Identification Of Peptidases In Highly Pathogenic Versus Weakly Pathogenic Naegleria Fowleri Amebae
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Identification Of Peptidases In Highly Pathogenic Versus Weakly Pathogenic Naegleria Fowleri Amebae
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Author : Ishan Kaushikkumar Vyas
language : en
Publisher:
Release Date : 2014
Identification Of Peptidases In Highly Pathogenic Versus Weakly Pathogenic Naegleria Fowleri Amebae written by Ishan Kaushikkumar Vyas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Naegleria fowleri, a free-living ameba, is the causative agent of Primary Amebic Meningoencephalitis. Highly-pathogenic mouse-passaged amebae (Mp) and weakly-pathogenic axenically-grown (Ax) N. fowleri were examined for peptidase activity. Zymography and azocasein peptidase activity assays demonstrated that Mp and Ax N. fowleri exhibited a similar peptidase pattern. Prominent for whole cell lysates, membranes and conditioned medium from Mp and Ax amebae were the presence of an activity band of approximately 58kDa and 100 kDa bands susceptible to the action of cysteine and metallopeptidase inhibitors, respectively. Further roles of the peptidases during the invasion process were examined by in vitro invasion assays in the presence of inhibitors and Cysteine and metallopeptidase inhibitors were found to greatly reduce invasion through the ECM. This study establishes a functional linkage of the expressed peptidases to the invasion process, and these peptidases may serve as a candidate target for therapeutic management of N. fowleri infection.
Paniker S Textbook Of Medical Parasitology
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Author : C. K. Jayaram Paniker
language : en
Publisher: JP Medical Ltd
Release Date : 2017-09-14
Paniker S Textbook Of Medical Parasitology written by C. K. Jayaram Paniker and has been published by JP Medical Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-14 with Medical categories.
The new edition of this textbook is a complete guide to parasitology for undergraduate medical students. Divided into 23 chapters, each topic has been thoroughly updated and expanded to cover the most recent advances and latest knowledge in the field. The book begins with an overview of parasitology, then discusses numerous different types of parasite, concluding with a chapter on diagnosis methods. Many chapters have been rewritten and the eighth edition of the book features many new tables, flow charts and photographs. Each chapter concludes with a ‘key points’ box to assist with revision. Key points Eighth edition providing undergraduates with a complete guide to parasitology Fully revised text with many new topics, tables and photographs Each chapter concludes with ‘key points’ box to assist revision Previous edition (9789350905340) published in 2013
Bad Bug Book
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Author : Mark Walderhaug
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2014-01-14
Bad Bug Book written by Mark Walderhaug and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-14 with Medical categories.
The Bad Bug Book 2nd Edition, released in 2012, provides current information about the major known agents that cause foodborne illness.Each chapter in this book is about a pathogen—a bacterium, virus, or parasite—or a natural toxin that can contaminate food and cause illness. The book contains scientific and technical information about the major pathogens that cause these kinds of illnesses.A separate “consumer box” in each chapter provides non-technical information, in everyday language. The boxes describe plainly what can make you sick and, more important, how to prevent it.The information provided in this handbook is abbreviated and general in nature, and is intended for practical use. It is not intended to be a comprehensive scientific or clinical reference.The Bad Bug Book is published by the Center for Food Safety and Applied Nutrition (CFSAN) of the Food and Drug Administration (FDA), U.S. Department of Health and Human Services.
Eukaryome Impact On Human Intestine Homeostasis And Mucosal Immunology
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Author : Nancy Guillen
language : en
Publisher: Springer Nature
Release Date : 2020-06-01
Eukaryome Impact On Human Intestine Homeostasis And Mucosal Immunology written by Nancy Guillen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-01 with Medical categories.
Multiple demographic or economic parameters contribute to the origin of emerging infections, for example: poverty, urbanization, climate change, conflicts and population migrations. All these factors are a challenge to assess the impact (present and future) of parasitic diseases on public health. The intestine is a major target of these infections; it is a nutrient-rich environment harbouring a complex and dynamic population of 100 trillion microbes: the microbiome. Most researches on the microbiome focus on bacteria, which share the gut ecosystem with a population of uni- and multi cellular eukaryotic organisms that may prey on them. Our interest focuses on the families of eukaryotic microbes inhabiting the intestine, called “intestinal eukaryome”, that include fungi, protists and helminths. Knowledge on the reciprocal influence between the microbiome and the eukaryome, and on their combined impact on homeostasis and intestinal diseases is scanty and can be considered as an important emerging field. Furthermore, the factors that differentiate pathogenic eukaryotes from commensals are still unknown. This book presents an overview of the science presented and discussed in the First Eukaryome Congress held from October 16th to 18th, 2019 at the Pasteur Institute in Paris. This book covers the following topics: Phylogenetic, prevalence, and diversity of intestinal eukaryotic microbes; and their (still enigmatic) historical evolution and potential contributions to mucosal immune homeostasis. Integrative biology to study the molecular cell biology of parasite-host interactions and the multiple parameters underlining the infectious process. The exploitation of tissue engineering and microfluidics to establish three-dimensional (3D) systems that help to understand homeostasis and pathological processes in the human intestine.
