Extracellular Vesicles
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Extracellular Vesicles In Health And Disease
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Author : Paul Harrison
language : en
Publisher: CRC Press
Release Date : 2014-05-02
Extracellular Vesicles In Health And Disease written by Paul Harrison and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-02 with Medical categories.
Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated in a number of diseases. This raises the question of their direct role
Extracellular Vesicles And Their Importance In Human Health
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Author : Ana Gil De Bona
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-03-04
Extracellular Vesicles And Their Importance In Human Health written by Ana Gil De Bona and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-04 with Science categories.
Extracellular vesicle is a wide term that involves many different types of vesicles. Almost all the cell types studied secrete vesicles to the extracellular environment related to cell - cell communication. Extracellular vesicles have been found in different biological fluids, such as blood, milk, saliva, tears, urine, and cerebrospinal fluid. These vesicles transport different molecules, including mRNA, proteins, and lipids, some of them cell type specific that make them ideal biomarkers in both health and disease conditions. However, their contribution to different conditions is not well understood. The aim of this book is to provide an overview of the extracellular vesicles in the human body, how they are internalized, and their participation in several diseases.
Biomedical Applications Of Extracellular Vesicles
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Author : Zhenhua Li
language : en
Publisher: John Wiley & Sons
Release Date : 2023-11-29
Biomedical Applications Of Extracellular Vesicles written by Zhenhua Li and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-29 with Science categories.
Biomedical Applications of Extracellular Vesicles Unique resource focusing on biomedical applications and clinical translation of extracellular vesicles in science and medicine Focusing on key points to better understand extracellular vesicles (EVs) and their development, Biomedical Applications of Extracellular Vesicles describes in detail the biogenesis of EVs, the mechanism of intercellular communication, and the treatment of various diseases of EVs and the EV-based drug delivery platforms. An application-oriented resource, the work presents rapidly newer biomedical and clinical applications of natural and engineered EVs such as drug delivery, diagnosis, prognosis monitoring, immunotherapy, and more. The first part of this book provides a basic background on EVs. Next, the book introduces the excellent therapeutic effects of EVs themselves and the underlying mechanisms, followed by how EVs from different sources were used to construct drug delivery platforms. The latest research on EVs from leading groups around the world is presented. Sample topics covered in Biomedical Applications of Extracellular Vesicles include: Biogenesis of various EVs Pros and cons of the different instrumental and methodological developments for analytical strategies applied to EVs EVs in treatment of major diseases, such as cancer, cardiovascular and respiratory diseases Current methods of engineering EVs, and a comparison of the advantages and disadvantages of each method Biomaterials, such as hydrogels, scaffolds, and microneedles, that have been developed to further enhance the therapeutic efficacy of EVs Key challenges, such as quality control, scalability, and biosafety, that limit the clinical and industrial translation of EVs Explaining in detail how extracellular vesicles are produced and engineered, along with potential applications and commercial developments of EVs in science and industry, Biomedical Applications of Extracellular Vesicles is an essential resource on the subject for chemists, cell biologists, and molecular physicists.
Extracellular Vesicles
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Author : Qian Wang
language : en
Publisher: Springer Nature
Release Date :
Extracellular Vesicles written by Qian Wang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Extracellular Vesicles
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-10-24
Extracellular Vesicles written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-24 with Science categories.
Extracellular Vesicles, Volume 645 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Genetic labeling of extracellular vesicle exosomes for studying biogenesis and uptake in living mammalian cells, Fluorescent Labeling of Extracellular Vesicles, Isolation of extracellular vesicles from lymph, Transgenic rats for tracking body fluid/tissue-derived extracellular vesicles, Isolation of amniotic extracellular vesicles, Urinary extracellular vesicle isolation, Immunocapture-based ELISA to Characterize and Quantify Extracellular Vesicles in Both Cell Culture Supernatants and Body Fluids, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series
Extracellular Vesicles
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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2022-07-20
Extracellular Vesicles written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-20 with Science categories.
Extracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling. This book provides critical information on the fundamentals of EVs, their roles in diseases like cancer, and their use in disease management. The chapters emphasize the emerging data confirming the role of EVs in the pathogenesis of diseases and discuss the scientific advances that have made it feasible to characterize and engineer EVs, leading to their use as tools in biomarker discovery and disease diagnosis, prognosis, therapeutic application, and theranostics. This volume is a valuable resource for basic biologists, translational scientists, and clinicians.
