Helicobacter Pylori In Human Diseases
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Helicobacter Pylori In Human Diseases
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Author : Shigeru Kamiya
language : en
Publisher: Springer Nature
Release Date : 2019-10-22
Helicobacter Pylori In Human Diseases written by Shigeru Kamiya and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-22 with Medical categories.
This book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of Helicobacter pylori, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. H. pylori is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat H. pylori using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following H. pylori infection are still not fully understood. Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists.
Helicobacter Pylori In Human Diseases
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Author : Emma O'Neill
language : en
Publisher: American Medical Publishers
Release Date : 2021-11-16
Helicobacter Pylori In Human Diseases written by Emma O'Neill and has been published by American Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-16 with Medical categories.
Helicobacter pylori is a gram-negative microaerophilic bacterium that is found in the stomach. It is associated with gastric ulcers, chronic gastritis, duodenal ulcers and stomach cancer. Almost 85% of the people infected by H. pylori do not experience symptoms and complications. Acute cases of infection may present themselves as an acute gastritis with nausea or abdominal pain. These symptoms may progress into chronic gastritis, nonulcer dyspepsia, nausea, stomach pains, bloating, belching and black stool. Infection with H. pylori is also associated with colorectal cancer and colorectal polyps. The testing for H. pylori may be done using both invasive and non-invasive methods. Stool antigen tests, blood antibody tests, carbon urea breath tests and endoscopic biopsy are the methods for detecting infections with H. pylori. Rising antibiotic resistance has also increased the demand for alternate therapeutic strategies, such as vaccinations. The standard first-line therapy for H. pylori infections consist of proton-pump inhibitors and antibiotics. This book includes some of the vital pieces of work being conducted across the world, on various topics related to Helicobacter pylori infection. It provides significant information on H. pylori to help develop a good understanding of its role in human diseases. The book is appropriate for students seeking detailed information in this domain as well as for experts.
Helicobacter Pylori New Approaches Of An Old Human Microorganism
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Author : Bruna Maria Roesler
language : en
Publisher:
Release Date : 2019
Helicobacter Pylori New Approaches Of An Old Human Microorganism written by Bruna Maria Roesler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Microbiology categories.
Helicobacter pylori is an universally distributed bacterium which affects more than half of the world population. H. pylori infection causes persistent inflammation with different clinical outcomes in humans, including chronic gastritis, peptic ulcer disease and gastric cancer. The infection has also been associated with several extradigestive disorders. In this book there is a comprehensive overview of contributors on H. pylori infection in diverse areas, including virulence factors of H. pylori and their importance for the clinical outcome of the diseases, discussions about the principal therapeutic regimens of bacterium eradication, also considering the antimicrobial resistance. H. pylori is clearly a very interesting bacteria and great studies and discussions about all its aspects are welcome to the medical and scientific communities.
Helicobacter Pylori
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Author : Bruna Maria Roesler
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-09-18
Helicobacter Pylori written by Bruna Maria Roesler and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-18 with Science categories.
Helicobacter pylori is an universally distributed bacterium which affects more than half of the world population. H. pylori infection causes persistent inflammation with different clinical outcomes in humans, including chronic gastritis, peptic ulcer disease and gastric cancer. The infection has also been associated with several extradigestive disorders. In this book there is a comprehensive overview of contributors on H. pylori infection in diverse areas, including virulence factors of H. pylori and their importance for the clinical outcome of the diseases, discussions about the principal therapeutic regimens of bacterium eradication, also considering the antimicrobial resistance. H. pylori is clearly a very interesting bacteria and great studies and discussions about all its aspects are welcome to the medical and scientific communities.
Human Diseases Of Helicobacter Pylori
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Author : Bruna Maria Roesler
language : en
Publisher:
Release Date : 2022-04-03
Human Diseases Of Helicobacter Pylori written by Bruna Maria Roesler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-03 with categories.
Molecular Mechanisms Of Inflammation Induction Resolution And Escape By Helicobacter Pylori
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Author : Steffen Backert
language : en
Publisher: Springer
Release Date : 2019-05-23
Molecular Mechanisms Of Inflammation Induction Resolution And Escape By Helicobacter Pylori written by Steffen Backert and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-23 with Medical categories.
