Heme Oxygenase
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Heme Oxygenase
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Author : Mahin D. Maines
language : en
Publisher: CRC Press
Release Date : 1992-06-16
Heme Oxygenase written by Mahin D. Maines and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-06-16 with Medical categories.
his book provides a comprehensive summary of data from basic research on characterization, regulation, and function of heme oxygenase in mammalian systems. The book also includes a major section that covers the currently used clinical methods to suppress neonatal jaundice with emphasis on the newly developed use of synthetic metalloporophyrins. This book will be welcomed by researchers and students in pharmacology, biochemistry, pharmacy, neonatology, hematology, internal medicine, and endocrinology.
Heme Oxygenase
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Author : Leo E. Otterbein
language : en
Publisher: Nova Publishers
Release Date : 2005
Heme Oxygenase written by Leo E. Otterbein and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
Heme oxygenase is an enzyme which breaks down heme, the iron-containing oxygen-carrying constituent of the red blood cells. Heme must be synthesised and degraded within an individual nucleated cell, as heme is essential for the maintenance of cellular homeostasis by sensing or using oxygen. Physiological heme degradation is catalysed by the two functional isozymes of heme oxygenase, heme oxygenase-1 (HO-1) and HO-2, yielding CO, iron, and biliverdin IX N. Heme oxygenase-1 (HO-1), has potent anti-inflammatory, anti-oxidant and anti-proliferative effects, is up-regulated by multiple stimuli and provides protection against oxidative stress. HO-1 also plays an important role in the regulation of cardiovascular function and is involved in many other diseases such as sickle cell disease. This new book brings together leading research from around the world in this field.
Heme Oxygenase In Biology And Medicine
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Author : Nader G. Abraham
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Heme Oxygenase In Biology And Medicine written by Nader G. Abraham and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Heme oxygenase is rapidly taking its place as the centerpiece of multiple inter acting metabolic systems. Only 25 years ago heme oxygenase and its metabolic prod ucts appeared to be merely a simple metabolic system-one substrate, heme; one enzyme, heme oxygenase; and one set of products, iron to be recycled, and bilirubin and carbon monoxide to be disposed. From a group of about 25 people in 1974, as judged by attendance at various Gordon conferences, heme oxygenase has, in the year 2000, attracted working scientists-and clinicians I might add-by the hundreds and has produced referenced publications by the thousands. It is well-deserved attention. Heme oxygenase system is now similar to the metabolic networks surrounding glucose in those complex maps of glycolytic and non-glycolytic metabolic pathways, which we had to memorize as students. The relevance of heme oxygenase to regulatory biology was recognized many years ago, but the work conducted over the past five years has created a new wave of emphasis focusing on genetic manipulation to alter heme oxygenase gene expression, the regulatory actions of heme oxygenase products including carbon monoxide, and the significance of changes in the heme oxygenase system. The physiological and pathological relevance of heme oxygenase in the brain, heart, liver, bone marrow, organ transplant, lung and kidney, opens many areas of investigation in various dis ciplines. Advances in the pharmacology of bilirubin and its ability as an antioxidant have provided a new avenue in clinical research.
Protective And Detrimental Role Of Heme Oxygenase 1
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Author : Valeria Sorrenti
language : en
Publisher: MDPI
Release Date : 2019-11-14
Protective And Detrimental Role Of Heme Oxygenase 1 written by Valeria Sorrenti and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-14 with Science categories.
The book “Protective and Detrimental Role of Heme Oxygenase-1”, includes a selection of original research papers and reviews aimed at understanding the dual role (protective and detrimental) of HO-1 and the involved signaling pathways. Original research papers and reviews aimed at the identification of natural molecules or new synthetic compounds able to modulate HO-1 activity/expression help make HO-1 a potential therapeutic target for the amelioration of various diseases.
