Free Radicals In Brain Pathophysiology
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Free Radicals In Brain Pathophysiology
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Author : Giuseppe Poli
language : en
Publisher: CRC Press
Release Date : 2000-02-25
Free Radicals In Brain Pathophysiology written by Giuseppe Poli and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-02-25 with Medical categories.
This volume provides an authoritative, comprehensive view of the most current issues in brain pathophysiology and offers a critical evaluation of antioxidant-based therapeutic approaches to neurodegeneration, providing an up-to-date account of the role of antioxidants in the prevention and moderation of clinical symptoms. Examines free radicals
Oxidative Stress And Free Radical Damage In Neurology
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Author : Natan Gadoth
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-19
Oxidative Stress And Free Radical Damage In Neurology written by Natan Gadoth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-19 with Medical categories.
The role of free radicals and oxidative stress in neurological disorders has only recently been recognized, leaving clinical neurologists to seek in vain for information on the subject even in major textbooks. What published information there is may consist of brief reminders of the possible association of superoxidase dismutase with familial amyotrophic lateral sclerosis and nitrous oxide with migraine. With luck they may also find information on the purported role of free radicals in the pathogenesis of traumatic brain injury. Oxidative Stress and Free Radical Damage in Neurology sets the record straight, focusing on clinical and research issues regarding the interplay of free radicals and the human nervous system. Crucially, the chapters cover numerous antioxidants and their possible therapeutic role in neurological disorders. Key illnesses such as epilepsy, multiple sclerosis and Parkinson’s are analyzed, and chapters also examine more general issues such as the link between free radicals and inflammation of the central nervous system. Clinicians and laboratory researchers alike will find that this book augments their understanding not only of the widespread involvement of free radicals in the central nervous system but also of some uncertainties surrounding whether free radical damage in neurology plays a primary or secondary role.
Free Radicals In The Brain
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Author : Lester Packer
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Free Radicals In The Brain written by Lester Packer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Free radicals appear to play a mojor role in many neurological (and non neurological) dieseases. Both acute and degenerative disorders are thought to involve free radicals reactions in tissue injury (for a list see this book page 18). This issue is very important for basic science and for therapeuthic approach as well. In order to review and discuss the place of free radicals in psychiatry and neurology, a joint meeting was initiated by the World Health Organization and the Fondation Ipsen in Paris on June 17-18,1991. This book contains the papers presented during this meeting. Although the papers included in this volume have been produced in the framework of WHO/Fondation Ipsen review of knowledge about free radicals and brain disorders, they express the views of the individual authors rather than a consensus of the participants at the meeting. They do not necessarily represent the decision or stated policy of the World Health Organiszation or the Fondation Ipsen. The editors wish to express their appreciation to Mrs Mervaillie for the organization of the meeting and Mrs M.-L. Gage for her editorial assis tance. L. Packer, L. Prilipko, Y Christen Contents Free Radical Scavengers and Antioxidants in Prophylaxy and Treatment of Brain Diseases L. Packer ........................................... 1 Reactive Oxygen Species and the Central Nervous System B. Halliwell .... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 . . . . . . . . .
Free Radicals Oxidative Stress And Antioxidants
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Author : Tomris Özben
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Free Radicals Oxidative Stress And Antioxidants written by Tomris Özben and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
There has been an explosion of research related to free radicals and antioxidants in recent years, and hundreds of laboratories worldwide are actively involved in many as pects of free radicals, oxidative stress, and antioxidants. The literature on these topics in creases exponentially every year. Over the last few years, we have been fortunate to witness a widespread recognition of the important role of free radicals in a wide variety of pathological conditions including diseases such as atherosclerosis, cardiovascular and neurological diseases, ischemia, emphysema, diabetes, radiation injury, cancer, etc. In ad dition, many laboratories are studying the role of free radicals in the inexorable process of aging. Increased evidence involves free radicals with the etiology of various diseases, thereby suggesting the use of antioxidants as a viable therapeutic approach for the treat ment of free radical mediated pathologies. Despite these impressive developments, many important aspects of free radical and antioxidant research are open for investigation. It is important to understand the overall mechanisms involved in free radical mediated physiological and pathological conditions. This knowledge will undoubtedly lead to the development of new therapeutic approaches to prevent or control free radical related diseases. This book contains the proceedings of the NATO Advanced Study Institute (ASI) on "Free Radicals, Oxidative Stress, and Antioxidants: Pathological and Physiological Sig nificance," which was held in Antalya, Turkey from May 24-June 4, 1997.
Free Radicals In Human Health And Disease
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Author : Vibha Rani
language : en
Publisher: Springer
Release Date : 2014-11-14
Free Radicals In Human Health And Disease written by Vibha Rani and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-14 with Science categories.
