Implications Of Ferroptosis Related Genes To The Genetics Of Cancer Development
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Implications Of Ferroptosis Related Genes To The Genetics Of Cancer Development
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Author : Lian Xiang Luo
language : en
Publisher: Frontiers Media SA
Release Date :
Implications Of Ferroptosis Related Genes To The Genetics Of Cancer Development written by Lian Xiang Luo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on with Science categories.
Proton And Carbon Ion Therapy
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Author : C-M Charlie Ma
language : en
Publisher: CRC Press
Release Date : 2012-10-09
Proton And Carbon Ion Therapy written by C-M Charlie Ma and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-09 with Science categories.
Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of proton and carbon ion therapy. It presents a thorough introduction for those new to the field while providing a helpful, up-to-date reference for readers already using the therapy in clinical settings.
Insights In Cancer Genetics And Oncogenomics 2022
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Author : Anton A. Buzdin
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-27
Insights In Cancer Genetics And Oncogenomics 2022 written by Anton A. Buzdin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-27 with Science categories.
Molecular Biology Of Prostate Cancer
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Author : Manfred Wirth
language : en
Publisher: Walter de Gruyter
Release Date : 2013-05-22
Molecular Biology Of Prostate Cancer written by Manfred Wirth and has been published by Walter de Gruyter this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-22 with Medical categories.
Recent Advances In The Molecular Genetics And Precision Medicine Of Lung Carcinoma
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Author : Mehdi Pirooznia
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-25
Recent Advances In The Molecular Genetics And Precision Medicine Of Lung Carcinoma written by Mehdi Pirooznia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-25 with Science categories.
Lung Carcinoma is the 2nd most common cancer worldwide, with more than 2.2 million cases recorded globally in the year 2020, as well as 1.8 million deaths. It is the most common cancer in men and the 2nd most common cancer in women, with an estimated lifetime risk of developing the disease of 1 in 15 for men and 1 in 17 for women. Whilst being the most prevalent cancer, it is important to note that smoking is the single biggest risk factor for developing Lung Cancer, with over 70% of cases being estimated to have been caused by tobacco smoke, and excessive smoking potentially leading to as much as a 25x increase in the likelihood of the disease developing. Mortality rates have been steadily dropping globally due to declining smoking rates, especially in younger generations who are now more aware of the potential dangers, but also because of the increasing advancements being made in our understanding of the disease. Improved screening methods mean many more cases are now caught earlier than they would otherwise have been, and our ever-advancing ranges of treatments can begin earlier than they could have previously. Recent advances in sequencing technology, computational approaches, and our biological understanding of lung cancer have revolutionized how we diagnose, prognosticate, and treat lung carcinoma. Genetic studies into this disease have revealed a plethora of information which can be used to combat the Cancer, such as novel biomarkers and gene signatures, as well as opening the door to more of a ‘personalized medicine’ approach.
Breast Cancer Metastasis And Drug Resistance
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Author : Aamir Ahmad
language : en
Publisher: Springer Nature
Release Date : 2019-08-27
Breast Cancer Metastasis And Drug Resistance written by Aamir Ahmad and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-27 with Medical categories.
Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.
Computational Approaches Applied To Cancer Genetics Immunogenomics And Immuno Oncology
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Author : Luis Zapata
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-30
Computational Approaches Applied To Cancer Genetics Immunogenomics And Immuno Oncology written by Luis Zapata and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-30 with Science categories.
Computational Methods For Multi Omics Data Analysis In Cancer Precision Medicine
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Author : Ehsan Nazemalhosseini-Mojarad
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-02
Computational Methods For Multi Omics Data Analysis In Cancer Precision Medicine written by Ehsan Nazemalhosseini-Mojarad and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-02 with Science categories.
Cancer is a complex and heterogeneous disease often caused by different alterations. The development of human cancer is due to the accumulation of genetic and epigenetic modifications that could affect the structure and function of the genome. High-throughput methods (e.g., microarray and next-generation sequencing) can investigate a tumor at multiple levels: i) DNA with genome-wide association studies (GWAS), ii) epigenetic modifications such as DNA methylation, histone changes and microRNAs (miRNAs) iii) mRNA. The availability of public datasets from different multi-omics data has been growing rapidly and could facilitate better knowledge of the biological processes of cancer. Computational approaches are essential for the analysis of big data and the identification of potential biomarkers for early and differential diagnosis, and prognosis.
The Role Of Iron In Cancer Progression
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Author : Maryam Mehrpour
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-04
The Role Of Iron In Cancer Progression written by Maryam Mehrpour and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-04 with Medical categories.
Biomedical Image Or Genomic Data Characterization And Radiogenomic Image Omics
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Author : Ming Fan
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-27
Biomedical Image Or Genomic Data Characterization And Radiogenomic Image Omics written by Ming Fan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-27 with Science categories.
Much of the emphasis in discussions about personalized medicine has been focused on the molecular characterization of tissue samples using microarray technology. However, as genetic differ between and within tumors and are quite heterogeneous, these techniques are limited. Imaging is noninvasive and is often used in routine clinical practice for disease diagnosis, treatment, and prognosis. Imaging is useful to guide disease therapy by providing a more comprehensive view of the entire lesion and it can be used on an ongoing basis to monitor lesion growth and progression or its response to treatment. The imaging includes but not limited to ultrasound, X-ray, computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET). Radiomics refers to the conversion of images to high dimensional data and the subsequent mining for characterization of biology and ultimately to improve disease management for patients. Radiogenomics investigates relationships between imaging features and genomics, which represents the correlation between the anatomical-histological level to the genomic level. With advanced artificial intelligence methods, especially deep learning, data processing, feature extraction and data integration have been greatly improved. The topic is about artificial intelligence methods in biomedical images and genomics data for disease diagnosis, treatment, and prognosis, as listed here: • Biomarker identification from biomedical images to predict disease diagnosis, treatment, and prognosis • Radiogenomics/image-omics in identifying imaging biomarkers associated with molecular characteristics of the disease. • Machine learning/deep learning methods in biomedical imaging or genomics for disease detection and precision medicine. • Prediction of histological characteristics of disease based on biomedical imaging. • Integration of radiomics and genomics features for disease diagnosis, prognosis, and prediction medicine • Multimodality images or multi-omics data integration methods