Hgk

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Hgk

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Author : Mes Kar
language : en
Publisher:
Release Date : 2019-11-21

Hgk written by Mes Kar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-21 with categories.

The notebook For many people, a notebook is an important part of their daily planning. No matter whether to-do lists, shopping lists or other notes, once written down you will never forget anything so quickly. And if so? - Then you know where it stands! A notebook is a book with blank pages that is used to collect ideas, comments and notes of all kinds. This notebook is lined and has 120 pages.

Head Neck Cancer And Esophageal Cancer From Biosignatures To Therapeutics

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Author : Victor C. Kok
language : en
Publisher: Frontiers Media SA
Release Date : 2021-05-11

Head Neck Cancer And Esophageal Cancer From Biosignatures To Therapeutics written by Victor C. Kok and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-11 with Medical categories.

Asian Recorder

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Author :
language : en
Publisher:
Release Date : 1999

Asian Recorder written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Asia categories.

Advances In Immunology

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Author :
language : en
Publisher: Academic Press
Release Date : 2016-01-11

Advances In Immunology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-11 with Medical categories.

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. Contributions from leading authorities Informs and updates on all the latest developments in the field

Fundamentals Of Infinite Dimensional Representation Theory

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Author : Raymond C. Fabec
language : en
Publisher: CRC Press
Release Date : 2018-10-03

Fundamentals Of Infinite Dimensional Representation Theory written by Raymond C. Fabec and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-03 with Mathematics categories.

Infinite dimensional representation theory blossomed in the latter half of the twentieth century, developing in part with quantum mechanics and becoming one of the mainstays of modern mathematics. Fundamentals of Infinite Dimensional Representation Theory provides an accessible account of the topics in analytic group representation theory and operator algebras from which much of the subject has evolved. It presents new and old results in a coherent and natural manner and studies a number of tools useful in various areas of this diversely applied subject. From Borel spaces and selection theorems to Mackey's theory of induction, measures on homogeneous spaces, and the theory of left Hilbert algebras, the author's self-contained treatment allows readers to choose from a wide variety of topics and pursue them independently according to their needs. Beyond serving as both a general reference and as a text for those requiring a background in group-operator algebra representation theory, for careful readers, this monograph helps reveal not only the subject's utility, but also its inherent beauty.

Automated Reasoning With Analytic Tableaux And Related Methods

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Author : Martin Giese
language : en
Publisher: Springer
Release Date : 2009-10-20

Automated Reasoning With Analytic Tableaux And Related Methods written by Martin Giese and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-20 with Computers categories.

This volume contains the research papers presented at the International C- ference on Automated Reasoning with Analytic Tableaux and Related Methods (TABLEAUX 2009) held July 6-10, 2009 in Oslo, Norway. This conference was the 18th in a series of international meetings since 1992 (listed on page IX). It was collocated with FTP 2009, the Workshop on First-Order Theorem Proving. The Program Committee of TABLEAUX 2009 received 44 submissions from 24 countries. Each paper was reviewed by at least three referees, after which the reviews were sent to the authors for comment in a rebuttal phase. After a ?nal intensive discussion on the borderline papers during the online meeting of the Program Committee, 21 research papers and 1 system description were accepted based on originality, technical soundness, presentation, and relevance. Additionally,three positionpaperswereaccepted,whicharepublished asate- nical report of the University of Oslo. We wish to sincerely thank all the authors who submitted their work for consideration. And we would like to thank the Program Committee members and other referees for their great e?ort and p- fessional work in the review and selection process. Their names are listed on the following pages.

Representations And Cohomology Volume 1 Basic Representation Theory Of Finite Groups And Associative Algebras

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Author : D. J. Benson
language : en
Publisher: Cambridge University Press
Release Date : 1998-06-18

Representations And Cohomology Volume 1 Basic Representation Theory Of Finite Groups And Associative Algebras written by D. J. Benson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-06-18 with Mathematics categories.

An introduction to modern developments in the representation theory of finite groups and associative algebras.

Multi Targeted Natural Products As Cancer Therapeutics Challenges And Opportunities Volume I 2nd Edition

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Author : Jiang-Jiang Qin
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-11

Multi Targeted Natural Products As Cancer Therapeutics Challenges And Opportunities Volume I 2nd Edition written by Jiang-Jiang Qin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-11 with Medical categories.

