Glycobiology And Human Diseases

DOWNLOAD

Download Glycobiology And Human Diseases PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Glycobiology And Human Diseases book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page

Glycobiology And Human Diseases

DOWNLOAD
Author : Gherman Wiederschain
language : en
Publisher: CRC Press
Release Date : 2016-02-22

Glycobiology And Human Diseases written by Gherman Wiederschain and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-22 with Medical categories.

This book discusses glycobiology and various forms of human diseases. Topics covered include immunoglobulins, inflammation and glycosylation, the role and therapeutic significance of natural anti-glycan antibodies in malignancies and in normal and aberrant pregnancy, identifying urinary glycans as a possible method for the diagnosis of lysosomal st

Translational Glycobiology In Human Health And Disease

DOWNLOAD
Author : Michelle Kilcoyne
language : en
Publisher: Academic Press
Release Date : 2023-11-29

Translational Glycobiology In Human Health And Disease written by Michelle Kilcoyne and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-29 with Science categories.

Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have allowed us to better interpret and realize the importance of glycobiology in human health and disease, and glycans and their associated processes have been shown to play a significant role across a variety of disease types. As the biomedical sciences continue to adopt multi-omic and precision medicine approaches, a greater understanding of glycobiology is essential for maintaining healthy physiology and advancing disease treatment.Translational Glycobiology in Human Health and Disease offers a deep examination of glycobiology for experts and non-experts alike in areas ranging from the role of glycobiology in chronic and infectious diseases to advances in technologies for higher throughput analysis and diagnosis. While keeping human health in the forefront, this book integrates a thorough discussion of glycobiology fundamentals with its growing areas of application and societal impact. With emphasis throughout on the interdisciplinary nature of glycosciences, this book also features perspectives from the health, computational (glycoanalytics), materials, biopharmaceutical, and diagnostic sciences.Disease and speciality areas addressed include gycoimmunology, neuroglycobiology, commensal glycobiology, gut health, regenerative medicine and glycobiology, glycobiology and cancer, congenital disorders of glycosylation, infectious disease glycobiology, and parasite glycobiology. Computational approaches discussed, supporting the advance of new research, include advanced glycoanalytics, glycomics microarrays, glycoengineering, and glycol systems biology. Additionally, authors consider impact areas for society and public health, such as glycobiology and entrepreneurship, policy and regulatory requirements for glycosylation, future research, and translation to new diagnostics and drug discovery. Provides a deep, foundational overview of glycoscience and its translational potential, highlighting glycobiology’s growing role in human health and disease study Examines a broad range of relevant disease areas and applications of glycobiology in policy and public health Features chapter contributions from leading, international experts in the field, fully integrating perspectives from the health, computational, materials, biopharmaceutical, and diagnostic sciences

Essentials Of Glycobiology

DOWNLOAD
Author : Ajit Varki
language : en
Publisher: CSHL Press
Release Date : 1999

Essentials Of Glycobiology written by Ajit Varki and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.

Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

The Role Of Glycosylation In Health And Disease

DOWNLOAD
Author : Gordan Lauc
language : en
Publisher: Springer Nature
Release Date : 2021-09-08

The Role Of Glycosylation In Health And Disease written by Gordan Lauc and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-08 with Science categories.

Glycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind other areas of biology. With technological advancements growing number of glycans’ functions are being discovered and the study of glycans is becoming a cutting-edge discipline in basic and clinical research. Despite recent developments in glycobiology field, many aspects of glycosylation process still remain unknown, both in a healthy human organism and in pathological states. Human glycome is dynamic and changes with physiological triggers, immune challenges and disease. Atypical glycosylation is consequently a subject of disease biomarker research, and a target for therapeutic interventions. On the other hand, properties of glycosylated biotherapeutics are predominantly determined by their glycans. The Role of Glycosylation in Health and Disease provides a comprehensive overview of types and functions of glycans in a healthy human organism as well as their role in pathophysiology of different diseases and efficiency of glycosylated biotherapeutics. Written by the experts in the field, this book aims to bring glycobiology field closer to students, researchers in life sciences and professionals in biopharmaceutical industry.

Glycoproteins And Human Disease

DOWNLOAD
Author : Inka Brockhausen
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-21

Glycoproteins And Human Disease written by Inka Brockhausen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Science categories.

Diverse alterations of glycosylation occur in diseases such as cancer, metastasis, leukemia, inflammatory and other diseases. The glycosylation abnormalities found in disease are the result of complex rearrangements of the oligosaccharide assembly by glycosyltransferases. This volume reviews several mechanisms that may underly the extremely complex alterations in disease. Disease specific glycosylation may contribute to the disease process by altering cellular functions, or may be exploited therapeutically. Specific therapy may be aimed at correcting glycosylation abnormalities based on knowledge of the mechanisms leading to the disease phenotype and the three-dimensional interactions between carbohydrates and carbohydrate-binding molecules.