The role of oxidative stress in human disease has become an area of intense interest. Free radicals, a normal product of metabolism, exist in all aerobic cells in balance with biochemical antioxidants. Environmental stress increases the levels of free radicals drastically, thereby disturbing the equilibrium between free radical production and the antioxidant capability causing oxidative stress. Over the years, ROS has been implicated in the pathologies of various diseases like cancer, neurological disorder, cardiovascular diseases rheumatoid arthritis, diabetes etc. This book provides an in depth critical state-of-art reviews from established investigators on free radicals, ROS associated pathogenesis of human diseases, biomarkers of oxidative damage, antioxidants, phytonutrients and other related health concerns of modern society. The present book is aimed at graduate students, researchers in academia, industry and clinicians with the interest in redox biology. Special attention has been devoted to the topic of ROS signalling, oxidative stress induced human pathologies & antioxidative therapies. The book consists of four parts in specified topics based on the current literatures for the better understanding of the readers with respect to their subject-wise interests. The first section of the book provides an overview about the ROS production and their measuring tools and techniques followed by the mechanisms involved in the oxidative stress in the second section. The third section describes the involvement of oxidative stress in different human diseases and the last section focuses on the different strategies to ameliorate oxidative stress induced stress.
Oxidative Stress And Antioxidant Protection
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Author : Donald Armstrong
language : en
Publisher: John Wiley & Sons
Release Date : 2016-04-11
Oxidative Stress And Antioxidant Protection written by Donald Armstrong and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-11 with Science categories.
Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.
Free Radicals In Brain Physiology And Disorders
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Author : Lester Packer
language : en
Publisher:
Release Date : 1996
Free Radicals In Brain Physiology And Disorders written by Lester Packer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
Covering the role of free radicals in a host of brain disorders, including Parkinson's disease, epilepsy and Alzheimer's disease, this text introduces approaches to the prevention and treatment of free radical-related neurological disorders, based on antioxidants and spin trappers.
Oxygen Free Radicals In Tissue Damage
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Author : TARR,M.
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Oxygen Free Radicals In Tissue Damage written by TARR,M. and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
Oxygen free radicals and other reactive oxygen species are being postulated as causal agents in an increasing number of pathological conditions. Indeed, some investigators are suggesting that highly destructive reactive oxygen species are the final common path lead ing to tissue damage following a wide variety of insults including trauma, hypoxia, ischemia, hyperoxia, radiation, some toxins, and even strenuous athletic pursuits. But, as Robert Floyd points out, "Proof of the importance of oxygen free radicals and the oxidative damage they initiate depend on unequivocal evidence for the pres ence of free radicals and a clear association of their formation with the induction of the dysfunction of pathological conditions. " Since such proof does not come easily, there have been and will continue to be many controversies regarding the role played by reactive oxygen species in tissue damage. There have been many recent reviews of the chemistry and pos sible role of reactive oxygen species in many types of organ dys functions, tissue damage, degenerative diseases, and aging. This book is not such a review. Rather it presents for a diverse audience of physical-organic chemists, biochemists, medical researchers, and other investigators of pathophysiology, discussions of a variety of is sues important for understanding reactive oxygen species and their role in tissue damage.
Free Radicals In Brain Pathophysiology
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Author : Giuseppe Poli
language : en
Publisher: CRC Press
Release Date : 2000-02-25
Free Radicals In Brain Pathophysiology written by Giuseppe Poli and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-02-25 with Medical categories.
This volume provides an authoritative, comprehensive view of the most current issues in brain pathophysiology and offers a critical evaluation of antioxidant-based therapeutic approaches to neurodegeneration, providing an up-to-date account of the role of antioxidants in the prevention and moderation of clinical symptoms. Examines free radicals in spinal cord damage, subarachnoid hemorrhage, reperfusion damage, and cytotoxicity! With over 2400 references, tables, drawings, photographs, and micrographs, Free Radicals in Brain Pathophysiology focuses on important biological signaling molecules such as superoxide anion and nitric oxide evaluates the action of low levels of oxygen- and nitrogen-centered radicals on cell membranes and receptors to modulate signal transduction pathways and gene expression links high mitochondrial density in neural tissue to brain disease considers how prions and -amyloid proteins influence the level of free radicals within cells assesses the abnormalities of superoxide dismutase in the familial form of amyotrophic lateral sclerosis highlights the occurrence of oxidative stress and the impact of oxidative injury in brain physiology and neurodegeneration and more! With contributions from nearly 70 internationally recognized researchers, physiologists, and clinicians who describe their latest findings and provide new insights into the factors underlying neurological disorders, Free Radicals in Brain Pathophysiology is an unsurpassed reference for nutritionists and dietitians, clinical neurologists, pathologists, cell biologists and biochemists, cardiologists, oncologists, dermatologists, and graduate and medical school students in these disciplines.
Free Radicals And Diseases
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Author : Tilman Grune
language : en
Publisher: IOS Press
Release Date : 2005
Free Radicals And Diseases written by Tilman Grune and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Active oxygen categories.