Imaging The Microcirculation With High Frequency Ultrasound
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Imaging The Microcirculation With High Frequency Ultrasound Microform
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Author : David Eric Goertz
language : en
Publisher: National Library of Canada = Bibliothèque nationale du Canada
Release Date : 2002
Imaging The Microcirculation With High Frequency Ultrasound Microform written by David Eric Goertz and has been published by National Library of Canada = Bibliothèque nationale du Canada this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
Imaging The Microcirculation With High Frequency Ultrasound
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Author : Dustin E. Kruse
language : en
Publisher:
Release Date : 2004
Imaging The Microcirculation With High Frequency Ultrasound written by Dustin E. Kruse and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.
Detecting Measuring And Imaging The Microcirculation With High Frequency Doppler Ultrasound
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Author : Donald Allan Christopher
language : en
Publisher:
Release Date : 1998
Detecting Measuring And Imaging The Microcirculation With High Frequency Doppler Ultrasound written by Donald Allan Christopher and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.
The microcirculation plays varied and critical roles in our general well being and defects in the microcirculation manifest themselves in many important disease states. In this thesis, the extension of Doppler ultrasound to the ultrasound frequency range 20-200 MHz is investigated as a non-invasive and quantitative technique for detecting, measuring, and imaging the microcirculation. The theoretical advantages and limitations of high-frequency Doppler ultrasound (HFD) are discussed. Experimental continuous-wave and pulsed-wave HFD systems, which have been designed, constructed and optimised for detecting blood flow in the microcirculation, are described. Implementation of the systems at 40-MHz and 50-MHz in experimental investigations with phantoms show that HFD can detect and measure velocities on the order of the blood velocities found in the capillaries (
Detecting Measuring And Imaging The Microcirculation With High Frequency Doppler Ultrasound
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Author :
language : en
Publisher:
Release Date : 1998
Detecting Measuring And Imaging The Microcirculation With High Frequency Doppler Ultrasound written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.
Detecting Measuring And Imaging The Microcirculation With High Frequency Doppler Ultrasound Microform
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Author : Donald Allan Christopher
language : en
Publisher: National Library of Canada = Bibliothèque nationale du Canada
Release Date : 1998
Detecting Measuring And Imaging The Microcirculation With High Frequency Doppler Ultrasound Microform written by Donald Allan Christopher and has been published by National Library of Canada = Bibliothèque nationale du Canada this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.
Contrast Enhanced High Frequency Ultrasound Imaging Of Mice
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Author : Shawn Stapleton
language : en
Publisher:
Release Date : 2007
Contrast Enhanced High Frequency Ultrasound Imaging Of Mice written by Shawn Stapleton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Microbubble ultrasound contrast agents have shown clinical potential for characterising blood flow in the microcirculation using 1 to 10 MHz ultrasound; however, scaling their use for mouse imaging with high frequency ultrasound (10 to 60 MHz) has not been addressed. The goal was to determine the utility of microbubbles for contrast flow studies in the mouse with 30 MHz ultrasound by investigating their acoustic response in vitro and optimal dose in vivo. In vitro results showed that microbubble attenuation and backscatter increased linearly for concentrations between 2.4 x 106 and 2.8 x 107 bubbles per mL. In vivo results showed that the peak enhancement of the agent increased linearly for doses between 10 and 60 muL kg -1, the duration of enhancement varied between 200 to 300 seconds and the integrated enhancement (area under the curve) increased linearly up to 100 muL kg-1. These doses corresponded to the range of concentrations used in vitro. However, optimisation of the reproducibility of this technique still needs to be addressed.
Quantifying The Effects Of Radiation On Tumour Vasculature With High Frequency Three Dimensional Power Doppler Ultrasound
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Author : Clinton Hupple
language : en
Publisher:
Release Date : 2010
Quantifying The Effects Of Radiation On Tumour Vasculature With High Frequency Three Dimensional Power Doppler Ultrasound written by Clinton Hupple and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
Recent evidence suggests that radiation may have a significant effect on tumour vasculature in addition to damaging tumour cell DNA. It is well established that endothelial cells are among the first cells to respond after administration of ionizing radiation in both normal and tumour tissues. It has also been suggested that microvascular dysfunction may regulate tumour response to radiotherapy at high doses. However, due to limitations in imaging the microcirculation this response is not well characterized.Advances in high-frequency ultrasound and computation methods now make it possible to acquire and analyze 3-D ultrasound data of tumour blood flow in tumour microcirculation.This thesis outlines the work done to test the hypothesis that single dose 8 Gy radiotherapy produces changes in tumour blood vessels which can be quantified using high-frequency power Doppler ultrasound. In addition, the issue of reproducibility of power Doppler measurements and the relationship between histopathology and power Doppler measurements have been examined.
Apply High Frequency Ultrasound To Microcirculation Assessment In Small Animals
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Author : 陳佳君
language : en
Publisher:
Release Date : 2008
Apply High Frequency Ultrasound To Microcirculation Assessment In Small Animals written by 陳佳君 and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Microcirculation Imaging
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Author : Martin J. Leahy
language : en
Publisher: John Wiley & Sons
Release Date : 2012-05-22
Microcirculation Imaging written by Martin J. Leahy and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-22 with Medical categories.
Adopting a multidisciplinary approach with input from physicists, researchers and medical professionals, this is the first book to introduce many different technical approaches for the visualization of microcirculation, including laser Doppler and laser speckle, optical coherence tomography and photo-acoustic tomography. It covers everything from basic research to medical applications, providing the technical details while also outlining the respective strengths and weaknesses of each imaging technique. Edited by an international team of top experts, this is the ultimate handbook for every clinician and researcher relying on microcirculation imaging.
Handbook Of In Vivo Chemistry In Mice
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Author : Katsunori Tanaka
language : en
Publisher: John Wiley & Sons
Release Date : 2020-04-27
Handbook Of In Vivo Chemistry In Mice written by Katsunori Tanaka and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-27 with Science categories.
Provides timely, comprehensive coverage of in vivo chemical reactions within live animals This handbook summarizes the interdisciplinary expertise of both chemists and biologists performing in vivo chemical reactions within live animals. By comparing and contrasting currently available chemical and biological techniques, it serves not just as a collection of the pioneering work done in animal-based studies, but also as a technical guide to help readers decide which tools are suitable and best for their experimental needs. The Handbook of In Vivo Chemistry in Mice: From Lab to Living System introduces readers to general information about live animal experiments and detection methods commonly used for these animal models. It focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release. Topics include: currently available mouse models; biocompatible fluorophores; radionuclides for radiodiagnosis/radiotherapy; live animal imaging techniques such as positron emission tomography (PET) imaging; magnetic resonance imaging (MRI); ultrasound imaging; hybrid imaging; biocompatible chemical reactions; ligand-directed nucleophilic substitution chemistry; biorthogonal prodrug release strategies; and various selective targeting strategies for live animals. -Completely covers current techniques of in vivo chemistry performed in live animals -Describes general information about commonly used live animal experiments and detection methods -Focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release -Places emphasis on material properties required for the development of appropriate compounds to be used for imaging and therapeutic purposes in preclinical applications Handbook of In Vivo Chemistry in Mice: From Lab to Living System will be of great interest to pharmaceutical chemists, life scientists, and organic chemists. It will also appeal to those working in the pharmaceutical and biotechnology industries.