Handbook Of Analytical Therapeutic Drug Monitoring And Toxicology 1996
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Handbook Of Analytical Therapeutic Drug Monitoring And Toxicology 1996
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Author : Steven H.Y. Wong
language : en
Publisher: CRC Press
Release Date : 2017-11-22
Handbook Of Analytical Therapeutic Drug Monitoring And Toxicology 1996 written by Steven H.Y. Wong and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-22 with Medical categories.
Adapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice.
Handbook Of Drug Monitoring Methods
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Author : Amitava Dasgupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-05
Handbook Of Drug Monitoring Methods written by Amitava Dasgupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-05 with Medical categories.
Written in a handbook style with specific methods and tips on eliminating false positive and false negative results, this book is a practical guide to the detailed mechanisms of such occurrences.
Analytical Methods For Therapeutic Drug Monitoring And Toxicology
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Author : Q. Alan Xu
language : en
Publisher: John Wiley & Sons
Release Date : 2011-04-12
Analytical Methods For Therapeutic Drug Monitoring And Toxicology written by Q. Alan Xu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-12 with Science categories.
This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also gas chromatography (GC), immunoassay, electrophoresis, ultra performance liquid chromatography (UPLC) coupled with UV (UPLC-UV) detection and mass spectrometry (UPLC-MS/MS). With more detailed and complete summaries than sketchy and abbreviated formats used in the other books, this book provides a thorough description of method validation and results, as well as the operating parameters.
Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology
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Author : Seth Kwabena Amponsah
language : en
Publisher: Springer Nature
Release Date : 2022-10-25
Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology written by Seth Kwabena Amponsah and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-25 with Medical categories.
This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges
Therapeutic Drug Monitoring And Toxicology By Liquid Chromatography
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Author : Steven H.Y. Wong
language : en
Publisher: Routledge
Release Date : 2017-09-19
Therapeutic Drug Monitoring And Toxicology By Liquid Chromatography written by Steven H.Y. Wong and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-19 with Medical categories.
This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses.Written by authoritative contributors who bring many years of personal laboratory/clinical experience to the book, this interdisciplinary work : presents the principlesof TDM, sampling techniques, and various instrumentation topics, including computerinterfacing, mass spectrometry, fluorescence , electrochemical detection, and bloodcollection devices . .. examines six primary classes of drugs, complete with recommendedLC procedures and emphasizing recently introduced drugs and their LC analyses. .. and documents medicolegal guidelines and laboratory management considerations,providing a contemporary assessment of today's laboratory needs.The only practical, current guide available on the subject, Therapeutic Drug Monitoringand Toxicology by Li([uid Chromatography belongs in the personal libraries of clinicaland analytical chemists and biochemists, clinical pharmacologists, clinical toxicologists,clinical pathologists, immunologists, liquid chromatographers, mass spectroscopists, laboratorydirectors, laboratory instrument manufacturers , and medical technologists. Thebook is also vital supplementary reading for advanced undergraduate and graduate-levelclinical chemistry, toxicology, clinical pathology, and liquid chromatography course.
Resolving Erroneous Reports In Toxicology And Therapeutic Drug Monitoring
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Author : Amitava Dasgupta
language : en
Publisher: John Wiley & Sons
Release Date : 2012-07-02
Resolving Erroneous Reports In Toxicology And Therapeutic Drug Monitoring written by Amitava Dasgupta and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-02 with Science categories.
The tools for detecting false positives, false negatives, and interference in interactions when testing and monitoring therapeutic drug use For physicians monitoring a patient's progress, efficacy of treatment is often linked to a patient's response to medication. Determining whether a patient is taking the prescribed amount, the drug or dosage is effective, or the prescribed medication is interacting with other drugs can be determined through drug testing. Written as a guide for toxicologists, chemists, and health professionals involved in patient care, Resolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring provides an up-to-date introduction to the tests and methodologies used in a toxicology lab as well as the sources of testing error that can lead to false positives, false negatives, and unreliable conclusions of drug abuse or under use. Covering a host of common therapeutic drugs as well as specific types of interference in immunoassays used in drug testing, the book details a number of possible testing scenarios and problems as well as solutions: False positive results in immunoassays for drugs in abuse testing Interferences in immunoassays used for monitoring anticonvulsants, tricyclic antidepressants, and digoxin False positive alcohol tests using breath analyzers and automated analyzers When a toxicology report is negative in a suspected overdose patient: the world of designer drugs Effects of drug-herb interactions on therapeutic drug monitoring Pharmacogenomics and the general principles of genetic analysis Approaches for eliminating interference/discordant specimen in therapeutic drug monitoring and drugs in abuse testing What to do in case there is no readily available method for testing Complete with easy-to-read tables and flowcharts, this book helps toxicologists, clinical chemists, clinical pathologists, and forensic pathologists develop accurate, unbiased drug monitoring and toxicology reports. Health care professionals involved in patient care, especially of critically ill patients, will find this guide indispensable in making sure lab tests are reliable enough to provide high-quality care. An indispensable handbook to the entire suite of toxicology lab tests, as well as all the possible sources of testing error, Resolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring offers clear remedies for eliminating and preventing testing error.
