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Hirntumoren Und Spinale Tumoren


Hirntumoren Und Spinale Tumoren
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Hirntumoren Und Spinale Tumoren


Hirntumoren Und Spinale Tumoren
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Author : J.-C. Tonn
language : de
Publisher: W. Zuckschwerdt Verlag
Release Date : 2016-03-02

Hirntumoren Und Spinale Tumoren written by J.-C. Tonn and has been published by W. Zuckschwerdt Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-02 with Medical categories.


In den vergangenen Jahren hat die Neuroonkologie eine tiefgreifende Entwicklung vollzogen. Das Verständnis der Biologie vieler Tumoren ist durch die Ergebnisse der Molekularbiologie und -genetik wesentlich differenzierter geworden. So konnten durch umfangreiche Studienserien biologisch und klinisch distinkte Subgruppen identifiziert werden, so zum Beispiel bei den Medulloblastomen und den Gliomen im Erwachsenenalter. Der allgemeine Teil des Manuals stellt Grundzüge der Diagnostik und Therapie dar. Im speziellen Teil werden die einzelnen Tumorentitäten in Hinblick auf Häufigkeit, Prognose und Therapie fokussiert. Die Rehabilitation wird in einem eigenen Kapitel behandelt, ebenso wie palliativmedizinische Maßnahmen. Neben der inhaltlichen Überarbeitung und Aktualisierung wurden in der 4. Auflage des Manuals zu Beginn jedes Kapitels "Abstracts" eingeführt. "Essentials" heben die Kernaussagen einzelner Abschnitte hervor.



Hirntumoren Und Spinale Tumoren


Hirntumoren Und Spinale Tumoren
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Author : Jörg-Christian Tonn
language : de
Publisher:
Release Date : 2007

Hirntumoren Und Spinale Tumoren written by Jörg-Christian Tonn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.




Hirntumoren Und Prim Re Tumoren Des R Ckenmarks


Hirntumoren Und Prim Re Tumoren Des R Ckenmarks
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Author : Jörg-Christian Tonn
language : de
Publisher:
Release Date : 2004

Hirntumoren Und Prim Re Tumoren Des R Ckenmarks written by Jörg-Christian Tonn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.




Human Brain And Spinal Cord Tumors From Bench To Bedside Volume 1


Human Brain And Spinal Cord Tumors From Bench To Bedside Volume 1
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Author : Nima Rezaei
language : en
Publisher: Springer Nature
Release Date : 2023-01-01

Human Brain And Spinal Cord Tumors From Bench To Bedside Volume 1 written by Nima Rezaei and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-01 with Medical categories.


Brain tumors comprise about 5–9% of all human neoplasms; and interestingly the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. Besides to the morphologic and histopathologic characteristics, and as each pathologic states first starts with molecular alterations, each tumor may have its own story in the matter of activating tumorigenesis pathways and having specific molecular characteristics. Importantly, the molecular classification of tumors has been highly considered in the past few decades for taking the most appropriate therapeutic approach. On the other hand, the tumors shall have tumor-scape mechanisms preventing the immunologic system to eliminate its invasion. The failure of innate and acquired immune system to defeat tumorigenesis mechanisms would consequently result in tumor development. Interestingly, the neuro-immunologic mechanism plays a role in development of psychiatric manifestations of brain tumors as well. Taking all these to account, the different arms of innate immunity, acquired immunity, and genetics have been approached to defeat development and/or progression of such tumors. Accordingly, the activation immunotherapeutic approaches focus on activating or strengthening the anti-tumor immunologic pathways in order to assist the weakened immune system to defeat the tumor (such as Dendritic cell vaccination, DNA vaccines, peptide vaccines, viral vector-based vaccines, monoclonal antibodies, and CAR T-cell therapy). In addition to immunologic components of brain and spinal cord tumors, numerous genes and genetic pathways have been recognized to take part in tumorigenesis. Taking these non-immune genetic pathways to account, some other therapeutic approaches such as stem cell therapy and gene therapy have been developed in the new era of cancer treatment. Moreover, and besides the biologic and medical aspects of these tumors, different physical/mathematical models have been proposed to either explain or predict tumor behavior. Such models would be advantageous in developing new therapeutic modalities in pre-clinical stages and enter new eras in cancer treatment. The first book of Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics, will mainly discuss the neuro-immunology and neurogenetic pathways associated with development of brain and spinal cord tumor. After a short introduction chapter, this book will focus on the role of innate and acquired immunity on development of these tumors and then the immunotherapeutic approaches to defeat these tumorigenesis mechanisms. This book will then focus on genetic aspects of brain and spinal cord tumors and bioinformatics models to describe the behavioral patterns of these tumors, as well as associated therapeutic approaches such as stem cell therapy and gene therapy. This volume of book could be useful for experts in basic sciences, mainly geneticists and immunologists, and also physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists and neuroradiologists.