Glycobiology New Perspectives On Human Disease

DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1993*

Glycobiology New Perspectives On Human Disease written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993* with Medical microbiology categories.

Glycobiology And Medicine

DOWNLOAD
Author : John S. Axford
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Glycobiology And Medicine written by John S. Axford and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

This book contains the Proceedings of the Sixth Jenner Glycobiology and Medicine Symposium, held 14-17 September, 2002, in Seillac, France. This book highlights the latest developments in glycoimmunology, including glycosylation-dependent bacterial and viral infections, lectin and proteoglycan-dependent interactions in leukocyte homing processes to lymphoid tissues and inflamed tissues, congenital defects in glycosylation of glycoproteins and glycolipids, and the role of carbohydrates in tumour development and neuropathology, including Creutzfeldt-Jakob disease.

Glycobiology Of Innate Immunology

DOWNLOAD
Author : Cheorl-Ho Kim
language : en
Publisher: Springer Nature
Release Date : 2022-03-31

Glycobiology Of Innate Immunology written by Cheorl-Ho Kim and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-31 with Science categories.

This book presents the latest knowledge and the most recent research results on glycobiology of innate immunology. Innate immunity is the crucial part of the immunological defense system that exerts their distinct functions through binding to certain functional glycoproteins. They play a role in various human diseases and also function against microbial invaders and self-associated molecular patterns. Co-regulated expression of glycan-binding is associated with many biological components such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell–cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein–carbohydrate or carbohydrate–carbohydrate interactions. This book opens by providing the key background on glycans in innate immunity and its mechanisms behind the Dendritic cell interactions during infection and inflammation are examined in depth, and the concluding chapter is devoted to signaling tumor immunotherapy. Up-to-date information is then presented on all aspects of glycan structure-recognizing signaling. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases.

Antibody Glycosylation

DOWNLOAD
Author : Marija Pezer
language : en
Publisher: Springer Nature
Release Date : 2021-10-22

Antibody Glycosylation written by Marija Pezer and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-22 with Medical categories.

This book summarizes recent advances in antibody glycosylation research. Covering major topics relevant for immunoglobulin glycosylation - analytical methods, biosynthesis and regulation, modulation of effector functions - it provides new perspectives for research and development in the field of therapeutic antibodies, biomarkers, vaccinations, and immunotherapy. Glycans attached to both variable and constant regions of antibodies are known to affect the antibody conformation, stability, and effector functions. Although it focuses on immunoglobulin G (IgG), the most explored antibody in this context, and unravels the natural phenomena resulting from the mixture of IgG glycovariants present in the human body, the book also discusses other classes of human immunoglobulins, as well as immunoglobulins produced in other species and production systems. Further, it reviews the glycoanalytical methods applied to antibodies and addresses a range of less commonly explored topics, such as automatization and bioinformatics aspects of high-throughput antibody glycosylation analysis. Lastly, the book highlights application areas ranging from the ones already benefitting from antibody glycoengineering (such as monoclonal antibody production), to those still in the research stages (such as exploration of antibody glycosylation as a clinical or biological age biomarker), and the potential use of antibody glycosylation in the optimization of vaccine production and immunization protocols. Summarizing the current knowledge on the broad topic of antibody glycosylation and its therapeutic and biomarker potential, this book will appeal to a wide biomedical readership in academia and industry alike. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Introduction To Glycobiology

DOWNLOAD
Author : Maureen E. Taylor
language : en
Publisher: Oxford University Press, USA
Release Date : 2006

Introduction To Glycobiology written by Maureen E. Taylor and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Science categories.

We are all familiar with sugar as a vital source of energy. Yet the biological importance of the sugars extends way beyond their value as a cellular fuel.Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their functions at the molecular, cellular, and organismal level. With a new two-part structure, the book leads us through the essential principles and concepts upon which the discipline is grounded,before exploring the diverse roles of sugars throughout biological systems, including development, cell signalling, and protein trafficking. It also describes the importance of glycobiology in disease, and explains how an understanding of the link between the two is enabling us to develop newtherapeutic strategies.Taking the student from the fundamental principles to the frontiers of the subject, and with more learning features to get the most from their studies, Introduction to Glycobiology remains the ideal resource for students and teachers alike.Online Resource CentreFor Lecturers:- Full Colour figures to fully engage their students during classes.For Students:- Hyperlinks to the primary literature, and full articles from appropriate OUP journals, to facilitate access to these additional resources- 3D models of key structures, to help students visualize structures, and gain a proper appreciation of the link between structure and function.- Answers to problems, to aid assessment.- Updates - surveys of key developments in the field, provided on a six-monthly basis, to maintain the currency of the resource.