Immunologic Aspects Of Testicular Function
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Immunologic Aspects Of Testicular Function
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Author : R.E. Mancini
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immunologic Aspects Of Testicular Function written by R.E. Mancini and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
It has become increasingly evident within the last few decades that immunologic factors are involved in some aspects of the reproductive process and hence in the physiology and pathology of the genital tract. The concept that immune phenomena participate in human reproduction is not new. There are examples throughout the history of man that immune phenomena may have influenced the reproductive process. For example, the Bible states that Sarah was sterile for a long time but conceived in the later years of her marriage. This could be interpreted to mean that continued exposure to her husband's ejaculated antigens re sulted in antibody response, sufficient to induce sterility. However, after continence of long duration, the antibody level declined and conception became possible. Another of speculation is Darwin's Descent of Man, which contains a number of state source ments to the effect that profligacy of women may account for their "small fertility". The inference is that repeated exposure to antigenic material in the ejaculate causes antibody responses that lead to infertility (KATSH and KATSH, 1965). This is directly related to the modern postulate that prostitutes do not conceive because of antisperm antibodies acquired by frequent contact with semen.
Testicular Autoimmunity
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Author : Masahiro Itoh
language : en
Publisher: Springer
Release Date : 2017-07-31
Testicular Autoimmunity written by Masahiro Itoh and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-31 with Medical categories.
This book addresses various aspects of testicular autoimmunity. It has long been suspected that testicular autoimmunity could be one of the causes of idiopathic male infertility. However, it is very difficult to estimate the incidence of testicular autoimmunity in men, as most male patients first realize they are infertile when they start trying to conceive a child, and there is a possibility that their testes may already exhibit the end stage of testicular autoimmunity, in which lymphocytic inflammation and immunoglobulin deposition in their testes subsided long ago and only the spermatogenic disorder remains. Therefore, autopsy or biopsy for testicular tissues in men before the end stage of testicular autoimmunity and investigations using testicular autoimmunity model animals are needed to determine the epidemiology of testicular autoimmunity. Accordingly, the book discusses “the immunological fragility of testis” with regard to male infertility, reviewing autopsy data in men and presenting experimental data using murine models of autoimmune orchitis that has been induced by immunizing with viable syngeneic testicular germ cells alone. Testicular autoimmunity in animals is also discussed. In summary, the book provides a wealth of valuable information, not only for researchers who are interested in immunologic male infertility, but also for clinical professionals who treat these patients at hospitals.
Infertility In The Male
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Author : Larry I. Lipshultz
language : en
Publisher: Cambridge University Press
Release Date : 2009-09-24
Infertility In The Male written by Larry I. Lipshultz and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-24 with Medical categories.
The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.
The Leydig Cell
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Author : Anita H. Payne
language : en
Publisher:
Release Date : 1996
The Leydig Cell written by Anita H. Payne and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Science categories.
Sertoli Cell Biology
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Author : Michael D. Griswold
language : en
Publisher: Academic Press
Release Date : 2014-11-19
Sertoli Cell Biology written by Michael D. Griswold and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-19 with Science categories.
Sertoli Cell Biology, Second Edition summarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions. This information is especially timely since the progress in the past few years has been exceptional and it relates to control of sperm production in vivo and in vitro. Fully revised Written by experts in the field Summarizes 10 years of research Contains clear explanations and summaries Provides a summary of references over the last 10 years
Genetics Of Human Infertility
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Author : P.H. Vogt
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2017-09-12
Genetics Of Human Infertility written by P.H. Vogt and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-12 with Medical categories.
Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.
Immune Infertility
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Author : Walter K.H. Krause
language : en
Publisher: Springer
Release Date : 2016-11-02
Immune Infertility written by Walter K.H. Krause and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-02 with Health & Fitness categories.
This book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.
Oxford Textbook Of Endocrinology And Diabetes
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Author : John A.H. Wass
language : en
Publisher: Oxford University Press, USA
Release Date : 2011-07-28
Oxford Textbook Of Endocrinology And Diabetes written by John A.H. Wass and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-28 with Medical categories.
Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.
Anatomy And Physiology
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Author : J. Gordon Betts
language : en
Publisher:
Release Date : 2013-04-25
Anatomy And Physiology written by J. Gordon Betts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-25 with categories.
Textbook Of Clinical Embryology
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Author : Kevin Coward
language : en
Publisher: Cambridge University Press
Release Date : 2013-10-31
Textbook Of Clinical Embryology written by Kevin Coward and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-31 with Medical categories.
The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.
