Frail Heart

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Frail Heart

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Author : Connie Fillippelli
language : en
Publisher:
Release Date : 1999

Frail Heart written by Connie Fillippelli and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.

Frailty And Cardiovascular Diseases

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Author : Nicola Veronese
language : en
Publisher: Springer Nature
Release Date : 2020-01-01

Frailty And Cardiovascular Diseases written by Nicola Veronese and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-01 with Medical categories.

This book aims to clarify the potential association between frailty and cardiovascular disease in older people. Covering the biological as well as the clinical point of view, it allows researchers and clinicians to discover the significance of this topic. The contributions cover the most important aspects in the potential relationship between frailty and cardiovascular disease. In particular, authoritative authors in this field have clarified the definition and the epidemiology of frailty and cardiovascular disease in older people. A large part of the volume is dedicated to the biological mechanisms of frailty and cardiovascular disease, trying to find those in common between these two conditions. Since this book is dedicated to both researchers and clinicians, we have proposed some chapters to the importance of comprehensive geriatric assessment in the evaluation and treatment of cardiovascular diseases and frailty. In this regard, the importance of geriatric evaluation in cardiac surgery for older people is well covered. Finally, the importance of cardiac rehabilitation and physical exercise is summarized, being, actually, the most important treatments for both frailty and cardiovascular disease. Written by many well-known and widely published experts in their respective fields, this book will appeal to a wide readership such as researchers in the field and clinicians, especially suited in geriatric medicine and cardiology who, every day, face frail older patients.

Cardiac Management In The Frail Elderly Patient And The Oldest Old

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Author : Andrea Ungar
language : en
Publisher: Springer
Release Date : 2017-03-14

Cardiac Management In The Frail Elderly Patient And The Oldest Old written by Andrea Ungar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-14 with Medical categories.

This book focuses specifically on the management of cardiovascular disease in elderly patients with particular frailties and in the “oldest old”. It is clearly explained how treatment in these patients differs from that in patients in their seventies who respond well to therapies and do not present frailties or organ failures. Although not young, the latter patients can be treated almost like any other patient, according to established guidelines. In contrast, the frail, compromised elderly and the oldest old require specific measures that target their needs, including with respect to underlying renal conditions. The book considers all those pathologies that have a high prevalence in the general population, explaining advanced treatment concepts and all aspects of assessment. Key clinical points are highlighted, and the text is supplemented with numerous informative figures and tables. The authors are respected experts, for the most part geriatric physicians, and the book is especially addressed to cardiologists, who may lack the described targeted information and treatment tools.

The Impact Of Age And Frailty On The Fischer 344 Rat Heart

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Author : Amy Yorke
language : en
Publisher:
Release Date : 2017

The Impact Of Age And Frailty On The Fischer 344 Rat Heart written by Amy Yorke and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.

The purpose of this study was to develop a frailty index (FI) for rats, and characterize the impact of age and frailty on cardiac parameters at baseline and following cardioplegic arrest. Data on survival and 45 variables in health systems known to change with age were serially collected in a longitudinal study of male F344 rats to develop a 30-item FI. Frailty increased with age and was associated with an increase in mortality. Cardiac function was assessed in vivo, and in the isolated working heart. We also developed a novel method to assess diastolic function in the isolated working heart. Aged and frail hearts were more arrhythmic at baseline, however neither age nor frailty were associated with statistically significant changes in cardiac structure or function in vivo or in the isolated working heart. Functional recovery after arrest with del Nido cardioplegia was similar when compared by age and frailty.

Lifelines

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Author : Muriel R. Gillick
language : en
Publisher: W. W. Norton
Release Date : 2001

Lifelines written by Muriel R. Gillick and has been published by W. W. Norton this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Family & Relationships categories.

Discusses the medical, ethical, and social implications of an increased life expectancy, including the growing numbers of frail elderly, and offers advice on coping with the chronic ailments and emotional problems of aging.

Assessment Of Frailty And Quality Of Life In Octogenarians With Symptomatic Coronary Artery Disease

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Author : Shouaib Qayyumm
language : en
Publisher:
Release Date : 2020

Assessment Of Frailty And Quality Of Life In Octogenarians With Symptomatic Coronary Artery Disease written by Shouaib Qayyumm and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.

The Impact Of Age And Frailty On Cardiac Function In Health And Disease Conditions In Naturally Ageing Mice

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Author : Hirad Feridooni
language : en
Publisher:
Release Date : 2019

The Impact Of Age And Frailty On Cardiac Function In Health And Disease Conditions In Naturally Ageing Mice written by Hirad Feridooni and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.

