Immunodiagnostics
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Immunodiagnostics
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Author : R. Edwards
language : en
Publisher: OUP Oxford
Release Date : 1999-11-25
Immunodiagnostics written by R. Edwards and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-11-25 with Science categories.
Immunodiagnostic tests are analytical methods that use antibodies as reagents whose results are used to aid diagnosis and are widely used in many scientific disciplines and in many different ways. Perhaps the most widespread and obvious use is in clinical applications, but immunodiagnostic tests are also used in other fields such as forensic science and environmental and food analysis. The different types of test range from simple manual methods to fully automated systems with sophisticated integrated detection. Immunodiagnostics: A Practical Approach starts off by explaining the principles and development of immunodiagnostic tests, specifically the use of radioisotopes as tracers. Chapter 2 explains the use of solid-phase supports to bind immunoreagents. Enzymes are widely used as labels in immunoassays and their use with colourimetric, fluorimetric, and chemiluminescent detection systems is described. The use of enzymes as labels reflects the move away from radioisotopes and one of the most powerful non- radioisotpoc prodcedures is the time-resolved fluorescence assay. Enzymes can also be used as a simple method of obtaining high performance from immunodiagnostics and this application is covered later in the book. The next set of techniques to be described are light scattering techniques, which can be used in either simple manual assays or in sophisticated automated procedures. The penultimate chapter describes the principles of automation of immunodiagnostic tests. The last topic to be discussed is that of quality assurance.
Principles Of Immunology And Immunodiagnostics
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Author : Ralph Michael Aloisi
language : en
Publisher:
Release Date : 1988
Principles Of Immunology And Immunodiagnostics written by Ralph Michael Aloisi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.
Immunodiagnostic Technologies From Laboratory To Point Of Care Testing
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Author : Pankaj Suman
language : en
Publisher: Springer Nature
Release Date : 2020-10-12
Immunodiagnostic Technologies From Laboratory To Point Of Care Testing written by Pankaj Suman and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-12 with Medical categories.
This book presents the timeline of immunodiagnostics evolution, including advancements in immunological/nucleic acid probes, assay design, labelling techniques, and devices for signal transduction and acquisition. In the past few years, enzyme and nanocatalyst-based immune assays have undergone numerous modifications to enhance their sensitivity and potential for automation. Further, to reduce production costs and the use of laboratory animals, engineering small antibodies and nucleic acid probes (aptamers) has become increasingly popular in the development of novel and powerful bioassays. In light of the notable advancements in immunodiagnostics, this book highlights the combined efforts of clinicians, biotechnologists, material scientists, nanotechnologists and basic scientists in a coherent and highly structured way. The book takes readers on the journey of immunodiagnostic technologies, from their introduction to the present.
Clinical Immunodiagnostics Laboratory Principles And Practices
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Author : Ian C. Clift
language : en
Publisher: Jones & Bartlett Learning
Release Date : 2020-02-07
Clinical Immunodiagnostics Laboratory Principles And Practices written by Ian C. Clift and has been published by Jones & Bartlett Learning this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-07 with Medical categories.
A contemporary guide to the diagnostic principles and practices of immunology and serology in the clinical laboratory.
Immunodiagnostics And Patient Safety
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Author : Krystyna Sztefko
language : en
Publisher: Walter de Gruyter
Release Date : 2011-05-26
Immunodiagnostics And Patient Safety written by Krystyna Sztefko and has been published by Walter de Gruyter this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-26 with Medical categories.
Today most of immunochemistry methods for the determination of proteins, peptides, drugs, and many small molecules are fully automated, with good precision, excellent sensitivity and short reaction time. However, inaccuracy due to poor standardization and the presence of interfering substances in biological samples is still a serious and life-threatening issue. Proper validation of methods and quality assurance have little effect on frequency of occurrence of false positive or false negative results, which, if unrecognized, may lead to patient's misdiagnosis, unnecessary treatment or even unnecessary surgery. Deep knowledge of basic principles of immunochemical methods (antigen-antibody reaction, standardization, matrix effect, limit of detection, cross-reactivity, etc.), sources of analyte-independent interferences (preanalitycal errors, the presence of binding proteins, the presence of autoantibodies) and analyte-dependent interferences (presence of heterophilic antibodies, high-dose effect) are very important to understand, detect, reduce and/or eliminate the interferences. This book helps to reduce false results and, at the same time, improve patient's care and patient's safety.
