Genes In Health And Disease
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Transcriptomics In Health And Disease
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Author : Geraldo A. Passos
language : en
Publisher: Springer Nature
Release Date : 2022-03-07
Transcriptomics In Health And Disease written by Geraldo A. Passos and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-07 with Science categories.
The study of transcriptomics is key to understanding complex diseases. This new edition will build on the foundation of the first edition while incorporating the progress that has been made in the field of transcriptomics in the past six years, including bioinformatics for data analysis. Written by leading experts, chapters address new subjects such as methodological advances in large-scale sequencing, the sequencing of single-cells, and spatial transcriptomics. The new edition will address how transcriptomics may be used in combination with genetic strategies to identify causative genes in monogenic and complex genetic diseases. Coverage will also explore transcriptomics in challenging groups of diseases, such as cancer, inflammation, bacterial infection, and autoimmune diseases. The updated volume will be useful for geneticists, genome biologists, biomedical researchers, molecular biologists, bioinformaticians, and students, among others.
Genetic Epidemiology
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Author : Melissa A. Austin
language : en
Publisher: CABI
Release Date : 2013
Genetic Epidemiology written by Melissa A. Austin and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
Genetic epidemiology plays a key role in discovering genetic factors influencing health and disease, and in understanding how genes and environmental risk factors interact. There is growing interest in this field within public health, with the goal of translating the results into promoting health and preventing disease in both families and populations. This textbook provides graduate students with a working knowledge of genetic epidemiology research methods. Following an overview of the field, the book reviews key genetic concepts, provides an update on relevant genomic technology, including genome-wide chips and DNA sequencing, and describes methods for assessing the magnitude of genetic influences on diseases and risk factors. The book focuses on research study designs for discovering disease susceptibility genes, including family-based linkage analysis, candidate gene and genome-side association studies, assessing gene-environment interactions and epistasis, studies of Non-Mendelian inheritance, and statistical analyses of data from these studies. Specific applications of each research method are illustrated using a variety of diseases and risk factors relevant to public health, and useful web-based genetic analysis software, human reference panels, and repositories, that can greatly facilitate this work, are described.
Human Genome Epidemiology 2nd Edition
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Author : Muin Khoury
language : en
Publisher: Oxford University Press
Release Date : 2010-01-20
Human Genome Epidemiology 2nd Edition written by Muin Khoury and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-20 with Medical categories.
The first edition of Human Genome Epidemiology, published in 2004, discussed how the epidemiologic approach provides an important scientific foundation for studying the continuum from gene discovery to the development, applications and evaluation of human genome information in improving health and preventing disease. Since that time, advances in human genomics have continued to occur at a breathtaking pace. With contributions from leaders in the field from around the world, this new edition is a fully updated look at the ways in which genetic factors in common diseases are studied. Methodologic developments in collection, analysis and synthesis of data, as well as issues surrounding specific applications of human genomic information for medicine and public health are all discussed. In addition, the book focuses on practical applications of human genome variation in clinical practice and disease prevention. Students, clinicians, public health professionals and policy makers will find the book a useful tool for understanding the rapidly evolving methods of the discovery and use of genetic information in medicine and public health in the 21st century.
Genetics And Public Health In The 21st Century
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Author : Muin J. Khoury
language : en
Publisher: Oxford University Press, USA
Release Date : 2000
Genetics And Public Health In The 21st Century written by Muin J. Khoury and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Language Arts & Disciplines categories.
The first broad survey of these two fields, this book deleniates a framework for integrating advances in human genetics into public health practice.
Examining The Causal Relationship Between Genes Epigenetics And Human Health
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Author : Wambuguh, Oscar J.
language : en
Publisher: IGI Global
Release Date : 2019-03-22
Examining The Causal Relationship Between Genes Epigenetics And Human Health written by Wambuguh, Oscar J. and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-22 with Medical categories.
