Immunological And Clinical Aspects Of Multiple Sclerosis
DOWNLOAD
Download Immunological And Clinical Aspects Of Multiple Sclerosis PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Immunological And Clinical Aspects Of Multiple Sclerosis book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Immunological And Clinical Aspects Of Multiple Sclerosis
DOWNLOAD
Author : R.E. Gonsette
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immunological And Clinical Aspects Of Multiple Sclerosis written by R.E. Gonsette and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Looking back is a luxury for which scientists normally have little time. This XXV Anniversary Symposium, however, gives the opportunity of reminding us that in Belgium, where the risk of developing multiple sclerosis is among the highest in the world, a great man to whom we all pay tribute, I mean Dr Ludo van Bogaert, in 1957, took the initiative in founding the Belgian Research Group for Multiple Sclerosis. It may sound immodest but since that time members of the Belgian Research Group happen to have an honourable record of important contributions to MS research, quite out of proportion to the financial support they received for it. Indeed, when compared to the situation in English speaking countries, funding of MS research has always been neglected in our country in spite of the fact that in 1958, acting on the advice of the Belgian Research Group, the Belgian National MS Society was founded with the specific object of collecting money for research as well as for social care. At that time, the difficulty in raising funds for research was partly due to the fact that solving the problem of MS appeared almost impossible. Scientists could apparently only too slowly improve their ability to prevent and cure the disease. Media were indifferent to MS which was considered to have no news value, and the public remained uninformed.
Immunological And Clinical Aspects Of Multiple Sclerosis
DOWNLOAD
Author : R. E. GONSETTE
language : en
Publisher:
Release Date : 1984
Immunological And Clinical Aspects Of Multiple Sclerosis written by R. E. GONSETTE and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with categories.
Immunological And Clinical Aspects Of Multiples Sclerosis Proceedings Of The Xxv Anniversary Symposium Of The Belgian Research Group For Multiple Sclerosis
DOWNLOAD
Author : R. E. Gonsette
language : en
Publisher:
Release Date : 1984
Immunological And Clinical Aspects Of Multiples Sclerosis Proceedings Of The Xxv Anniversary Symposium Of The Belgian Research Group For Multiple Sclerosis written by R. E. Gonsette and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Demyelination categories.
Clinical And Immunological Aspects Of Multiple Sclerosis
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 2011
Clinical And Immunological Aspects Of Multiple Sclerosis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
Multiple Sclerosis
DOWNLOAD
Author : Robert M Herndon, MD
language : en
Publisher: Demos Medical Publishing
Release Date : 2002-12-01
Multiple Sclerosis written by Robert M Herndon, MD and has been published by Demos Medical Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-01 with Medical categories.
Knowledge has been described as being like an expanding sphere with the volume of knowledge contacting a surface on the unknown. This new comprehensive review of the many fields of basic and clinical research that impact our understanding of multiple sclerosis has its basis in this premise. In doing research on MS, it is not enough to know clinical neurology or neurochemistry or neuroanatomy or pathology; it is important to understand the many other areas that relate to them. This volume provides an overview of MS-related research and will benefit many investigators in the field and help to advance our efforts to cure this, thus far intractable, disease. It is now more than 160 years since the first clinical-pathological descriptions of cases of multiple sclerosis and more than 130 years since the classic clinical description and development of diagnostic criteria by Charcot, yet MS remains an enigma. After decades of intense effort to find the cause, no cause has been clearly identified and the disease remains poorly understood. Despite the introduction of immunomodulatory therapies and immunosuppressive regimens, MS remains a devastating disease. While a great deal of progress has been made, much remains to be done. Our understanding of the disease remains limited, treatments remain inadequate, and comprehensive management all too rare. This volume is an overview of the basic sciences as they relate to MS and will provide clinicians and investigators a better understanding of the basic aspects of the disease. While it is possible to find excellent reviews of almost any aspect of MS, few attempts have been made to bring these very different aspects together in a single source. This volume is a companion to Multiple Sclerosis: Diagnosis, Medical Management, and Rehabilitation, edited by Drs. Jack S. Burks and Kenneth P. Johnson. Together, they represent an attempt to comprehensively cover the field of MS from basic research to comprehensive management and to provide a broad overview for those interested in understanding the disease better or in pursuing MS research.
Clinical Neuroimmunology
DOWNLOAD
Author : Syed A. Rizvi
language : en
Publisher: Springer Nature
Release Date : 2019-10-24
Clinical Neuroimmunology written by Syed A. Rizvi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-24 with Medical categories.
This comprehensive, up-to-date book is designed to make recent developments in neuroimmunology accessible to medical professionals in the field. The field of neuroimmunology is complex and rapidly evolving, especially with the current improvements in targeted biologic therapies. This resource concisely offers clear explanations of these scientific and clinical advancements. Divided into five parts, the book begins with an in-depth introduction to neuroimmunology and the principles of immunotherapy. Section two consists of eight chapters devoted to multiple sclerosis, including discussions on the clinical features of the disease as well as symptom management and diagnosis. Subsequent chapters then dive into other central nervous system inflammatory disorders such as neuromyelitis optica, autoimmune encephalopathies, and immunological aspects of cancer. Following this are two chapters that examine distinct aspects of autoimmune disorders of the peripheral nervous system. Finally, the book closes with a review on the neurologic manifestations, diagnostic approaches and treatments of the various systemic rheumatic diseases. Following its successful predecessor edition, Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders, Second Edition is positioned to be an invaluable asset to neurologists, residents and fellows, internists, and general practitioners who treat patients with neurologic disorders and other systemic autoimmune diseases.
