Health Risk Assessment Dermal And Inhalation Exposure And Absorption Of Toxicants
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Health Risk Assessment Dermal And Inhalation Exposure And Absorption Of Toxicants
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Author : Rhoda G.M. Wang
language : en
Publisher: CRC Press
Release Date : 2017-11-22
Health Risk Assessment Dermal And Inhalation Exposure And Absorption Of Toxicants written by Rhoda G.M. Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-22 with Medical categories.
Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK modeling, cytochrome P-450 metabolism in skin, percutaneous absorption, adverse effects, new skin models, and the role of epidemiology in assessing the hazards of toxicants. Health Risk Assessment is essential for toxicologists, environmental chemists, pharmacologists, risk assessors, and managers working in industrial, pesticide, and pharmaceutical development. The book will also benefit individuals in environmental, regulatory, and registration affairs, as well as academicians and students.
Health Risk Assessment
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Author : Rhoda G. M. Wang
language : en
Publisher: CRC PressI Llc
Release Date : 1993-01-01
Health Risk Assessment written by Rhoda G. M. Wang and has been published by CRC PressI Llc this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-01-01 with Health & Fitness categories.
1. Pharmacokinetcs, metabolism, and percutaneous penetration of the skin; 2. Route of exposure and toxicological response; 3. Dose, toxicity, and risk assessment; 4. New models in skin research.
Revival
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Author : Rhoda G.M. Wang
language : en
Publisher:
Release Date : 2018-12-31
Revival written by Rhoda G.M. Wang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-31 with categories.
SECTION 3: DOSE, TOXICITY, AND RISK ASSESSMENT -- Chapter 21 Incorporating Biological Information into the Assessment of Cancer Risk to Humans Under Various Exposure Conditions and Issues Related to High Background Tumor Incidence Rates -- Chapter 22 Phototoxicity of Topical and Systemic Agents -- Chapter 23 Techniques for Assessing the Health Risks of Dermal Contact with Chemicals in the Environment -- Chapter 24 Interspecies Extrapolation of Toxicological Data -- SECTION 4: NEW MODELS IN SKIN RESEARCH -- Chapter 25 Human Skin Xenografts to Athymic Rodents as a System to Study Toxins Delivered to or Through the Skin -- Chapter 26 The Isolated Perfused Porcine Skin Flap -- SECTION 5: EPIDEMIOLOGIC STUDIES OF ROUTE OF EXPOSURE AND HEALTH EFFECTS -- Chapter 27 Perspectives on Assessment of Risk From Dermal Exposure to Polycyclic Aromatic Hydrocarbons -- Chapter 28 The Paradox of Herbicide 2,4-D Epidemiology -- Chapter 29 A Review of Epidemiologic Studies with Regard to Routes of Exposure to Toxicants -- Index
Principles Of Characterizing And Applying Human Exposure Models
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Author : International Program on Chemical Safety
language : en
Publisher: World Health Organization
Release Date : 2005
Principles Of Characterizing And Applying Human Exposure Models written by International Program on Chemical Safety and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
The objective of this manual is to provide guidance to risk assessors on the use of quantitative toxicokinetic and toxicodynamic data to address interspecies and interindividual differences in dose and concentration-response assessment. Section 1 focuses on the relevance of this guidance in the context of the broader risk assessment paradigm and other initiatives of the International Program on Chemical Safety (IPCS) project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals. Technical background material is presented in section 2, followed by generic guidance for the development of chemical-specific adjustment factors in section 3 and accompanying summary figures. Illustrative case-studies are included in an Appendix, and a glossary of terms is also provided.--Publisher's description.
Exposure Analysis
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Author : Wayne R. Ott
language : en
Publisher: CRC Press
Release Date : 2006-10-26
Exposure Analysis written by Wayne R. Ott and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-26 with Medical categories.
Written by experts, Exposure Analysis is the first complete resource in the emerging scientific discipline of exposure analysis. A comprehensive source on the environmental pollutants that affect human health, the book discusses human exposure through pathways including air, food, water, dermal absorption, and, for children, non-food ingesti
Public Health Risk Assessment For Human Exposure To Chemicals
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Author : K. Asante-Duah
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-09-30
Public Health Risk Assessment For Human Exposure To Chemicals written by K. Asante-Duah and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-30 with Medical categories.
