Free Breathing Non Ecg T1 Mapping In The Heart
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Free Breathing Non Ecg T1 Mapping In The Heart
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Author : Jaime Shaw
language : en
Publisher:
Release Date : 2017
Free Breathing Non Ecg T1 Mapping In The Heart written by Jaime Shaw and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Cardiovascular diseases are the leading cause of death in the United States, translating to a high cost burden on the healthcare system. Noninvasive imaging can play a significant role in the diagnosis and triaging of cardiovascular diseases. Cardiac MRI is a noninvasive imaging technique becoming more prevalent due to its advantage of providing excellent soft-tissue contrast and high spatial resolution without the use of ionizing radiation; however, major challenges exist including respiratory and cardiac motion. One emerging application of cardiac MRI is myocardial tissue characterization using quantitative mapping techniques. Current mapping techniques rely on electrocardiogram (ECG)-gating which assumes normal sinus rhythm, as well as breath-holds or respiratory monitoring which preclude some patients from scans or prolong scan time. Quantification of spin-lattice relaxation times (or T1 mapping) of the myocardium has been shown to enable detection of diffuse myocardial fibrosis, a key feature in the progression of many cardiac diseases. The main focus of this dissertation is to remove the limitations of ECGs and respiratory monitoring from cardiac MRI to enable free-breathing, non-ECG T1 mapping. The first objective of this dissertation was to develop a two-dimensional, free-breathing, non-ECG, continuous T1 mapping technique and validate it in imaging phantoms using a gold-standard technique. We compare the T1 and extracellular volume (ECV) values to a conventional breath-hold, ECG-gated, T1 mapping technique in healthy subjects. The repeatability and accuracy of the technique were assessed for different length scans. The second objective was to demonstrate the feasibility of quantifying T1 values throughout the cardiac cycle and to assess cardiac function simultaneously with a method free of ECG and prospective respiratory monitoring. The third objective of this dissertation was to develop a three-dimensional free-breathing, non-ECG T1 mapping technique capable of providing T1 and ECV maps with full coverage of the left ventricle. This dissertation lays the groundwork for quantitative cardiac MRI with no reliance on prospective respiratory monitoring or ECGs. The removal of these limitations makes cardiac MRI accessible to all types of patients and provides a comfortable scan environment with no breath-holding. This dissertation represents a move toward a "push-button" cardiac MRI paradigm, wherein one scan with minimal setup can provide information comparable to a complex standard-of-care cardiac MRI scan.
Diseases Of The Chest Breast Heart And Vessels 2019 2022
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Author : Juerg Hodler
language : en
Publisher: Springer
Release Date : 2019-02-19
Diseases Of The Chest Breast Heart And Vessels 2019 2022 written by Juerg Hodler and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-19 with Medical categories.
This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology.
Fdg Pet Ct And Pet Mr In Cardiovascular Diseases
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Author : Matthieu Pelletier-Galarneau
language : en
Publisher: Springer Nature
Release Date : 2022-10-13
Fdg Pet Ct And Pet Mr In Cardiovascular Diseases written by Matthieu Pelletier-Galarneau and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-13 with Medical categories.
This book is a clinically oriented, up-to-date, and in-depth review of the various applications of FDG-PET/CT and PET/MR in cardiovascular diseases with emphasis on the current available evidence. Positron emission tomography (PET) imaging with fluorodeoxyglucose (FDG) has seen increased applications in cardiovascular diseases over the last decades. Its utility is already established in a wide range of conditions, including myocardial viability imaging, assessment of inflammatory diseases such as sarcoidosis and vasculitis, as well as imaging of infectious processes, such as infective endocarditis and cardiac implantable electronic device infection. In addition, there are several emerging indications such as the imaging of left ventricular assisting device infection and native valve endocarditis as well as new applications under investigation. The first section of the book reviews the technical basis of cardiovascular PET/CT and PET/MR imaging as well as cardiac metabolism. The following chapters each present specific pathologies, presenting epidemiology, pathophysiology, and diagnostic strategies, along with high quality clinical cases to support the discussion. The final chapter is a review of 15 interesting and clinically relevant cases. This is an ideal guide for nuclear medicine physicians, cardiologists, radiologists, residents, post-graduate fellows, and technologists.