Brain And Spinal Tumors Of Childhood


Brain And Spinal Tumors Of Childhood
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Author : David A. Walker
language : en
Publisher: CRC Press
Release Date : 2020-11-11

Brain And Spinal Tumors Of Childhood written by David A. Walker and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-11 with Medical categories.


This second edition comes at a time of a paradigm shift in understanding of the molecular pathology and neuroscience of brain and spinal tumors of childhood and their mechanisms of growth within the developing brain. Excellent collaborative translational networks of researchers are starting to drive change in clinical practise through the need to test many ideas in trials and scientific initiatives. This text reflects the growing concern to understand the impact of the tumour and its treatment upon the full functioning of the child’s developing brain and to integrate the judgments of the risks of acquiring brain damage with the risk of death and the consequences for the quality of life for those who survive. Information on the principles of treatment has been thoroughly updated. A chapter also records the extraordinary work done by advocates. All medical and allied professionals involved in any aspect of the clinical care of these patients will find this book an invaluable resource.



Tumors Of The Brain And Spine


Tumors Of The Brain And Spine
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Author : Franco DeMonte
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-10

Tumors Of The Brain And Spine written by Franco DeMonte and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-10 with Medical categories.


Tumors of the Brain and Spine focuses primarily on approaches to the treatment of benign, primary low-grade to high-grade, and metastatic tumors in the brain and spine, as practiced by surgeons and clinicians at the University of Texas M. D. Anderson Cancer Center. The book is written mainly for the primary care oncologist, general neurologist, and general neurosurgeon. Discussion of treatment coverage focuses on neurosurgery, chemotherapy, and radiation therapy, singly and in combination. Also included are chapters on symptom management, molecular genetics and neuropathology of intracranial tumors, leptomeningeal dissemination of systemic cancer, epidemiology of brain tumors, and innovative treatment strategies.



Human Brain And Spinal Cord Tumors From Bench To Bedside Volume 2


Human Brain And Spinal Cord Tumors From Bench To Bedside Volume 2
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Author : Nima Rezaei
language : en
Publisher: Springer Nature
Release Date : 2023-07-15

Human Brain And Spinal Cord Tumors From Bench To Bedside Volume 2 written by Nima Rezaei and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-15 with Medical categories.