In fact, with the control and containment of most infectious conditions and diseases of the past millennium having been achieved in most developed countries, and with the resultant increase in life expectancies, much more attention seems to have shifted to degenerative health problems. Many of the degenerative health conditions have been linked to thousands of chemicals regularly encountered in human living and occupational/work environments. It is important, therefore, that human health risk assessments are undertaken on a consistent basis - in order to determine the potential impacts of the target chemicals on public health.
Summary Report For The Workshop On Issues Associated With Dermal Exposure And Uptake
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Author :
language : en
Publisher:
Release Date : 2000
Summary Report For The Workshop On Issues Associated With Dermal Exposure And Uptake written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Skin absorption categories.
Exposure To Contaminants In Drinking Water
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Author : Stephen S Olin
language : en
Publisher: CRC Press
Release Date : 2020-08-18
Exposure To Contaminants In Drinking Water written by Stephen S Olin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-18 with Medical categories.
Exposure to Contaminants in Drinking Water: Estimating Uptake through the Skin and by Inhalation examines the current state of science in this field by identifying and reviewing the available information resources; evaluating various models and approaches; and demonstrating the feasibility of developing estimates of the distribution of absorbed doses of contaminants in drinking water through contact with the skin and by inhalation. This book, the product of a fifteen-member expert working group convened by the Risk Science Institute of the International Life Sciences Institute under a cooperative agreement with the U.S. Environmental Protection Agency's Office of Water, includes contributions from experts in exposure modeling and measurement; water chemistry; time-activity patterns; dermal and respiratory uptake; and the use of probability distributions in characterizing exposures.
Residential Exposure Assessment
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Author : Jeffrey Driver
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Residential Exposure Assessment written by Jeffrey Driver and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Technology & Engineering categories.
Residential Exposure Assessment: A Source Book is the result of a multiyear effort known as the Residential Exposure Assessment Project (REAP) which was initiated by the Society for Risk Analysis and the International Society of Exposure Analysis. This textbook is the primary product of the REAP and it contains contributions from over 30 professionals from a variety of disciplines such as chemistry, biology, physics, engi neering, industrial hygiene, toxicology, pharmacology, and environmental law, reflecting the diverse knowledge and resources necessary to assess and manage potential exposures occurring in and around the home. Expert working groups were organized for each of the 13 chapters to address such issues as U. S. legislation relevant to products used in and around the residence, methods for measuring and modeling exposures across multiple pathways and routes, and distributional data available for key residential exposure factors. This volume is a compendium of information about predictive methods and tools, monitoring methods, data sources, and key variables that characterize exposures in the residential setting. It presents approaches for doing exposure assessments in and around all types of residences. The purpose of the Source Book is to provide a resource for use in educational programs and for "practitioners" of residential exposure assessment. Accordingly, this book is intended for risk assessors, exposure assessors, students, initi ates new to the concept of risk assessment, industrial hygienists assessing health hazards in the home, engineers, and monitoring specialists.
Risk Assessment
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Author : Peter LaGoy
language : en
Publisher: William Andrew
Release Date : 1994-12-31
Risk Assessment written by Peter LaGoy and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-12-31 with Law categories.
Site-specific risk assessment is the process of evaluating whether or not a site poses a risk to human health or the environment. The purpose of all hazardous waste site remediation is ultimately to render a site safe for human or ecological populations. Consequently, risk assessment, as the process used to measure the effectiveness of the remediation process, is critical to all hazardous waste-site work. Risk assessment at hazardous waste sites involves the use of standard approaches and assumptions in a reasoned, common sense manner. The purpose of this book is to provide practical guidance to people wishing to learn about, conduct, or use risk assessment procedures in evaluating hazardous waste sites. Critical issues, standard formulas and assumptions, and guidance on characterizing risk results in a useable manner are presented. The use of risk assessment as a key tool in selecting appropriate remedial options at hazardous waste sites is also described. Most attention is given to human health risks associated with exposure to toxic chemicals, but descriptions of the strategies used to estimate radiation health risks and to evaluate risks to the environment are also provided. Although most commonly applied to hazardous waste site remediation, the procedures outlined in this book are generally applicable to any situation involving a potential for health risks to an exposed population. This book provides guidance on the mechanics of risk assessment preparation and illustrates these approaches with examples. However, the focus of the book is on the subjective nature of risk assessment, the art rather than the science. The actual risk (i.e., the right answer) can never be known. Consequently, while it is valuable to attempt to obtain the best numeric solution, reasonableness and the application of common sense are equally important. The book therefore devotes a substantial amount of space to issues of uncertainty that are inherent in risk assessment, and the need to address this uncertainty.