Cardiovascular Magnetic Resonance Imaging
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Author : Raymond Y. Kwong
language : en
Publisher: Springer
Release Date : 2019-01-31
Cardiovascular Magnetic Resonance Imaging written by Raymond Y. Kwong and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-31 with Medical categories.
The significantly updated second edition of this important work provides an up-to-date and comprehensive overview of cardiovascular magnetic resonance imaging (CMR), a rapidly evolving tool for diagnosis and intervention of cardiovascular disease. New and updated chapters focus on recent applications of CMR such as electrophysiological ablative treatment of arrhythmias, targeted molecular MRI, and T1 mapping methods. The book presents a state-of-the-art compilation of expert contributions to the field, each examining normal and pathologic anatomy of the cardiovascular system as assessed by magnetic resonance imaging. Functional techniques such as myocardial perfusion imaging and assessment of flow velocity are emphasized, along with the exciting areas of artherosclerosis plaque imaging and targeted MRI. This cutting-edge volume represents a multi-disciplinary approach to the field, with contributions from experts in cardiology, radiology, physics, engineering, physiology and biochemistry, and offers new directions in noninvasive imaging. The Second Edition of Cardiovascular Magnetic Resonance Imaging is an essential resource for cardiologists and radiologists striving to lead the way into the future of this important field.
Coronary Magnetic Resonance Angiography
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Author : Andre J. Duerinckx
language : en
Publisher: Springer Science & Business Media
Release Date : 2002
Coronary Magnetic Resonance Angiography written by Andre J. Duerinckx and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
In recent years, there has been increasing interest in the clinical applications of coronary angiography techniques. Coronary MRA can be instrumental in the evaluation of congenital coronary artery anomalies, however, the complexity of advanced MR pulse sequences and strategies may be overwhelming to many. Coronary MR Angiography demystifies the art of coronary MRA by providing a text in plain language with clearly illustrated imaging steps and protocols. Designed to bridge the gap between radiology and cardiology, it is written for physicians and scientists planning to incorporate this technique into their research or practice.
Quantitative Imaging Qi And Artificial Intelligence Ai In Cardiovascular Diseases
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Author : Sebastian Kelle
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-17
Quantitative Imaging Qi And Artificial Intelligence Ai In Cardiovascular Diseases written by Sebastian Kelle and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-17 with Medical categories.
Quantitative Magnetic Resonance Imaging
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Author : Nicole Seiberlich
language : en
Publisher: Academic Press
Release Date : 2020-11-18
Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-18 with Computers categories.
Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Development Of Mri Techniques For Tissue Characterization Using Magnetic Resonance Multitasking
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Author : Pei Han
language : en
Publisher:
Release Date : 2022
Development Of Mri Techniques For Tissue Characterization Using Magnetic Resonance Multitasking written by Pei Han and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.