For as much as we know about DNA and gene expression, many more mysteries remain to be solved. Epigenetics and epigenomics seek to study heritable modifications in gene expression that do not involve underlying DNA sequences to further human health changes. Examining the Causal Relationship Between Genes, Epigenetics, and Human Health provides innovative research methods and applications of chemical activation or deactivation of genes without altering the original DNA sequence. While highlighting topics including gene expression, personalized medicine, and public policy, this book is ideal for researchers, geneticists, biologists, medical professionals, students, and academics seeking current research on the expanding fields of genomics, epigenomics, proteomics, pharmacogenomics, and genome-wide association studies.
Nutrigenomics And Proteomics In Health And Disease
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Author : Martin Kussmann
language : en
Publisher: John Wiley & Sons
Release Date : 2017-05-08
Nutrigenomics And Proteomics In Health And Disease written by Martin Kussmann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-08 with Technology & Engineering categories.
Now in a revised second edition, Nutrigenomics and Proteomics in Health and Disease brings together the very latest science based upon nutrigenomics and proteomics in food and health. Coverage includes many important nutraceuticals and their impact on gene interaction and health. Authored by an international team of multidisciplinary researchers, this book acquaints food and nutrition professionals with these new fields of nutrition research and conveys the state of the science to date. Thoroughly updated to reflect the most current developments in the field, the second edition includes six new chapters covering gut health and the personal microbiome; gut microbe-derived bioactive metabolites; proteomics and peptidomics in nutrition; gene selection for nutrigenomic studies; gene-nutrient network analysis, and nutrigenomics to nutritional systems biology. An additional five chapters have also been significantly remodelled. The new text includes a rethinking of in vitro and in vivo models with regard to their translatability into human phenotypes, and normative science methods and approaches have been complemented by more comprehensive systems biology-based investigations, deploying a multitude of omic platforms in an integrated fashion. Innovative tools and methods for statistical treatment and biological network analysis are also now included.
Nutrient Gene Interactions In Health And Disease
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Author : Naima Moustaid-Moussa
language : en
Publisher: CRC Press
Release Date : 2001-05-30
Nutrient Gene Interactions In Health And Disease written by Naima Moustaid-Moussa and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-05-30 with Medical categories.
We have come to realize that optimal nutrient intake is determined by very specific genetic messages. This realization has led to an entirely new approach to understanding nutrition - the exploration of nutrient effects on gene expression. Edited by leading experts in the field, Nutrient-Gene Interactions in Health and Disease provides an
Genome Analysis And Human Health
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Author : Leena Rawal
language : en
Publisher: Springer
Release Date : 2017-06-08
Genome Analysis And Human Health written by Leena Rawal and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-08 with Medical categories.
This book highlights selected current data and its relevance in the human health care system, offering a fundamental primer on genetics and human health. With the advent of new high-throughput technologies (for the whole genome including exome sequencing), the conventional focus on genetics and individual genes is now shifting toward the analysis of complex genes, gene-gene interactions and the association between genes and environment, including epigenetics. The rapidly changing scientific research landscape, with the ever-growing influx of data on one hand and emergence of newer and more complicated diseases on the other, has created a dilemma for researchers and caregivers, who are still hopeful that advances in genetics and genomics will provide avenues for the understanding, prevention and possible cure of human diseases. The book focuses on the interactions between genes and proteins at both the transcriptome and proteome levels, which in turn affect the human genome and health. Additionally, it covers the domain that must be explored in order to understand the gene-gene and protein-protein interactions that contribute to human health. The book offers a valuable guide for all students and researchers working in the area of molecular genetics and genomics.
Genetics Health And Society
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Author : Brea L. Perry
language : en
Publisher: Emerald Group Publishing
Release Date : 2015-07-16
Genetics Health And Society written by Brea L. Perry and has been published by Emerald Group Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-16 with Social Science categories.
This volume focuses on critical issues surrounding the intersection of genetics, health, and society. It provides a critical examination of sociological and biomedical approaches to genomics, including strengths and limitations of each perspective.
Genes Behavior And The Social Environment
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2006-12-07
Genes Behavior And The Social Environment written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-07 with Social Science categories.
Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.