Immunological Influence On Human Fertility
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Immune Infertility
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Author : Walter K.H. Krause
language : en
Publisher: Springer
Release Date : 2014-12-13
Immune Infertility written by Walter K.H. Krause and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-13 with Health & Fitness categories.
Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the female partner. Immune reactions to sperm can contribute up to 2–30% of infertility. The sperm has both autoantigenic as well as isoantigenic potential, and is thus capable of p- ducing antisperm antibodies (ASAs) and sperm-reactive T cells in both infertile men and women. Also, over 75% vasectomized men produce autoantibodies to sperm that can cause a problem in regaining fertility even after successful re-anastomosis in vasovasostomy. Early claims regarding the incidence and involvement of ASAs in involuntary human infertility were probably overemphasized because of unreliable techniques and naivety concerning the complexity of the immune response and antigenic nature of the sperm cell. These factors, the lack of well-designed and controlled experimental studies, and the dearth of effective therapeutic modalities resulted in the confusion of the occurrence and importance of ASAs in human infertility. Consequently, evaluation of infertile couples for ASAs and their possible role in infertility was not considered a signifcant proposition. The development of more accurate assays and the discovery of mucosal immunity capable of responses independent of systemic immunity have caused inclusion of sperm cells and genital tract secretions in the analysis of ASAs.
Immunological Influence On Human Fertility
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Author : Barry Boettcher
language : en
Publisher: Academic Press
Release Date : 2014-05-12
Immunological Influence On Human Fertility written by Barry Boettcher and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Medical categories.
Immunological Influence on Human Fertility covers the proceedings of the Workshop on Fertility in Human Reproduction, held at the Department of Biological Science, University of Newcastle, Australia on July 11 -13, 1977. The book focuses on topics on the immunological control of human and animal fertility. The selection first discusses the zona pellucida as a possible target in immunocontraception, immunological aspects of vasectomy, and the clinical significance of antibodies to spermatozoa. Topics include performance and significance of the SCMC-test, antibodies and fertility after vasovasostomy, vasectomy and the blood-testis barrier, cellular immune response, active and passive immunization, and tissue and species specificity. The book then tackles the nature of the barrier to autoimmunity in the excurrent ducts of the mammalian testis, immune activities of the male and female reproductive tracts, and isolation of spermatozoal antigens. The manuscript examines the immunological capacity of the male genital tract, clinical significance of antibodies to antigens of the reproductive tract, immunological aspects of vasectomy, and antigens of human trophoblasts. The text also takes a look at the immunological and anti-tumor effects of orchidectomy, immune infertility and approaches to treatment, natural insemination as an immune phenomenon, and modified seminal plasma antigens and subfertility. The selection is a valuable source of information for researchers wanting to study the immunological control of human and animal fertility.
Immunological Influence On Human Fertility
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Author : Barry Boettcher
language : en
Publisher:
Release Date : 1977
Immunological Influence On Human Fertility written by Barry Boettcher and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Fertility, Human categories.
Immunology
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Author :
language : en
Publisher:
Release Date : 1991
Immunology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Communicable diseases categories.
Immunological Aspects Of Reproduction And Fertility Control
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Author : J.P. Hearn
language : en
Publisher: Springer
Release Date : 1980-07-31
Immunological Aspects Of Reproduction And Fertility Control written by J.P. Hearn and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980-07-31 with Medical categories.
The no-man's-land between reproductive physiology and immunology is becoming crowded. The last 10 years have seen a revolution in our under standing of many reproductive processes, brought about by the application of ever more sophisticated immunological methods. The increasing precision of these techniques has given us specific ways of assaying, enhancing or blocking hormonal mechanisms to yield more critical and interpretable information. In this volume eleven authors have presented the current status and future prospects of some immunological aspects of reproduction and fertility con trol. These include the relationships between mother and fetus, the diagnosis of pregnancy, the immunological complications seen in clinical management of human reproduction and some novel approaches for immunological control of fertility. We hope that in these chapters we have achieved an up-to-date account of a fast-moving field that calls on several disciplines. We intend the book to provide an adequate background and a current review for research workers and clinicians who wish both to understand the complex mechanisms involved and to develop improved scientific and clinical methods. We hope too that the student and newcomer will find this a useful reference book.
Immunological Influence On Human Fertility
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Author : Barry Boettcher
language : en
Publisher: Academic Press
Release Date : 1977-01-01
Immunological Influence On Human Fertility written by Barry Boettcher and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977-01-01 with Fertility, Human categories.
Immunological Approaches To Contraception And Promotion Of Fertility
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Author : G. P. Talwar
language : en
Publisher: Springer
Release Date : 1986-09
Immunological Approaches To Contraception And Promotion Of Fertility written by G. P. Talwar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-09 with Medical categories.
Contraceptive research has entered the new age of vaccines. Realistic prospects exist for the development of an entirely new battery of vaccines for use in human and veterinary medicine. Among them may be anti-fertility vaccines, based on physiological mechanisms applicable to either the female or male. This volume is a comprehensive review - a status report - of the subjects including fundamental work on the search for useful epitopes and ranging to applied vaccinology. One vaccine to prevent pregnancy, for use by women, has already been studied extensively. G.P. Talwar, the volume's editor and his colleagues in New Oelhi, India, published in 1976 a landmark series of papers describing the immunological properties of a preparation consisting of the alum-precipitated beta-subunit of human chorionic gonadotropin (hCG) chemically linked to tetanus toxoid. The principle of enhancing antigenicity of a self-protein by linkage of the epitope to a carrier protein was employed and tested clinically. These trials, carried out under the auspices of the Indian Council for Medical Research, were the first application of the carrier protein concept for a vaccine for human use. The encouraging results stimulated a wave of research not only on the use of hCG-based vaccines, but on other antigens as well.
Immunology Of Human Reproduction
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Author : James S. Scott
language : en
Publisher:
Release Date : 1976
Immunology Of Human Reproduction written by James S. Scott and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Medical categories.
Mechanisms Of Life History Evolution
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Author : Thomas Flatt
language : en
Publisher: OUP Oxford
Release Date : 2011-05-12
Mechanisms Of Life History Evolution written by Thomas Flatt and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-12 with Science categories.
Life history theory seeks to explain the evolution of the major features of life cycles by analyzing the ecological factors that shape age-specific schedules of growth, reproduction, and survival and by investigating the trade-offs that constrain the evolution of these traits. Although life history theory has made enormous progress in explaining the diversity of life history strategies among species, it traditionally ignores the underlying proximate mechanisms. This novel book argues that many fundamental problems in life history evolution, including the nature of trade-offs, can only be fully resolved if we begin to integrate information on developmental, physiological, and genetic mechanisms into the classical life history framework. Each chapter is written by an established or up-and-coming leader in their respective field; they not only represent the state of the art but also offer fresh perspectives for future research. The text is divided into 7 sections that cover basic concepts (Part 1), the mechanisms that affect different parts of the life cycle (growth, development, and maturation; reproduction; and aging and somatic maintenance) (Parts 2-4), life history plasticity (Part 5), life history integration and trade-offs (Part 6), and concludes with a synthesis chapter written by a prominent leader in the field and an editorial postscript (Part 7).
Infertility In The Male
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Author : Larry I. Lipshultz
language : en
Publisher: Cambridge University Press
Release Date : 2009-09-24
Infertility In The Male written by Larry I. Lipshultz and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-24 with Medical categories.
The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.
