Freeze Drying Of Pharmaceutical And Food Products
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Freeze Drying Of Pharmaceutical And Food Products
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Author : Tse-Chao Hua
language : en
Publisher: Elsevier
Release Date : 2010-07-30
Freeze Drying Of Pharmaceutical And Food Products written by Tse-Chao Hua and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-30 with Technology & Engineering categories.
Freeze-drying is an important preservation technique for heat-sensitive pharmaceuticals and foods. Products are first frozen, then dried in a vacuum at low temperature by sublimation and desorption, rather than by the application of heat. The resulting items can be stored at room temperature for long periods. This informative text addresses both principles and practice in this area. The first chapter introduces freeze-drying. The authors then review the fundamentals of the technique, heat-mass transfer analyses, modelling of the drying process and the equipment employed. Further chapters focus on freeze-drying of food, freeze-drying of pharmaceuticals and the protective agents and additives applied. The final chapter covers the important subjects of disinfection, sterilization and process validation. Freeze-drying of pharmaceutical and food products is an essential reference for food, pharmaceutical and refrigeration engineers and scientists with an interest in preservation techniques. It will also be of use to students in these fields. Addresses the principles and practices used in this important preservation technique Explains the fundamentals of heat-mass transfer analysis, modelling and the equipment used Discusses the importance of disinfection, sterilization and process validation
Spray Freeze Drying Of Foods And Bioproducts
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Author : S. Padma Ishwarya
language : en
Publisher: CRC Press
Release Date : 2022-04-08
Spray Freeze Drying Of Foods And Bioproducts written by S. Padma Ishwarya and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-08 with Medical categories.
Spray-freeze-drying (SFD) is a synergistic drying technology that imbibes in it the merits of both spray drying and freeze-drying, whilst overcoming the limitations of these predecessor technologies. SFD produces uniquely powdered food and pharmaceutical products with porous microstructure and superior quality attributes. Owing to its atomization step and ultra-low-temperature operation, SFD is a competent drying technique for the production of valuable but sensitive bioactive components. Despite the costs and complexities involved, SFD has a competitive edge over the conventional drying techniques in providing distinctive product attributes. The applications of spray-freeze-drying in the area of food and bioproducts span across the product categories of instant food powders, dry flavors, active pharmaceutical ingredients, poorly water-soluble drugs, probiotics, proteins, enzymes and vaccines. Spray-Freeze-Drying of Foods and Bioproducts: Theory, Applications and Perspectives is the first exclusive title on this interesting drying technique. It provides a comprehensive understanding of the fundamentals of SFD and its food and pharmaceutical applications. The scope of this book, comprising 12 chapters, has been organizedunder four major headings: fundamentals of process-stages, applications with case-studies, recent advancements and the processing bottlenecks and solutions. Key Features Provides examples and case studies of nuances and intricacies associated with each stage of the spray-freeze-drying process Highlights the applications of spray-freeze-drying in the production of food products including soluble coffee, dairy powders, probiotics and flavors Serves as a ready-reckoner of characterization methods for spray-freeze-dried products Contains 200+ illustrations and tabulations The contents of this book are organized to cater to the knowledge needs of students, academicians, researchers and professionals in the food and pharmaceutical industry.
Freeze Drying Of Pharmaceuticals And Biopharmaceuticals
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Author : Felix Franks
language : en
Publisher: Royal Society of Chemistry
Release Date : 2008
Freeze Drying Of Pharmaceuticals And Biopharmaceuticals written by Felix Franks and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
Aimed at product and process developers in the biopharmaceutical industry and academia, this is the first book to describe freeze-drying, as related to the pharmaceutical industry.
Freeze Drying
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Author : Georg-Wilhelm Oetjen
language : en
Publisher: John Wiley & Sons
Release Date : 2008-01-08
Freeze Drying written by Georg-Wilhelm Oetjen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-08 with Science categories.
Many modern pharmaceutical and biological products, e.g. blood derivatives, vaccines, cytostatic drugs, antibiotics, bacteria cultures but also consumer goods such as soluble coffee are freeze-dried to transform perishable substances into a form that can be stored and reconstituted to their almost original state without loss of quality. The book describes the up-to-date fundamentals of freeze-drying, not just presenting the process in all its seven steps theoretically, but explaining it with many practical examples. Many years of experience in freeze-drying allow the authors to supply valuable criteria for the selection of laboratory, pilot and production plants, discussing the advantages, drawbacks and limitations of different plant designs. In this second, completely revised edition, process and plant automation are introduced in a separate section and methods to transfer pilot plant qualifications and process data to production are presented. The guidelines for process and plant evaluation and qualifications have been updated and enlarged. Trouble shooting is concentrated in a section of its own and literature has been updated with 100 new quotations to include references as recent as 2002, and 100 new tables and figures have been added.