Magnetic resonance multitasking (MR Multitasking) is a multi-dimensional imaging framework that was developed recently. With low-rank tensor modeling, signal correlation among images at different time dimensions are exploited in MR Multitasking to resolve motion, accelerate image acquisition, and enhance image quality. Though initially developed for cardiovascular imaging, it has also been extended to many other applications, such as whole-brain multi-parametric mapping, free-breathing abdominal dynamic contrast enhanced imaging, etc. The primary focus of this dissertation is to improve two important MR tissue characterization techniques using MR Multitasking: (1) Electrocardiogram (ECG)-less myocardial T1 and extracellular volume fraction (ECV) mapping in small animals at 9.4 T, and (2) Fast 3D chemical exchange saturation transfer (CEST) imaging for human studies at 3.0 T. ECV quantification with cardiovascular magnetic resonance T1 mapping is a powerful tool for the characterization of focal or diffuse myocardial fibrosis. However, it is technically challenging to acquire high-quality T1 and ECV maps in small animals for preclinical research because of high heart rates and high respiration rates. An ECG-less, free-breathing ECV mapping method using MR Multitasking was developed on a 9.4 T small animal MR system. The feasibility of characterizing diffuse myocardial fibrosis was tested in a rat heart failure model with preserved ejection fraction (HFpEF). A 25-min exam, including two 4-min T1 Multitasking scans before and after gadolinium injection, were performed on each rat. It allows a cardiac temporal resolution of 20 ms for a heart rate of ~300 bpm. Elevated ECV found in the HFpEF group is consistent with previous human studies and well correlated with histological data. This technique has the potential to be a viable imaging tool for myocardial tissue characterization in small animal models. CEST imaging is a non-contrast MRI technique that indirectly detects exchangeable protons in the water pool. It is achieved by performing frequency selective saturation at those protons before acquiring water signal readout. CEST MRI provides a novel contrast mechanism to image important physiological information, such as pH and metabolite concentration. However, long scan time is still a crucial problem in many CEST imaging applications, which makes it difficult to translate current CEST techniques into clinical practice. A novel 3D steady-state CEST method using MR Multitasking was developed in the brain at 3.0 T. This allows the Z-spectrum of 55 frequency offsets to be acquired with whole-brain coverage at 1.7 x 1.7 x 3.0 mm3 spatial resolution in 5.5 min. Quantitative CEST maps from multi-pool fitting showed consistent image quality across the volume. Motion handling in moving organs is another challenge for practical CEST imaging. For instance, breath-holding is currently needed in liver CEST imaging to reduce motion artifacts, which limits not only spatial resolution, but also scan volume coverage. Following the whole-brain CEST protocol, a respiration-resolved 3D abdominal CEST imaging technique using MR Multitasking was developed, which enables whole-liver coverage with free-breathing acquisition. CEST images of 55 frequency offsets with entire-liver coverage and 2.0 x 2.0 x 6.0 mm3 spatial resolution were generated within 9 min. Both APTw and glycoCEST signals showed high sensitivity between post-fasting and post-meal acquisitions.
Simultaneous Multiparametric And Multidimensional Cardiovascular Magnetic Resonance Imaging
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Author : Aleksandra Radjenovic
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-30
Simultaneous Multiparametric And Multidimensional Cardiovascular Magnetic Resonance Imaging written by Aleksandra Radjenovic and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-30 with Medical categories.
The Eacvi Textbook Of Cardiovascular Magnetic Resonance
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Author : Victor Ferrari
language : en
Publisher: Oxford University Press
Release Date : 2018-09-13
The Eacvi Textbook Of Cardiovascular Magnetic Resonance written by Victor Ferrari and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-13 with Medical categories.
This highly comprehensive and informed textbook has been prepared by the Cardiovascular Magnetic Resonance section of the European Society of Cardiology association on imaging, the EACVI. The EACVI Textbook of Cardiovascular Magnetic Resonance is the authority on the subject. The textbook is aligned with ESC Core Curriculum and EACVI Core Syllabus for CMR. It is a practical resource and provides a disease orientated outlook on the subject. Structured with thirteen clear and detailed sections, ranging from Physics to Methodology, and featuring specific sections on ischemic heart disease, myocardial disease, pericardial disease, and congenital heart disease and adult congenital heart disease, The EACVI Textbook of Cardiovascular Magnetic Resonance provides extensive knowledge across the entire subject area in CMR. Beautifully illustrated and physical principles enriched with schematic animations, the textbook is advanced further with key video content based on clinical cases. Written by leading experts in the field from across the world, the textbook aims to summarise the existing research and clinical evidence for the various CMR indications and provide an invaluable resource for cardiologists and radiologists across the board. The textbook is ideal for cardiologists and radiologists new to the field of Cardiovascular Magnetic Resonance, those preparing for ESC certification in CMR, and those established in the field wishing to gain a deep understanding of CMR. Online access to the digital version is included with purchase of the print book, with accompanying videos referenced within the text available on Oxford Medicine Online.