This Research Topic is part of a series with: Multi-targeted Natural Products as Cancer Therapeutics: Challenges and Opportunities, Volume II Cancer remains a leading cause of disease-related deaths worldwide, despite recent advances in our understanding of cancer initiation, progression, and metastasis. Chemotherapy and radiotherapy have been used as standard non-surgical treatments of human cancer for decades, however, the survival rates of patients with cancer, especially those with advanced diseases are still very low due to the high toxicities of these treatments as well as the severe side effects. This fact has motivated researchers to discover new cancer therapeutics with minimum side effects, which intensively promotes the rapid development of single specific molecule-targeted therapies (SSMTT). Many efforts have been made in world-wide cancer drug discovery research and several single molecule-targeted therapies have been successfully developed. Unfortunately, most of the investments failed because cancer is a genetic disease and always harbors multiple alternations of molecules or genes at the genomic, genetic and epigenetic levels. The inhibition of a single molecule or signaling pathway by SSMTT frequently results in a hyperactive compensation of other cancer-related molecules and signaling pathways as well as the subsequent development of drug resistance. Therefore, identifying multi-targeted therapies, i.e. drugs that are able to target multiple cancer-related genes, proteins, or signaling pathways is a more promising way to success in developing new cancer therapeutics. Natural products, especially those from traditional Chinese medicine and folk remedies in other countries are an extraordinarily important source for new drug discovery over the past decades. Of note, many natural products have often been demonstrated to target several crucial genes or proteins in cancer-related signaling networks and exert synergistic effects. For example, Japonicone A, a dimeric sesquiterpenoid from the medicinal plant Inula japonica, has been found to inhibit tumor growth and metastasis by dually targeting the TNF-α/NF-κB and p53/MDM2 signaling pathways. Traditionally, researchers have believed that the multi-targeting mechanisms of natural products have limited their use in cancer treatment due to the low specificity and potential side effects. The growing interest in developing multi-targeted cancer therapies may provide another golden opportunity to develop natural products as new cancer therapeutics. Nevertheless, critical investigations for a comprehensive understanding of the molecular mechanisms of natural products also mean more challenges. Our long-term goals are to fully understand the molecular targets and mechanisms of action of anticancer natural products and develop them as novel cancer preventive and therapeutic agents. The specific goal of this Research Topic is to bring together the recent findings of newly identified anticancer natural products, especially those with multiple molecular targets. Papers (Original Research articles or Reviews) which discuss the in vitro and in vivo efficacy and pharmacological and toxicological properties of natural products are also welcome to be submitted. Guidelines for the conception and review of submissions As many anticancer drugs working as cytotoxic compounds have non-selective effects annihilating their potential therapeutic benefits, manuscripts are advised to provide evidence of a significant selectivity towards cancer cells (vs. healthy cells). Specifically, if the studied anticancer drug or modality does not target an oncogenic pathway, the authors should make every effort possible to prove that the cytotoxic or cytostatic effects they have identified exhibit selectivity for cancer cells (ideally 1 log difference in EC50 or IC50) vs. non-malignant cells (eg, fibroblasts or primary culture of cells). The authors should also demonstrate the applicability of their anticancer modalities on a minimum of two well-authenticated cancer cell lines (ideally originating from distinct organs/tissues). For manuscripts dealing with plant extracts or other natural substances/compounds, the composition and the stability of the study material must be described in sufficient detail. In particular, for extracts, chromatograms with characterization of the dominating compound(s) are requested. The level of purity must be proven and included. Please refer to the Four Pillars of Best Practice in Ethnopharmacology, a subset of which concerning general standards in natural product research are applied to all such studies in all sections of Frontiers in Pharmacology.

Journal Of The North China Branch Of The Royal Asiatic Society

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Author : North China Branch of the Royal Asiatic Society
language : en
Publisher:
Release Date : 1879

Journal Of The North China Branch Of The Royal Asiatic Society written by North China Branch of the Royal Asiatic Society and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1879 with China categories.

Contains list of members.

History Of European Botanical Discoveries In China

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Author : Emil Bretschneider
language : en
Publisher: SEVERUS Verlag
Release Date : 2011

History Of European Botanical Discoveries In China written by Emil Bretschneider and has been published by SEVERUS Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.

"It has been attempted in the following pages to supply the want of a work of reference, in which botanists dealing with Chinese plants preserved in European herbariums might find some particulars regarding the history of these collections, of which the labels affixed to the herbarium specimens generally give only an imperfect account." Emil Bretschneider (1833-1901) became famous among researchers for his valuable contributions to the field of sinology. His versatile approach - he was a physician and botanist as well as a sinologist - and his familiarity with Chinese literature distinguished him from his colleagues, many of whom were unable to read sources firsthand. Combining his abilities in botany and sinology, Bretschneider comprises an extensive history of Chinese plants and how they found their way to Europe. From the earliest accounts by Marco Polo, to the groundbreaking work of Carl Linnaeus, to the period of the Opium wars between England and China, this volume covers the works of European botanists up until 1860. Bretschneider does not limit his scope to China proper, but includes Mongolia, Tibet, Korea, and other regions, making this a uniquely comprehensive guide to European research on Asian plants.