Meningitis And Encephalitis
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Author : Rodrigo Hasbun
language : en
Publisher: Springer
Release Date : 2018-07-19
Meningitis And Encephalitis written by Rodrigo Hasbun and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-19 with Medical categories.
Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae. The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs, overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportion of unknown etiologies, low sensitivity of current microbiological techniques especially in the setting of previous antibiotic therapy, underutilization of available molecular diagnostic tests, and empiric antibiotic therapy and hospitalization for viral meningitis cases. Even though there are published guidelines, compliance with them is not optimal and physicians do not follow standardized algorithms in their empirical approach. As meningitis and encephalitis is associated with high rates of adverse clinical outcomes, prevention, when feasible is of upmost importance. Adherence to protocols to prevent health-care associated meningitis and ventriculitis are effective but compliance with them is not uniformly performed. This book seeks to improve outcomes for meningitis and encephalitis cases handled by physicians who may or may not be thoroughly trained for these challenges. The text introduces the current guidelines but also discusses the gaps that leave clinicians struggling to implement the most appropriate approaches for these particular neurological infections. Each chapter delivers the tools necessary to identify and adhere to the most appropriate diagnostic technique, management protocols, and prevention approach for each situation. All chapters conclude with discourse on future directions in research and quality improvement. Written by experts in infectious diseases, the book covers topics that are the most devastating, including healthcare-acquired infections, autoimmune encephalitis, and infections as they present in HIV patients. Meningitis and Encephalitis is a well-rounded resource for all medical professionals encountering these neurological syndromes, including infectious disease specialists, neurologists, primary care physicians, and immunologists.
District Laboratory Practice In Tropical Countries Part 2
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Author : Monica Cheesbrough
language : en
Publisher: Cambridge University Press
Release Date : 2006-03-02
District Laboratory Practice In Tropical Countries Part 2 written by Monica Cheesbrough and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-02 with Medical categories.
This new edition includes an update on HIV disease/AIDS, recently developed HIV rapid tests to diagnose HIV infection and screen donor blood, and current information on antiretroviral drugs and the laboratory monitoring of antiretroviral therapy. Information on the epidemiology and laboratory investigation of other pathogens has also been brought up to date. Several new, rapid, simple to perform immunochromatographic tests to assist in the diagnosis of infectious diseases are described, including those for brucellosis, cholera, dengue, leptospirosis, syphilis and hepatitis. Recently developed lgM antibody tests to investigate typhoid fever are also described. The new classification of salmonellae has been introduced. Details of manufacturers and suppliers now include website information and e-mail addresses. The haematology and blood transfusion chapters have been updated, including a review of haemoglobin measurement methods in consideration of the high prevalence of anaemia in developing countries.
Parasitology
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Author : Alan Gunn
language : en
Publisher: John Wiley & Sons
Release Date : 2012-04-30
Parasitology written by Alan Gunn and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-30 with Medical categories.
Parasitology: An Integrated Approach, provides a concise, student-friendly account of parasites and parasite relationships that is supported by case studies and suggestions for student projects. The book focuses strongly on parasite interactions with other pathogens and in particular parasite-HIV interactions, as well as looking at how host behaviour contributes to the spread of infections. There is a consideration of the positive aspects of parasite infections, how humans have used parasites for their own advantage and also how parasite infections affect the welfare of captive and domestic animals. The emphasis of Parasitology is on recent research throughout and each chapter ends with a brief discussion of future developments. This text is not simply an updated version of typical parastitology books but takes an integrated approach and explains how the study of parasites requires an understanding of a wide range of other topics from molecular biology and immunology to the interactions of parasites with both their hosts and other pathogens.
Cambridge Scientific Biochemistry Abstracts
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Author :
language : en
Publisher:
Release Date : 1993
Cambridge Scientific Biochemistry Abstracts written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Amino acids categories.
The Bad Bug Book
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Author : FDA
language : en
Publisher: Imp
Release Date : 2004
The Bad Bug Book written by FDA and has been published by Imp this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
The Bad Bug was created from the materials assembled at the FDA website of the same name. This handbook provides basic facts regarding foodborne pathogenic microorganisms and natural toxins. It brings together in one place information from the Food & Drug Administration, the Centers for Disease Control & Prevention, the USDA Food Safety Inspection Service, and the National Institutes of Health.
Hugo And Russell S Pharmaceutical Microbiology
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Author : Stephen P. Denyer
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
Hugo And Russell S Pharmaceutical Microbiology written by Stephen P. Denyer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.
Completely revised and updated Pharmaceutical Microbiologycontinues to provide the essential resource for the 21st centurypharmaceutical microbiologist "....a valuable resource for junior pharmacists graspingan appreciation of microbiology, microbiologists entering thepharmaceutical field, and undergraduate pharmacy students." Journal of Antimicrobial Chemotherapy ".....highly readable. The content is comprehensive, withwell-produced tables, diagrams and photographs, and is accessiblethrough the extensive index." Journal of Medical Microbiology WHY BUY THIS BOOK? Completely revised and updated to reflect the rapid pace ofchange in the teaching and practice of pharmaceuticalmicrobiology Expanded coverage of modern biotechnology, including genomicsand recombinant DNA technology Updated information on newer antimicrobial agents and theirmode of action Highly illustrated with structural formulas of organiccompounds and flow diagrams of biochemical processes