Freeze Drying Of Pharmaceutical Products
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Author : Davide Fissore
language : en
Publisher: CRC Press
Release Date : 2019-10-24
Freeze Drying Of Pharmaceutical Products written by Davide Fissore and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-24 with Medical categories.
Freeze Drying of Pharmaceutical Products provides an overview of the most recent and cutting-edge developments and technologies in the field, focusing on formulation developments and process monitoring and considering new technologies for process development. This book contains case studies from freeze dryer manufacturers and pharmaceutical companies for readers in industry and academia. It was contributed to by lyophilization experts to create a detailed analysis of the subject matter, organically presenting recent advancements in freeze-drying research and technology. It discusses formulation design, process optimization and control, new PAT-monitoring tools, multivariate image analysis, process scale-down and development using small-scale freeze-dryers, use of CFD for equipment design, and development of continuous processes. This book is for industry professionals, including chemical engineers and pharmaceutical scientists.
Freeze Drying Lyophilization Of Pharmaceutical And Biological Products
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Author : Louis Rey
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Freeze Drying Lyophilization Of Pharmaceutical And Biological Products written by Louis Rey and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
Freeze-drying, or lyophilization, is a well established technology used in the preservation of numerous pharmaceutical and biological products. This highly effective dehydration method involves the removal of water from frozen materials via the direct sublimation of ice. In recent years, this process has met with many changes, as have the regulatio
Freeze Drying Of Food Products
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Author : Roji Balaji Waghmare
language : en
Publisher: John Wiley & Sons
Release Date : 2024-04-08
Freeze Drying Of Food Products written by Roji Balaji Waghmare and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-08 with Technology & Engineering categories.
An accessible guide to safely dehydrating food Freeze drying, or lyophilization, is a method for dehydrating food or other substances through the use of pressure instead of heat. This allows for the preservation and storage of high-value food products without altering their essential properties or causing a reduction in quality or value. For these reasons, freeze drying is the most reliable method for preserving and distributing high-quality products. Freeze Drying of Food Products provides a concise, accessible overview of freeze-drying techniques and their modern applications. Beginning with the basic principles and processes of freeze drying, it incorporates specific discussion of freeze-drying different categories of food products, before moving to an analysis of recent developments in freeze-drying technology. The result is a key publication in the fight to extend the shelf-life of food products and expand the distribution of high-quality freeze-dried foods. Freeze Drying of Food Products readers will also find: An editorial team with a wide range of pertinent research experience Detailed discussion of different freeze-drying processes such as vacuum drying, atmospheric drying, and spray drying Commercial Applications of freeze-dried food products Freeze Drying of Food Products is ideal for researchers and industry professionals involved in food production, food distribution, or food biotechnology, as well as students studying these and other related fields.
Drying Technologies For Biotechnology And Pharmaceutical Applications
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Author : Satoshi Ohtake
language : en
Publisher: John Wiley & Sons
Release Date : 2020-06-02
Drying Technologies For Biotechnology And Pharmaceutical Applications written by Satoshi Ohtake and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-02 with Medical categories.
A comprehensive source of information about modern drying technologies that uniquely focus on the processing of pharmaceuticals and biologicals Drying technologies are an indispensable production step in the pharmaceutical industry and the knowledge of drying technologies and applications is absolutely essential for current drug product development. This book focuses on the application of various drying technologies to the processing of pharmaceuticals and biologicals. It offers a complete overview of innovative as well as standard drying technologies, and addresses the issues of why drying is required and what the critical considerations are for implementing this process operation during drug product development. Drying Technologies for Biotechnology and Pharmaceutical Applications discusses the state-of-the-art of established drying technologies like freeze- and spray- drying and highlights limitations that need to be overcome to achieve the future state of pharmaceutical manufacturing. The book also describes promising next generation drying technologies, which are currently used in fields outside of pharmaceuticals, and how they can be implemented and adapted for future use in the pharmaceutical industry. In addition, it deals with the generation of synergistic effects (e.g. by applying process analytical technology) and provides an outlook toward future developments. -Presents a full technical overview of well established standard drying methods alongside various other drying technologies, possible improvements, limitations, synergies, and future directions -Outlines different drying technologies from an application-oriented point of view and with consideration of real world challenges in the field of drug product development -Edited by renowned experts from the pharmaceutical industry and assembled by leading experts from industry and academia Drying Technologies for Biotechnology and Pharmaceutical Applications is an important book for pharma engineers, process engineers, chemical engineers, and others who work in related industries.
