Gamma Hydroxybutyrate
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Gamma Hydroxybutyrate
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Author : Godfrey Tunnicliff
language : en
Publisher: CRC Press
Release Date : 2002-08-01
Gamma Hydroxybutyrate written by Godfrey Tunnicliff and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-08-01 with Medical categories.
Gamma-hydroxybutyrate (GHB) has come a long way since early experiments in animals where it was found to induce a sleep-like state and from its use in general anaesthesia in human subjects. It has been found to be a naturally-occurring compound in the brain, a metabolite of GABA, the emerging ubiquitous inhibitory neurotransmitter. This has opened
Ghb Guide Gamma Hydroxybutyrate
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Author : Esther Hansen
language : en
Publisher: Independently Published
Release Date : 2024-01-15
Ghb Guide Gamma Hydroxybutyrate written by Esther Hansen and has been published by Independently Published this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-15 with Psychology categories.
GHB Guide (Gamma hydroxybutyrate): A Definitive Guide and Safety Information, Technical Details, and GHB Spec. Along with MDMA, gamma hydroxybutyrate, often known as GHB, has earned a reputation as a "party drug," even though it is associated with several significant hazards. To present you with the most accurate and objective information that is possible, we will examine GHB from a subjective point of view in this book. A great deal of information, including the effects, the typical dosage, the potential dangers of using it, and more, will be included. Grab a copy now to learn more.
Ghb And Analogs
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Author : Marie E. Wolf
language : en
Publisher: The Rosen Publishing Group, Inc
Release Date : 2006-08-15
Ghb And Analogs written by Marie E. Wolf and has been published by The Rosen Publishing Group, Inc this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-15 with Juvenile Nonfiction categories.
Examines how club drugs like GHB are abused, the effects of this abuse on society, and efforts at prevention.
Benzodiazepines And Ghb
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Author : Salvatore J. Salamone
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-09-14
Benzodiazepines And Ghb written by Salvatore J. Salamone and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-09-14 with Medical categories.
Prominent experts explain the pharmacology and metabolism of benzodiazepines (LDB) and g-hydroxybutyric acid (GHB) and offer powerful and effective methodologies that will enable better detection of these drugs in various body fluids, as well as in hair. The techniques include highly sensitive immunoassay detection of LDBs, the detection of Rohypnol® and other LDBs by mass spectrometry, and the ultrasensitive detection of GHB. State-of-the-art and highly practical, Benzodiazepines and GHB: Detection and Pharmacology offers toxicologists, forensic scientists, and clinical chemists today's most effective methods for detecting these widely abused drugs that are sometimes found associated with criminal acts.
Gamma Hydroxybutyrate Ghb
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Author : United States. Office of National Drug Control Policy
language : en
Publisher:
Release Date : 2002
Gamma Hydroxybutyrate Ghb written by United States. Office of National Drug Control Policy and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Drug abuse categories.
Gamma Hydroxybutyrate Ghb
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Author : Lesley Chickering Flaim
language : en
Publisher:
Release Date : 1999
Gamma Hydroxybutyrate Ghb written by Lesley Chickering Flaim and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Drug abuse categories.
Analysis Of Gamma Hydroxybutyrate Ghb In Beverages
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Author : Scott James Tschaekofske
language : en
Publisher:
Release Date : 2000
Analysis Of Gamma Hydroxybutyrate Ghb In Beverages written by Scott James Tschaekofske and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Gamma-hydroxybutyrate categories.
Gamma Hydroxybutyrate Ghb
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Author : Eric E. Lyng
language : en
Publisher:
Release Date : 2006
Gamma Hydroxybutyrate Ghb written by Eric E. Lyng and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Dopamine categories.
Gamma Hydroxybutyrate (GHB) is an endogenous metabolite of gamma-aminobutyric acid (GABA) and a putative neurotransmitter found in mammalian brain. The illicit use of GHB is a growing health care concern in the U.S. Low doses have euphoric and stimulatory effects while high doses act as a CNS depressant and can cause respiratory failure. In addition to fatalities and drug facilitated rape, in 2004 over 7000 GHB overdoses were reported in the U.S. Gamma Butyrolactone (GBL) and 1,4-Butanediol (1,4-BD), precursors of GHB, can cause similar effects after being converted to GHB in the body. While GHB is a Schedule I compound, recently it was given a Schedule III classification as a drug for treatment of cataplexy associated with narcolepsy. Individuals affected by the inherited disorder succinic semialdehyde dehydrogenase (SSADH) deficiency have significant elevation of GABA and GHB in body tissues, and a range of neurological complications. Currently there is no treatment option for a GHB overdose situation or for SSADH patients. GHB has been shown to inhibit striatal dopamine release leading to sedation and loss of locomotor activity in rodents. However, GHB's mechanism of action is poorly understood. This dissertation investigated acute and chronic effects of GBL, a precursor to GHB, on locomotor function and monoamine neurotransmitter metabolism in mice. Dose response studies were performed to characterize the effects of GBL. Compounds aimed at increasing central dopaminergic activity or antagonism of GABAergic activity were tested for their ability to antagonize the locomotor effects induced by GBL. In total, eight different compounds were studied of which pergolide and nomifensine were successful at antagonizing the loss of locomotor activity when administered either prior to or after GBL. Chronic administration of GBL over the course of 14 days was evaluated in mice using a rotarod system. These studies did not reveal any long term detrimental effect of GBL on locomotor function. This dissertation is the first report showing the ability of pergolide and nomifensine to antagonize the loss of locomotor activity induced by GBL. These studies provide insight into treatment options for GHB toxicity or overdose as well as for patients with SSADH deficiency.
Toxicity Gamma Hydroxybutyrate
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Author :
language : en
Publisher:
Release Date :
Toxicity Gamma Hydroxybutyrate written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
As part of an online reference on emergency medicine for medical professions, Medicine.com, Inc. provides a fact sheet written by Scott Cameron about the toxin gamma-hydroxybutyric acid (GHB). The factsheet was originally published in the September 11, 2001 issue of "eMedicine Journal." GHB is a naturally occurring compound with a structure similar to gamma-aminobutyric acid (GABA). Information about the pathophysiology of the toxin, as well as its effects on the central nervous system and the cardiovascular system is available. Cameron lists guidelines for treating patients who have taken an overdose of GHB and includes a bibliography.
The Pharmacology Of Gamma Hydroxybutyrate Ghb
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Author : Christopher J. Cording
language : en
Publisher:
Release Date : 2001
The Pharmacology Of Gamma Hydroxybutyrate Ghb written by Christopher J. Cording and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.