In Vivo Neuromethods
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In Vivo Neuromethods
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Author : Alan A. Boulton
language : en
Publisher: Humana Press
Release Date : 2010-10-28
In Vivo Neuromethods written by Alan A. Boulton and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-28 with Medical categories.
A superb collection of time-tested, key techniques for investigating nervous system function, as well as the actions of drugs on the nervous system. The methods range from authoritative treatment of such well-established techniques as recording electrical activity in the brain, to practical coverage of state-of-the-art methods, including neural transplantation and antisense technology. The techniques described are particularly suitable for studying the mechanisms of action of psychotropic drugs and drugs of abuse, as well as the etiology and pharmacotherapy of neuropsychiatric diseases and neurodegenerative disorders. Several of the methods detailed are highly useful in screening potential drugs for the treatment of depression, anxiety disorders, schizophrenia, and Parkinson's and Alzheimer's disease.
Experimental Neurotoxicology Methods
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Author : Jordi Llorens
language : en
Publisher: Springer Nature
Release Date : 2021-07-23
Experimental Neurotoxicology Methods written by Jordi Llorens and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-23 with Medical categories.
This volume explores the latest methods that seek to address the vital questions being asked in neurotoxicology research. The chapters in this book cover a variety of available methods from the molecular level to the organism level, and both in vitro and in vivo approaches, including alternative model organisms. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Experimental Neurotoxicology Methods is a valuable resource for both young and experienced researchers who are looking for guidance to implement these methods in their laboratories or for understanding the data generated through these techniques.
In Vitro Neurochemical Techniques Neuromethods
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Author : Alan A. Boulton
language : en
Publisher:
Release Date : 1999
In Vitro Neurochemical Techniques Neuromethods written by Alan A. Boulton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
In Vitro Neurochemical Techniques is the third work updating and expanding the best-selling inaugural volume of Humana Press's warmly received Neuromethods series, General Neurochemical Techniques (vol. 1). The key techniques detailed in this new edition encompass the breadth of neurochemical and molecular neurobiology research, ranging from the isolation of neuronal genes and the study of their expression to the analysis of receptor-ligand interactions, to the characterization of the consequences of receptor activation. The methods include electrophysiological techniques to explore the functional properties of receptors present in the membranes of excitable cells, methods to isolate novel genes central to neurobiological processes, and protocols to perform in situ hybridization histochemistry. Other methods cover the measurement of changes in gene expression, the rapid identification of gene polymorphisms, and the identification and characterization of second messenger pathways. The companion volumes, In Vivo Neuromethods and Cell Neurobiology Techniques, cover both in vivo methods and in vitro cell neurobiology approaches. Like the original, all three cutting-edge works will prove exceptionally useful to those basic and clinical neuroscientists who want to expand the range of their current research or develop competence in complementary methods.
In Vitro Neurochemical Techniques
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Author : Alan A. Boulton
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-06
In Vitro Neurochemical Techniques written by Alan A. Boulton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-06 with Medical categories.
In Vitro Neurochemical Techniques is the third work updating and expanding the best-selling inaugural volume of Humana Press's warmly received Neuromethods series, General Neurochemical Techniques (vol. 1). The key techniques detailed in this new edition encompass the breadth of neurochemical and molecular neurobiology research, ranging from the isolation of neuronal genes and the study of their expression to the analysis of receptor-ligand interactions, to the characterization of the consequences of receptor activation. The methods include electrophysiological techniques to explore the functional properties of receptors present in the membranes of excitable cells, methods to isolate novel genes central to neurobiological processes, and protocols to perform in situ hybridization histochemistry. Other methods cover the measurement of changes in gene expression, the rapid identification of gene polymorphisms, and the identification and characterization of second messenger pathways. The companion volumes, In Vivo Neuromethods and Cell Neurobiology Techniques, cover both in vivo methods and in vitro cell neurobiology approaches. Like the original, all three cutting-edge works will prove exceptionally useful to those basic and clinical neuroscientists who want to expand the range of their current research or develop competence in complementary methods.
In Vivo Neuropharmacology And Neurophysiology
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Author : Athineos Philippu
language : en
Publisher: Humana
Release Date : 2018-06-08
In Vivo Neuropharmacology And Neurophysiology written by Athineos Philippu and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-08 with Medical categories.
This volume presents classical approaches to in vivo neuropharmacology and neurophysiology, such as c-fos, electrochemistry, microdialysis microstimulation, and push-up superfusion. It also explores exciting new methods for behavioral analysis, and techniques based on optogenetics and non-invasive magnetic resonance imaging. The chapters of this book cover topics such as principles of stereotaxy, pharmaco-based fMRI and neurophysiology in humans and non-human primates, electrical nerve stimulation and central microstimulation, involvement of neurotransmitters in mnemonic processes, the impact of cannabinoids on motor activity, as well as the involvement of nitric oxide in neurotoxicity produced by psychostimulant drugs. Each chapter also discusses difficulties, tips, tricks, and precautions to take. Neuromethods series style chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Cutting-edge and practical, In Vivo Neuropharmacology and Neurophysiology is a valuable resource for experienced and less experienced investigators of brain function and brain disorders.