Extracellular Vesicles For Therapeutic And Diagnostic Applications
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Author : Anand Krishnan
language : en
Publisher: Elsevier
Release Date : 2025-01-02
Extracellular Vesicles For Therapeutic And Diagnostic Applications written by Anand Krishnan and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-02 with Technology & Engineering categories.
Extracellular Vesicles for Therapeutic and Diagnostic Applications provides an introduction to exosomes and extracellular vesicles, including their unique properties and characterization, before detailing the most-utilized isolation, purification, and surface engineering techniques for their preparation as therapeutic and diagnostic agents. This book reviews recent developments in interdisciplinary research on exosome structure, properties, and engineering approaches as well as their use in diagnosis and treatment of a variety of illnesses such as cancer, tuberculosis, Alzheimer's disease, ophthalmic diseases, and others. Extracellular Vesicles for Therapeutic and Diagnostic Applications is an important reference for those interested in the development and application of exosomes and extracellular vesicles as biomaterials for us in the diagnosis and treatment of disease.
Extracellular Vesicles
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Author : Wojciech Chrzanowski
language : en
Publisher: Royal Society of Chemistry
Release Date : 2021-10-20
Extracellular Vesicles written by Wojciech Chrzanowski and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-20 with Technology & Engineering categories.
Extracellular and biofluids vesicles (EVs) are highly specialised yet ubiquitous nanoscale messengers secreted by cells. With the development of stem cell engineering, EVs promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field. Covering basic cell biology, including EV production and intracellular communication, this book will provide material scientists and engineers with a foundation to the necessary biology. The reader will then learn about the isolation of extracellular vesicles their physicochemical characterisation and therapeutic application of EVs in regenerative medicine as well as their potential as biomarkers in medical diagnostic. This book will also discuss the regulatory landscape of EVs. Bridging cell biology, biomaterials, biophysics and biomedical engineering the content of this book is written with a broad interdisciplinary audience in mind. Researchers, new and established will find this a must-have on their shelf.
Novel Clinical Applications Of Extracellular Vesicles
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Author : Matías Sáenz-Cuesta
language : en
Publisher: Frontiers Media SA
Release Date : 2015-08-14
Novel Clinical Applications Of Extracellular Vesicles written by Matías Sáenz-Cuesta and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-14 with Medicine (General) categories.
During the last years, the research on extracellular vesicles (EVs) has raised giving new insights into pathophysiology of several diseases. EVs are membrane-bound particles secreted by almost all cell types. Depending on their biogenesis and size they include exosomes, microparticles / microvesicles and apoptotic bodies. Characteristically, EVs carry markers from the source cell membrane and contain genetic material, lipids and proteins inside. They are known to play a role in cell-to-cell communication and to produce genotypic and phenotypic modifications in the target cell including: antigen presentation, apoptosis induction, cellular activation, inhibition or differentiation. In particular, increasing concentrations of EVs have been found in many diseases such as cancer, autoimmune and cardiovascular diseases, among others. Most of the studies in EVs are focused on the characterization of EVs compounds, identifying mechanism of action, their potential use as biomarkers, and few of them investigate a therapeutic usage. However, there are some issues to be achieved on the path to their clinical application. This research topic offers a common place to discuss current and novel clinical applications of EVs pointing on future directions. We encouraged the submission of original articles, reviews, hypothesis, controversies, future perspectives and personal viewpoints on the following topics of interest, but not limited to: • Contribution of EVs to better understand the pathology of immunological diseases. • Standardization of isolation and quantification protocols in the daily clinical practice. • Possible applications of EVs as clinical biomarkers (diagnostic, prognostic and evolution marker). • Therapeutic role of EVs being vehicles of specific cargo: current clinical trials? • Novel immunological functions of EVs.
Extracellular Vesicles In Infectious Diseases
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Author : Shulamit Michaeli
language : en
Publisher: Frontiers Media SA
Release Date : 2021-07-22
Extracellular Vesicles In Infectious Diseases written by Shulamit Michaeli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-22 with Science categories.