Principles Of Immunodiagnostics
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Author : Ralph Michael Aloisi
language : en
Publisher:
Release Date : 1979-01-01
Principles Of Immunodiagnostics written by Ralph Michael Aloisi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979-01-01 with Immunodiagnosis categories.
Breast Cancer Immunodiagnosis And Immunotherapy
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Author : Roberto Ceriani
language : en
Publisher: Springer
Release Date : 2013-04-17
Breast Cancer Immunodiagnosis And Immunotherapy written by Roberto Ceriani and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.
The convening of the 3rd International Workshop on Monoclonal Antibodies and Breast Cancer had the character of a self-search exercise. After almost a decade of research in the basic and applied aspects of the use of serological means to diagnose and possibly treat breast cancer several milestones have been reached. Among them a clear understanding of immunopathological use and limitations of monoclonal antibodies against breast epithelium, the complete development and clinical use of immunoassays for circulating breast epithelial antigens, the striking advances in the diagnostic use of monoclonal antibodies to estrogen and progesterone receptor proteins and the first communications on proposed immunotherapeutic use of different conjugates of anti-breast antibodies. New areas of investigation have developed in our field, some which are reaching a full blossom while others are still facing obstacles and at times a re-definition of their goals and objectives. These meetings have acted in a way as a clearing house and have permitted their attendees to derive predictions that have helped shape future research and fine-tune objectives. But above all, the re-evaluation of past research at these Workshops and the renewed excitement brought to them by new information has helped generate a momentum and enthusiasm that assures for the future large scientific gains.
Immunodiagnostics
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Author :
language : en
Publisher:
Release Date : 1991-09-01
Immunodiagnostics written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-09-01 with categories.
Principles Of Immunology And Immunodiagnostics
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Author : Ralph M. Aloisi
language : en
Publisher:
Release Date :
Principles Of Immunology And Immunodiagnostics written by Ralph M. Aloisi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
The Immunoassay Handbook
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Author : David Wild
language : en
Publisher: Newnes
Release Date : 2013-01-21
The Immunoassay Handbook written by David Wild and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-21 with Science categories.
The fourth edition of The Immunoassay Handbook provides an excellent, thoroughly updated guide to the science, technology and applications of ELISA and other immunoassays, including a wealth of practical advice. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary practice and in pharmaceutical and life science research. Highly illustrated and clearly written, this award-winning reference work provides an excellent guide to this fast-growing field. Revised and extensively updated, with over 30% new material and 77 chapters, it reveals the underlying common principles and simplifies an abundance of innovation. The Immunoassay Handbook reviews a wide range of topics, now including lateral flow, microsphere multiplex assays, immunohistochemistry, practical ELISA development, assay interferences, pharmaceutical applications, qualitative immunoassays, antibody detection and lab-on-a-chip. This handbook is a must-read for all who use immunoassay as a tool, including clinicians, clinical and veterinary chemists, biochemists, food technologists, environmental scientists, and students and researchers in medicine, immunology and proteomics. It is an essential reference for the immunoassay industry. Provides an excellent revised guide to this commercially highly successful technology in diagnostics and research, from consumer home pregnancy kits to AIDS testing.www.immunoassayhandbook.com is a great resource that we put a lot of effort into. The content is designed to encourage purchases of single chapters or the entire book. David Wild is a healthcare industry veteran, with experience in biotechnology, pharmaceuticals, medical devices and immunodiagnostics, which remains his passion. He worked for Amersham, Eastman-Kodak, Johnson & Johnson, and Bristol-Myers Squibb, and consulted for diagnostics and biotechnology companies. He led research and development programs, design and construction of chemical and biotechnology plants, and integration of acquired companies. Director-level positions included Research and Development, Design Engineering, Operations and Strategy, for billion dollar businesses. He retired from full-time work in 2012 to focus on his role as Editor of The Immunoassay Handbook, and advises on product development, manufacturing and marketing. Provides a unique mix of theory, practical advice and applications, with numerous examples Offers explanations of technologies under development and practical insider tips that are sometimes omitted from scientific papers Includes a comprehensive troubleshooting guide, useful for solving problems and improving assay performancee Provides valuable chapter updates, now available on www.immunoassayhandbook.com