Advances In Heme Oxygenase Decyclizing Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Advances In Heme Oxygenase Decyclizing Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Advances in Heme Oxygenase (Decyclizing) Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Heme Oxygenase (Decyclizing) in a concise format. The editors have built Advances in Heme Oxygenase (Decyclizing) Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Heme Oxygenase (Decyclizing) in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Heme Oxygenase (Decyclizing) Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Heme Oxygenase And The Kidney
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Author : David E. Stec
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2011
Heme Oxygenase And The Kidney written by David E. Stec and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
Heme oxygenases (HOs) are the enzymes responsible for the breakdown of heme and the generation of biliverdin/bilirubin and carbon monoxide (CO). The kidney is a complex organ consisting of many different cell types all working together for the single purpose of filtering the blood to eliminate waste products and conserving ions, minerals, and water necessary for life. HO enzymes and their products play a critical role in the normal function of the kidney as well as protecting the kidney from various insults including ischemia and exposure to nephrotoxins. For example, the HO metabolite, bilirubin, is a potent antioxidant which can limit damage to renal tubular epithelial cells following exposure to nephrotoxins associated with chemotherapy or traumatic injury. Another HO metabolite, CO, is an important vasodilator of renal blood vessels and helps protect against severe decreases in renal blood flow in conditions as diverse as exposure to radiocontrast agents and in hypertension-induced kidney disease. HO and its metabolites also play an important role in the survival of kidney cells after acute and chronic injuries by regulating important cell growth and programmed cell death pathways. The intent of this volume is to highlight the important role that HO enzymes and their related metabolites, bilirubin and CO, play in the regulation of renal function and in the response of the kidney to both acute and chronic pathologies. Table of Contents: Introduction to the HO System / HO and Renal Vascular Function / HO and Renal Tubule Function / HO and Acute Kidney Injury / HO and Chronic Kidney Injury / Future of Renal HO Research / References
Advances In Heme Oxygenase Decyclizing Research And Application 2013 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-06-21
Advances In Heme Oxygenase Decyclizing Research And Application 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-21 with Medical categories.
Advances in Heme Oxygenase (Decyclizing) Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Advances in Heme Oxygenase (Decyclizing) Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Heme Oxygenase (Decyclizing) Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Protective And Detrimental Role Of Heme Oxygenase 1
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Author : Valeria Sorrenti
language : en
Publisher:
Release Date : 2019
Protective And Detrimental Role Of Heme Oxygenase 1 written by Valeria Sorrenti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Medicine (General) categories.
The book “Protective and Detrimental Role of Heme Oxygenase-1”, includes a selection of original research papers and reviews aimed at understanding the dual role (protective and detrimental) of HO-1 and the involved signaling pathways. Original research papers and reviews aimed at the identification of natural molecules or new synthetic compounds able to modulate HO-1 activity/expression help make HO-1 a potential therapeutic target for the amelioration of various diseases.
Heme Oxygenase Ho 1 As An Immunoregulator In Health And Disease
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Author : Elias A Lianos
language : en
Publisher: Mdpi AG
Release Date : 2023-07-17
Heme Oxygenase Ho 1 As An Immunoregulator In Health And Disease written by Elias A Lianos and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-17 with Science categories.
Heme oxygenase (HO)-1 is a well-known, cytoprotective enzyme, responsible for the enzymatic conversion of heme into the anti-apoptotic and antioxidant by-products, biliverdin, bilirubin and carbon monoxide. However, HO-1 also regulates responses via mechanisms that are independent of the generation of heme degradation products. The current Special Issue contains research and review articles on the effect of heme oxygenase on immune-related cellular and physiological cascades and functions including effects on innate immunity, adaptive immunity, inflammation and complement activation. A description of the role of HO-1 in immune regulation directly or via its by-products is depicted on various forms of infection, viral and bacterial, immune-mediated injury such as renal injury, allergic airway inflammation, cancer and metabolism. Thus, the current Special Issue aims to serve as a detailed, analytical and up-to-date guide of the recent advances on the immunomodulatory properties of HO-1.
Advances In Heme Oxygenase Decyclizing Research And Application 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26
Advances In Heme Oxygenase Decyclizing Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.
Advances in Heme Oxygenase (Decyclizing) Research and Application / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Heme Oxygenase (Decyclizing) in a concise format. The editors have built Advances in Heme Oxygenase (Decyclizing) Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Heme Oxygenase (Decyclizing) in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Heme Oxygenase (Decyclizing) Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