This book focuses on immune reactions and interactions of humans with Helicobacter pylori - a human pathogen connected to gastritis, peptic ulcers and even gastric cancer. With nearly half of the world’s population colonized, it has been characterized as one of the most successful pathogens for more than 100,000 years of co-evolution with its host. The respective chapters discuss not only how H. pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations. Readers will gain essential insights into the roles of specific factors in the immune response and learn about the impact of genetic polymorphisms on the risk of gastric carcinogenesis. In addition, the book discusses the strategies used by this bacterium, which allow it to colonize specific sites in the stomach, interact with the microbiome, evade immune surveillance and undermine the resolution of inflammation during persistent infection. This volume presents a concise summary of recent advances in the areas of induction, resolution and escape of inflammation, innate and adaptive immunity, gastric disease development, as well as treatment and vaccination against H. pylori. Accordingly, it offers a valuable asset for scientists and clinicians alike.
Helicobacter Pylori
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Author : Sinead M Smith
language : en
Publisher: Humana
Release Date : 2021-03-26
Helicobacter Pylori written by Sinead M Smith and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-26 with Medical categories.
This book brings together a collection of methods for the successful detection, culture and investigation of H. pylori, and its associated diseases. Chapters guide the reader through overviews on H. pylori infection, protocols for analyzing human clinical samples, and protocols for characterizing H. pylori, its functional components and its interactions with host cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Helicobacter pylori: Methods and Protocols aims to be a useful practical guide to researchers to help further their study in this field.
Helicobacter Pylori
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Author : Shawna L. Fleming
language : en
Publisher: Infobase Publishing
Release Date : 2007
Helicobacter Pylori written by Shawna L. Fleming and has been published by Infobase Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
Describes the symptoms and effects of helicobacter pylori infections--the leading cause of stomach ulcers--the role of the bacteria in harboring other diseases, how they affect digestion, and treatment options.
Helicobacter Pylori Research
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Author : Steffen Backert
language : en
Publisher: Springer
Release Date : 2016-05-09
Helicobacter Pylori Research written by Steffen Backert and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-09 with Medical categories.
This book provides the current updated knowledge on all essential aspects in the rapidly evolving area of Helicobacter pylori research. H. pylori is a class I carcinogen and one of the most common infections in the world. While most people colonized by H. pylori will remain asymptomatic, up to 20 % of them may develop serious gastroduodenal disease such as peptic ulcers or gastric cancer. H. pylori is the only known bacterium linked to the development of cancer and consequently is an important focus of research. Outstanding international experts from diverse scientific disciplines contribute here to give detailed insights into the current understanding concerning the physiology and role of this pathogen. Both basic science and clinical research with actual practical consequences are taken into account. The chapters target microbiology, epidemiology, genetics, biochemistry, interactions with the immune system, signal transduction, pathogenic mechanisms in the gastroduodenal mucosa, gastric disease development, and therapy including antibiotics or probiotics treatment as well as vaccination strategies. This book is an important reference not only for clinicians but also microbiologists. It provides in a single volume an up-to-date summary of our current knowledge of this microbe and the multiple ways in which it impacts upon public health in all parts of the world.
Helicobacter Pylori And Gastric Cancer
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Author : Steffen Backert
language : en
Publisher: Springer Nature
Release Date : 2024-01-17
Helicobacter Pylori And Gastric Cancer written by Steffen Backert and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-17 with Medical categories.
This volume explores in detail the molecular biology, genetics and immunology of the bacterium Helicobacter pylori that causes serious gastric diseases such as gastric cancer. The book provides in-depth insights into the mechanisms of H. pylori-induced pathogenicity, gives an overview of how the bacterium colonizes the human gut, how it manages to persist in the body and which factors play a role in the development of H. pylori-induced gastric cancer. Furthermore, the interaction between the Gram-negative bacterium and the human gut microbiome is explored, and clinical management and treatment strategies to combat gastric cancer are discussed. Helicobacter pylori is an extremely successful pathogen that persistently colonizes the gut of about 50% of the world’s population. H. pylori and its human host share a long co-evolutionary relationship that dates back for at least last 100,000 years and possibly longer. Infection by this bacterium is a high-risk factor for the development of gastric diseases, including gastric cancer. Gastric cancer is associated with high morbidity and mortality and represents the 5th most common malignant tumour and the 4th leading cause of cancer-related death worldwide. H. pylori is the first bacterium that has been classified as a type-I carcinogen by the International Agency for Research on Cancer (IARC). Recent research progress identified crucial bacterial, host and environmental factors which control H. pylori-induced gastric malignancy. New studies also suggest that specific human germline mutations and other genetic aberrations have an important impact on H. pylori-induced pathology. In this volume, all these recently discovered mechanisms are reviewed in the light of gastric cancer development, and H. pylori epidemiology, virulence factors, immune evasion, pathophysiology, cancer signalling and novel therapeutic protocols are presented. This volume is aimed at researchers in the fields of immunology, genetics, microbiology and medicine who are interested in the detailed mechanisms of the pathogenicity of this carcinogenic stomach bacterium.