Force Of The Heart


Force Of The Heart
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Mechanisms Of Contraction Of The Normal And Failing Heart


Mechanisms Of Contraction Of The Normal And Failing Heart
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Author : Eugene Braunwald
language : en
Publisher:
Release Date : 1968

Mechanisms Of Contraction Of The Normal And Failing Heart written by Eugene Braunwald and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with Heart categories.




Factors Influencing Measurement Of Contractile Force Of Heart Muscle In Situ


Factors Influencing Measurement Of Contractile Force Of Heart Muscle In Situ
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Author : Robert Petrie Walton
language : en
Publisher:
Release Date : 1950

Factors Influencing Measurement Of Contractile Force Of Heart Muscle In Situ written by Robert Petrie Walton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1950 with categories.




The Interval Force Relationship Of The Heart


The Interval Force Relationship Of The Heart
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Author : Mark I. M. Noble
language : en
Publisher: Cambridge University Press
Release Date : 1992-08-27

The Interval Force Relationship Of The Heart written by Mark I. M. Noble and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-08-27 with Medical categories.


This 1992 volume examines the important relationship, initially studied in 1871 by Bowditch, between the strength of the heartbeat and the interval between beats.



Excitation Contraction Coupling And Cardiac Contractile Force


Excitation Contraction Coupling And Cardiac Contractile Force
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Author : Donald Bers
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Excitation Contraction Coupling And Cardiac Contractile Force written by Donald Bers and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


How is the heartbeat generated? What controls the strength of contraction of heart muscle? What are the links between cardiac structure and function? How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart? Are there important species differences in how contraction is regulated in the heart? How do the new molecular data fit together in understanding the heart beat? What goes wrong in ischemia, hypertrophy, and heart failure? This book paints a modern `portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction. The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure). Excitation-Contraction Coupling and Cardiac Contractile Force – Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields.



Regulation Of Coronary Blood Flow


Regulation Of Coronary Blood Flow
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Author : Michitoshi Inoue
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-09

Regulation Of Coronary Blood Flow written by Michitoshi Inoue and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-09 with Medical categories.


Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.



Regulation Of Cardiac Contractility


Regulation Of Cardiac Contractility
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Author : R. John Solaro
language : en
Publisher: Biota Publishing
Release Date : 2011-04-01

Regulation Of Cardiac Contractility written by R. John Solaro and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-01 with Medical categories.


Contractility describes the relative ability of the heart to eject a stroke volume (SV) at a given prevailing afterload (arterial pressure) and preload (end-diastolic volume; EDV). Various measures of contractility are related to the fraction as the SV/EDV or the ejection fraction, and the dynamics of ejection as determined from maximum pressure rise in the ventricles or arteries or from aortic flow velocities determined by echocardiography. At the cellular level, the ultimate determinant of contractility is the relative tension generation and shortening capability of the molecular motors (myosin cross-bridges) of the sarcomeres as determined by the rates and extent of Ca activation, the turnover kinetics of the cross-bridges, and the relative Ca responsiveness of the sarcomeres. Engagement of the regulatory signaling cascades controlling contractility occurs with occupancy and signal transduction by receptors for neurohumors of the autonomic nervous system as well as growth and stress signaling pathways. Contractility is also determined by the prevailing conditions of pH, temperature, and redox state. Short-term control of contractility is fully expressed during exercise. In long-term responses to stresses on the heart, contractility is modified by cellular remodeling and altered signaling that may compensate for a time but which ultimately may fail, leading to disorders.



Comparative Physiology Of The Heart


Comparative Physiology Of The Heart
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Author : A. J. Clark
language : en
Publisher: Cambridge University Press
Release Date : 2015-04-09

Comparative Physiology Of The Heart written by A. J. Clark and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-09 with Science categories.


Originally published in 1927, this book examines the composition and function of the heart in a range of animals. Clark examines how the function of the heart differs between members of the same species who are not of the same size and the differences in heart structure between cold- and warm-blooded animals.



Disquisitions Concerning The Force Of The Heart The Dimensions Of The Coats Of The Arteries And The Circulation Of The Blood


Disquisitions Concerning The Force Of The Heart The Dimensions Of The Coats Of The Arteries And The Circulation Of The Blood
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Author : Joseph Morland
language : en
Publisher:
Release Date : 1713

Disquisitions Concerning The Force Of The Heart The Dimensions Of The Coats Of The Arteries And The Circulation Of The Blood written by Joseph Morland and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1713 with Arteries categories.




Ventricular Function


Ventricular Function
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Author : David C. Warltier
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1995

Ventricular Function written by David C. Warltier and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Medical categories.




The Inertial Isolation Of The Human Heart As A Force Generator


The Inertial Isolation Of The Human Heart As A Force Generator
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Author : Paul Arthur Crafton
language : en
Publisher:
Release Date : 1956

The Inertial Isolation Of The Human Heart As A Force Generator written by Paul Arthur Crafton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1956 with Heart categories.