Frail people with cardiovascular disease experience worse outcomes and higher mortality than non-frail patients, but the links between frailty and myocardial function are unclear. Frailty was quantified as deficit accumulation in adult (≈8 mos) and aged (≈27 mos) C57BL/6 male mice using the mouse clinical Frailty Index (FI). Under basal conditions, left ventricular developed pressure plus +dP/dt and -dP/dt declined with age. Myocytes from aged mice had smaller contractions, Ca2+ transients and Ca2+ currents. Interestingly this age-dependent remodelling in the intact hearts and individual myocytes was graded by frailty. Aged hearts had better functional recovery than adult hearts following IR. Functional recovery was not correlated with frailty. These results show that age-dependent cardiac remodelling at the level of the intact heart and at the cellular and subcellular levels are graded by the overall health of the mouse and that there may be underlying mechanisms that protect against IR in ageing.

Cross Sectional Analysis Of Frailty Status And Heart Rate Variability At Rest And During Exercise In Older Adult Females

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Author : Nicole Johnston
language : en
Publisher:
Release Date : 2020

Cross Sectional Analysis Of Frailty Status And Heart Rate Variability At Rest And During Exercise In Older Adult Females written by Nicole Johnston and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.

Frailty is related to an imbalance of homeostasis within the body, accompanied by an accumulation of health deficits. A possible way to measure this imbalance, is with a non-invasive measure of the autonomic nervous system through heart rate variability (HRV). This study utilized a secondary, cross-sectional analysis of data collected in the Women's Advanced Risk-Assessment in Manitoba (WARM) Hearts study. The purpose was to determine if there is a difference in HRV depending on frailty level measured by the WARM Hearts HRV Frailty Index (WH-HRV FI) and the Standardized Frailty Phenotype measured at rest and during moderate exercise; and to determine if there is an association between HRV and frailty when measuring frailty on a continuous scale both at rest and during moderate exercise. Data analysis included 125 females in the resting cohort, and 102 in the exercise cohort. Frailty was measured using two separate methods (WH-HRV FI and the Standardized Frailty Phenotype). HRV was measured using a Polar H7 heart rate monitor with a 5-minute sample at rest and a 2-minute sample during exercise. This analysis included various HRV indices including mean RR intervals (Mean RR), standard deviation of normal-normal intervals (SDNN), root mean square of successive intervals (RMSSD), low frequency (LF), high frequency (HF), total power (TP), low frequency to high frequency ratio (LF/HF), and approximate entropy (ApEn). Resting analysis revealed a trend towards a reduction in SDNNlog, TPlog, and LF/HFlog and a significant positive association in LFlog in those who were frail with no changes of RMSSDlog or HFlog indicating an impaired sympathetic nervous system (SNS). Exercise analysis revealed a significant difference and positive association between frailty and mean RRlog, and an inverse relationship between frailty and TPlog. This indicates a reduced ability to adapt to changes and a reduced global HRV for both frailty measures. There were inconsistent results regarding the direction of the association between LFlog and SDNNlog between frailty tools. Overall, there may be an impairment in SNS activity at rest and a reduced ability to adapt, along with decreased global HRV (TPlog) during exercise in those who have increased levels of frailty.

Frail Human Heart The Name Of The Blade Book Three

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Author : Zoe Marriott
language : en
Publisher: National Geographic Books
Release Date : 2016-11-08

Frail Human Heart The Name Of The Blade Book Three written by Zoe Marriott and has been published by National Geographic Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-08 with Juvenile Fiction categories.

In the riveting final volume of Zoë Marriott’s urban fantasy trilogy, all hell is breaking loose in London. Literally. It’s been a long few days since Mio stole the ancient, magical katana from her family’s attic. She and her friends have defeated the demonic Nekomata and banished the Goddess of Death’s plague-spreading Shikome. But at a terrible cost: Mio’s beloved Shinobu is lost to her, imprisoned again within the katana. With no time to succumb to guilt and grief, Mio must find a way to defeat the vengeful gods Izanagi and Izanami once and for all. Her only hope lies in the one place immortals can’t go: the realm of dreams, a shifting dimension of water and ice, echoes and memories, beauty and danger.

The Fragile Heart

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Author : Jean Evans
language : en
Publisher:
Release Date : 1994-01-01

The Fragile Heart written by Jean Evans and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-01-01 with categories.