Hsps Ambiguous Mediators Of Immunity

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Hsps Ambiguous Mediators Of Immunity

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Author : Stuart Keith Calderwood
language : en
Publisher: Frontiers Media SA
Release Date : 2017-05-11

Hsps Ambiguous Mediators Of Immunity written by Stuart Keith Calderwood and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-11 with Electronic book categories.

Heat shock proteins (HSPs) were discovered as polypeptides induced by stress that can be found in all kingdoms of cellular organisms. Their functions were, a first enigmatic and these proteins were thus classified by molecular weight, as in—Hsp27, Hsp70, Hsp90, Hsp110. More recently, each of these size-classified molecules has attributed a role in protein folding, and they thus came to be known, as a class, as molecular chaperones. However, the they possess properties beyond chaperoning. Indeed, their discovery in the extracellular spaces suggested roles in regulation of the immune responses.

Heat Shock Proteins Potent Mediators Of Inflammation And Immunity

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Author : Alexzander A.A. Asea
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-09-05

Heat Shock Proteins Potent Mediators Of Inflammation And Immunity written by Alexzander A.A. Asea and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-05 with Medical categories.

This book provides the most up-to-date review on new mechanisms and provides exciting insights into how heat shock proteins modulate the hosts’ immune response. Written by leaders in the field of heat shock protein immunobiology, the chapters systematically and in a step-wise fashion take the reader through the fascinating sequence of events by which heat shock proteins activate immune responses and provide answers as to its biological significance to the host.

Cellular Stress And Inflammation How The Immune System Drives Tissue Homeostasis

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Author : Fabrizio Antonangeli
language : en
Publisher: Frontiers Media SA
Release Date : 2021-05-10

Cellular Stress And Inflammation How The Immune System Drives Tissue Homeostasis written by Fabrizio Antonangeli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-10 with Medical categories.

Updates In The Diagnosis And Treatment Of Vasculitis

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Author : Lazaros Sakkas
language : en
Publisher: BoD – Books on Demand
Release Date : 2013-02-20

Updates In The Diagnosis And Treatment Of Vasculitis written by Lazaros Sakkas and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-20 with Medical categories.

Vasculitis, an inflammation of blood vessels, can be idiopathic or secondary to other conditions. Infections may also mimic idiopathic vasculitis, and the differential diagnosis is of paramount importance for the practicing physician. Vasculitides are not rare diseases. In fact, some vasculitides, such as giant cell arteritis, cutaneous vasculitis, and ANCA-associated vasculitis are relatively common in everyday practice. Vasculitis may rapidly lead to organ failure, and put patient's life in danger. Therefore, physicians of different specialties should diagnose vasculitis early, because early institution of treatment is crucial for the favorable outcome. In recent years progress has been made in the pathophysiology and treatment of vasculitis. This book reflects all new advances in pathogenetic mechanisms, diagnosis, and treatment of different types of vasculitis. The international panel of authors helps in achieving a balanced view on different aspects of vasculitis.

Essential Immunology For Surgeons

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Author : Oleg Eremin
language : en
Publisher: Oxford University Press, USA
Release Date : 2011-04-28

Essential Immunology For Surgeons written by Oleg Eremin and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-28 with Medical categories.

Providing the necessary foundation for a critical understanding of this rapidly expanding area of biological science that underpins and explains the modern concepts of a wide range of diseases and conditions, this book gives a concise, readable, and up-to-date account of immunology in general and its translation into key areas of clinical practice.

Toll Like Receptors Tlrs And Innate Immunity

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Author : Stefan Bauer
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-11

Toll Like Receptors Tlrs And Innate Immunity written by Stefan Bauer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-11 with Medical categories.

Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.

Heat Shock Proteins In Human Diseases

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Author : Alexzander A. A. Asea
language : en
Publisher: Springer Nature
Release Date : 2021-03-23

Heat Shock Proteins In Human Diseases written by Alexzander A. A. Asea and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-23 with Science categories.

The book Heat Shock Proteins in Cancer Therapeutics provides the most comprehensive review on contemporary knowledge on the role of HSP in various types of cancer therapeutics. Using an integrative approach, the contributors provide a synopsis of the most current updates on the state of HSP in cancer therapeutics. The heat shock response pathway is a highly conserved cellular process. Heat shock factors are a master transcriptional regulator responsible for expression of several important heat shock proteins, which can effectively protect critical client proteins from misfolding and degradation, thus maintaining intracellular integrity under stressed conditions. Recent studies have demonstrated the direct connections between heat shock response players and tumor cell survival, validating heat shock response players as novel molecular targets in anticancer treatment. Although many hurdles in clinical application still need to be effectively addressed, such as undesirable drug toxicity and off target effects; narrow therapeutic window; poor PK/PD profiles, etc. Recent reports on synergistic drug combination, advanced prodrug design, smart nanoparticle packaging, and RNA aptamer selection offer promising solutions to overcome these challenges. Future advancements in this fast-growing area can potentially lead to the next generation of cancer therapeutics. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

Aspirin Exacerbated Respiratory Disease An Issue Of Immunology And Allergy Clinics Of North America

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Author : Andrew A. White
language : en
Publisher: Elsevier Health Sciences
Release Date : 2016-10-07

Aspirin Exacerbated Respiratory Disease An Issue Of Immunology And Allergy Clinics Of North America written by Andrew A. White and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-07 with Medical categories.

This issue of Immunology and Allergy Clinics, guest edited by Dr. Andrew A. White, is devoted to Aspirin-Exacerbated Respiratory Disease. Articles in this issue include: An Overview of Non-Steroidal Anti-inflammatory Drug Reactions; The Clinical Presentation of Aspirin-Exacerbated Respiratory Disease; Diagnostic Evaluation in Aspirin-Exacerbated Respiratory Disease; Aspirin-Exacerbated Respiratory Disease as an Endotype of Chronic Rhinosinusitis; Pathogenesis of Aspirin Reactions in Aspirin-Exacerbated Respiratory Disease; Performing Aspirin Desensitization; Clinical Trials in Aspirin-Exacerbated Respiratory Disease Treatment; Eosinophils and Mast Cells in Aspirin-Exacerbated Respiratory Disease; Mechanisms of Benefit with Aspirin Therapy; Lipid Mediators in Aspirin-Exacerbated Respiratory Disease; and Epigenetic and Genetic Components of Aspirin-Exacerbated Respiratory Disease.

International Review Of Cytology

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Author :
language : en
Publisher: Elsevier
Release Date : 2002-09-11

International Review Of Cytology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-11 with Science categories.

International Review of Cytology presents current advances and comprehensive reviews in cell biology—both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Authored by some of the foremost scientists in the field Provides up-to-date information and directions for future research Valuable reference material for advanced undergraduates, graduate students and professional scientists

Neuroimmune Diseases

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Author : Hiroshi Mitoma
language : en
Publisher: Springer
Release Date : 2019-08-13

Neuroimmune Diseases written by Hiroshi Mitoma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-13 with Medical categories.

A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases