I Association Behavior Of Achc Rich Ss Peptide Foldamers

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I Association Behavior Of Achc Rich Ss Peptide Foldamers

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Author : William Charles Pomerantz
language : en
Publisher:
Release Date : 2008

I Association Behavior Of Achc Rich Ss Peptide Foldamers written by William Charles Pomerantz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.

Supramolecular Chemistry In Water

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Author : Stefan Kubik
language : en
Publisher: John Wiley & Sons
Release Date : 2019-09-03

Supramolecular Chemistry In Water written by Stefan Kubik and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-03 with Science categories.

Provides deep insight into the concepts and recent developments in the area of supramolecular chemistry in water Written by experts in their respective field, this comprehensive reference covers various aspects of supramolecular chemistry in water?from fundamental aspects to applications. It provides readers with a basic introduction to the current understanding of the properties of water and how they influence molecular recognition, and examines the different receptor types available in water and the types of substrates that can be bound. It also looks at areas to where they can be applied, such as materials, optical sensing, medicinal imaging, and catalysis. Supramolecular Chemistry in Water offers five major sections that address important topics like water properties, molecular recognition, association and aggregation phenomena, optical detection and imaging, and supramolecular catalysis. It covers chemistry and physical chemistry of water; water-mediated molecular recognition; peptide and protein receptors; nucleotide receptors; carbohydrate receptors; and ion receptors. The book also teaches readers all about coordination compounds; self-assembled polymers and gels; foldamers; vesicles and micelles; and surface-modified nanoparticles. In addition, it provides in-depth information on indicators and optical probes, as well as probes for medical imaging. -Covers, in a timely manner, an emerging area in chemistry that is growing more important every day -Addresses topics such as molecular recognition, aggregation, catalysis, and more -Offers comprehensive coverage of everything from fundamental aspects of supramolecular chemistry in water to its applications -Edited by one of the leading international scientists in the field Supramolecular Chemistry in Water is a one-stop-resource for all polymer chemists, catalytic chemists, biochemists, water chemists, and physical chemists involved in this growing area of research.

Foldamers

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Author : Stefan Hecht
language : en
Publisher: John Wiley & Sons
Release Date : 2007-09-24

Foldamers written by Stefan Hecht and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-24 with Science categories.

This truly comprehensive treatise of foldamers, from synthesis to applications in bio-, material-, and nanoscience is at once an introduction to the topic, while providing in-depth accounts on various aspects clearly aimed at the specialist. The book is clearly structured, with the first part concentrating on structure and foldamer design concepts, while the second part covers functional aspects from properties to applications. The international team of expert authors provides overviews of synthetic approaches as well as analytical techniques.

Peptides And Peptide Based Biomaterials And Their Biomedical Applications

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Author : Anwar Sunna
language : en
Publisher: Springer
Release Date : 2017-10-26

Peptides And Peptide Based Biomaterials And Their Biomedical Applications written by Anwar Sunna and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-26 with Science categories.

Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as β-sheet fibril-forming peptides and α-helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.

Liquid Crystals

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Author : Pankaj Kumar Choudhury
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-02-28

Liquid Crystals written by Pankaj Kumar Choudhury and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-28 with Science categories.

Liquid crystals exhibit amazingly interesting properties that make them indispensable for several technological applications. The book Liquid Crystals - Recent Advancements in Fundamental and Device Technologies is aimed to focus on various aspects of research and development that liquid crystal mediums have come across in recent years. This would be ranging from the physical and chemical properties to the important applications that the liquid crystals have in our everyday life. It is expected that the book will make the expert researchers to be abreast of recent research advancements, whereas the novice researchers will benefit from both the conceptual understanding and the recent developments in the area. Multitudes of research themes and directions pivoted to liquid crystals remain the essence, which the readers would get the glimpse of and move ahead for further investigations.

Peptide Libraries

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Author : Ratmir Derda
language : en
Publisher: Humana
Release Date : 2016-09-24

Peptide Libraries written by Ratmir Derda and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-24 with Science categories.

This volume provides an overview of modern and emerging methods for production, analysis, and utility of peptide libraries. Chapter focus on methods and techniques for synthesis, genetic expression, hybrid synthesis-expression, examples of modern utility of these libraries, de novo discovery of reactions, hybrid organic-inorganic materials and, emerging tools for the analysis of these libraries by method of genetic selection and next-generation sequencing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Peptide Libraries: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies.

Peptaibiotics

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Author : Claudio Toniolo
language : en
Publisher: John Wiley & Sons
Release Date : 2009-05-26

Peptaibiotics written by Claudio Toniolo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-26 with Science categories.

Originally a special issue of Chemistry & Biodiversity, this is an excellent overview of the status of contemporary studies in peptaibiotics, covering aspects ranging from the search for novel bioactive compounds to considerations of their membrane-modifying properties.

Lasso Peptides

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Author : Yanyan Li
language : en
Publisher: Springer
Release Date : 2014-10-21

Lasso Peptides written by Yanyan Li and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-21 with Medical categories.

Lasso peptides form a growing family of fascinating ribosomally-synthesized and post-translationally modified peptides produced by bacteria. They contain 15 to 24 residues and share a unique interlocked topology that involves an N-terminal 7 to 9-residue macrolactam ring where the C-terminal tail is threaded and irreversibly trapped. The ring results from the condensation of the N-terminal amino group with a side-chain carboxylate of a glutamate at position 8 or 9, or an aspartate at position 7, 8 or 9. The trapping of the tail involves bulky amino acids located in the tail below and above the ring and/or disulfide bridges connecting the ring and the tail. Lasso peptides are subdivided into three subtypes depending on the absence (class II) or presence of one (class III) or two (class I) disulfide bridges. The lasso topology results in highly compact structures that give to lasso peptides an extraordinary stability towards both protease degradation and denaturing conditions. Lasso peptides are generally receptor antagonists, enzyme inhibitors and/or antibacterial or antiviral (anti-HIV) agents. The lasso scaffold and the associated biological activities shown by lasso peptides on different key targets make them promising molecules with high therapeutic potential. Their application in drug design has been exemplified by the development of an integrin antagonist based on a lasso peptide scaffold. The biosynthesis machinery of lasso peptides is therefore of high biotechnological interest, especially since such highly compact and stable structures have to date revealed inaccessible by peptide synthesis. Lasso peptides are produced from a linear precursor LasA, which undergoes a maturation process involving several steps, in particular cleavage of the leader peptide and cyclization. The post-translational modifications are ensured by a dedicated enzymatic machinery, which is composed of an ATP-dependent cysteine protease (LasB) and a lactam synthetase (LasC) that form an enzymatic complex called lasso synthetase. Microcin J25, produced by Escherichia coli AY25, is the archetype of lasso peptides and the most extensively studied. To date only around forty lasso peptides have been isolated, but genome mining approaches have revealed that they are widely distributed among Proteobacteria and Actinobacteria, particularly in Streptomyces, making available a rich resource of novel lasso peptides and enzyme machineries towards lasso topologies.

G Protein Coupled Receptors

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Author : Jesus Giraldo
language : en
Publisher: Royal Society of Chemistry
Release Date : 2011-08-16

G Protein Coupled Receptors written by Jesus Giraldo and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-16 with Science categories.

G protein-coupled receptors (GPCRs) are the largest family of cell-surface receptors, with more than 800 members identified thus far in the human genome. They regulate the function of most cells in the body, and represent approximately 3% of the genes in the human genome. These receptors respond to a wide variety of structurally diverse ligands, ranging from small molecules, such as biogenic amines, nucleotides and ions, to lipids, peptides, proteins, and even light. Ligands (agonists and antagonists) acting on GPCRs are important in the treatment of numerous diseases, including cardiovascular and mental disorders, retinal degeneration, cancer, and AIDS. It is estimated that these receptors represent about one third of the actual identified targets of clinically used drugs. The determination of rhodopsin crystal structure and, more recently, of opsin, 1 and 2 adrenergic and A2A adenosine receptors provides both academia and industry with extremely valuable data for a better understanding of the molecular determinants of receptor function and a more reliable rationale for drug design. GPCR structure and function constitutes a hot topic. The book, which lies between the fields of chemical biology, molecular pharmacology and medicinal chemistry, is divided into three parts. The first part considers what receptor structures tell us about the mechanism of receptor activation. Part II focuses on receptor function. It discusses what the data from biophysical and mutational studies, and the analysis of the interactions of the receptor with ligands and regulator proteins, tell us about the process of signal transduction. The final part, on modelling and simulation, details new insights on the link between structure and mechanism and their implications in drug design.

Macromolecules At Interfaces

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Author : Jaroslav Kahovec
language : en
Publisher: Wiley-VCH
Release Date : 1999-09-16

Macromolecules At Interfaces written by Jaroslav Kahovec and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-09-16 with Science categories.

This book contains selected contributions of the symposium "Surface and Interfacial Phenomena in Macromolecular Systens", 17th Discussion Conference of the Prague Meeting on Macromolecules, presenting developments and concepts in the field of surface and interfacial phenomena in macromolecular systems. The emphasis was put on the behaviour of polymer chains in surface and interfacial layers, the methods of studying these layers in polymer systems, and influence of interfacial phenomena on the properties of multiphase polymer blends.