This book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients. Brain tumors comprise about 5–9% of all human neoplasms; and the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. The more we know about the nature and characteristic of brain and spinal cord tumors, the more precise decision could be made for each patient, in order to reach the best outcome. While surgical resection, chemotherapy, and radiotherapy have been considered as the standards of care for benign and/or malignant CNS tumors since a long time ago, new therapeutic approaches such as immunotherapy have been recently proposed to be considered for treatment of CNS tumors, especially as in some cases, the tumors might be inoperable or the patient may not benefit from other treatment modalities after several recurrences. The second volume of the book focuses on clinical aspects of these tumors. Accordingly, the most important brain and spinal cord tumors are specifically discussed in each chapter based on a rational outlining for all chapter in this volume: Background and epidemiology, genetics, immunology and molecular biology, histopathology and morphology, imaging and radiologic features, clinical manifestations, therapeutic approaches, surgical intervention, chemotherapy and radiotherapy, new therapeutic modalities, follow-up, and prognosis. The chapters of this volume discuss the following pathologies of brain and spinal cord tumors: malignant glioma, benign glioma, meningiomas and other meningeal tumors, ependymomas, medulloblastomas, pineal tumors, choroid plexus and ventricular tumors, neuroectodermal tumors of CNS, neuroepithelial tumors of CNS, pituitary gland tumors, craniopharyngioma, schwannomas and nerve-sheet tumors, hemangioblastomas and other vascular originating tumors, brain and spinal tumors of embryonic origin, germ line cell tumors, malignant bone or cartilage-originating tumors of brain and spine, benign bone or cartilage-originating tumors of brain and spine, brain tumors affecting the orbit globe and orbit tumors affecting the brain, CNS lymphomas, metastatic lesions of the brain and spine, malignant spinal tumors, benign spinal tumors, brain and/or spinal cord tumors accompanied with other diseases or syndromes, psychological and psychiatric aspects of brain and spinal cord tumors, a brief explanation on surgical approaches for treatment of different brain tumors. This volume of book is useful for physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists, and neuroradiologists.



Brain And Spinal Tumors Of Childhood


Brain And Spinal Tumors Of Childhood
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Author : David Walker
language : en
Publisher: CRC Press
Release Date : 2004-07-30

Brain And Spinal Tumors Of Childhood written by David Walker and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-07-30 with Medical categories.


Children with brain and spinal tumors account for 20-25% of childhood cancers. Until the early 1990s there had been little progress in the development of new treatments, and outcomes were not improving despite advances seen in other childhood cancers. During the past 10 years, however, there has been a dramatic increase in interest in the subject a



Primary Tumors Of The Brain And Spinal Cord


Primary Tumors Of The Brain And Spinal Cord
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Author : S. Clifford Schold
language : en
Publisher: Butterworth-Heinemann
Release Date : 1997

Primary Tumors Of The Brain And Spinal Cord written by S. Clifford Schold and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.


This book is a single source of information on the diagnosis and management of patients with primary central nervous system neoplasms. The audience includes neurologists, neurosurgeons, medical oncologists, radiation oncologists, and pediatric oncologists. Diagnostic methods have changed significantly in the last several years, and effective treatments have been developed for many of these patients. Much of this information is in the literature, but there is not a central source that emphasizes clinical aspects of these diseases. This book is organized by tumor type (after preliminary chapters on history, diagnosis, and general aspects of treatment), and the last chapter discusses several miscellaneous topics, including a review of the diseases that appear radiographically to be tumors but are not. The format is traditional with the figures emphasizing typical neuroimaging of these tumors, and the references are limited to key articles rather than comprehensive reviews. Several authors from different disciplines pertaining to brain tumors have contributed.



Neurosurgery Of Complex Vascular Lesions And Tumors


Neurosurgery Of Complex Vascular Lesions And Tumors
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Author : S. Kobayashi
language : en
Publisher: Thieme
Release Date : 2011-01-01

Neurosurgery Of Complex Vascular Lesions And Tumors written by S. Kobayashi and has been published by Thieme this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-01 with Medical categories.


Benefit from the expertise of world-renowned neurosurgeons, who share their strategies for managing a wide range of cerebral and spinal conditions involving vascular and tumor pathology. Presented in a case format, the book details problems, history, surgical tactics, procedures, and postoperative course, followed by a valuable section of comments from the experts. You will find insights on such complex procedures as clipping of giant intracranial aneurysms, removal of brain stem tumors, bypass surgery with radial artery graft and more. The resulting work is a compilation that explains some of the most difficult clinical problems in the field while enhancing your ability to treat more routine cases. By turning their talents to the toughest cases, Dr. Kobayashi and his colleagues have created a reference that is certain to advance the practice of neurosurgery at every level, with treatments that are more accurate, less invasive, and safe.