Fuct
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Glycoimmunology 2
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Author : John S. Axford
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Glycoimmunology 2 written by John S. Axford and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The Jenner International Glycoimmunology Meetings have charted the rapid devel opment of glycobiology within the field of inflammation. In less than a decade, the science has grown from basically being involved in carbohydrate analysis to the understanding of how sugars are associated with inflammation and how they have potential as anti inflammatory therapeutics. The 4th Jenner International Glycoimmunology Meeting was re cently held in Loutraki, Greece, and set the scene for what promises to be an exciting future for the speciality. Discussion reflected the rapid advances glycobiology is making and ranged from the basic biochemistry of carbohydrate physiology to therapeutic trials utilizing synthetic sugars designed to block inflammatory responses. The meeting is summarized in considerable detail in this book which will provide the interested scientist and clinician with the essential up-to-date facts within the field of glyco immunology. Acknowledgments Many people have been involved in ensuring the success of the Jenner Glycoimmu nology Meetings but none more so than my secretary Susan Henderson who has borne the brunt of all four meetings and is currently preparing for the 5th.
Endothelial Cells In Health And Disease
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Author : William C. Aird
language : en
Publisher: CRC Press
Release Date : 2005-02-28
Endothelial Cells In Health And Disease written by William C. Aird and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-02-28 with Medical categories.
This reference serves as the first source to gather current data from endothelial cell biologists in various disciplines to summarize recent progress in the field-providing a complete understanding of the endothelium in health and disease and demonstrating its potential as a therapeutic target.
Glycosciences
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Author : Hans-Joachim Gabius
language : en
Publisher: John Wiley & Sons
Release Date : 2008-09-26
Glycosciences written by Hans-Joachim Gabius and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-26 with Science categories.
A comprehensive survey of the topic, ranging from basic molecular research to clinical applications. Critical reviews by leading experts in each field summarize the state of knowledge and discuss the anticipated benefits of novel approaches and strategies. These include the impact of modern analysis techniques on glycobiology, the use of synthetic neoglycoproteins, or the clinical consequences of new insights into the physiological role of lectins and glycoconjugates in pathology, oncology, immunity, neuroscience and reproduction medicine. Throughout, the aim is to separate realistic applications from mere hopes.
Vi International Symposium On Inflammatory Bowel Diseases
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Author : D. Rachmilewitz
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-06-30
Vi International Symposium On Inflammatory Bowel Diseases written by D. Rachmilewitz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-06-30 with Medical categories.
This book, the proceedings of Falk Symposium No. 123, VI International Symposium on Inflammatory Bowel Diseases, held in Istanbul, Turkey, on September 3-5, 2001, focuses on the issues and controversies pertinent to IBD in the 21st century. The achievements in medical, surgical, and in the basic sciences in the last twenty years since the first Jerusalem IBD Symposium are summarized in detail. Controversies with respect to the medical treatment of inflammatory bowel diseases are discussed. One section deals with surgical issues such as laparoscopic surgery in inflammatory bowel diseases, ileo-anal pouches and the surgical treatment of Crohn's disease. The last section is devoted to the biological treatment of IBD and to the needs both in medical science and in the clinic.
The Molecular Immunology Of Complex Carbohydrates 3
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Author : Albert M. Wu
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-05-27
The Molecular Immunology Of Complex Carbohydrates 3 written by Albert M. Wu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-27 with Medical categories.
Based on the third symposium on “Molecular Immunology of Complex Carbohydrates,” this text covers the latest in glycotopes, structures and functions of complex carbohydrates, recognition factors of lectins, biomolecular interactions and other glycosciences. This volume highlights the informative events of the Symposium on Molecular Immunology of Complex Carbohydrates III, held at the Institute of Biological Chemistry, Academia Sinica, on July 15-20, 2007, in Taipei, Taiwan.
Leukocyte Trafficking
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Author : Alf Hamann
language : en
Publisher: John Wiley & Sons
Release Date : 2006-05-12
Leukocyte Trafficking written by Alf Hamann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-12 with Medical categories.
Written by known specialists in the field, this is a comprehensive and timely overview of a central and expanding topic. Simultaneously an introduction and a description of the latest concepts, findings and methods, the handbook provides basic knowledge on technical issues required for those intending to research in the field. It covers the functional role of involved molecules and the cellular mechanisms, and addresses selected examples for their possible application in therapy -- bridging the gap between trafficking mechanisms and novel therapeutic strategies. In addition, it includes selection of proven and timesaving methods for studying cell trafficking in vitro and in vivo. The accompanying CD-ROM makes leukocyte migration videos available to a broad audience for the first time.
