive Technologies And World Food Production
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Author : G. Cliff Lamb
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-29
Current And Future Reproductive Technologies And World Food Production written by G. Cliff Lamb and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-29 with Science categories.
This book addresses the impacts of current and future reproductive technologies on our world food production and provides a significant contribution to the importance of research in the area of reproductive physiology that has never been compiled before. It would provide a unique opportunity to separate the impacts of how reproductive technologies have affected different species and their contributions to food production. Lastly, no publication has been compiled that demonstrates the relationship between developments in reproductive management tools and food production that may be used a reference for scientists in addressing future research areas. During the past 50 years assisted reproductive technologies have been developed and refined to increase the number and quality of offspring from genetically superior farm animal livestock species. Artificial insemination (AI), estrous synchronization and fixed-time AI, semen and embryo cryopreservation, multiple ovulation and embryo transfer (MOET), in vitro fertilization, sex determination of sperm or embryos, and nuclear transfer are technologies that are used to enhance the production efficiency of livestock species.
Chimera Research
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Author : Insoo Hyun
language : en
Publisher: Humana
Release Date : 2020-08-14
Chimera Research written by Insoo Hyun and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-14 with Science categories.
This volume addresses challenging new questions surrounding stem cell-based chimera research. This book is organized into three parts: Part One provides readers with a summary of different human donor cell types. The chapters in this section discuss ways to evaluate new types of pluripotent stem cells; the derivation of naïve and primed pluripotent stem cells from mouse preimplantation embryos; and the ethical and regulatory complexities of informed consent for the procurement of somatic cells. Part Two discusses methods for generating chimeras. The chapters here look at chick models and human-chick organizer grafts; generating human-pig interspecies chimeras; and techniques for transplanting mouse neural stem cells into a mouse disease model for stroke. Part Three concludes the book with a look at ongoing ethical controversies and new scientific directions. Chapters in this part cover the ethics of crossing the xenobarrier; animal welfare; experimentation with spermatogonial stem cells; and cautious approaches to human-monkey chimera studies to further understand complex human brain disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Chimera Research: Methods and Protocols is a valuable resource for scientists interesting in using chimeras as a research tool while also taking into consideration their complex ethical scopes.
Xenotransplantation
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 1996-07-12
Xenotransplantation written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-07-12 with Medical categories.
Xenotransplantation involves the transplantation of cells, tissues, and whole organs from one species to another. Interest in animal-to-human xenotransplants has been spurred by the continuing shortage of donated human organs and by advances in knowledge concerning the biology of organ and tissue rejection. The scientific advances and promise, however, raise complex questions that must be addressed. This book considers the scientific and medical feasibility of xenotransplantation and explores the ethical and public policy issues surrounding the possibility of renewed clinical trials. The volume focuses on the science base of xenotransplantation, public health risks of infectious disease transmission, and ethical and public policy issues, including the views of patients and their families.
Guidelines For Human Embryonic Stem Cell Research
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2005-09-15
Guidelines For Human Embryonic Stem Cell Research written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-15 with Medical categories.
Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research.
Guidelines For The Care And Use Of Mammals In Neuroscience And Behavioral Research
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2003-08-22
Guidelines For The Care And Use Of Mammals In Neuroscience And Behavioral Research written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-08-22 with Science categories.
Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
The Ethics Of Research Involving Animals
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Author :
language : en
Publisher:
Release Date : 2005-01-01
The Ethics Of Research Involving Animals written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-01 with Animal experimentation categories.
A report of the Nuffield Council on Bioethics working party investigating the ethical issues of research involving animals.
Human Genome Editing
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2017-08-13
Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-13 with Medical categories.
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
Stem Cells
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Author : Ariff Bongso
language : en
Publisher: World Scientific
Release Date : 2011
Stem Cells written by Ariff Bongso and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
Stem cell biology has drawn tremendous interest in recent years as it promises cures for a variety of incurable diseases. This book deals with the basic and clinical aspects of stem cell research and involves work on the full spectrum of stem cells isolated today. It also covers the conversion of stem cell types into a variety of useful tissues which may be used in the future for transplantation therapy. It is thus aimed at undergraduates, postgraduates, scientists, embryologists, doctors, tissue engineers and anyone who wishes to gain some insight into stem cell biology. This book is important as it is comprehensive and covers all aspects of stem cell biology, from basic research to clinical applications. It will have 33 chapters written by renowned stem cell scientists worldwide. It will be up-to-date and all the chapters include self-explanatory figures, color photographs, graphics and tables. It will be easy to read and give the reader a complete understanding and state of the art of the exciting science and its applications.
The Transplant Imaginary
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Author : Lesley A. Sharp
language : en
Publisher: Univ of California Press
Release Date : 2014
The Transplant Imaginary written by Lesley A. Sharp and has been published by Univ of California Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Medical categories.
In The Transplant Imaginary, author Lesley Sharp explores the extraordinarily surgically successful realm of organ transplantation, which is plagued worldwide by the scarcity of donated human parts, a quandary that generates ongoing debates over the marketing of organs as patients die waiting for replacements. These widespread anxieties within and beyond medicine over organ scarcity inspire seemingly futuristic trajectories in other fields. Especially prominent, longstanding, and promising domains include xenotransplantation, or efforts to cull fleshy organs from animals for human use, and bioengineering, a field peopled with “tinkerers” intent on designing implantable mechanical devices, where the heart is of special interest. Scarcity, suffering, and sacrifice are pervasive and, seemingly, inescapable themes that frame the transplant imaginary. Xenotransplant experts and bioengineers at work in labs in five Anglophone countries share a marked determination to eliminate scarcity and human suffering, certain that their efforts might one day altogether eliminate any need for parts of human origin. A premise that drives Sharp’s compelling ethnographic project is that high-stakes experimentation inspires moral thinking, informing scientists’ determination to redirect the surgical trajectory of transplantation and, ultimately, alter the integrity of the human form.