Cell Neurobiology Techniques
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Author : Alan A. Boulton
language : en
Publisher: Neuromethods
Release Date : 1999
Cell Neurobiology Techniques written by Alan A. Boulton and has been published by Neuromethods this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
The cutting-edge techniques detailed here include those that are particularly popular in multidisciplinary neuroscience research. There are readily reproducible methods for establishing neural cell cultures, measuring enzymes and their inhibitors, and using quantitative autoradiography to study monoamine uptake sites and receptors in the brain. Additional methods cover the use of flow cytometry to study developmental neurobiology, applications of magnetic resonance spectroscopy (MRS) to human brain metabolism, and the study of drug metabolism. Together with its companion volumes, In Vivo Neuromethods and In Vitro Neurochemical Techniques, all three cutting-edge works will prove exceptionally useful to those basic and clinical neuroscientists who want to expand the range of their current research or develop competence in complementary methods.
Cell Neurobiology Techniques Neuromethods
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Author : Alan A. Boulton
language : en
Publisher:
Release Date : 1999
Cell Neurobiology Techniques Neuromethods written by Alan A. Boulton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
The cutting-edge techniques detailed here include those that are particularly popular in multidisciplinary neuroscience research. There are readily reproducible methods for establishing neural cell cultures, measuring enzymes and their inhibitors, and using quantitative autoradiography to study monoamine uptake sites and receptors in the brain. Additional methods cover the use of flow cytometry to study developmental neurobiology, applications of magnetic resonance spectroscopy (MRS) to human brain metabolism, and the study of drug metabolism. Together with its companion volumes, In Vivo Neuromethods and In Vitro Neurochemical Techniques, all three cutting-edge works will prove exceptionally useful to those basic and clinical neuroscientists who want to expand the range of their current research or develop competence in complementary methods.
Electroporation Methods In Neuroscience
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Author : Tetsuichiro Saito
language : en
Publisher: Humana
Release Date : 2016-10-05
Electroporation Methods In Neuroscience written by Tetsuichiro Saito and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-05 with Medical categories.
This volume describes the methods of both in vivo and in vitro electroporation using ferrets, rats, mice, chickens, and zebrafish. Recent advances of experiments using the tetracycline-regulated gene expression and Tol2 transposon systems are also included. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Practical and authoritative, Electroporation Methods in Neuroscience serves to aid scientists in the further study into this crucially important way to study cells.
Voltammetric Methods In Brain Systems
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Author : Alan A. Boulton
language : en
Publisher: Humana Press
Release Date : 2010-11-10
Voltammetric Methods In Brain Systems written by Alan A. Boulton and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-10 with Medical categories.
Efforts to measure neurotransmitters and related s- cies in living brain tissue by faradic electrochemistry began in earnest in the early 1970s. During the ensuing years, s- eral monographs and various symposia on the subject have appeared. The present volume of Neuromethods, Voltammetric Methods in Brain Systems, can be considered different from previous offerings in several respects. The methodology of in vivo electrochemistry has now reached a stable level of maturity. It is no longer necessary to convince interested re- ers that the techniques can measure, with specified degrees of reliability, certain neurotransmitters and metabolites in the extracellular fluid space. Moreover, the basic approaches of electroanalytical measurements are more widely appre- ated by neuroscientists and one need not explain in tutorial fashion the details of oxidative electrochemistry. Nevert- less, in keeping with the nature of the Neurumethods series, this is a “how to” volume and readers will find ample detail on the preparation of electrodes, practical experimental details, and the interpretation of results. But the emphasis is strongly on the application of voltammetric methods. The first two chapters deal with fundamentals inherent in employing in vivo electrochemical measures. The first - ticle offers an authoritative account of our understanding of the surface states of carbon and carbon fiber electrodes. It provides a rationale for the various pretreatments that have allowed the “tuning” of electrode properties to obtain sen- tivity and fast response times.
Experimental And Translational Methods To Screen Drugs Effective Against Seizures And Epilepsy
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Author : Divya Vohora
language : en
Publisher: Humana
Release Date : 2021-06-23
Experimental And Translational Methods To Screen Drugs Effective Against Seizures And Epilepsy written by Divya Vohora and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-23 with Medical categories.
This volume discusses the latest experimental and clinical approaches to study seizures and epilepsy. Chapters in this book cover detailed protocols for ex vivo and in vitro experimental models and widely-used in vivo (acute and chronic seizure) models in epilepsy research. Chapters also cover techniques to screen the effective leads for the treatment of refractory seizures of pharmacoresistant epilepsy and invertebrate, non-mammalian models. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy is a valuable resource for researchers, in both industry and academia, interested in learning about this important and developing field.