Lymphocyte Homing To The Skin
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Author : Wolf-Henning Boehncke
language : en
Publisher: CRC Press
Release Date : 2004-12-28
Lymphocyte Homing To The Skin written by Wolf-Henning Boehncke and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-12-28 with Medical categories.
Over the last decade, enormous progress in the understanding of T-cell homing has made it possible to identify the multitude of molecules involved, such as cytokines, chemokines, and adhesion molecules, and to unravel their complex interactions resulting in controlled, non-random T-cell recirculation. These insights are now being explored therapeutically, with several compounds close to approval. Highlighting key findings in the field, Lymphocyte Homing to the Skin: Immunology, Immunopathology, and Therapeutic Perspectives brings insight to the physiology and pathophysiology of T-cell homing as a process, as well as to the manipulation of this process for therapeutic benefit. The book begins with a review of the role of T-lymphocytes in skin biology, followed by coverage of the process of lymphocyte recruitment, and lymphocyte homing to the skin. Subsequent chapters describe in vitro techniques to investigate lymphocyte extravasation, in vivo methods to study lymphocyte homing to the skin, and cutaneous T-lymphocytic infiltrates in skin pathology. The text concludes with discussions on translating cutaneous T-cell recruitment to patients. Providing a timely update on T-cell homing, this book clarifies our understanding of this complex process and offers guidance on potential therapies. It fulfills the needs of those involved in skin biology, skin toxicology, and dermatology, and proposes new directions for innovative research.
Leucocyte Trafficking
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Author : A. Hamann
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-10-07
Leucocyte Trafficking written by A. Hamann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-10-07 with Medical categories.
An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.
Handbook Of Carbohydrate Engineering
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Author : Kevin J. Yarema
language : en
Publisher: CRC Press
Release Date : 2005-05-27
Handbook Of Carbohydrate Engineering written by Kevin J. Yarema and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-27 with Medical categories.
The Handbook of Carbohydrate Engineering provides an overview of the basic science, theory, methods, and applications of this broad, interdisciplinary field. The text provides background information along with practical knowledge for current and future research methodologies used in the characterization and synthesis of various carbohydrates. This multidisciplinary perspective involves aspects of basic biology, synthetic chemistry, enzymology, complex instrumentation, and sophisticated modeling. The book presents the fundamentals of carbohydrate engineering, addressing concepts in structure, biosynthesis, and biological functions for a variety of carbohydrates with a particular emphasis on mammalian glycoproteins and their N-linked oligosaccharides, glycolipids, sialic acid, as well as polysaccharides from both eukaryotes and bacteria. It describes glycosylation processes found in nature and surveys methods to manipulate these metabolic systems in living cells both for the improved production of carbohydrates and to give these molecules novel properties. Subsequent sections discuss the various methods of purification, synthesis, modification, and analysis used to create and manipulate carbohydrates in the laboratory; these approaches include chemical-enzymatic synthesis, small-molecule cell-based strategies, as well as complete chemical synthesis. The Handbook of Carbohydrate Engineering also focuses on practical applications for carbohydrates. It emphasizes methods to characterize glycosylation pathways and expounds upon the role of carbohydrates in health and disease, a significant - and rapidly growing - area of research. World-renowned experts discuss biomedical applications, including the development of vaccines, therapeutics, glycomimetics, antibody engineering, drug delivery, tissue engineering and organ regeneration, and diagnostic agents. Several chapters also cover important applications in agriculture, industry, food technology, and environmental remediation.
Glycomics
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Author : Minoru Fukuda
language : en
Publisher: Elsevier
Release Date : 2006-11-13
Glycomics written by Minoru Fukuda and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-13 with Science categories.
In the past decade, there has been an explosion of progress in understanding the roles of carbohydrates in biological systems. This explosive progress was made with the efforts in determining the roles of carbohydrates in immunology, neurobiology and many other disciplines, examining each unique system and employing new technology. This volume represents the second of three in the Methods in Enzymology series, including Glycobiology (vol. 415) and Functional Glycomics (vol. 417), dedicated to disseminating information on methods in determining the biological roles of carbohydrates. These books are designed to provide an introduction of new methods to a large variety of readers who would like to participate in and contribute to the advancement of glycobiology. The methods covered include structural analysis of carbohydrates, biological and chemical synthesis of carbohydrates, expression and determination of ligands for carbohydrate-binding proteins, gene expression profiling including micro array, and generation of gene knockout mice and their phenotype analyses.