Guia Para A Hist Ria E Investiga O Das Ilhas Atl Nticas

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Guia Para A Hist Ria E Investiga O Das Ilhas Atl Nticas

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Author : Alberto Vieira
language : pt-BR
Publisher:
Release Date : 1995

Guia Para A Hist Ria E Investiga O Das Ilhas Atl Nticas written by Alberto Vieira and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Archival resources categories.

Translational Medicine

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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26

Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.

Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

Peace And War

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Author : Raymond Aron
language : en
Publisher: Transaction Publishers
Release Date : 2003

Peace And War written by Raymond Aron and has been published by Transaction Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Political Science categories.

Peace and War by Raymond Aron is one of the greatest books ever written on international relations. Aron's starting point is the state of nature that exists between nations, a condition that differs essentially from the civil state that holds within political communities. Ever keeping this brute fact about the life of nations in mind and ranging widely over political history and many disciplines, Aron develops the essential analytical tools to enable us to think clearly about the stakes and possibilities of international relations. In his first section, “Theory,” Aron shows that, while international relations can be mapped, and probabilities discerned, no closed, global “science” of international relations is anything more than a mirage. In the second part, “Sociology,” Aron studies the many ways various subpolitical forces influence foreign policy. He emphasizes that no rigorous determinism is at work: politics—and thus the need for prudent statesmanship—are inescapable in international relations. In part three, “History,” Aron offers a magisterial survey of the twentieth century. He looks at key developments that have had an impact on foreign policy and the emergence of what he calls “universal history,” which brings far-flung peoples into regular contact for the first time. In a final section, “Praxeology,” Aron articulates a normative theory of international relations that rejects both the bleak vision of the Machiavellians, who hold that any means are legitimate, and the naiveté of the idealists, who think foreign policy can be overcome. This new edition of Peace and War includes an informative introduction by Daniel J. Mahoney and Brian C. Anderson, situating Aron's thought in a new post-Cold War context, and evaluating his contribution to the study of politics and international relations.

The Canary Islands After The Conquest

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Author : Felipe Fernández-Armesto
language : en
Publisher: Oxford Historical Monographs
Release Date : 1982

The Canary Islands After The Conquest written by Felipe Fernández-Armesto and has been published by Oxford Historical Monographs this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with History categories.

The Canary Islands after the Conquest The Making of a Colonial Society in the Early-Sixteenth Century

Environmental And Water Resources History

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Author : Jerry R. Rogers
language : en
Publisher:
Release Date : 2003

Environmental And Water Resources History written by Jerry R. Rogers and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Business & Economics categories.

Annotation Twenty-four contributions address the history of various government and academic organizations that have played a role in the nation's water resources and environmental activities. Papers address topics including environmental engineering history and developments, hydraulic engineering pioneers, Bureau of Reclamation history and developments, university water and hydraulic education and research, hydrology and water resource planning, and an invited paper discussing the history of life on the Coosa, Tallapoosa, Cahaba, and Alabama rivers. Six contributions discuss the formation of the Environmental and Water Resources Institute (EWRI) and the history of ASCE technical divisions and codes and standards activities. Annotation copyrighted by Book News, Inc., Portland, OR.

Envisioning An English Empire

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Author : Robert Appelbaum
language : en
Publisher: University of Pennsylvania Press
Release Date : 2012-05-23

Envisioning An English Empire written by Robert Appelbaum and has been published by University of Pennsylvania Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-23 with History categories.

Envisioning an English Empire brings together leading historians and literary scholars to reframe our understanding of the history of Jamestown and the literature of empire that emerged from it. The founding of an English colony at Jamestown in 1607 was no isolated incident. It was one event among many in the long development of the North Atlantic world. Ireland, Spain, Morocco, West Africa, Turkey, and the Native federations of North America all played a role alongside the Virginia Company in London and English settlers on the ground. English proponents of empire responded as much to fears of Spanish ambitions, fantasies about discovering gold, and dreams of easily dominating the region's Natives as they did to the grim lessons of earlier, failed outposts in North America. Developments in trade and technology, in diplomatic relations and ideology, in agricultural practices and property relations were as crucial as the self-consciously combative adventurers who initially set sail for the Chesapeake. The collection begins by exploring the initial encounters between the Jamestown settlers and the Powhatan Indians and the relations of both these groups with London. It goes on to examine the international context that defined English colonialism in this period—relations with Spain, the Turks, North Africa, and Ireland. Finally, it turns to the ways both settlers and Natives were transformed over the course of the seventeenth century, considering conflicts and exchanges over food, property, slavery, and colonial identity. What results is a multifaceted view of the history of Jamestown up to the time of Bacon's Rebellion and its aftermath. The writings of Captain John Smith, the experience of Powhatans in London, the letters home of a disappointed indentured servant, the Moroccans, Turks, and Indians of the English stage, the ethnographic texts of early explorers, and many other phenomena all come into focus as examples of the envisioning of a nascent empire and the Atlantic world in which it found a hold.

Jan Huygen Van Linschoten

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Author : Cornelis Koeman
language : en
Publisher: UC Biblioteca Geral 1
Release Date : 1984

Jan Huygen Van Linschoten written by Cornelis Koeman and has been published by UC Biblioteca Geral 1 this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with categories.

Transnational Archipelago

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Author : Luís Batalha
language : en
Publisher: Amsterdam University Press
Release Date : 2008

Transnational Archipelago written by Luís Batalha and has been published by Amsterdam University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Social Science categories.

"The island nation of Cape Verde has given rise to a diaspora that spans the four continents of the Atlantic Ocean. Migration has been essential to the island since the birth of its nation. This volume makes a significant contribution to the study of international migration and transnationalism by exploring the Cape Verdean diaspora through its geographic diversity and with a broad thematic range"--Publisher's description.

Twenty Thousand Leagues Under The Sea

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Author : Jules Verne
language : en
Publisher:
Release Date : 1887

Twenty Thousand Leagues Under The Sea written by Jules Verne and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1887 with Submarines (Ships) categories.

The Politics Of Ethnic Consciousness

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Author : C. Govers
language : en
Publisher: Springer
Release Date : 2016-04-30

The Politics Of Ethnic Consciousness written by C. Govers and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-30 with Social Science categories.

The Politics of Ethnic Consciousness criticizes essentialist and unitary notions of ethnicity and shows the complex interaction between historical processes, recent political developments and competing views within and about ethnic groups. Welcoming the social constructionist turn, the editors disagree with its overemphasis on the arbitrary character of ethnic identification and the neglect of political economy. Contributions on such diverse regions as Brazil, Ghana, Macedonia and Sri Lanka, examine the multivocal process of the construction and reconstruction of ethnic identities through time.