Hyperthermia And The Therapy Of Malignant Tumors
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Hyperthermia And The Therapy Of Malignant Tumors
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Author : Christian Streffer
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Hyperthermia And The Therapy Of Malignant Tumors written by Christian Streffer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Tumour therapy depends essentially on being able to destroy the clonogenic activity of tumour cells while keeping the damage to the normal tissue low. Clinical experience shows that tumour response varies greatly even if tumours with the same localisation, clinical, and histopathological staging are compared. Some tumours appear to be resistant to conventional radiotherapy (X-rays, y-rays or fast electrons) or chemotherapy. In these cases new therapy modalities are necessary. Combined therapy modalities seem to have advan tages for some resistant tumours; one possibility of such a treatment is to combine radiotherapy or chemotherapy with hyperthermia. This means that the local tumour, the tumour region or even the whole body of the patient has to be heated to temperatures between 40° to 45° C (in case of whole body hyperthermia to 42° C maximal) for a certain time (usually 30-60 min are adequate). Hyperthermia has a long tradition in medicine as a treatment modality for various diseases. Inscriptions of the old Egyptians and texts of the Greeks have pointed out its importance. Usually whole body hyperthermia has been used by the induction of fever. Local hyperthermia began around 1900 when Westermark treated unre sectable cervix carcinomas with hot water in a metallic coil. By the beginning of this century an increase of radiation effects was hy pothesised with hypothermia and later observed. However, only in the 1960s and 1970s were systematic investigations started which showed radiosensitisation and chemosensitisation by hyperthermia in cells and tissues including tumours.
Hyperthermia And The Therapy Of Malignant Tumors
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Author : Christian Streffer
language : en
Publisher: Springer
Release Date : 2012-01-06
Hyperthermia And The Therapy Of Malignant Tumors written by Christian Streffer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-06 with Medical categories.
Hyperthermia In Cancer Treatment A Primer
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Author : Gian F. Baronzio
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-05-08
Hyperthermia In Cancer Treatment A Primer written by Gian F. Baronzio and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-08 with Medical categories.
Following an introductory overview, Hyperthermia In Cancer Treatment: A Primer comprehensively describes the biological reasons for associating hyperthermia with radiation and chemotherapy and the biological and clinical effects of hyperthermia on cancerous and normal tissues. The volume’s 20 chapters are arranged in three principal parts: physical and methodological studies, biologic principles, and clinical studies.
Hyperthermia In Cancer Therapy
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Author : F. Kristian Storm
language : en
Publisher:
Release Date : 1983
Hyperthermia In Cancer Therapy written by F. Kristian Storm and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Medical categories.
Hyperthermia In Cancer Treatment
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Author : Leopold J. Anghileri
language : en
Publisher: CRC Press
Release Date : 2019-06-18
Hyperthermia In Cancer Treatment written by Leopold J. Anghileri and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-18 with Medical categories.
First published in 1986, Hyperthermia in Cancer Treatment is a most useful guide to the relationship between Hyperthermia, and the ways in which it is used for the control of cancer. Well-structured and comprehensive, this book is a must-read for any students of Oncology or professionals in their respective fields.
Thermoradiotherapy And Thermochemotherapy
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Author : M.Heinrich Seegenschmiedt
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Thermoradiotherapy And Thermochemotherapy written by M.Heinrich Seegenschmiedt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy, of ionising radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Problems remain with regard to maximizing the effects of hyperthermia as in fluenced by blood flow, heat loss, etc. The present volume defines the current knowledge relative to hyperthermia with radiation therapy and/or chemotherapy, giving a comprehensive overview of its use in cancer management. Philadelphia/Hamburg, June 1995 L.W. BRADY H.-P. HEILMANN Preface In an attempt to overcome tumor resistance, hypoxia, or unfavorable tumor condi tions, oncological research has come to focus on gene therapy, immunotherapy, new cytotoxic agents, and increasingly sophisticated radiotherapy. Radiation research has been directed towards heavy particle therapy and modification of the radiation response by either protecting or sensitizing agents. Improved dose localization using rotational or conformal strategies has also been implemented. Recently, changes in radiation fractionation schedules have shown promise of better results. Hyperthermia in cancer therapy can be viewed similarly as another means to increase the sensitivity of tumors to radio- and chemotherapy.
Hyperthermia In Oncology
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Author : Clifford L. K. Pang
language : en
Publisher: CRC Press
Release Date : 2015-05-26
Hyperthermia In Oncology written by Clifford L. K. Pang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-26 with Medical categories.
Hyperthermia in oncology is the application of heat to a patient's body for the purpose of cancer treatment. In recent years, its use has seen rapid development, with a large amount of clinical data becoming available. Hyperthermia in Oncology synthesizes the current research on the topic and provides treatment protocols for using localized as well
Biological Basis Of Oncologic Thermotherapy
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Author : Michel Gautherie
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Biological Basis Of Oncologic Thermotherapy written by Michel Gautherie and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Studies on the effects of hyperthermia have aroused great interest in recent years. On the one hand, it has been demonstrated. that hyperthermia may be a useful treatment modality for tumors, in combination with ionizing radia tion or cytotoxic drugs. On the other hand, it is of great scientific interest to study the effects of increased temperature on biological systems. Although hyperthermia has been used in the treatment of cancer for cen turies, its therapeutic success was doubtful. However, since it has been shown that radiation-induced cell killirtg can be remarkably enhanced by hyperthermia, many investigations have been performed with cells in vitro, tumors in situ, and normal tissues. From these studies it has been concluded that many biological phenomena and their characteristics which are found in tumors may be conducive to the use of hyperthermia in cancer therapy. Many researchers are studying the cell-killing mechanisms of heat and fac tors that modify cell thermosensitivity. A very fascinating biological phenomenon is the general observation that living cells can enhance their thermoresistance within hours of heat treatment. The development of such thermotolerance is apparently a universal process, and its mechanism is of general scientific interest. Metabolic and physiological processes are changed during and after hyperthermic treatment. These changes exert a strong feedback on the thermo sensitivity of cells and tissues, and also in fluence the heating characteristics of tissues, especially in tumors.
Hyperthermia
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Author : Haim I. Bicher
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Hyperthermia written by Haim I. Bicher and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
Consensus On Hyperthermia For The 1990s
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Author : Haim I. Bicher
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-08
Consensus On Hyperthermia For The 1990s written by Haim I. Bicher and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Medical categories.
Hyperthermia as a safe and effective cancer treatment modality is rapidly evolving propelled by widespread research and clinical efforts worldwide. Presentations on Hyperthermia experience are now commonplace at Oncology meetings, as are congresses dedicated entirely to the intertwined interactions between basic sciences and patient treatment that together are forming the structure of a new medical specialty. Such was the XII International Symposium on Clinical Hyperthermia held in Rome, Italy, April 27 - 29, 1989. Papers presented therein constitute the backbone of this book. Biology research has provided data describing mechanisms of action for the cancer cell killing and physiological effects of Hyperthermia. Physics research has led to the development of equipment enabling treatment of many areas of the human body, as well as explained the limitations that still constrain our ability to treat, especially in the areas of deep seated tumor heating and non-invasive thermometry. The main question that will decide the future of this modality is that of its clinical use. To put it succinctly, what do we do with this potentially useful tool in an everyday clinical oncological practice . •• ? This is the main question addressed in this book as "Consensus on Hyperthermia for the 1990s. " The book in cludes 28 presented papers and 25 invited chapters from some of the leading experts in the field. Their basic mechanisms of action were physics principles, treatment quality assurance and especially, clinical indications.