Analytical Procedures For Therapeutic Drug Monitoring And Emergency Toxicology
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Author : Baselt RC.
language : en
Publisher:
Release Date : 1980
Analytical Procedures For Therapeutic Drug Monitoring And Emergency Toxicology written by Baselt RC. and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with categories.
Methods Of Therapeutic Drug Monitoring Including Pharmacogenetics
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Author : Georg Hempel
language : en
Publisher: Elsevier
Release Date : 2019-10-17
Methods Of Therapeutic Drug Monitoring Including Pharmacogenetics written by Georg Hempel and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-17 with Science categories.
Methods of Therapeutic Drug Monitoring Including Pharmacogenetics, Second Edition, Volume Seven in the Handbook of Analytical Separations series, covers all aspects of drug monitoring, including laboratory work, pharmacokinetic analysis and clinical aspects, thus enabling readers from different fields to understand the whole process of therapeutic drug monitoring and how to avoid common pitfalls. The book contains analytical techniques for the quantification of drugs, along with pharmacogenetic and pharmacogenomic methods. Also included are updates on sample preparation, including dried blood spot technology and microextraction methods. In addition, the book includes new drugs, such as tyrosine kinase inhibitors and the monitoring of immunosuppressant drugs. Presents a unique, interdisciplinary approach that appeals to a wide range of users Written by authors from international labs, providing a global perspective that can be applied in various regulatory environments Features additional therapeutic drugs to reflect the rising number of immunocompromised patients Includes a new mass spectroscopic methods chapter to capture the frequent use in TDM and the improved availability of LC-MS across laboratories
Analytical Procedures For Therapeutic Drug Monitoring And Emergency Toxicology
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Author : Randall C. Baselt
language : en
Publisher: CRC Press
Release Date : 1987
Analytical Procedures For Therapeutic Drug Monitoring And Emergency Toxicology written by Randall C. Baselt and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.
Procedures to determine overdosage or poisoning include: colorimetry, visible and ultraviolet spectrophotometry, mass and atomic absorption spectrometry, flame photometry, ion-specific potentiometry, graphite furnace atomic absorption, liquid chromatography and thin layer chromatography. Gas chromatography procedures include flame ionization, electron capture, nitrogen specific, and thermal conductivity.
Drug Monitoring And Clinical Chemistry
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Author : Georg Hempel
language : en
Publisher: Elsevier
Release Date : 2004-05-15
Drug Monitoring And Clinical Chemistry written by Georg Hempel and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-05-15 with Science categories.
Drug Monitoring and Clinical Chemistry, the 5th volume in the Handbook of Analytical Separations series, gives an overview about methods to analyse drugs in biological fluids. The most widely used methods to analyse drugs in biological fluids. i.e. chromatographic methods, CE and immunoassays are described in detail. For important drugs, an overview about the methods available and a comparison of the techniques should be given to enable the reader to choose the right method depending on laboratory equipment, staff, the aim of the investigation etc. Other general aspects important for conducting therapeutic drug monitoring or pharmacokinetics studies are also covered, i.e. sample preparation, validation of the analytical methods and pharmacokinetic methods for interpreting the data. Areas where therapeutic drug monitoring is used frequently such as antibiotics, immunosuppressant drugs, antipsychotic and anticancer drugs will be discussed in detail. In addition, the important field of phenotyping and genotyping for therapy optimisation with special focus on real-life applications is also covered. The book contains important information for analyst working on drug analysis in clinical chemistry, hospital pharmacists involved in therapeutic drug monitoring, other pharmacists, chemists or physicians working on pharmacokinetic studies in industry or academia. In contrast to other books in this field, this book provides up-to-date information regarding both methodology and clinical applications. For the applications, only fields are described where therapeutic drug monitoring is used in clinical routine and provides benefit to the patients. Overview of all important field where therapeutic drug monitoring is applied All relevant analytical and computational methods are discussed Written by experts with a lot of practical experience in the field