Freeze Drying Or Lyophilization
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Author : Muhammad Waseem Akbar
language : en
Publisher:
Release Date : 2020-12-31
Freeze Drying Or Lyophilization written by Muhammad Waseem Akbar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-31 with categories.
Book DescriptionFreeze drying has many applications in the Food and Pharmaceutical industry. This book is an authentic and supreme emblem of quality that covers the basic concepts related to the lyophilization process. Review of almost all the relevant books and scientific journals is made to make the book error-free. Specifically, this book focusses on the freeze-drying process and their operating parameters for the agricultural products. I want to especially thanks to Prof. Dr Yongbin Han, Department of Agricultural Products Processing and Storage Engineering, School of Food Science and Technology, Nanjing Agricultural University, China; to help me to complete this book.Key Features: -Introduction to Freeze Drying Technique-Defining of all related Process Parameters and Variables-Recent Researches in the Freeze-Drying Field-Chemistry of Agricultural Products and their Thermal Properties-Disadvantages of Freeze-Drying Technique-Different Mathematical Models proposed by different Researchers and their ComponentsWhat will you learn?After reviewing this book, you will be able to understand the freeze-drying technique and all related terminologies. Raw material treatment, it's freezing, primary and secondary drying; all these operations should be carried out under critical considerations to dry the product efficiently. Product quality is the ultimate goal in this process and it can best achieve using freeze-drying. Thermal properties and the nature of the raw material may change the operating parameters for each of the product. But specifically, this book focuses on the freeze-drying process for agricultural products.Who is this Book for?This book is for: -Food Engineers -Freeze-drying researchers-Chemical Engineers (Those who are serving food industries as lab chemist, QC officers, and R&D officers) -Food nutritionists -Food professionals (Those who are working in food industries in freeze-drying related departments as quality officers, lab supervisors, product development officers, product audit chemists, and vicinities) -Food production compliance staff Table of Contents -Abstract-Introduction to Freeze Drying-Chemistry of Agricultural Products-Freeze Drying Stages-Freeze Drying Process Parameters -Thermal Properties of food-Disadvantages of Freeze-Drying Process-Components of Freeze Dryer-Mathematical Modeling-Conclusion-Nomenclature-ReferencesAbout this AuthorMuhammad Waseem Akbar is a food engineer by education. He is expert in nutritional, health and processing courses. Drying is a preservation technique. He has a special interest in the freeze-drying technique. This is one of the most emerging drying technique and has the potential to produce quality products with an extended shelf life for years. The author has written multiple books in the food science and engineering domain.
Spray Drying Techniques For Food Ingredient Encapsulation
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Author : C. Anandharamakrishnan
language : en
Publisher: John Wiley & Sons
Release Date : 2015-07-23
Spray Drying Techniques For Food Ingredient Encapsulation written by C. Anandharamakrishnan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-23 with Technology & Engineering categories.
Spray drying is a well-established method for transforming liquid materials into dry powder form. Widely used in the food and pharmaceutical industries, this technology produces high quality powders with low moisture content, resulting in a wide range of shelf stable food and other biologically significant products. Encapsulation technology for bioactive compounds has gained momentum in the last few decades and a series of valuable food compounds, namely flavours, carotenoids and microbial cells have been successfully encapsulated using spray drying. Spray Drying Technique for Food Ingredient Encapsulation provides an insight into the engineering aspects of the spray drying process in relation to the encapsulation of food ingredients, choice of wall materials, and an overview of the various food ingredients encapsulated using spray drying. The book also throws light upon the recent advancements in the field of encapsulation by spray drying, i.e., nanospray dryers for production of nanocapsules and computational fluid dynamics (CFD) modeling. Addressing the basics of the technology and its applications, the book will be a reference for scientists, engineers and product developers in the industry.