Multiple Sclerosis
DOWNLOAD
Author : Frank Clifford Rose
language : en
Publisher: Demos Medical Publishing
Release Date : 1987
Multiple Sclerosis written by Frank Clifford Rose and has been published by Demos Medical Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.
Multiple sclerosis, in spite of being one of the commonest neurological diseases, is of unknown aetiology and its diagnosis is often doubtful. This volume is based on a symposium held at Charing Cross Hospital (1986) and looks at the immunological, diagnostic and therapeutic aspects of the disease.
Multiple Sclerosis
DOWNLOAD
Author : Alireza Minagar
language : en
Publisher: Biota Publishing
Release Date : 2014-09-01
Multiple Sclerosis written by Alireza Minagar and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-01 with Medical categories.
Multiple sclerosis [MS] is one of the most common auto-immune-mediated diseases of the human central nervous system [CNS] which affects young adults and usually causes significant neurological disability. Currently, the causes of MS are still unclear, a cure for MS remains elusive and the effectiveness of treatment varies significantly among individuals. Clinical features and neurological deficits stemming from this progressive neurological disease are diverse since MS potentially affects human CNS at all levels from brain to the end of spinal cord. The triggering event for development of MS remains unknown. Immunopathogenesis of MS involves a number of steps which include activation of peripheral leukocytes against putative CNS antigen(s), interactions of the activated leukocytes with inflamed cerebral endothelial cells, transendothelial migration of activated lymphocytes and macrophages to the CNS milieu, and further propagation of the massive immune response within the CNS. Such massive immune activation leads to loss of myelin-oligodendrocyte complex. Several immune cell types and mediators of the immune-inflammatory response actively contribute to pathogenesis of MS. Genetic factors are also believed to play a central role in the development of most forms of MS. Another important but much unrecognized and under-researched feature of MS immunopathology is “neurodegeneration.” Neuronal loss and axonal degeneration are the core components of irreversible and permanent CNS atrophy and disability in MS. What we call MS in reality is a heterogeneous group of diseases and at least four distinct immunopathological subtypes of MS with dissimilar responses to therapy with immunomodulatory agents exist. MS is a clinical diagnosis, however, its diagnostic process is much facilitated by utilization of laboratory and neuroimaging studies. Present therapies of MS are either immunomodulatory agents or immunosuppressive and mainly target the peripheral immune system with the intention to ameliorate the severity of acute relapses, decrease annual relapse rate, and improve MRI lesions. Currently, much research activity is being conducted to better understand the fundamental disease mechanisms of MS and find more effective and safer treatments for this incurable disease. This book presents an overview of MS as a disease with neuroinflammatory and neurodegenerative features and the authors discuss the most recent findings about MS and its treatment. Table of Contents: Introduction / Clinical Features of Multiple Sclerosis / Pathophysiology of Multiple Sclerosis / Neuroimaging of Multiple Sclerosis / Diagnosis of Multiple Sclerosis / Treatment of Multiple Sclerosis / Prognosis of Multiple Sclerosis / Concluding Remarks . References
Neuroimmunology
DOWNLOAD
Author : Amanda L. Piquet
language : en
Publisher: Springer Nature
Release Date : 2021-03-08
Neuroimmunology written by Amanda L. Piquet and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-08 with Medical categories.
This book provides a clinical focus on neuroinflammatory diseases as well as a review in pathophysiology and treatment approaches. Organized into six parts, the book begins with a basic review of the immune system and concepts for learning and treating neuroimmune conditions. The next four sections cover specific subfields of neuroimmunology and autoimmune neurology - the clinical and diagnostic features of multiple sclerosis, other autoimmune conditions of the central nervous system, autoimmune conditions of the peripheral nervous system, and systemic autoimmune conditions that affect the nervous system. To conclude, Section six discusses various clinical approaches to specific presentations in neuroimmunology, including pediatric demyelinating diseases. These sections provide practical clinical information to improve the reader’s knowledge in this complex field. The chapters are written by world renown authors with extensive knowledge to help provide up to date information. The full scope of autoimmune neurology is discussed, which is a unique feature of this book. Neuroimmunology serves as a resource for those in training including residents and fellows to provide clear clinical reasoning and background in a rapidly advancing field.
Multiple Sclerosis
DOWNLOAD
Author : Michael Olek
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-27
Multiple Sclerosis written by Michael Olek and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-27 with Medical categories.
A synthesis of current concepts about the evaluation, treatment, and future directions in MS. On the evaluation side, the authors review the use of MRI, magnetic resonance spectroscopy, functional MRI, and three-dimensional MRI, and consider the rapidly developing body of pathologic information they have yielded. On the treatment side, the focus is on recently approved medications (Novantrone), new indications for medications (CHAMPS Trial), medications in development (Oral Interferon Tau, Oral Copaxone, and Oral Cellcept), immunosuppressive therapy for both progressive disease and symptomatic therapy; the current medications for treating relapsing-remitting MS (Avonex, Betaseron, and Copaxone) are also discussed. For future directions, the authors present the current best thinking, as well as the latest discoveries in immunology relating to MS, including groundbreaking B-cell research and its applications to specific immunotherapies, and the use of immune markers for tracking the disease.